Search results for "RICS"

showing 10 items of 14086 documents

Anti-senescence and Anti-inflammatory Effects of the C-terminal Moiety of PTHrP Peptides in OA Osteoblasts.

2016

Osteoarthritis (OA) is characterized by degenerative changes in the whole joint leading to physical disability in the elderly population. This condition is associated with altered bone metabolism in subchondral areas suggesting that therapeutic strategies aimed at modifying bone cell metabolism may be of interest. We have investigated the effects of several parathyroid hormone-related protein (PTHrP)-derived peptides (1-37): (N-terminal), (107-111) and (107-139) (C-terminal) on senescence features induced by inflammatory stress in human OA osteoblasts. Incubation of these primary cells with interleukin(IL)-1β led to an increased expression of senescence markers senescence-associated-β-galac…

musculoskeletal diseases0301 basic medicineSenescenceMaleAgingmedicine.medical_specialtyInterleukin-1betaParathyroid hormoneFluorescent Antibody TechniqueReal-Time Polymerase Chain ReactionDinoprostone03 medical and health sciencesDownregulation and upregulationInternal medicineBone cellOsteoarthritismedicineHumansProstaglandin E2Cells CulturedCellular SenescenceAgedOsteoblastsParathyroid hormone-related proteinbusiness.industryInterleukin-6Tumor Necrosis Factor-alphaParathyroid Hormone-Related ProteinPeptide Fragments030104 developmental biologyEndocrinologyTumor necrosis factor alphaFemaleGeriatrics and GerontologyInflammation MediatorsbusinessCell aginghormones hormone substitutes and hormone antagonistsmedicine.drugThe journals of gerontology. Series A, Biological sciences and medical sciences
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In-Vitro-Effects of TNF-A and IL-1-Antagonists on the Cytokine Network of Patients with Oligoarticular Idiopathic Arthritis (OJIA)

2011

In-Vitro-Effects of TNF-A and IL-1-Antagonists on the Cytokine Network of Patients with Oligoarticular Idiopathic Arthritis (OJIA)

musculoskeletal diseasesCytokine Networkbusiness.industryPediatrics Perinatology and Child HealthImmunologymedicineArthritisTumor necrosis factor alphaskin and connective tissue diseasesmedicine.diseasebusinessIn vitroPediatric Research
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Fertility in McCune Albright syndrome female: A case study focusing on AMH as a marker of ovarian dysfunction and a literature review.

2021

Abstract Background The molecular basis of McCune Albright syndrome (MAS) is a recurrent GNAS Postzygotic gain of function sporadic mutation, resulting in a mosaic disease. Most of girls present precocious puberty, caused by the development of recurrent ovarian cysts with autonomous Hyperestrogenic stimulation. After menarche, the majority of patients with ovarian GNAS mutation have menstrual disturbances and infertility. Objectives We wanted to focus on the fertility of MAS females and propose an appropriate management, by a detailed case report and an exhaustive review of the literature on fertility and pregnancy in MAS females. Results We present the case of a 29-year-old MAS female, who…

musculoskeletal diseasesInfertilityAdultAnti-Mullerian Hormoneendocrine systemmedicine.medical_specialtyendocrine system diseasesGenetic counselingmedicine.medical_treatmentOvariectomyFertilization in VitroFibrous Dysplasia PolyostoticMcCune–Albright syndrome03 medical and health sciences0302 clinical medicineFollicular phasemedicineGNAS complex locusPrecocious pubertyHumansGynecology030219 obstetrics & reproductive medicineIn vitro fertilisationbiologybusiness.industryObstetrics and GynecologyOophorectomymedicine.diseasefemale genital diseases and pregnancy complicationsReproductive Medicine030220 oncology & carcinogenesisbiology.proteinFemalebusinessInfertility Femalehormones hormone substitutes and hormone antagonistsJournal of gynecology obstetrics and human reproduction
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Stippled epiphyses in fetal alcohol syndrome.

1990

We report on punctate epiphyseal calcifications (stippled epiphyses) in the fetal alcohol syndrome and present the differential diagnosis of chondrodysplasia punctata. A literature survey shows that epiphyseal calcifications accompanying alcoholic embryopathy are regularly located in the lower limbs and rarely found in the upper extremities.

musculoskeletal diseasesMaleChondrodysplasia Punctatabusiness.industryFetal alcohol syndromeInfant NewbornCalcinosisStippled epiphysesAnatomymedicine.diseaseDiagnosis DifferentialRadiographyFetal Alcohol Spectrum DisordersPediatrics Perinatology and Child HealthmedicineHumansRadiology Nuclear Medicine and imagingChondrodysplasia punctataDifferential diagnosisLiterature surveybusinessPediatric radiology
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Transient regional osteoporosis.

2014

Transient regional osteoporosis (TRO) is a disease that predisposes to fragility fracture in weight bearing joints of mid-life women and men. Pregnant women may also suffer the process, usually at the hip. The prevalence of TRO is lower than the systemic form, associated with postmenopause and advanced age, but may be falsely diminished by under-diagnosis. The disease may be uni- or bilateral, and may migrate to distinct joints. One main feature of TRO is spontaneous recovery. Pain and progressive limitation in the functionality of the affected joint(s) are key symptoms. In the case of the form associated with pregnancy, difficulties in diagnosis derive from the relatively young age at pres…

musculoskeletal diseasesMalemedicine.medical_specialtyPediatricsOsteoporosisDiseasemedicine.disease_causeGeneral Biochemistry Genetics and Molecular BiologyWeight-bearingPregnancymedicineHumansPregnancyHip fracturebusiness.industryObstetrics and GynecologyJoint effusionmedicine.diseaseSurgeryOrthopedic surgeryGestationOsteoporosisFemalemedicine.symptomJoint DiseasesbusinessMaturitas
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Analysis of weight gain composition determined in preterm infants with Dual energy x-ray absorptiometry (DXA)

1999

Analysis of weight gain composition determined in preterm infants with Dual energy x-ray absorptiometry (DXA)

musculoskeletal diseasesMaterials scienceDual energymedicine.diagnostic_testmusculoskeletal neural and ocular physiologyAnalytical chemistryComposition (combinatorics)musculoskeletal systemPediatrics Perinatology and Child Healthmedicinemedicine.symptomhuman activitiesWeight gainDual-energy X-ray absorptiometryPediatric Research
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A controlled trial of intra-articular corticosteroids with or without methotrexate in oligoarticular juvenile idiopathic arthritis

2014

In contrast with the numerous controlled trials conducted in polyarticular or systemic juvenile idiopathic arthritis (JIA), little evidence-based information is available for oligoarticular JIA. As a result, the management of children with this subtype, which is the most prevalent in Western countries, is largely empiric. Intra-articular corticosteroid (IAC) injection is the therapy of first choice for oligoarthritis in many pediatric rheumatology centers. However, although IAC injections are usually highly efficacious, relapses of synovitis are common and sometimes occur only a few months after the procedure. It is still unclear whether concomitant administration of methotrexate (MTX) may …

musculoskeletal diseasesPediatricsmedicine.medical_specialtyArthritislaw.inventionSettore MED/38 - Pediatria Generale E SpecialisticaRheumatologyRandomized controlled triallawInternal medicineSynovitismedicineImmunology and AllergyPediatrics Perinatology and Child Healthskin and connective tissue diseasesmethotrexate oligoarticular juvenile idiopathic arthritisOligoarthritisbusiness.industrymedicine.diseaseRheumatologyConcomitantPoster PresentationPediatrics Perinatology and Child HealthMethotrexateOligoarticular Juvenile Idiopathic Arthritisbusinessmedicine.drugPediatric Rheumatology
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The revised ghent nosology; reclassifying isolated ectopia lentis

2014

Inherited ectopia lentis (EL) is most commonly caused by Marfan syndrome (MFS), a multisystemic disorder caused by mutations in FBN1. Historically the diagnosis for patients with EL who have no systemic features of MFS is isolated EL (IEL). However, the Ghent nosology for MFS was updated in 2010 and made some important alterations. In particular, patients with EL and a FBN1 mutation are now categorically diagnosed with MFS, if their mutation has previously been described with aortic dilation/dissection. This carries significant systemic implications, as many patients previously diagnosed with IEL are now reclassified. We provide a review of all published cases of IEL caused by FBN1 mutation…

musculoskeletal diseasesProbandMarfan syndromeNosologycongenital hereditary and neonatal diseases and abnormalitiesPediatricsmedicine.medical_specialtybusiness.industrymedicine.disease3. Good healthDissectionGeneticsMedicineIn patientChinese familyAortic dilationbusinessEctopia lentisGenetics (clinical)Clinical Genetics
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Different sitting positions influence cross country sit skiers performance : Sitting position influence on force generation and cycle characteristics

2018

Cross country sit skiing is a Paralympic discipline in which athletes due to physical impairment ski sitting on a sit-ski. The impairment influences performance directly and also through sitting position. Athletes with a better trunk control usually adopt a sitting position called “kneeing” in which the hip joints are higher than the knee joints. In contrast, athletes with high impact of impairment prefer a sitting position called “knee high” in which the hip joints are lower than the knee joints. Able bodied athletes skiing on the ergometer in these two sitting positions showed different performance. However, to the best of authors’ knowledge, no studies have examined performance, force pr…

musculoskeletal diseasesTrunk controlForce generationmedicine.medical_specialtySittingsitting positionbiomechanics03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineta315paralympialaisetCross countrybiologyAthletesBiomechanicscross country sit skiing030229 sport sciencesmusculoskeletal systemSitting Positionsbiology.organism_classificationvammaisurheiluParalympic sport; Sitting position; Performance; Cross country sit skiing; BiomechanicsPosition (obstetrics)biomekaniikkaparalympic sportPsychologyhuman activities030217 neurology & neurosurgeryperformance
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Acupuncture in the treatment of temporomandibular disorders, facial pain, and postural neuromuscular disorders. Presentation of a clinical case

2021

Abstract Background and objectives Temporomandibular disorders have a multifactorial etiology and involve the masticatory muscles, temporomandibular joint and associated structures. Therefore, different treatments are proposed and used. The aim of this paper is the use of acupuncture to treat temporomandibular disorders and associated symptoms. This article presents a clinical case study of a 39-year-old patient who presented temporomandibular disorders and headache of muscular origin. Results After 10 acupuncture sessions, the results were highly satisfactory, with complete relief of headache pain and absence of joint disorders. These results suggest the efficacy of acupuncture in the symp…

musculoskeletal diseasesmedicine.medical_specialty050402 sociologyPain03 medical and health sciences0302 clinical medicinestomatognathic system0504 sociologymedicineAcupuncturebusiness.industry05 social sciencesMasticatory muscleSymptomatic reliefTemporomandibular jointMasticatory forcestomatognathic diseasesmedicine.anatomical_structureComplementary and alternative medicineCraniomandibular DisorderTemporomandibular acupuncturePhysical therapyEtiologyClinical casePresentation (obstetrics)business030217 neurology & neurosurgeryHeadaches and postural
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