Search results for "REPERTOIRE"

Maahanmuuttajien kielitaito - yhteiskunnan resurssi vai yksilön kätköissä oleva pääoma? : esimerkkinä toisen polven suomenunkarilaiset

2014

The language policy of the European Union has the goal that every citizen will be bilingual and everybody will be able to communicate in two diQ erent languages besides one’s mother tongue. The aim of this article is to investigate the conditions for reaching these goals among people with immigrant backgrounds. The article provides an overview of bilingualism among one group of adults with Hungarian background in Finland. The focus is on language repertoire (e.g. the self-assessed language pro+ ciency), language choice between Finnish and Hungarian, the role of the minority language in their everyday lives and the future prospect for maintenance of Hungarian. The entire article is based on …

"Me ollaan mukana tässä experimentissä" : lingvististiska resurser och språkpraktiker i tvåspråkiga ungdomssamtal i Haparanda, Stockholm och Helsingf…

2017

The thesis explores bilingual adolescents’ language use, linguistic resources, and language practices in interaction at three junior high schools in Haparanda, a Swedish town on the country’s northeastern border with Finland. A comparison is also made with interaction among bilingual adolescents at two Sweden-Finnish junior high schools in Stockholm and at one Swedish-speaking junior high school in Helsinki. The aim of the study is to increase our knowledge of bilingual adolescents’ interaction practices and language repertoires, i.e. translanguaging, in interaction. The primary data consists of close to eleven hours of video- and audio-recorded informal group and pair conversations. The da…

Age and immunity

2006

Abstract Longitudinal studies are defining progressive alterations to the immune system associated with increased mortality in the very elderly. Many of these changes are exacerbated by or even caused by chronic T cell stimulation by persistent antigen, particularly from Cytomegalovirus. The composition of T cell subsets, their functional integrity and representation in the repertoire are all markedly influenced by age and by CMV. How these findings relate to epidemiological, functional, genetic, genomic and proteomic studies of human T cell immunosenescence was the subject of intense debate at an international conference held just before Christmas 2005 in the Black Forest.

Prediction of Specific TCR-Peptide Binding From Large Dictionaries of TCR-Peptide Pairs

2019

Abstract The T cell repertoire is composed of T cell receptors (TCR) selected by their cognate MHC-peptides and naive TCR that do not bind known peptides. While the task of distinguishing a peptide-binding TCR from a naive TCR unlikely to bind any peptide can be performed using sequence motifs, distinguishing between TCRs binding different peptides requires more advanced methods. Such a prediction is the key for using TCR repertoires as disease-specific biomarkers. We here used large scale TCR-peptide dictionaries with state-of-the-art natural language processing (NLP) methods to produce ERGO (pEptide tcR matchinG predictiOn), a highly specific classifier to predict which TCR binds to which…

Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space

2019

Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical element of successful vaccines and targeted immunotherapies. However, the underlying principles of this "convergence" of adaptive immunity among different individuals remain poorly understood. To quantitatively describe epitope immunogenicity, here we propose a supervised machine learning framework generating probabilistic estimates of immunogenicity, termed "immunogenicity scores," based on the numerical features computed through sequence-based simulation approximating the molecular scanning process of peptides presented onto major histocompatibility complex (MHC) by the human T cell receptor (T…

Professional communicative repertoires and trajectories of socialization into global working life

2013

Young People's Emerging Multilingual Practices : Learning Language or Literacy, or Both?

2019

Research on language learning and research on literacy are typically seen as two separate strands of enquiry and thus the concepts of language and literacy have traditionally been kept apart. This is partly due to epistemological questions related to language and literacy. In this chapter, I will discuss these concepts in the context of multilingualism. Approaching multilingual language use from the perspective of literacy practices enables us to look beyond language to social practices and to examine the relationship between the concepts of language and literacy, literacy practices and language learning. Two data sets are used to illustrate how language, literacy, and language learning are…

The discursive construction of authenticity : resources, scales and polycentricity in Finnish hip hop culture

2014

Kunnon muslimi ja kunnon kansalainen : turkkilaisten imaamisaarnaajalukioiden oppikirjojen ilmentämän maailmankatsomuksen analyysi

2017

This qualitative study aims to analyse the worldview that emerges in the textbooks of Turkish imam and preacher high schools (úmam hatip lisesi). The study material consists of eight textbooks that belong to the vocational religious education of Turkish imams. All of the textbooks were published around 2010. In this study, theoretical considerations regarding the essence of worldview (Weltanschauung) are summarized into an existential model of worldview (EKMA). The model provides two viewpoints from which to understand the worldview under study. The first viewpoint concentrates on understanding the worldview’s belief structure and the content of those beliefs. The second viewpoint examines …

Self-Directed Learning as a Practice of Workplace Learning: Interpretative Repertoires of Self-Directed Learning in ICT Work

2019

Changing technologies and competition in the field of information and communication technology (ICT) are challenging the learning of individual workers and teams alongside and through work. Organisations call for employees’ autonomy and self-directedness executed by agile operations and low hierarchies, where learning is also increasingly the responsibility of the individuals and teams themselves and occurs in practice without strong control of the organisation. Therefore, the multidimensional concept of self-directed learning becomes essential in the context of learning at work. In this study, we examine how employees in the ICT sector describe self-directed learning practices in the conte…