Search results for "RICH"

Visiting the King of the World

2009

Apsilankymas pas Pasaulio karalių – tai tema, kuri bent paviršutiniškai supažindina su egzistuojančiais daugiau ar mažiau ezoteriniais pasakojimais, kartais net gana fantastiškais, kuriuose kalbama apie viršžmogiškosiomis galiomis apdovanotas būtybes, gyvenančias, atrodo, žemės gelmėse, Azijos žemių platybėse, Himalajų regione, Mongolijoje ar Tibete. „Pasaulio karalius“ – pavadinimas 1927 m. parašyto veikalo, kurio autorius René Guénonas – prancūzų ezoterikas ir mistikas, gimęs 1886 m. Blois, miręs 1951 m. Kaire. Iš literatūros kūrinių – ir kelionių aprašymų, ir fantastinių romanų – be Jules‘io „Kelionės į žemės centrą“ galima paminėti Ferdinando Ossendowskio knygą „Gyvuliai, žmonės ir diev…

Gustav Mahler. Canti del dolore e del commiato

2002

Nel 1901 Gustav Mahler si accosta per la prima volta alle poesie di Friedrich Rueckert, che utilizza in varie composizioni, ma soprattutto nel ciclo dei "Kindertotenlieder" (Canti funebri per i fanciulli). Il saggio si concentra sulla genesi di questo ciclo liederistico, analizzandone alcuni degli aspetti di maggiore rilievo, anche sul piano del rapporto fra la musica e il testo.

Signal sequences modulate the immunogenic performance of human hepatitis C virus E2 gene

2005

Abstract Envelope protein E2 of human hepatitis C virus (HCV) is an attractive component of a prototype HCV vaccine. Delivered by DNA immunogens, E2 evokes specific immune response of Th1-type, failing to induce either considerable antibody production, or T-helper cell proliferation. We aimed at modulating the immunogenic performance of E2 gene by changing the mode of protein expression in eukaryotic cells. Plasmids were constructed encoding full-length E2 and nonstructural protein 1 (p7) fused to either 13 or 38 C-terminal amino acids (aa) of HCV E1 that contain second hydrophobic segment of E1 stop-transfer signal, or a complete E1 stop-transfer signal with duplicated second hydrophobic s…

Neuropsychological Assessment through NeuroVirtual Reality in OCD patients

2013

Use of virtual reality to explore the decision making in obsessive–compulsive disorder and Parkinson’s disease

2013

Improving structural similarity based virtual screening using background knowledge

2013

Background Virtual screening in the form of similarity rankings is often applied in the early drug discovery process to rank and prioritize compounds from a database. This similarity ranking can be achieved with structural similarity measures. However, their general nature can lead to insufficient performance in some application cases. In this paper, we provide a link between ranking-based virtual screening and fragment-based data mining methods. The inclusion of binding-relevant background knowledge into a structural similarity measure improves the quality of the similarity rankings. This background knowledge in the form of binding relevant substructures can either be derived by hand selec…

Summer phytoplankton assemblages across trophic gradients in hard-water reservoirs

1998

Summer phytoplankton assemblages are described and characterised according to their prevalence in a series of hard-water reservoirs of eastern Spain that had been classified in trophic categories on OECD criteria. Distribution patterns of phytoplankton species were ordinated statistically by principal components analysis (PCA). The first component was strongly related to trophic gradient and it particularly discriminated the eutrophic and hypertrophic reservoirs. The second component segregated life-forms, so that (1), on the oligo-mesotrophic side, large dinoflagellates were separated from small centric diatoms, unicellular chrysophytes and filamentous ullotrichales and, on the eu-hypertro…

Bach fra le stelle

2014

Il testo costituisce la postfazione del volume di Ramin Bahrami "Il suono dell'Occidente. Le opere musicali che hanno fatto la nostra civiltà" (Mondadori 2014) e prende le mosse dal concetto di "Enciclopedia" per tracciare una riflessione storico-musicologica sulle 14 composizioni che Ramin Bahrami ssume quali imprescindibili punti di riferimento per una visione d'insieme della cultura musicale occidentale: da Monteverdi fino a Schoenberg, passando per Vivaldi, Bach, Wagner, Verdi, Mahler, Rakhmaninov e Stravnsky.

Lieder und Elegieen

1801

Biogrāfiskā apcerējuma autors: Friebe, Wilhelm Christian,1762-1811

Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein–Coupled Receptor OGR1 (GPR68)

2016

Background & Aims: A novel family of proton-sensing G-proteinâcoupled receptors, including ovarian cancer G-proteinâcoupled receptor 1 (OGR1) (GPR68) has been identified to play a role in pH homeostasis. Hypoxia is known to change tissue pH as a result of anaerobic glucose metabolism through the stabilization of hypoxia-inducible factor-1α. We investigated how hypoxia regulates the expression of OGR1 in the intestinal mucosa and associated cells. Methods: OGR1 expression in murine tumors, human colonic tissue, and myeloid cells was determined by quantitative reverse-transcription polymerase chain reaction. The influence of hypoxia on OGR1 expression was studied in monocytes/macrophages and…