Search results for "RESPIRATORY SYSTEM"

showing 10 items of 1829 documents

<p>Early management of COPD: where are we now and where do we go from here? A Delphi consensus project</p>

2019

Purpose There is a lack of consensus on the most appropriate early diagnostic strategy, criteria for early access to treatment and follow-up approach for patients with COPD. Materials and methods A Delphi consensus project investigated the early management of COPD. We formulated two questionnaires for completion by pneumologists in Italy. Results A total of 207 specialists completed questionnaire 1 and 184 of them questionnaire 2, between November 2016 and October 2017. Early diagnosis of COPD was considered uncommon for 93.2% of the expert panel. Regardless of the definition of "early diagnosis" - a diagnosis made before the clinical manifestation of the disease for most responders (60.4%)…

COPDmedicine.medical_specialtybiologybusiness.industrymedicine.medical_treatmentDelphi methodGeneral MedicineDiseaseEvidence-based medicineLamamedicine.diseasebiology.organism_classificationNatural history03 medical and health sciences0302 clinical medicine030228 respiratory systemmedicineSmoking cessation030212 general & internal medicineIntensive care medicinebusinessHealth policyInternational Journal of Chronic Obstructive Pulmonary Disease
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Dual bronchodilation vs triple therapy in the “real-life” COPD DACCORD study

2018

Roland Buhl,1 Carl-Peter Criée,2 Peter Kardos,3 Claus F Vogelmeier,4 Konstantinos Kostikas,5 Nadine S Lossi,6 Heinrich Worth7 1Pulmonary Department, Mainz University Hospital, Mainz, 2Department of Sleep and Respiratory Medicine, Evangelical Hospital Goettingen-Weende, Bovenden, 3Group Practice and Centre for Allergy, Respiratory and Sleep Medicine, Red Cross Maingau Hospital, Frankfurt am Main, 4Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University Marburg, Member of the German Center for Lung Research (DZL), Marburg, Germany; 5WorldWide Medical Affairs Respiratory, Novartis Pharma AG, Basel, Switzerland;…

COPDmedicine.medical_specialtybusiness.industrymedicine.drug_classGeneral MedicineInternational Journal of Chronic Obstructive Pulmonary Diseasemedicine.diseaseClinical trial03 medical and health sciences0302 clinical medicinePrior Therapy030228 respiratory systemMaintenance therapyBronchodilatorInternal medicineCohortMedicineCorticosteroidObservational study030212 general & internal medicinebusinessInternational Journal of Chronic Obstructive Pulmonary Disease
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HRCT evaluation of bronchial response to deep inspiration in asthma and chronic obstructive pulmonary disease (COPD)

2012

Purpose Methods and Materials Results Conclusion References Personal Information

CT-High ResolutionComputer Applications-Detection diagnosisChronic obstructive airways diseaseHRCT ASTHMACOPDSettore MED/10 - Malattie Dell'Apparato RespiratorioThoraxLungRespiratory system
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Pulmonary functional and radiological correlations of nutritional status and physical activity in systemic sclerosis

2011

Purpose Methods and Materials Results Conclusion References Personal Information

CT-High ResolutionConnective tissue disordersPulmonary Function Radiology Nutritional status Physical Activity Systemic SclerosisSettore MED/10 - Malattie Dell'Apparato RespiratorioRespiratory system
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Utility of serum procalcitonin and C-reactive protein in severity assessment of community-acquired pneumonia in children

2015

OBJECTIVES: Although the importance of serum Procalcitonin (PCT) levels at diagnosis is well established in adult Community-Acquired Pneumonia (CAP), its use remains controversial in pediatric CAP. The aim of our study is to investigate the role of PCT and C-Reactive Protein (CRP) in the assessment of pediatric CAP severity defined by the extent of consolidation on chest X-rays and the presence of pleural effusion. In this particular setting, no clinical severity score is available at present and chest X-ray, although important for diagnosis confirmation, is not recommended as routine test. DESIGN AND METHODS: The study involved 119 children admitted to the Department of Pediatric Infectiou…

CalcitoninMalemedicine.medical_specialtyLobar consolidationAdolescentPleural effusionCalcitonin Gene-Related PeptideClinical BiochemistryDiseaseSeverity of Illness IndexSeverityProcalcitonin03 medical and health sciences0302 clinical medicineCommunity-acquired pneumoniaInternal medicineparasitic diseasesSeverity of illnessPneumonia BacterialmedicineHumans030212 general & internal medicineProtein PrecursorsChildIntensive care medicinebookbiologybusiness.industryC-reactive proteinInfantGeneral Medicinemedicine.diseasePleural effusionCommunity-Acquired InfectionsPneumoniaSettore BIO/12 - Biochimica Clinica E Biologia Molecolare ClinicaC-Reactive ProteinPediatric community-acquired pneumonia030228 respiratory systemChild PreschoolPediatric Infectious Diseasebiology.proteinbook.journalPneumococcalFemaleCRPbusinessProcalcitoninhormones hormone substitutes and hormone antagonistsClinical Biochemistry
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Oral microbiome in Proliferative Verrucous Leukoplakia exhibits loss of diversity and enrichment of pathogens.

2021

Abstract Objectives Oral microbiome plays an important role in oral diseases. Among them, proliferative verrucous leucoplakia (PVL) is an uncommon form of progressive multifocal leukoplakia with a worryingly rate of malignant transformation. Here, we aimed to characterize the oral microbiome of PVL patients and compare it with those of healthy controls. Material and methods Oral biopsies from ten PVL patients and five healthy individuals were obtained and used to compare their microbial communities. The sequence of the V3-V4 region of 16S rRNA gene was used as the taxonomic basis to estimate and analyze the composition and diversity of bacterial populations present in the samples. Results O…

Cancer ResearchBiopsymedicine.disease_causeCampylobacter jejuniRNA Ribosomal 16SmedicineProliferative verrucous leukoplakiaHumansEubacteriumLeukoplakiaMouthbiologyCampylobacterMicrobiotabiochemical phenomena metabolism and nutritionrespiratory systembacterial infections and mycosesbiology.organism_classificationmedicine.disease16S ribosomal RNAstomatognathic diseasesCell Transformation NeoplasticOncologyImmunologyOral MicrobiomeOral SurgeryLeukoplakia OralDysbiosisOral oncology
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Different patterns of cytokeratin expression in the normal epithelia of the upper respiratory tract

1985

The distribution and type of cytokeratins present in the normal human epithelia of the nasopharynx, oropharynx, tongue, palatine tonsil, epiglottis, vocal cord, and laryngeal ventricle were studied using immunohistochemical techniques and by gel electrophoresis of cytoskeletal proteins microdissected from frozen tissues. Noncornifying stratified epithelia covering the oropharynx, tongue, surface of the palatine tonsil, pharyngeal surface of the epiglottis, and vocal cord were all found to contain cytokeratins nos. 4, 5, 6, 13, 14, and 15, together with minor amounts of cytokeratin no. 19, i.e., a pattern similar to that previously reported for esophageal epithelium. The immunohistochemical …

Cancer ResearchEpiglottisRespiratory SystemLaryngeal VentricleFluorescent Antibody TechniqueOropharynxStratified squamous epitheliumColumnar CellBiologyEpitheliumPalatine tonsilCytokeratinTongueTongueNasopharynxmedicineHumansMolecular BiologyStaining and LabelingAntibodies MonoclonalCell BiologyAnatomyRespiratory Tract Neoplasmsmedicine.anatomical_structureKeratinsElectrophoresis Polyacrylamide GelLarynxPseudostratified columnar epitheliumDevelopmental BiologyDifferentiation
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A single-Institution retrospective analysis of metastatic bronchial carcinoids with a focus on recurrence pattern.

2016

e20586Background: Bronchial carcinoids (BCs) are rare, usually slow-growing malignancies that develop from diffuse neuroendocrine cells in the lungs and airways. Their prognosis is good when they a...

Cancer ResearchFocus (computing)medicine.medical_specialtyOncologybusiness.industryRetrospective analysisMedicineRadiologyrespiratory systemSingle institutionbusinessrespiratory tract diseasesJournal of Clinical Oncology
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New generation of cancer stem cells inhibitors in non-small cell lung cancer.

2018

e20545Background: Lung cancer is the commonest tumor worldwide of which the most frequent type is non-small cell lung cancer (NSCLC) that represents a large proportion of cancer deaths and is chara...

Cancer ResearchOncologyCancer stem cellbusiness.industrymedicineCancer researchCancerNon small cellrespiratory systemLung cancermedicine.diseasebusinessrespiratory tract diseasesJournal of Clinical Oncology
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Interstitial lung disease in patients with non-small-cell lung cancer: causes, mechanisms and management

2004

Interstitial lung disease in patients with non-small-cell lung cancer: causes, mechanisms and management

Cancer ResearchPathologymedicine.medical_specialtyIntroductionLung Neoplasmsbusiness.industryInterstitial lung diseaserespiratory systemmedicine.diseaserespiratory tract diseasesText miningOncologyCarcinoma Non-Small-Cell LungmedicineHumansIn patientNon small cellbusinessLung cancerLung Diseases InterstitialBritish Journal of Cancer
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