Search results for "RELEASE"

showing 10 items of 602 documents

Inter-individual retronasal aroma release variability during cheese consumption: Role of food oral processing

2014

The aim of our study was to explain inter-individual differences on in vivo aroma release during cheese consumption by oral physiological parameters. To reach this objective, 34 subjects were recruited. Their salivary flow, oral volume and velum opening were determined. Six cheddar-based melted cheeses with different fat levels and firmness were flavoured with nonan-2-one.(NO) and ethyl propanoate (EP). During their consumption (free protocol), in vivo retro nasal aroma release was followed by Atmospheric Pressure Chemical lonisation-Mass Spectrometry (APCI-MS). Chewing activity was evaluated by electromyography recordings. Bolus saliva content, mouth-coating, and bolus rheology were also d…

Salivainter individual variability030309 nutrition & dieteticsFat content[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionFood consumption03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyBolus (medicine)[SDV.IDA]Life Sciences [q-bio]/Food engineeringin vivo aroma releaseAroma compoundFood scienceAromaNo release2. Zero hunger0303 health sciencesfood oral processingbiologyChemistry[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringEthyl propanoatefood and beverages04 agricultural and veterinary sciencesbiology.organism_classification040401 food sciencemouth coating[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionmodel cheesesFood Sciencechewing activity
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Molecular mechanisms of aroma persistence: From noncovalent interactions between aroma compounds and the oral mucosa to metabolization of aroma compo…

2021

International audience; The present study aims to reveal the molecular mechanisms underlying aroma persistence, as it plays a major role in food appreciation and quality. A multidisciplinary approach including ex vivo experiments using a novel model of oral mucosa and saliva as well as in vivo dynamic instrumental and sensory experiments was applied. Ex vivo results showed a reduction in aroma release between 7 and 86% in the presence of the thin layer of salivary proteins covering the oral mucosa (mucosal pellicle). This reduction was explained by hydrophobic interactions involving the mucosal pellicle and by the ability of oral cells and saliva to metabolize specific aroma compounds. The …

Salivaproton transfer reaction-mass spectrometry (PTR-MS)Thin layeraroma perception01 natural sciencesdynamic sensory evaluationAnalytical ChemistryPersistence (computer science)0404 agricultural biotechnologyIn vivomedicine[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyOral mucosaSalivary Proteins and PeptidesSalivaAromaVolatile Organic CompoundsbiologyChemistry010401 analytical chemistryMouth Mucosafood and beveragesafter-odour04 agricultural and veterinary sciencesGeneral Medicinebiology.organism_classification040401 food science0104 chemical sciencesmedicine.anatomical_structureBiochemistrymucosal pelliclearoma releaseOdorantsSalivary Proteins[SDV.AEN]Life Sciences [q-bio]/Food and NutritionEx vivoFood Science
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The role of saliva in aroma release and perception

2017

Aroma perception is an important factor driving food acceptance. Volatile organic compounds (VOCs) are released from the food matrix and then reach the receptors located in the nasal cavity, leading to their perception. These steps are closely dependent on the physicochemical properties of the volatile compounds and the food matrix, but also on human physiology. Among the different physiological parameters involved, the literature reports that saliva has various effects on VOCs and therefore appears as a major actor impacting the perception of aroma. This article reviews how saliva takes part in aroma release, considering both in vitro and in vivo approaches, and how it may affect perceptio…

Salivavolatile organic compound[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionmedia_common.quotation_subjectsalivary proteinsprotéine salivaireAnalytical Chemistry0404 agricultural biotechnologyPerceptionvolatile organic compoundsHumansflaveurFood sciencesaliveAromamedia_commonenzymatic reactionAffect perceptionMolecular interactionssalivabiologyChemistryenzymatic conversioncomposé organique volatilFood acceptancefood and beverages04 agricultural and veterinary sciencesGeneral MedicineHuman physiologymucinslibération d'arômeinteractionsbiology.organism_classification040401 food scienceflavourBiochemistryaroma releaseOdorantsréaction enzymatiquePerceptionIndirect impact[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood Science
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STRUCTURAL AND FUNCTIONAL RESPONSES OF FISH ASSEMBLAGES TO DIFFERENT DRIVERS OF CHANGE

Biotic and abiotic factors synergistically act on natural systems. As a result ecological communities adjust their structural and functional responses to persist in a given area. Worldwide, marine ecosystems have been changing through time with increasing anthropogenic pressure in the last centuries leading to only 13.2% of the total marine environments in a ‘pristine’ state. The consequences of direct and indirect anthropogenic pressures may have on marine organisms can largely differ, with both negative and positive effects of drivers of change of human origin. In the span of three years for my PhD thesis, I performed different experiments with the main goal of examining how direct or ind…

Settore BIO/07 - EcologiaFish assemblageMesopredator ReleaseOcean AcidificationMarine Protected Area
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Flavonoids against the SARS-CoV-2 induced inflammatory storm

2021

The disease severity of COVID-19, especially in the elderly and patients with co-morbidities, is characterized by hypercytokinemia, an exaggerated immune response associated with an uncontrolled and excessive release of proinflammatory cytokine mediators (cytokine storm). Flavonoids, important secondary metabolites of plants, have long been studied as therapeutic interventions in inflammatory diseases due to their cytokine-modulatory effects. In this review, we discuss the potential role of flavonoids in the modulation of signaling pathways that are crucial for COVID-19 disease, particularly those related to inflammation and immunity. The immunomodulatory ability of flavonoids, carried out …

Settore BIO/17 - Istologia0301 basic medicinePhytochemicalsAnti-Inflammatory AgentsAnti-inflammatory effectsInflammationRM1-950ReviewCytokine stormProinflammatory cytokineImmunomodulationEndothelial activation03 medical and health sciences0302 clinical medicineImmune systemAnimalsHumansMedicineDipeptidyl peptidase-4InflammationFlavonoidsPharmacologySARS-CoV-2business.industryfungiCOVID-19food and beveragesInflammasomeGeneral Medicinemedicine.diseaseCOVID-19 Drug Treatment3. Good health030104 developmental biology030220 oncology & carcinogenesisImmunologyTherapeutics. Pharmacologymedicine.symptomSignal transductionCytokine Release SyndromebusinessCytokine stormmedicine.drugBiomedicine & Pharmacotherapy
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POLYSACCHARIDE-POLYAMINOACID HYDROGEL FILMS FOR POTENTIAL CORNEAL CELL RELEASE

2009

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoHIDROGELS CORNEAL RELEASE.
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MODIFIED PEPTIDE RELEASE FROM NEW IN SITU GEL FORMING COPOLYMERS BASED ON POLYLACTIDE AND POLYASPARTAMIDE

2008

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoPEPTIDE RELEASE GEL POLYASPARTAMIDE POLYESTER
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Sviluppo di spugne bioerodibili multifunzionali per la promozione di processi riparativi mediante il rilascio controllato di agenti antibiotici e ant…

2023

La salute delle strutture molli e dure del cavo orale è essenziale non solo per preservare le funzioni ad esse direttamente associate, ma anche per promuovere la salute generale dell’organismo. Tra le problematiche di maggiore interesse clinico a carico della cavità orale ritroviamo: i) le complicazioni post-operatorie che possono verificarsi a seguito di comuni avulsioni dentali che, se non trattate tempestivamente, possono sfociare in gravi parodontiti; ii) i fenomeni di osteonecrosi a carico di mascella e mandibola associate a trattamenti farmacologici nonché alla radioterapia; iii) il carcinoma orale a cellule squamose (OSCC) che è tra i più aggressivi tumori del collo e della testa, ca…

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoSettore MED/28 - Malattie Odontostomatologicheoral disease polyphenols drug delivery system nanostructured lipid carrier nanocomposite polymeric microparticle spray drying 3D-printed scaffold wound healing controlled drug release kinetic evaluation.
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AMPHIPHILIC GRAFT COPOLYMER OF HYALURONIC ACID AND POLYLACTIC ACID FOR PULMONARY DELIVERY OF AMPHOTERICIN B

2009

Settore CHIM/09 - Farmaceutico Tecnologico Applicativograft copolymer hyaluronic acid polylactic acid drug release
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Novel Drug Delivery System for Treatment-Resistant Schizophrenia

2021

Settore CHIM/09 - Farmaceutico Tecnologico Applicativotreatment-resistant schizophrenia clozapine oral transmucosal delivery solid dosage form unidirectional delivery sustained release profile
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