Search results for "RFA"

showing 10 items of 11106 documents

Incidence of cardiovascular events and risk markers in a prospective study of children diagnosed with Marfan syndrome

2018

Little is known about the incidence of cardiovascular events (CVEs) and their associated risk markers in children with Marfan syndrome (MFS).To assess the incidence of CVEs and determine risk markers in a cohort diagnosed with Marfan syndrome during childhood and followed for several years.From a French multicentre nationwide database, 462 patients with MFS diagnosed during childhood were included prospectively. Patients' files were screened for a period of 20 years (1993-2013). CVEs (e.g. death, aortic dissection, cardiac valve or aortic root surgery) were assessed during the prospective follow-up.Median (interquartile range) age at the end of follow-up was 17.2 (11.1-21.3) years. CVEs wer…

AdultMaleMarfan syndromePediatricsmedicine.medical_specialtyTime FactorsAdolescentDatabases Factual030204 cardiovascular system & hematologyRisk AssessmentMarfan SyndromeYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInterquartile rangeCardiac valvemedicineHumansProspective Studies030212 general & internal medicineChildProspective cohort studyAortic dissectionbusiness.industryIncidenceIncidence (epidemiology)Age FactorsInfantGeneral MedicinePrognosismedicine.diseaseConfidence intervalCardiovascular DiseasesChild PreschoolCohortFemaleFranceCardiology and Cardiovascular MedicinebusinessArchives of Cardiovascular Diseases
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An Emerging Method to Assess Tear Film Spread and Dynamics as Possible Tear Film Homeostasis Markers

2021

This study aims to assess the performance of an analysis method to measure in vivo the movement speed of tear film particles post-blink as a measure of tear film spreading. Ocular surface parameter...

AdultMaleMaterials scienceAdolescentgenetic structuresMeasure (physics)Young Adult03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineHomeostasisHumansAnalysis methodAgedAged 80 and overBlinkingDynamics (mechanics)Meibomian GlandsMiddle AgedHealthy Volunteerseye diseasesSensory SystemsOphthalmologyTears030221 ophthalmology & optometryDry Eye SyndromesFemalesense organsOcular surface030217 neurology & neurosurgeryBiomedical engineeringCurrent Eye Research
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Relationship between foot eversion and thermographic foot skin temperature after running.

2017

The main instruments to assess foot eversion have some limitations (especially for field applications), and therefore it is necessary to explore new methods. The objective was to determine the relationship between foot eversion and skin temperature asymmetry of the foot sole (difference between medial and lateral side), using infrared thermography. Twenty-two runners performed a running test lasting 30 min. Skin temperature of the feet soles was measured by infrared thermography before and after running. Foot eversion during running was measured by kinematic analysis. Immediately after running, weak negative correlations were observed between thermal symmetry of the rearfoot and eversion at…

AdultMaleMaterials scienceTime FactorsContact time0206 medical engineeringPlantar surface02 engineering and technologyRunning03 medical and health sciences0302 clinical medicineOpticsFOOT EVERSIONHumansPronationElectrical and Electronic EngineeringEngineering (miscellaneous)Orthodonticsbusiness.industryStance phaseFootSkin temperature030229 sport sciencesLateral side020601 biomedical engineeringAtomic and Molecular Physics and OpticsThermographyThermographyFemalebusinessSkin TemperatureFoot (unit)Applied optics
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Do spinal meningiomas penetrate the pial layer? Correlation between magnetic resonance imaging and microsurgical findings and intracranial tumor inte…

1997

OBJECTIVE: To study the relationships between spinal dura-arachnoid and tumor-cord interfaces in spinal meningiomas and to investigate whether a disruption of the pial layer and penetration of the tumor in the spinal cord occurs. METHODS: Fifteen patients with histologically proven meningiomas underwent magnetic resonance imaging (MRI) preoperatively. All patients underwent microsurgery. The histological characteristics of the tumors were compared with MRI and microsurgical findings. RESULTS: At surgery, the peritumoral hypointense rim revealed by MRI in 10 of 15 patients corresponded to a well-defined cerebrospinal fluid-containing space confined between the outer arachnoidal layer and the…

AdultMaleMicrosurgeryPathologymedicine.medical_specialtyDura materBrain tumorMeningiomaMeningeal NeoplasmsmedicineHumansNeoplasm InvasivenessSpinal Meningesbusiness.industrySettore MED/27 - NeurochirurgiaLeptomeningesSpinal meningiomas tumor interfacesAnatomyMiddle AgedSpinal cordmedicine.diseaseMagnetic Resonance Imagingnervous system diseasesmedicine.anatomical_structureArachnoid materPia MaterFemaleSurgeryNeurology (clinical)ArachnoidSubarachnoid spaceMeningiomabusiness
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A novel minimally invasive, dorsolateral, tubular partial odontoidectomy and autologous bone augmentation to treat dens pseudarthrosis: cadaveric, 3D…

2017

OBJECTIVE The goal of this study was to demonstrate the clinical and technical nuances of a minimally invasive, dorsolateral, tubular approach for partial odontoidectomy, autologous bone augmentation, and temporary C1–2 fixation to treat dens pseudarthrosis. METHODS A cadaveric feasibility study, a 3D virtual reality reconstruction study, and the subsequent application of this approach in 2 clinical cases are reported. Eight procedures were completed in 4 human cadavers. A minimally invasive, dorsolateral, tubular approach for odontoidectomy was performed with the aid of a tubular retraction system, using a posterolateral incision and an oblique approach angle. Fluoroscopy and postprocedur…

AdultMaleModels Anatomicmedicine.medical_specialtyBone ScrewsRadiography Interventional03 medical and health sciencesUser-Computer InterfaceYoung Adult0302 clinical medicineImaging Three-DimensionalCadaverPars interarticularismedicineCadaverFluoroscopyHumansComputer SimulationOrthopedic ProceduresFixation (histology)030222 orthopedicsmedicine.diagnostic_testbusiness.industryGeneral Medicinemedicine.diseaseSurgeryPseudarthrosisPseudarthrosismedicine.anatomical_structureFluoroscopyCervical VertebraeFeasibility StudiesSpinal FracturesOrthopedic ProceduresCadaveric spasmbusinessTomography X-Ray Computed030217 neurology & neurosurgeryCervical vertebraeJournal of neurosurgery. Spine
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Prevalence of Occult Hepatitis B Virus Infection in a Cohort of HIV-Positive Patients Resident in Sicily, Italy

2013

Occult hepatitis B virus (OBI) in HIV-infected groups is still debated, as well as the associated risk-factors and clinical significance. In this paper, we examined a total of 405 HBsAg-negative/HIV-infected patients enrolled from January 2007 to December 2009. Overall, the prevalence of OBI was 5.9% (95% confidence interval (CI95%): 3.8–8.7%); it was more frequently associated with “anti-HBc alone” serological marker (11.3%; adjusted odds ratio = 3.7, CI95%: 1.4–9.8), although it was also detected in the absence of any HBV serological marker (4.9%; CI95%: 2.3–9.1%). A low prevalence of anti-HCV-positive patients with OBI was found (3.1%; CI95%: 0.6–8.7%). HIV RNA plasma levels or other imm…

AdultMaleOccult HBV HIV Prevalence Sicily Italymedicine.medical_specialtyHepatitis B virusArticle Subjectlcsh:MedicineHIV Infectionsmedicine.disease_causeSettore MED/42 - Igiene Generale E ApplicataGeneral Biochemistry Genetics and Molecular BiologySerologyInternal medicineGenotypemedicinePrevalenceHumansClinical significanceSicilyDemographyHepatitis B virusHepatitis B Surface AntigensGeneral Immunology and Microbiologybusiness.industrylcsh:Rvirus diseasesGeneral MedicineOdds ratioHepatitis Bmedicine.diseaseHepatitis BOccultdigestive system diseasesCohortImmunologyClinical StudyFemalebusiness
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The clinical value of tumor burden at diagnosis in Hodgkin lymphoma

2004

BACKGROUND The authors investigated the clinical role of tumor burden (TB) in patients with Hodgkin lymphoma, relating this parameter to most of the current clinical and prognostic factors and to the best predictive multifactorial models. METHODS The volume of TB at diagnosis was measured directly from the initial staging computed tomography scans in 351 patients who were treated on standard protocols. The mean patient age was 34.0 years ± 16.4 years. Forty-six patients had clinical Stage I disease, 201 patients had Stage II disease, 64 patients had Stage III disease, and 40 patients had Stage IV disease. There were 146 symptomatic patients. Overall survival (OS), disease-free survival (DFS…

AdultMaleOncologyCancer Researchmedicine.medical_specialtyTime FactorsMultivariate analysisAdolescentBody Surface AreaDiseaseLogistic regressionText miningPredictive Value of TestsInternal medicineBiomarkers TumormedicineHumansTreatment FailureStage (cooking)Neoplasm StagingRetrospective StudiesBody surface areabusiness.industryRemission InductionCancerMiddle AgedPrognosismedicine.diseaseHodgkin DiseaseSurgeryLymphomaSurvival RateOncologyFemaleTomography X-Ray ComputedbusinessCancer
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Influence of age, gender and obesity on pressure discomfort threshold of the foot: A cross-sectional study

2021

[EN] Background: Foot pain is a highly prevalent health problem for which measures such as a pattern of Pressure Discomfort Threshold of the foot plantar surface can provide valuable information for orthosis design. This study aimed to describe such pattern as a tool for the assessment of painful conditions of the feet and to analyse how it modifies according to age, gender and obesity. Methods: A cross-sectional study was performed with participants allocated in: Group 1 people aged 20 to 35 years, Group 2 aged 50 to 65 years and Group 3 aged over 65. Pressure Discomfort Threshold on twelve points of the foot plantar surface was measured with an adapted manual dynamometer. Inferential anal…

AdultMalePain Thresholdmedicine.medical_specialtyOrthotic DevicesAgingHeelCross-sectional studyBiophysicsPlantar surface03 medical and health sciences0302 clinical medicinePressureMedicineHumansOrthopedics and Sports MedicineObesityBody mass indexAgedSex Characteristicsbusiness.industryFootGender030229 sport sciencesMiddle Agedmedicine.diseaseObesitymedicine.anatomical_structureCross-Sectional StudiesPhysical therapyFemaleAnalysis of variancebusinessBody mass index030217 neurology & neurosurgeryFoot (unit)Discomfort
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CD27 distinguishes two phases in bone marrow infiltration of splenic marginal zone lymphoma.

2004

Aims:  To investigate CD27 expression in splenic marginal zone lymphoma (SMZL), an indolent low-grade B-cell lymphoma with constant involvement of the bone marrow, especially with an intrasinusoidal pattern. It is not clear if the neoplastic clone is composed of virgin or somatically mutated B cells. CD27 is reported to be a hallmark of memory B cells. Methods and results:  We evaluated 64 bone marrow biopsy specimens (BMBs) from 36 patients with SMZL for the expression of CD27. For comparison, splenectomy specimens of patients with traumatic splenic rupture or with SMZL were used. All BMBs showed lymphomatous infiltration. When located in the marrow sinusoids, neoplastic cells were CD27– i…

AdultMalePathologymedicine.medical_specialtyHistologybone marrowLymphomaBiopsyNaive B cellsplenic marginal zone lymphomaSplenic NeoplasmSpleenPathology and Forensic MedicineBiopsyintrasinusoidal infiltrationmedicineHumansSplenic marginal zone lymphomaCD27naive and memory B cellsAgedAged 80 and overmedicine.diagnostic_testbusiness.industrySplenic NeoplasmsGeneral MedicineMiddle Agedmedicine.diseaseBone Marrow NeoplasmImmunohistochemistryTumor Necrosis Factor Receptor Superfamily Member 7bone marrow; CD27; intrasinusoidal infiltration; naive and memory B cells; splenic marginal zone lymphomamedicine.anatomical_structureBone marrow neoplasmFemaleBone marrowbusinessBone Marrow NeoplasmsInfiltration (medical)
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Functional gastrointestinal disorders among soldiers in peacetime versus out-of-area missions.

2001

Functional gastrointestinal syndromes are chronic disorders of the abdomen with an absence of organic findings. The aim of this study was to compare the frequency and symptomatology of functional abdominal syndromes in soldiers during an out-of-area mission versus during peacetime at home. We examined 124 soldiers who sought medical care for abdominal symptoms at the German Field Hospital Trogir, Croatia. The control group consisted of 113 soldiers who were referred with abdominal symptoms to the Central Hospital of German Armed Forces Koblenz, Germany. After excluding an organic disease, the diagnosis of a functional disorder was made. Fourteen percent of the Implementation Force soldiers …

AdultMalePeacetimemedicine.medical_specialtyWarfareAdolescentCroatiaeducationColonic Diseases FunctionalOrganic diseaseHospitals MilitaryFunctional disordermedicineHumansDyspepsiaTravelbusiness.industryIncidence (epidemiology)Public Health Environmental and Occupational HealthCase-control studyGeneral MedicineMiddle Agedmedicine.diseaseChronic disordersSurgeryMilitary personnelmedicine.anatomical_structureMilitary PersonnelCase-Control StudiesPopulation SurveillanceEmergency medicineChronic DiseaseAbdomenbusinessMilitary medicine
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