Search results for "RICS"

showing 10 items of 14086 documents

Age-dependent decline of steady state dopamine storage capacity of human brain: an FDOPA PET study.

2010

Conventional indices of the utilization of FDOPA in living human brain have not consistently revealed important declines in dopamine function with normal aging. However, most methods of kinetic analysis have assumed irreversible trapping of decarboxylated FDOPA metabolites in brain, an assumption that is violated even in PET recordings of short duration. Therefore, we have developed methods for the calculation of steady-state storage of FDOPA together with its decarboxylated metabolites (V(d), mlg(-1)), based upon improved kinetic analysis of 120-min emission recordings. In a group of 28 normal male subjects, of age ranging from 23 to 73 years, the magnitude of V(d) in the striatum and in e…

AdultMalemedicine.medical_specialtyAgingMonoamine oxidaseDopamineModels NeurologicalStriatumchemistry.chemical_compoundYoung AdultDopamineInternal medicinemedicineHumansNeurotransmitterAgedCerebral CortexAromatic L-amino acid decarboxylaseChemistryGeneral NeuroscienceBrainHuman brainMiddle AgedCorpus StriatumKineticsmedicine.anatomical_structureEndocrinologyCerebral cortexPositron-Emission TomographyCatecholamineDopa DecarboxylaseNeurology (clinical)Geriatrics and GerontologyDevelopmental Biologymedicine.drugNeurobiology of aging
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Lower limb muscle weakness predicts use of a multiple- versus single-step strategy to recover from forward loss of balance in older adults.

2012

BACKGROUND: Older adults compared with young adults have reduced strength and balance recovery ability. The purpose of the present study was to investigate whether age, sex, and/or lower limb strength predicted the stepping strategy used to recover from a forward loss of balance. METHODS: Ninety-five, community-dwelling, older adults, aged 65-90 years, participated in the study. Loss of balance was induced by releasing participants from a static forward lean. Participants performed four trials at three initial lean magnitudes and were subsequently classified as using a single- or multiple-step strategy. Isometric strength of the ankle, knee, and hip joint flexors and extensors was assessed …

AdultMalemedicine.medical_specialtyAgingMovementPoison controlIsometric exerciseLogistic regressionRisk AssessmentPhysical medicine and rehabilitationSex FactorsPredictive Value of TestsmedicineOdds RatioReaction TimeHumansProspective StudiesMuscle SkeletalPostural BalanceBalance (ability)AgedAged 80 and overAnalysis of VarianceMuscle Weaknessbusiness.industryLower limb muscle weaknessAge FactorsMuscle weaknessStepwise regressionmedicine.anatomical_structureLogistic ModelsLower ExtremitySensation DisordersPhysical therapyAccidental FallsFemaleGeriatrics and Gerontologymedicine.symptomAnklebusinessThe journals of gerontology. Series A, Biological sciences and medical sciences
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Standing up from a chair as a dynamic equilibrium task: a comparison between young and elderly subjects.

2000

The purpose of this study was to analyze and compare the features of center of mass (CoM) control along anterior/posterior axis in young and elderly subjects during sit-to-stand (STS). From a sitting position, seven healthy young subjects and seven healthy elderly subjects were asked to stand up from a chair under different experimental conditions (visual conditions: normal and blindfolded; speed: normal and as fast as possible). Analysis of results was based upon the concept of a “dynamic equilibrium area” (DEA), which in turn identified the dynamic limits of balance. The results showed that both the maximal CoM velocity in the horizontal axis and the CoM velocity at the instant of seat-of…

AdultMalemedicine.medical_specialtyAgingOptics and PhotonicsTime FactorsBody heightMovementeducationPostureSittingBase of supportDisplacement (vector)Motion (physics)Physical medicine and rehabilitationTask Performance and AnalysisMedicineHumansPostural BalanceVision OcularBalance (ability)AgedHorizontal axisAged 80 and overLegbusiness.industryBody WeightHealthy elderlyhumanitiesBody HeightLinear ModelsFemaleStress MechanicalGeriatrics and GerontologyElectronicsbusinesshuman activitiesAlgorithmsThe journals of gerontology. Series A, Biological sciences and medical sciences
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Changes in muscle morphology, electromyographic activity, and force production characteristics during progressive strength training in young and olde…

1998

Effects of a 10-week progressive strength training program composed of a mixture of exercises for increasing muscle mass, maximal peak force, and explosive strength (rapid force production) were examined in 8 young (YM) (29+/-5 yrs) and 10 old (OM) (61+/-4 yrs) men. Electromyographic activity, maximal bilateral isometric peak force, and maximal rate of force development (RFD) of the knee extensors, muscle cross-sectional area (CSA) of the quadriceps femoris (QF), muscle fiber proportion, and fiber areas of types I, IIa, IIb, and IIab of the vastus lateralis were evaluated. Maximal and explosive strength values remained unaltered in both groups during a 3-week control period with no training…

AdultMalemedicine.medical_specialtyAgingVastus lateralis muscleStrength trainingMuscle Fibers SkeletalElectromyographyIsometric exerciseMuscle massMuscle hypertrophyMuscle morphologyInternal medicineMedicineHumansKneeMuscle SkeletalPhysical Education and Trainingmedicine.diagnostic_testbusiness.industryElectromyographySkeletal muscleAnatomyMiddle AgedEndocrinologymedicine.anatomical_structureGeriatrics and GerontologybusinessThe journals of gerontology. Series A, Biological sciences and medical sciences
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Idiopathic Trigeminal Neuropathies: A Presentation of 15 Cases

2008

Purpose The aim of this study is to present a clinical series of patients with trigeminal neuropathy and their treatment. Patients and Methods We present a retrospective study of 15 cases of idiopathic trigeminal neuropathies, with unilateral involvement of 1 or more divisions of the trigeminal nerve. The clinical, radiologic, and laboratory data of the patients, in addition to the treatment and clinical evolution, were reviewed. The patients were followed up for a mean of 34.4 months (range, 12-120 months). Results The study consisted of 11 women and 4 men. The numbness was predominantly located in the innervated mental area and extended in some cases to the first and second trigeminal div…

AdultMalemedicine.medical_specialtyAmitriptylineCohort StudiesHypesthesiaYoung AdultFacial PainHumansMedicineAmitriptylineYoung adultAgedRetrospective StudiesTrigeminal nerveMild painbusiness.industryRetrospective cohort studyRecovery of FunctionAnalgesics Non-NarcoticMiddle AgedTrigeminal NeuralgiaNeurogenic painSurgeryOtorhinolaryngologyAnesthesiaSensation DisordersFemaleSurgeryOral SurgeryPresentation (obstetrics)businessCohort studymedicine.drugJournal of Oral and Maxillofacial Surgery
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Immunization Campaigns and Strategies against Human Papillomavirus in Italy: The Results of a Survey to Regional and Local Health Units Representativ…

2019

Objective. The study aimed to assess the impact of HPV immunization campaigns organizational aspects, the characteristics of immunization program (vaccination targets and type of offer), and communicative strategies adopted by four Italian administrative regions on vaccination coverage observed. Methods. From November 2017 to March 2018, regional and Local Health Units (LHUs) representatives were invited to complete an online survey including 54 questions evaluating vaccination invite systems, access systems to vaccination centres, reminder and recall systems, and adverse events surveillance. An overall descriptive analysis was conducted. Since observed vaccine coverage (VC) obtained in fem…

AdultMalemedicine.medical_specialtyArticle SubjectImmunization registryMEDLINElcsh:MedicineGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicine030225 pediatricsHealth careHumansMedicinePapillomavirus Vaccines030212 general & internal medicineHuman papillomavirusSurveyPapillomaviridaeCopaymentGeneral Immunology and MicrobiologyDescriptive statisticsImmunization Campaigns and StrategieImmunization Programsbusiness.industryPapillomavirus InfectionsVaccinationlcsh:RAdult; Female; Humans; Immunization Programs; Italy; Male; Papillomaviridae; Papillomavirus Infections; Papillomavirus Vaccines; VaccinationGeneral MedicineVaccinationHuman PapillomaviruItalyImmunizationFamily medicineFemalebusinessResearch ArticleBioMed Research International
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Changes in Daily Steps and Body Mass Index and Waist to Height Ratio during Four Year Follow-Up in Adults: Cardiovascular Risk in Young Finns Study

2017

Aims: Over the study years, there was a significant increase in body mass index (BMI) and waist-to-height ratio (WtHR) in middle aged Finnish adults. Methods: Data were obtained from 1033 Finnish adults from the Cardiovascular Risk in Young Finns Study in 2007 and 2011. Cohort study participants wore an Omron Walking Style One (HJ-152R-E) pedometer for five days and were grouped into those who increased, maintained and decreased their steps between 2007 and 2011. Paired samples t-test was used to compare body mass index (BMI) and waist-to-height ratio (WtHR) change values between the change groups in study years. Results: Among study population BMI and WtHR increase between study years was …

AdultMalemedicine.medical_specialtyBiolääketieteet - BiomedicineHealth Toxicology and Mutagenesisphysical activitylcsh:Medicinebody mass indexWalking030204 cardiovascular system & hematologywaist-to-height ratioArticle03 medical and health sciences0302 clinical medicinePaired samplesadultsfollow-upHumansMedicine030212 general & internal medicinepainoindeksita315FinlandaskelmittaritaikuisetWaist-to-height ratioWaist-Height Ratiopedometerphysical activity; pedometer; adults; follow-up; body mass index; waist-to-height ratiobusiness.industrylcsh:RSisätaudit - Internal medicinePublic Health Environmental and Occupational HealthFollow up studiesNaisten- ja lastentaudit - Gynaecology and paediatricsMiddle Agedta3121Middle agePedometerPhysical therapyPopulation studyFemalebusinessBody mass indexfyysinen aktiivisuusFollow-Up StudiesCohort studyInternational Journal of Environmental Research and Public Health
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Recurrent brief depression in general practice. Clinical features, comorbidity with other disorders, and need for treatment.

1994

This study tested the clinical validity of the new diagnostic entity "recurrent brief depression" (RBD) in 300 general practice patients who participated in the WHO study on "Psychological Problems in Primary Care." Patients with current RBD reported of episodes major depression more often than did a comparison group of nondepressed general practice patients: however, the majority of RBD patients had not received a diagnostic of any well-established affective disorder during the last 12 months. RBD patients (without MDE) did not suffer more frequently from dysthymia, from nonaffective psychiatric disorders, or from somatic disorders. However, RBD was associated with a higher percentage of p…

AdultMalemedicine.medical_specialtyBipolar DisorderAdolescentPsychometricsPoison controlSuicide AttemptedComorbidityPersonality AssessmentRecurrent brief depressionRecurrenceGermanyInjury preventionActivities of Daily LivingmedicineHumansPharmacology (medical)Bipolar disorderPsychiatrySomatoform DisordersBiological PsychiatryDepression (differential diagnoses)AgedDepressive DisorderPrimary Health Carebusiness.industryIncidenceGeneral MedicineMiddle Agedmedicine.diseaseComorbidityPsychiatry and Mental healthCross-Sectional StudiesFemalePersonality Assessment InventorybusinessPsychosocialClinical psychologyEuropean archives of psychiatry and clinical neuroscience
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Personality traits in subjects at risk for unipolar major depression: A family study perspective

1992

Particular patterns of personality (e.g., introversion, neuroticism, obsessionality) have been found to be associated with unipolar depression by a large number of investigators; recent prospective studies have stressed neuroticism as a premorbid risk factor for depression. This study examines whether similar patterns of personality are found in relatives of affective disorder patients and of controls. First-degree relatives of normal controls and of subjects with primary unipolar depression were studied using the Munich Personality Test. Relatives in remission from an episode of unipolar depression had clearly higher levels of neuroticism and rigidity and lower levels of extraversion than …

AdultMalemedicine.medical_specialtyBipolar DisorderPersonality InventoryPsychometricsmedia_common.quotation_subjectSex FactorsChild of Impaired ParentsRecurrenceRisk Factorsmental disordersmedicineHumansPersonalityBipolar disorderPersonality testBig Five personality traitsPsychiatrymedia_commonDepressive DisorderExtraversion and introversionMiddle Agedmedicine.diseaseNeuroticismAlcoholismPsychiatry and Mental healthClinical PsychologyPhobic DisordersPanic DisorderFemalePersonality Assessment InventoryPsychologyPersonalityJournal of Affective Disorders
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Clinical usefulness of the screen for cognitive impairment in psychiatry (SCIP-S) scale in patients with type I bipolar disorder

2009

Abstract Background The relevance of persistent cognitive deficits to the pathogenesis and prognosis of bipolar disorders (BD) is understudied, and its translation into clinical practice has been limited by the absence of brief methods assessing cognitive status in Psychiatry. This investigation assessed the psychometric properties of the Spanish version of the Screen for Cognitive Impairment in Psychiatry (SCIP-S) for the detection of cognitive impairment in BD. Methods After short training, psychiatrists at 40 outpatient clinics administered the SCIP three times over two weeks to a total of 76 consecutive type I BD admissions. Experienced psychologists also administered a comprehensive ba…

AdultMalemedicine.medical_specialtyBipolar DisorderPsychometricsAdolescentPsychometricslcsh:Computer applications to medicine. Medical informaticsAmbulatory Care FacilitiesSensitivity and SpecificityYoung AdultCognitionQuality of lifemedicineManic-depressive illnessOutpatient clinicHumansBipolar disorderPsychiatryTrastorn bipolarResearchNeuropsychologyPublic Health Environmental and Occupational HealthConstruct validityReproducibility of ResultsCognitionGeneral MedicineMiddle Agedmedicine.diseaseDiagnostic and Statistical Manual of Mental DisordersLogistic ModelsROC CurveSpainCase-Control StudiesCogniciólcsh:R858-859.7FemalePsicometriaPsychologyCognition DisordersNeurocognitiveClinical psychologyHealth and Quality of Life Outcomes
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