Search results for "RELEVANCE"
showing 10 items of 500 documents
Frontiers of metal-coordinating drug design
2020
INTRODUCTION: The occurrence of metal ions in biomolecules is required to exert vital cellular functions. Metal-containing biomolecules can be modulated by small-molecule inhibitors targeting their metal-moiety. As well, the discovery of cisplatin ushered the rational discovery of metal-containing-drugs. The use of both drug types exploiting metal–ligand interactions is well established to treat distinct pathologies. Therefore, characterizing and leveraging metal-coordinating drugs is a pivotal, yet challenging, part of medicinal chemistry. AREA COVERED: Atomic-level simulations are increasingly employed to overcome the challenges met by traditional drug-discovery approaches and to compleme…
Sensación de inacabado y experiencias “not just right” como motivadoras de los síntomas obsesivo-compulsivos
2016
The sense of incompleteness, “not just right” experiences and “just right” symptoms are considered motivational variables of obsessive-compulsive symptoms. This study examines the relationships between these “new” constructs and Obsessive-Compulsive Disorder (OCD) related variables (symptoms, dysfunctional beliefs, perfectionism, and intolerance to uncertainty), in comparison to its association with emotional non-OCD psychopathology. The results from 267 individuals who completed self-reports indicate that individuals at risk of developing OCD score higher on the main constructs of the study than those not at risk. Only the variables incompleteness, not just right experiences and just right…
La formación del futuro docente a través de la interdisciplinariedad y la educación integral
2020
The Plastic Expression and the Musical Expression have a special relevance for the integral formation of the students of Early Childhood Education. Training in or from these areas of knowledge should be continued in the next stage, Primary Education, through the study of the so-called Area of Artistic Education (includes the subjects of Plastic and Music). The future teachers of Early Childhood Education should consider training in artistic education not only as an interrelated whole that guarantees the integral formation of the students of this educational stage, but as tools that favor and enhance the development of all fundamental areas (cognitive, motor, linguistics, etc.). This article…
Training for gender equity: an experience through choreographies in Early Childhood Education
2020
INTRODUCCIÓN. En Educación Infantil, el trabajo de los denominados temas transversales toma especial relevancia porque permiten reforzar las destrezas del alumnado en diferentes áreas, que contribuyen a un desarrollo adecuado durante la Educación Primaria. Los contenidos de la asignatura “Procesos musicales en Educación Infantil”, de tercer curso del Grado de Maestra de Educación Infantil, permiten el trabajo de esos temas, concretamente, las coreografías. Éstas pueden ser utilizadas como herramientas lúdicas que garantizan no sólo el trabajo de las habilidades motrices básicas, sino también la equidad, la educación cívica y moral…, por el contenido de las canciones que pueden ser utilizada…
Earnings sustainability, economic conditions and the value relevance of accounting information
2013
Summary This study demonstrates that the value relevance of accounting information is influenced by the ability to capitalize investments in valuable resources. We use data from Sweden to show that firms that operate in industries in which accounting conservatism limits this capitalization display lower value relevance as a result of more unsustainable earnings components. However, when controlling for the different properties of sustainable and unsustainable earnings components, the difference vanishes. Moreover, we show that firms operating in industries in which more investments are immediately expensed display systematic temporal variations in the level of value relevance. We contend th…
The value relevance of losses revisited: the importance of earnings aggregation
2011
Accepted version of an article published in the journal: Global Business and Economics Review. Also available from the publisher at: http://dx.doi.org/10.1504/GBER.2011.040728 Prior research has suggested that earnings explain a larger portion of the variation in stock returns when disaggregated into components. This study shows that the increase in explanatory power stems primarily from disaggregation of negative earnings. When accounting earnings are sufficiently disaggregated into items, there is no longer a statistical difference in the value relevance of positive and negative earnings. Thus, negative earnings are also useful to stock investors. The findings are attributed to earnings p…
The Agenda and Relevance of Recent Research in Microfinance
2005
This paper studies recent research efforts in the field of microfinance. Two questions guide the study: What is the agenda of recent research efforts? And, for who is the research relevant? As for the agenda the “yin and yang” of microfinance; impact and sustainability, continue to influence most research efforts. The study illustrates that microfinance attracts mainly the interest of development researchers and journals. Accordingly the researchers seem mainly to interact with the donors’ and practitioners’ communities. The research produced seems to be relevant for them and less so for the governmental and banking communities. The paper concludes proposing the design of a new research age…
Older Peruvian Migrants’ Capacity and Desire to Send Remittances from Spain
2016
This article draws on the conceptual framework of capacity and desire to analyze the remitting behavior of older Peruvian migrants in Spain. Cross-sectional survey data are explored using regression analysis to estimate how local and transnational factors relate to the sending of remittances. To reveal the complexities involved in this activity, the findings are discussed in the light of qualitative data gathered through semi-structured interviews with older Peruvian migrants in the metropolitan area of Barcelona. Results show that economic integration and transnational ties and practices are strong predictors for the sending of remittances, with local language skills being of intermediate …
Exploring the relationship between Information and Communication Technologies (ICT) and academic performance: A multilevel analysis for Spain
2021
Abstract With the world becoming increasingly digitalized, determining the relationship between the use of Information and Communication Technologies (ICT) and educational outcomes takes on special relevance for guiding educational policy decisions in a reasoned way. The objective of this research is to explore the relationship between different types of ICT use at school and at home, students' attitudes towards ICT, and academic performance, as well as to see if these associations differ according to the level of performance of the students. For this purpose, we apply multilevel regression models and quantile regression models with data from the Programme for International Student assessme…
The adjustment of bank ratings in the financial crisis: International evidence
2018
Abstract This paper analyses the adjustment of bank ratings which occurred in the United States, some European countries and Japan as a result of the financial crisis. We use a methodology which allows us to decompose the observed change in the rating into an effect associated with the change in agency rating policies (understood in a broad sense) and into another effect associated with the situation of bank assets. The results obtained show that with the crisis there was a generalised fall in the ratings, caused by both a worsening of the bank asset situation and the hardening of rating policies. Specifically, we find that 39.95% and 19.25% of the fall in ratings in the United States and E…