Search results for "RETINA"

Qualiment: the scientifist expertise to promote innovation in food companies

2011

Prevalence of dry eye disease in elderly individuals of the French population (the MONTRACHET Study)

2013

Purpose To report the prevalence of dry eye in a large population-based sample of French individuals older than 75 years. Methods About 9000 individuals 65 years and older were included in the 3C cohort study since 1999 in 3 French cities (Bordeaux, Dijon and Montpellier). In Dijon, an additional ophthalmic examination was performed 10 years after the initial inclusions to assess the relation between systemic age-related diseases and eye diseases in the MONTRACHET Study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases). Dry eye symptoms were collected with self reported history of dry eye symptoms, use of topical medications and evaluated by the Ocular Surface Disease Ind…

Anatomical and functional macular changes after rhegmatogenous retinal detachment with macula off

2011

International audience; Purpose: To evaluate the correlation between morphologic changes in the outer retina and visual function after successful repair of rhegmatogenous retinal detachment with macula off. Methods: Thirty patients (30 eyes) with successful repair of rhegmatogenous retinal detachment (RD) after macula off and a minimum 6-month follow-up after the surgery were examined. Preoperative characteristics of the RD (visual acuity and duration) were collected. Postoperative visual acuity measurement with ETDRS scale and fundus autofluorescence (FAF) were performed. Spectral-Domain Optical Coherence Tomography (HRA OCT) of outer retina was performed to analyse the number of disrupted…

Is Saffron Able to Prevent the Dysregulation of Retinal Cytokines Induced by Ocular Hypertension in Mice?

2021

Cytokine- and chemokine-mediated signalling is involved in the neuroinflammatory process that leads to retinal ganglion cell (RGC) damage in glaucoma. Substances with anti-inflammatory properties could decrease these cytokines and chemokines and thus prevent RGC death. The authors of this study analysed the anti-inflammatory effect of a hydrophilic saffron extract standardized to 3% crocin content, focusing on the regulation of cytokine and chemokine production, in a mouse model of unilateral laser-induced ocular hypertension (OHT). We demonstrated that following saffron treatment, most of the concentration of proinflammatory cytokines (IL-1β, IFN-γ, TNF-α, and IL-17), anti-inflammatory cyt…

Plasmalogens and cell-cell communication between retinal glial cells

2016

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.; Purpose: Plasmalogens (or ether-lipids) are a particular class of glycerophospholipids characterized by the presence of a vinyl-ether bond at the sn-1 position of the glycerol backbone and by the preferential esterification of polyunsaturated fatty acids (PUFAs) at the sn-2 position. Plasmalogens are found at high concentrations in retinal macroglial cells such as Müller cells and astrocytes. Müller cells and astrocytes are known to communicate by the way of intracellular calcium waves and gap junctions. Connexin 43 is the major protein of these communicating junctions. The aim o…

Contributions à l'analyse et à l'interprétation des images : Extraction et représentation de caractéristiques

2016

Ce mémoire, rédigé en vue de l'obtention de l'Habilitation à Diriger des Recherches (HDR), offre un aperçu des travaux de recherche et d’encadrement que j’ai pu mener depuis l'obtention de mon doctorat. Il montre la diversité des champs d’application et de recherche (en vision et en imagerie médicale) que j’ai pu couvrir , ainsi que mon implication dans l’encadrement doctoral.Mes activités de recherche se divisent en deux grandes parties. D'une part, l'analyse de scènes dynamiques, à savoir la détection de regions d'intérêt dans des séquences d'images, pour réduire la taile des données à traiter, et la détection et le suivi d'objets mobiles à l'aide de caméras de diverses natures (perspecti…

Automated Detection of Microaneurysms Using Scale-Adapted Blob Analysis and Semi-Supervised Learning

2014

International audience; Despite several attempts, automated detection of microaneurysm (MA) from digital fundus images still remains to be an open issue. This is due to the subtle nature of MAs against the surrounding tissues. In this paper, the microaneurysm detection problem is modeled as finding interest regions or blobs from an image and an automatic local-scale selection technique is presented. Several scale-adapted region descriptors are then introduced to characterize these blob regions. A semi-supervised based learning approach, which requires few manually annotated learning examples, is also proposed to train a classifier to detect true MAs. The developed system is built using only…

Flash visual evoked potentials: maturation from birth to 15 years of age

2011

Flash visual evoked potentials: maturation from birth to 15 years of age. annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO)

The effect of blue-light-blocking lenses on retinal straylight

2021

Sometimes yellow-tinted lenses are recommended to help improve visual quality. As yellow lenses filter blue light, it is believed that their use could decrease the intensity of scattered light in the eye (retinal straylight). However, the results of some studies have contradicted this assumption (Van Os et al. 2017). Currently various nontinted blue-light-blocking lenses are used to protect the eyes from short-wavelength light. The objective of this study was to determine whether blue-light-blocking lenses affect the levels of retinal straylight in the eye. A straylight meter (C-Quant, Oculus) was used for retinal straylight measurements. The measurements were performed under four different…

Optical quality of hyperopic and myopic phakic intraocular lenses

2013

Aims: To assess and compare the optical quality of the myopic and hyperopic implantable collamer lens (ICL) from its wavefront aberrations for different powers and pupil diameters. Settings and Design: Prospective study. Material and Methods: The wavefront aberrations of two myopic (−3 and −6 diopters (D)) and two hyperopic V4b ICLs (+3 and +6D) were measured in vitro . To assess and compare the optical quality of different powers of ICLs, we analyzed the root mean square (RMS) of total higher order aberrations (HOAs), trefoil, coma, tetrafoil, secondary astigmatism, and spherical aberration at 3- and 4.5-mm pupil. In addition, the point spread functions (PSFs) of each ICL evaluated were ca…