Search results for "RETROSPECTIVE ANALYSIS"

showing 10 items of 86 documents

Hepatocellular carcinoma in Child's A cirrhosis: a retrospective analysis of matched pairs following liver transplantation vs. liver resection accord…

2013

This is the first matched pair analysis on the puzzling clinical problem of whether to perform liver transplantation (LT) or liver resection (LR) for Child's A hepatocellular carcinoma (HCC) patients. A total of 201 patients diagnosed with HCC and Child's A liver cirrhosis were treated with LT transarterial chemoembolization (TACE) or LR between 1998 and 2012. To achieve the most accurate study design, two groups of 57 patients were matched retrospectively according to their tumor characteristics detected by the initial computerized tomography (CT) scan. Sixteen of 57 LT candidates were not transplanted due to tumor progress during pre-treatment (TACE). Nevertheless, the retrospective analy…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisCarcinoma Hepatocellularmedicine.medical_treatmentMatched-Pair AnalysisMilan criteriaLiver transplantationGastroenterologyResectionRecurrenceInternal medicinemedicineRetrospective analysisHepatectomyHumansIn patientAgedRetrospective StudiesAged 80 and overTransplantationIntention-to-treat analysisbusiness.industryLiver NeoplasmsMiddle Agedmedicine.diseasePrognosisIntention to Treat AnalysisLiver TransplantationSurvival RateHepatocellular carcinomaFemalebusinessFollow-Up StudiesClinical transplantation
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Assessment of EVAR Complications using CIRSE Complication Classification System in the UK Tertiary Referral Centre: A ∼6-Year Retrospective Analysis …

2021

Purpose: To retrospectively analyse complications in endovascular aortic repair (EVAR) interventions and evaluate if the CIRSE (Cardiovascular and Interventional Radiological Society of Europe) complication classification system is appropriate as a standardized classification tool for EVAR patients. Materials and Methods: Demographic, procedural and complication data in 719 consecutive patients undergoing EVAR at one institution from January 2014 to October 2019 were retrospectively reviewed. Data (imaging reports, procedural reports, nurse notes, discharge summary reports) were collected consulting the electronic patient record system (EPR) of the hospital and cleaned and stored in a Micro…

AdultMaleAccess-site complicationmedicine.medical_specialtyTime FactorsAdditional treatmentEndoleakEndovascular aortic repair (EVAR)Tertiary referral centreComplication grading scalePopulationVascular accessRadiology InterventionalSeverity of Illness Index030218 nuclear medicine & medical imagingTertiary Care Centers03 medical and health sciencesYoung Adult0302 clinical medicinePostoperative ComplicationsmedicineRetrospective analysisHumansRadiology Nuclear Medicine and imagingIn patienteducationReferral and ConsultationSocieties MedicalAgedRetrospective StudiesAged 80 and overeducation.field_of_studyCIRSE complication classification systemmedicine.diagnostic_testbusiness.industryGeneral surgeryEndovascular ProceduresInterventional radiologyMiddle AgedUnited KingdomAortic AneurysmEuropeReporting systemTreatment OutcomeRadiological weaponFemaleCardiology and Cardiovascular MedicineComplicationbusinessCardiovascular and interventional radiology
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Dental anomalies inside the cleft region in individuals with nonsyndromic cleft lip with or without cleft palate

2015

Background Individuals with non syndromic cleft lip with or without cleft palate (NSCL±P) present high frequency of dental anomalies, which may represent complicating factors for dental treatment. The aim of this study was to investigate the prevalence of dental anomalies inside cleft area in a group of Brazilians with NSCL±P. Material and Methods Retrospective analysis of 178 panoramic radiographs of patients aged from 12 to 45 years old and without history of tooth extraction or orthodontic treatment was performed. Association between cleft type and the prevalence of dental anomalies was assessed by chi-square test with a significance level set at p≤ 0.05. Results Dental anomalies were fo…

AdultMaleAdolescentCross-sectional studyCleft LipDentistryOdontologíaYoung Adult03 medical and health sciences0302 clinical medicinestomatognathic systemStatistical significancePrevalenceMicrodontiamedicineRetrospective analysisHumansChild030223 otorhinolaryngologyGeneral DentistryRetrospective StudiesOrthodonticsDental anomaliesOral Medicine and PathologyTooth Abnormalitiesbusiness.industryResearchRetrospective cohort study030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludUnilateral complete cleft lipstomatognathic diseasesCross-Sectional StudiesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASFemaleSurgeryTooth agenesisbusiness
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Surgery-triggered and non surgery-triggered Bisphosphonate-related Osteonecrosis of the Jaws (BRONJ): A retrospective analysis of 567 cases in an Ita…

2011

Invasive local procedures are often reported in clinical history of patients suffering from Bisphosphonates-Related Osteonecrosis of the Jaws (BRONJ) but over 40% of spontaneous forms have been also described in literature. We compared age, gender, underlying bone disorders, bisphosphonate therapy, clinical features and surgical outcome of 205 cases (36.2%) of BRONJ non surgery-triggered (group 1) with 362 (63.8%) cases of surgery-triggered forms (group 2). Differences between group 1 and 2 were analysed using Mann-Whitney U and χ2 tests. Statistical analysis was performed using STATA 8. Zoledronate was the most used type of bisphosphonate (63.4% versus 69.0%) and the mandible was the most …

AdultMaleCancer Researchmedicine.medical_specialtyTooth extractionmedicine.medical_treatmentZoledronic AcidSettore MED/28 - Malattie OdontostomatologicheRisk FactorsClinical historySpontaneous formmedicineRetrospective analysisHumansStatistical analysisStage (cooking)AgedRetrospective StudiesAged 80 and overSurgical outcomeBone Density Conservation AgentsDiphosphonatesBRONJOrthognathic Surgical Proceduresbusiness.industryImidazolesOsteonecrosisBisphosphonates-related Osteonecrosis of the JawMiddle AgedBisphosphonateSurgeryZoledronic acidItalyOncologyMulticenter studyFemaleBisphosphonate therapyOral SurgerybusinessJaw Diseasesmedicine.drugOral Oncology
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Clinical and esthetic outcome with immediate insertion and provisionalization with or without connective tissue grafting in presence of mucogingival …

2017

Background Recessions following immediate implant insertion are frequently reported in the literature. Data regarding implant installation in presence of mucogingival recessions are rare. Purpose This study observes soft tissue level changes following immediate implant insertion and provisionalization of implants with or without connective tissue grafts in the anterior maxilla in patients with initial mucogingival recession within a follow-up period between one and eight years. Materials and methods Twenty-six patients with marginal gingival recessions, which were designated for extraction and immediate implant insertion in the anterior zone of the maxilla (13-23), were included. Out of a l…

AdultMaleImmediate Dental Implant LoadingFacial boneGingivaDentistryConnective tissueEsthetics DentalTransplantation AutologousYoung Adult03 medical and health sciencesDental Implants Single-Tooth0302 clinical medicineGermanyMaxillaRetrospective analysisHumansPeriodontal PocketMedicineGingival RecessionGeneral DentistryAgedRetrospective StudiesDental ImplantsBone Transplantationbusiness.industrySoft tissue030206 dentistrySingle toothCone-Beam Computed TomographyMiddle AgedAutologous boneIncisorTreatment Outcomemedicine.anatomical_structureDental Prosthesis DesignConnective Tissue030220 oncology & carcinogenesisMaxillaTooth ExtractionFemaleDental Prosthesis Implant-SupportedImplantOral SurgerybusinessFollow-Up StudiesClinical Implant Dentistry and Related Research
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Retrospective analysis of survival rates and marginal bone loss on short implants in the mandible

2011

Objectives: Short implants have become an interesting alternative to bone augmentation in dental implantology. Design of shorter implants and longer surveillance times are a current research issue. The goal of this study was to show the survival rates of short implants below 9 mm in the partly edentulous mandibular premolar and molar regions with fixed prosthetics. Marginal vertical and 2D bone loss was evaluated additionally. Different implant designs are orientationally evaluated. Material and Methods: A total of 247 dental implants with fixed prosthetics (crowns and bridges) in the premolar and molar region of the mandible were evaluated; 47 implants were 9 mm or shorter. Patient data we…

AdultMaleMolarAdolescentAlveolar Bone LossDentistryStatistics NonparametricRadiography PanoramicRetrospective analysisPremolarHumansMedicineDental Restoration FailureSurvival rateAgedRetrospective StudiesAged 80 and overDental ImplantsOrthodonticsbusiness.industryJaw Edentulous PartiallyDental prosthesisMandibleMiddle AgedSurvival RateShort implantsTreatment Outcomemedicine.anatomical_structureDental Prosthesis DesignFemaleDental Prosthesis Implant-SupportedImplantOral SurgerybusinessClinical Oral Implants Research
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Lack of efficacy of mitoxantrone in primary progressive Multiple Sclerosis irrespective of pharmacogenetic factors: A multi-center, retrospective ana…

2014

Abstract Background Mitoxantrone is used on an off-label basis in primary progressive MS (PPMS). ABC -transporter-genotypes are associated with therapeutic response in relapsing/secondary progressive MS (RP/SPMS). Objective To evaluate potential pharmacogenetic response markers for mitoxantrone in PPMS. Methods 41 mitoxantrone-treated PPMS-patients, 155 mitoxantrone-treated RP/SPMS-patients and 43 PPMS-controls were retrospectively assessed for clinical therapy-response and in correlation with four single-nucleotide-polymorphisms in ABCB1 - and ABCG2 -genes. Results 53.7% PPMS-patients were mitoxantrone-responders, in comparison to 78.1% of RP/SPMS-patients (p = 0.039). There was no associa…

AdultMaleOncologymedicine.medical_specialtyTreatment responseATP Binding Cassette Transporter Subfamily Bmedicine.medical_treatmentImmunologyPrimary Progressive Multiple SclerosisPharmacologyInternal medicineGenotypeLack of efficacymedicineRetrospective analysisATP Binding Cassette Transporter Subfamily G Member 2HumansImmunology and AllergyRetrospective StudiesAnalgesicsMitoxantronebusiness.industryImmunosuppressionMiddle AgedMultiple Sclerosis Chronic ProgressiveNeoplasm Proteins3. Good healthNeurologyPharmacogeneticsATP-Binding Cassette TransportersFemaleNeurology (clinical)MitoxantronebusinessPharmacogeneticsmedicine.drugJournal of Neuroimmunology
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The use of ketamine in a palliative-supportive care unit: a retrospective analysis.

2018

Background: To assess the response to ketamine in patients with difficult pain syndromes. Methods: The charts of patients with uncontrolled pain despite opioid dose escalation of at least two opioids or a combination of them, selected for a burst of ketamine and midazolam were reviewed. One hundred mg/day of ketamine and midazolam 15 mg/day by a continuous intravenous infusion for about 48 hours was offered to patients. Results: Forty-four patients received a burst of ketamine. Ten patients did not achieve any improvement. Pain intensity decreased from a mean of 7.8 (SD, 1.6) to 2.8 (SD, 1.3) (P<0.0005). The outcome was considered optimal, good, and mild in 24, 9, and 1 patients, respective…

AdultMalePalliative careMidazolamAdverse effect03 medical and health sciences0302 clinical medicineRetrospective analysisMedicineHumansPain ManagementKetamine030212 general & internal medicineAdverse effectRefractory painAgedRetrospective StudiesAdvanced and Specialized NursingAged 80 and overbusiness.industryPalliative CareRetrospective cohort studyCancer PainMiddle AgedAnalgesics OpioidAnesthesiology and Pain MedicineOpioidChemotherapy AdjuvantAnesthesiaMidazolamFemaleKetaminebusinessCancer pain030217 neurology & neurosurgerymedicine.drugAnnals of palliative medicine
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Pattern of symptoms and symptomatic treatment in adults and the aged population: a retrospective analysis of advanced cancer patients followed at hom…

2016

Context Data regarding symptom burden and symptomatic drugs in palliative population in different classes of age are lacking. Objective The aim of this retrospective study was to assess the symptom burden, and the profile of symptomatic drugs in the last four weeks of life in adults and older cancer patients followed at home. Methods Charts of 412 patients were retrospectively analyzed by using a backward analysis. Patients were divided into three groups: adults (<65 years, A), old (65-74 years, O1), very old (75-84 years, O2), and the oldest (≥85 years, O3). Results At -4W Karnofsky status was significantly lower for older people (p = 0.03). No significant effect of age on the vector of sy…

AdultMalePediatricsmedicine.medical_specialtyPalliative careNauseaPopulationSymptomatic treatmentPainHome care03 medical and health sciences0302 clinical medicineElderlyAdvanced cancerNeoplasmsRetrospective analysisOld patientsMedicineHumans030212 general & internal medicineAdvanced cancer; Drugs; Elderly; Home care; Old patients; Palliative care; Symptoms; Medicine (all)Karnofsky Performance StatuseducationAgedRetrospective StudiesAged 80 and overeducation.field_of_studybusiness.industryMedicine (all)Anti-Inflammatory Agents Non-SteroidalAge FactorsCancerDrugsRetrospective cohort studyNauseaGeneral MedicineMiddle Agedmedicine.diseaseAdvanced cancerHome Care ServicesAnalgesics Opioid030220 oncology & carcinogenesisSymptomsPalliative careAntiemeticsFemalemedicine.symptombusinessCurrent medical research and opinion
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Retrospective Analysis in Lower Limb Reconstruction: Propeller Perforator Flaps versus Free Flaps.

2017

Background Technical advancements and increasing experience in the management of soft tissue defects in lower extremities have led to the evolution of decisional reconstructive algorithms. Both propeller perforator flaps (PPFs) and free flaps (FFs) proved to be useful methods of reconstruction for lower extremities defects, offering alternative reconstructive tools. We present a case series of PPFs and FFs for reconstruction of lower limbs defects, analyzing and comparing treatment and outcomes. Methods Through a retrospective analysis, we report our experience in performing PPFs or FFs for reconstruction of soft tissue defects of the lower extremities, in patients admitted between 2010 an…

AdultMaleReconstructive surgerymedicine.medical_specialtySoft Tissue InjuriesSettore MED/19 - Chirurgia PlasticaFree flap030230 surgeryFree Tissue FlapsLower limblower limb reconstruction03 medical and health sciences0302 clinical medicinemedicineRetrospective analysisHumansIn patientPrimary healingfree flapAgedRetrospective StudiesAged 80 and overbusiness.industrySoft tissueMiddle AgedPlastic Surgery ProceduresSurgerypropeller perforator flapTreatment Outcome030220 oncology & carcinogenesisSurgerybusinessPerforator FlapPerforator flapsLeg InjuriesJournal of reconstructive microsurgery
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