Search results for "RELATION"
showing 10 items of 10542 documents
Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action
2015
Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoates were screened against rhodesain and human cathepsins B and L, and were found to be potent and selective inhibitors of rhodesain. Among them (S,E)-ethyl 5-((S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanamido)-7-methyl-4-oxooct-2-enoate (6) was the most potent, with an IC50 value of 16.4 nm and kinact/Ki=1.6×106 m−1 s−1 against rhodesain. These dipeptidyl enoates display a reversible mode of inhibition at very low concentrations and an irreversible mode at higher concentrations. Inhibition…
Teacher emotional support in relation to social competence in preschool classrooms
2020
The present study aimed to investigate the associations between teachers’ observed emotional support and social competence among Finnish pre-schoolers (6-year-olds). The quality of emotional support was observed using the Classroom Assessment Scoring System Pre-K in 47 preschool classrooms twice across the preschool year. Teachers rated children’s social competence in autumn and again in spring, using the Multisource Assessment of Social Competence Scale (MASCS), which produced sum scores for cooperating skills, empathy, impulsivity, and disruptiveness. Consistent with the transactional model, we specified reciprocal (auto-regressive and cross-lagged) relationships within a Multilevel Struc…
The role of tennis coaches in regulating their players' emotional states : an exploratory study
2014
During the past few decades, the ability to perceive, understand, and regulate emotions efficiently has received widespread attention in sport settings (Hanin, 2000; 2004; Robazza, Pellizzari, & Hanin, 2004). Moreover, this line of research has mainly focused on the intrapersonal aspect of emotions. The aim of the present study was to examine the role of tennis coaches in regulating their players’ emotional states. The present study explored (a) tennis players’ emotional states related to their best and worst performances, (b) coaches’ accuracy in assessing players’ emotional experiences within these performances, and (c) self- and interpersonal emotional regulation strategies of tennis coa…
From Rationality to Emotionally Embedded Relations: Envy as a Signal of Power in Stakeholder Relations
2015
Although stakeholder salience theory has received a great deal of scholarly attention in the business ethics and management literature, the theory has been criticized for overemphasizing rationality in managerial perceptions. We argue that it is important to better understand what socially constructed emotions signal in business relations, and we posit the role of envy as a discursive resource used to signal and construct the asymmetrical power relations between small business owner–managers and their stakeholders. Our study is based on a qualitative study on discursive accounts elicited from 33 interviews with small business owner–managers in Finland. Our study makes two primary contributi…
Two-particle transverse momentum correlations in pp and p-Pb collisions at energies available at the CERN Large Hadron Collider
2023
Two-particle transverse momentum differential correlators, recently measured in Pb--Pb collisions at energies available at the CERN Large Hadron Collider (LHC), provide an additional tool to gain insights into particle production mechanisms and infer transport properties, such as the ratio of shear viscosity to entropy density, of the medium created in Pb-Pb collisions. The longitudinal long-range correlations and the large azimuthal anisotropy measured at low transverse momenta in small collision systems, namely pp and p-Pb, at LHC energies resemble manifestations of collective behaviour. This suggests that locally equilibrated matter may be produced in these small collision systems, simil…
Gendered Work-life Ideologies among IT Professionals
2022
The study investigates the discourses IT professionals use to produce work–life relations. We focus on work–life ideologies and explore the agencies produced, as well as whether and how they are gendered. Our data were collected in interviews with 24 women and men working in the IT industry in Finland. Our results show, first, that work–life relations were constructed discursively through two different work–life ideologies, and second, that these ideologies produced different gendered agencies in reconciling work with life. In our study, work–life talk produced different positions for women and men, which were influenced by gendered norms and social expectations. We conclude that gendered a…
A different glimpse into mobilities: On the interrelations between daily spatial mobility and social mobility
2017
We explore the link between daily spatial mobility and social mobility, taking changes in the contemporary labor market and family as examples. We propose a new theoretical approach to mobility that is defined as a productive force of social labor. Analyzing the relationship between daily spatial mobility and social mobility, we show that spatial mobility has become a strategy of compensation for the lack of social mobility. Explanations for the increase in daily spatial mobility are also provided. Lastly, we reveal how spatial mobility has the capacity to produce major social change, taking the family as an example. peerReviewed
Working while studying: does it lead to greater attachment to the regional labour market?
2017
This chapter studies the link between working while studying and migration. Understanding this link is important because policy-makers are often calling for actions that would cut down the hours students spend on working to shorten the graduation time. The chapter’s analysis focuses on graduates from Finnish universities, polytechnics and vocational schools in 1991–2004. It uses rich register-based longitudinal microdata constructed by Statistics Finland, and find a negative relationship between working while studying and graduate migration. An increase in student employment can thus partly explain the decline in geographic mobility among Finnish graduates from higher education.
Posting and agency work in British construction and hospitality: the role of regulation in differentiating the experiences of migrants
2017
This article engages with IHRM debates on the transnational regulation of labour, exploring how migration policy and work fragmentation affect employment dynamics in multi-employer settings. It dra...
Agency of labour in a flexible pan-European labour market : a qualitative study of migrant practices and trade union strategies in the Netherlands
2015
Regulatory frameworks on intra-EU mobility and flexible cross-border employment relations have stimulated competition on labour costs by recruiting migrants via cheaper labour market regimes. While it allows firms to remunerate migrants under different terms and conditions, blurring regulatory boundaries also generates opportunities for non-compliance, resulting in violations of migrant labour rights across Europe. Against this background, this thesis explores the agency of labour, more specifically of temporary migrant workers and unions, and the ways they cope with and respond to the competitive dynamics of the pan- European labour market. This study draws on 90 qualitative interviews wit…