Search results for "RICH"

showing 10 items of 3360 documents

Drug‐refractory myasthenia gravis: Clinical characteristics, treatments, and outcome

2022

[Objective] To describe the clinical characteristics and outcomes in patients with refractory myasthenia gravis (MG) and to determine the effectiveness and side effects of the drugs used for their treatment.

Maleprogressive multifocal leukoencepdiarrheacholinergic receptorplasma exchangemiddle agedadultimmunologic factornauseaanemiahypertrichosisageddrug withdrawaldiabetes mellitusdisease severityTRIALsafetycorticosteroidhypertensionImmunologyMiastenia gravismethotrexateArticlebulbar paralysispancytopeniaMuscular DiseasescompulsionMyasthenia Gravischolinesterase inhibitorcross-sectional studyHumansImmunologic FactorshumanRITUXIMABarthralgiaNeurologíaMalalties muscularsAgedRetrospective Studiesmyasthenia gravisleukopeniaabdominal painDrug testingmajor clinical studyCross-Sectional StudiesDrug side effectscyclophosphamideobservational studyNeurology (clinical)immunoglobulinFEATURESefficacyclinical outcomeelectrophysiological procedurescomputer assisted tomographyDOUBLE-BLINDTratamiento médicorituximabOutcome Assessment Health CareImmunologiamuscle specific tyrosine kinaseRegistriestacrolimusazathioprineMedicamentoGeneral Neurosciencenephrotoxicitygeneral condition deteriorationhyperplasiatrialMiddle Agedliver toxicitydrug toxicityunclassified drugfemaleEfectes secundaris dels medicamentsSAFETYFemaledouble-blindheadacheblindnessAdultAssaigs clínics de medicamentsmalefeaturesfollow uppneumoniacyclosporinemycophenolate mofetilprotein tyrosine kinaseimmunosuppressive agentallergyalopeciaEFFICACYclinical featureosteopeniaSpainprednisonehyperglycemiaautoantibodyFollow-Up Studies
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The Independent Effects of Psychosocial Stressors on Subclinical Psychosis: Findings from the Multinational EU-GEI Study

2021

The influence of psychosocial stressors on psychosis risk has usually been studied in isolation and after the onset of the disorder, potentially ignoring important confounding relationships or the fact that some stressors that may be the consequence of the disorder rather than preexisting. The study of subclinical psychosis could help to address some of these issues. In this study, we investigated whether there was (i) an association between dimensions of subclinical psychosis and several psychosocial stressors including: childhood trauma, self-reported discrimination experiences, low social capital, and stressful life experiences, and (ii) any evidence of environment-environment (ExE) inte…

Malestressful life eventsSchizotypypositive subclinical symptomEthnic groupSocial Environmentsubclinical psychosispositive subclinical symptoms0302 clinical medicineAdverse Childhood ExperiencesSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.SINTOMAS PSÍQUICOSsubclinical psychosi10. No inequalityCOMMUNITY ASSESSMENTSubclinical infectionGENERAL-POPULATIONpsychotic symptomDepressionConfoundingSocial Discriminationdepressive subclinical symptomstressful life eventETHNIC-GROUPS3. Good healthPsychiatry and Mental healthNEIGHBORHOOD CHARACTERISTICSADULT PSYCHIATRIC-DISORDERSpsychotic symptomsAdverse Childhood ExperienceFemalepsychosocial stressPsychologyPsychosocialHumanClinical psychologynegative subclinical symptompsychosocial streAdultPsychosisSiblingLIFE EVENTSschizotypyPsychotic Disorder03 medical and health sciencesCommunity Assessment of Psychic Experiences (CAPE)THREATENING EXPERIENCESmedicineHumansEuropean UnionSiblingSettore MED/25 - Psichiatriachildhood traumaSiblingsStressormedicine.diseasePERCEIVED DISCRIMINATIONnegative subclinical symptoms030227 psychiatryPSYCHOMETRIC PROPERTIESPsychotic Disorders[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthdis criminationsocial capitaldepressive subclinical symptomsStress Psychological030217 neurology & neurosurgeryRegular Articlesdiscrimination
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Improving operating room efficiency: an observational and multidimensional approach in the San Camillo-Forlanini Hospital, Rome

2017

SCOPO.Le sale operatorie (SOs) sono strutture organizzative caratterizzate da un elevato grado di comples- sità organizzativa e gestionale che pone un attento monitoraggio dei processi produttivi, in una logica “spendingreview”. Pertanto diviene necessario pianificare interventi di miglioramento ove questi siano applicabili. È in questo contesto che è stata realizzata questa indagine, al fine di migliorare l’efficienza del servizio reso a parità di costi METODI. E’ stato realizzato una analisi organizzativa tra i mesi di Aprile e Dicembre 2016 su un blocco operatorio dell’azienda ospedaliera, applicando la metodologia “process management” alla realtà delle SOs. Il progetto ha coinvolto due …

ManagementScienze InfermieristicheSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheSala Operatoria
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Adverse effects of heavy cannabis use: even plants can harm the brain.

2020

The spread of laws legalising cannabis for medicinal or recreational use has been accompanied by more relaxed attitudes towards cannabis. Data from the United States show that in states that have legalised cannabis, prevalence of daily, weekly, and monthly cannabis use was 11.3%, 18.3%, and 25.0% respectively, whereas in countries where it is still illegal, it was lower (7.4%, 11.6%, and 16.8% respectively). Evidence indicates a trend of increase among adolescents, a particular vulnerable category for the initiation of substance use. In parallel, we have seen the concentration of THC (D-9-tetrahydrocannabinol) in the cannabis sold both in the United States and in Europe rising and those typ…

Marijuana AbuseDrug-Related Side Effects and Adverse Reactionsbusiness.industryheavy cannabis useMEDLINEBrainCannabis useAdverse effectAnesthesiology and Pain MedicineHarmNeurologyEnvironmental healthSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.MedicineNeurology (clinical)Topical ReviewbusinessAdverse effectSettore MED/25 - PsichiatriaCannabisPain
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Daily use of high-potency cannabis is associated with more positive symptoms in first-episode psychosis patients: The EU-GEI case-control study

2021

The work was supported by: Clinician Scientist Medical Research Council fellowship (project reference MR/M008436/1) to MDF; the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South London at King’s College Hospital NHS Foundation Trust to DQ; DFG Heisenberg professorship (no. 389624707) to UR. National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and King’s College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. The EU-GEI Project is funded by t…

Marijuana AbuseIMPACTPoison controlCannabis usecannabis-associated psychosis0302 clinical medicineSCHIZOPHRENIASettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.health care economics and organizationsApplied PsychologyRISKOUTCOMESbiologyHuman factors and ergonomics/dk/atira/pure/subjectarea/asjc/2700/2738psychopathologyCannabis use; cannabis-associated psychosis; first episode psychosis; psychopathology; psychotic experiences; symptom dimensions3. Good healthPsychiatry and Mental healthSchizophreniaHEALTHPsychopathologyPsychosismedicine.medical_specialtyDISORDERSeducationsymptom dimensions03 medical and health sciencesInjury preventionfirst episode psychosismedicineHumanspsychotic experiencesPsychiatryABUSESettore MED/25 - PsichiatriaSUBSTANCE USEMETAANALYSISCannabisbusiness.industryCase-control studyOriginal Articlesmedicine.diseasebiology.organism_classification030227 psychiatrypsychotic experiencePsychotic Disordersfirst episode psychosiCase-Control StudiesONSETGene-Environment Interaction/dk/atira/pure/subjectarea/asjc/3200/3202Cannabisbusinesscannabis-associated psychosi030217 neurology & neurosurgery
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Shelled-Molluscs Fauna at Abrolhos Bank (Brazil): Assessment of Both Total Species Richness and the Completed Distribution of Species Frequencies by …

2020

Numerous anthropogenic threats to the exceptionally rich coral-reef ecosystem at Abrolhos Bank (Brazil) arguably require implementing drastic conservation policy and meanwhile, urge for the prior detailed assessment of species richness and the species distribution across the Bank. Due to their unavoidable incompleteness, the already implemented “Rapid Assessment Surveys” at Abrolhos Bank deserve being completed, at least numerically, by implementing an appropriate extrapolation procedure, to avoid serious bias precisely due to ignoring both the number and the frequency distribution of those species still remaining undetected after Rapid Assessment Surveys. Complying with this concern, I rep…

Marine biodiversityGeographygeography.geographical_feature_categoryEcologybusiness.industryFaunaExtrapolationDistribution (economics)Species richnessCoral reefGeneral Agricultural and Biological SciencesbusinessGeneral Biochemistry Genetics and Molecular BiologyAnnual Research & Review in Biology
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The invasive seaweed Asparagopsis taxiformis erodes the habitat structure and biodiversity of native algal forests in the Mediterranean Sea

2021

Abstract Invasive seaweeds are listed among the most relevant threats to marine ecosystems worldwide. Biodiversity hotspots, such as the Mediterranean Sea, are facing multiple invasions and are expected to be severely affected by the introduction of new non-native seaweeds in the near future. In this study, we evaluated the consequences of the shift from the native Ericaria brachycarpa to the invasive Asparagopsis taxiformis habitat on the shallow rocky shores of Favignana Island (Egadi Islands, MPA, Sicily, Italy). We compared algal biomass and species composition and structure of the associated epifaunal assemblages in homogenous and mixed stands of E. brachycarpa and A. taxiformis. The r…

Marine protected areaBiodiversityAquatic ScienceOceanographyRocky shoreEpifauna diversityCystoseira sensu latoMediterranean SeaMarine ecosystemHabitat shiftSicilyEcosystemAlgaBiomass (ecology)biologyPrimary producersEcologyEricaria brachycarpaBiodiversityGeneral MedicineEutrophicationSeaweedbiology.organism_classificationPollutionRocky shoreGeographyHabitatAsparagopsis taxiformisSpecies richness
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High frequency modeling technique for three phase power electronics module

2015

Nowadays, the high integrated power electronics modules (PMs), characterized by high speed, low loss and hard ware miniaturization, represent a new technology that meets the emerging demands of many applications, such us vehicle and home appliance, renewable energy sources in smart grid. The integration process and the high switching speeds increase the PM electromagnetic emissions that can create electromagnetic interference (EMI) with electric/electronic devices near the PMs. For this reason, electromagnetic compatibility (EMC) have to be carefully considered, yet in the design phase, to guarantee the reliability of PM systems. In this paper a method to develop a high frequency (HF) model…

MarketingEngineeringRenewable Energy Sustainability and the Environmentbusiness.industryElectromagnetic compatibilityEnergy Engineering and Power TechnologyPower moduleElectromagnetic interferenceElectromagnetic interferenceStrategy and Management1409 Tourism Leisure and Hospitality ManagementSmart gridEMIHigh frequency modelingPower modulePower electronicsMiniaturizationElectronic engineeringElectromagnetic compatibilityElectronicsbusinessSettore ING-INF/07 - Misure Elettriche E Elettroniche2015 5th International Conference on Electric Utility Deregulation and Restructuring and Power Technologies (DRPT)
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Binding site of different tannins on a human salivary proline-rich protein evidenced by dissociative photoionization tandem mass spectrometry

2015

Abstract The sensation of astringency is thought to originate from the interaction occurring between tannins and the salivary proline-rich proteins (PRPs). Astringency perception can be modified by the structure of tannins. Herein, we study the interactions occurring between the human salivary PRP, IB5, and three model tannins with different structure, epigallocatechin gallate and the procyanidin dimers B2 and B2 3′ O -gallate, using the coupling of mass spectrometry and VUV-synchrotron radiation. The results obtained indicate that the structure of tannins, in particular the degree of polymerization and the galloylation, does not modify the binding site on IB5 involved in the interaction.

Mass spectrometryAstringency[CHIM.ORGA]Chemical Sciences/Organic chemistry[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionOrganic ChemistryGallatePhotoionizationEpigallocatechin gallateDegree of polymerizationMass spectrometryTandem mass spectrometryBiochemistryPro line-rich proteinsBinding sitechemistry.chemical_compoundchemistryProanthocyanidinBiochemistry[ CHIM.ORGA ] Chemical Sciences/Organic chemistryDrug DiscoveryBinding siteTannins[SDV.AEN]Life Sciences [q-bio]/Food and NutritionNon-covalent interaction
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The predictability of helminth community structure in space: a comparison of fish populations from adjacent lakes

2002

Patterns in helminth community structure can suggest that various processes are acting to shape parasite communities into organised, non-random assemblages of species. It is not clear, however, whether a pattern observed in one host population at one time would be observed again at another time, or at the same time in a different but comparable host population. Here, we test the repeatability of parasite community structure in space, and to a lesser extent time, with data on helminth parasites of two fish species, perch Perca fluviatilis and roach Rutilus rutilus, collected in different seasons from four adjacent lakes in Central Finland. Since populations of the same fish species harbour t…

Matched-Pair AnalysisPopulation DynamicsPopulationCyprinidaeFresh WaterHost-Parasite InteractionsHelminthsparasitic diseasesmedicineAnimalseducationEcosystemFinlandPercheducation.field_of_studybiologyEcologyFishesCommunity structureSeasonalitybiology.organism_classificationmedicine.diseaseInfectious DiseasesPercidaePerchesNestednessParasitologySpecies richnessRutilusForecastingInternational Journal for Parasitology
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