Search results for "RICS"

showing 10 items of 14086 documents

A novel Angiogenin gene mutation in a sporadic patient with amyotrophic lateral sclerosis from southern Italy

2007

Mutations in the Angiogenin gene (ANG) linked to 14q11.2 have been recently discovered to be associated with Amyotrophic Lateral Sclerosis (ALS) in Irish and Scottish populations. In our study we investigated the role of ANG gene in ALS patients from southern Italy. We found a novel mutation in the signal peptide of the ANG gene in a sporadic patient with ALS (SALS). The molecular analysis of the ANG gene also demonstrated an allelic association with the rs11701 single nucleotide polymorphism (SNP) in familial ALS (FALS) but not in SALS patients. Our finding supports the evidence that the ANG gene is involved in ALS.

AdultGenetic MarkersMaleSignal peptideAngiogenin geneAngiogeninGenetic LinkageDNA Mutational AnalysisSingle-nucleotide polymorphismGene mutationBiologyPolymorphism Single NucleotidemedicineHumansSNPGenetic Predisposition to DiseaseGenetic TestingAlleleAmyotrophic lateral sclerosisGeneGenetics (clinical)AgedChromosomes Human Pair 14Motor NeuronsGeneticsAmyotrophic Lateral SclerosisChromosome MappingRibonuclease PancreaticMiddle Agedmedicine.diseaseAssociation studyAmino Acid SubstitutionItalyNeurologyCytoprotectionMutationNerve DegenerationPediatrics Perinatology and Child Healthcardiovascular systemCancer researchFemaleNeurology (clinical)ALShormones hormone substitutes and hormone antagonistsNeuromuscular Disorders
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Childcare, height and BMI among female Polish university students, 2005

2007

The aim of this study is to consider whether socio-economic factors are related to the type of childcare and whether the type of childcare, in turn, affects adult stature and BMI. The sample includes 783 female students aged 20-24 (birth cohort of 1981-1985) from the south of Poland. Those whose parents have university education, live in a city and have no siblings attend day-care facilities more frequently than others of the same age, while those who grew up at home under their mothers' care, most frequently live in villages, come from large families and their parents have vocational education. Variables which are associated with being taller include material conditions and the type of chi…

AdultGerontologyAdolescentUniversitiesCross-sectional studyEconomics Econometrics and Finance (miscellaneous)OverweightBody Mass IndexmedicineHumansUniversity educationObesityChild CareChildStudentsFemale studentsSocioeconomic statusbusiness.industryOverweightNutrition Surveysmedicine.diseaseObesityBody HeightCross-Sectional StudiesSocioeconomic FactorsChild PreschoolVocational educationEducational StatusFemaleGrowth and DevelopmentPolandmedicine.symptombusinessBody mass indexEconomics & Human Biology
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Fast food consumption and gestational diabetes incidence in the SUN project.

2014

Background: Gestational diabetes prevalence is increasing, mostly because obesity among women of reproductive age is continuously escalating. We aimed to investigate the incidence of gestational diabetes according to the consumption of fast food in a cohort of university graduates. Methods: The prospective dynamic ‘‘Seguimiento Universidad de Navarra’’ (SUN) cohort included data of 3,048 women initially free of diabetes or previous gestational diabetes who reported at least one pregnancy between December 1999 and March 2011. Fast food consumption was assessed through a validated 136-item semi-quantitative food frequency questionnaire. Fast food was defined as the consumption of hamburgers, …

AdultGerontologySettore MED/09 - Medicina InternaMaternal Healthlcsh:MedicineCohort StudiesFast foodPregnancyDiabetes mellitusConfidence IntervalsOdds RatioMedicine and Health SciencesDiabetes MellitusmedicineHumansSUN ProjectRisk factorlcsh:ScienceGestational diabetesNutritionPregnancyMultidisciplinarybusiness.industryIncidencelcsh:RBiology and Life SciencesObstetrics and Gynecologymedicine.diseaseObesityDietType 2 DiabetesPregnancy ComplicationsGestational diabetesDiabetes GestationalDiet and Type 2 DiabetesSpainMetabolic DisordersCohortFast FoodsWomen's HealthFemalelcsh:Qbusinessfastfood gestational diabetes body mass index cohort prospectiveBody mass indexResearch ArticleDemographyCohort studyPLoS ONE
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Livebirth after uterus transplantation.

2015

Uterus transplantation is the first available treatment for absolute uterine infertility, which is caused by absence of the uterus or the presence of a non-functional uterus. Eleven human uterus transplantation attempts have been done worldwide but no livebirth has yet been reported.In 2013, a 35-year-old woman with congenital absence of the uterus (Rokitansky syndrome) underwent transplantation of the uterus in Sahlgrenska University Hospital, Gothenburg, Sweden. The uterus was donated from a living, 61-year-old, two-parous woman. In-vitro fertilisation treatment of the recipient and her partner had been done before transplantation, from which 11 embryos were cryopreserved.The recipient an…

AdultGraft RejectionMalemedicine.medical_specialty46 XX Disorders of Sex Developmentmedicine.medical_treatmentUterusFertilization in VitroTacrolimusCongenital AbnormalitiesGynecologic Surgical ProceduresPre-EclampsiaAdrenal Cortex HormonesPregnancyUterus transplantationAzathioprinemedicineLiving DonorsHumansCaesarean sectionMullerian DuctsSwedenPregnancybusiness.industryObstetricsCesarean SectionUterusInfant NewbornGestational ageImmunosuppressionGeneral Medicinemedicine.diseaseEmbryo TransferSurgeryTransplantationmedicine.anatomical_structureApgar ScoreApgar scoreFemalebusinessLive BirthImmunosuppressive AgentsInfant PrematureLancet (London, England)
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Uterus transplantation trial: 1-year outcome

2014

Objective To report the 12-month outcome of seven patients with viable uteri after uterus transplantation (UTx). Design Prospective observational study. Setting University hospital. Patient(s) Seven patients with absolute uterine infertility and viable uteri for 12 months after live-donor UTx. Intervention(s) Predetermined immunosuppression was with tacrolimus and mychophenolate mofetil (MMF) during 6 months, whereupon MMF should be withdrawn. Frequent ultrasound examinations were performed to assess uterine appearance and uterine artery blood flow. Cervical biopsies (for histological detection of rejection) were obtained at preset time points, with temporary adjustments of immunosuppressio…

AdultGraft Rejectionmedicine.medical_specialtymedicine.medical_treatmentUterusUrologyAzathioprineMenstruationsmedicine.arteryUterus transplantationHumansMedicineLongitudinal StudiesProspective StudiesUterine arterybusiness.industryUterusFertility PreservationObstetrics and GynecologyImmunosuppressionOrgan TransplantationTacrolimusSurgeryTransplantationTreatment Outcomemedicine.anatomical_structureReproductive MedicineFemalebusinessInfertility FemaleImmunosuppressive Agentsmedicine.drugFertility and Sterility
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Congenital Müllerian anomalies: diagnostic accuracy of three-dimensional ultrasound

1996

Objective To determine whether it is possible to identify and diagnose accurately Mullerian anomalies with three-dimensional (3-D) ultrasound (US). Design Controlled blinded clinical study. Setting Normal human volunteers undergoing infertility evaluation in a university hospital. Patients Forty-two patients who underwent laparoscopy and hysterosalpingography as part of their work up for infertility and were found to have either a normal uterus (30 patients) or a Mullerian abnormality (12 patients) consented to be evaluated with 3-D US by sonographers who were unaware of their infertility history or of their laparoscopy and hysterosalpingography diagnoses. Interventions Transvaginal 3-D US …

AdultGynecologyInfertilitymedicine.medical_specialtymedicine.diagnostic_testArcuate uterusbusiness.industryUltrasoundObstetrics and Gynecologymedicine.diseaseWork-upReproductive MedicineEvaluation Studies as TopicImage Processing Computer-AssistedmedicineEtiologyAnimalsHumansHysterosalpingographyRadiologyAbnormalityLaparoscopybusinessMullerian DuctsUltrasonographyFertility and Sterility
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Transient CD15-positive endothelial phenotype in the human placenta correlates with physiological and pathological fetoplacental immaturity

2013

Abstract Objective Placental growth and villous maturation are critical parameters of placental function at the end of pregnancy. A failure in these processes leads to the development of placental dysfunction, as well as fetal and neonatal mortality and morbidity. The aim of the study was to determine the relevant diagnostic markers associated with pathological placental development. Study design Forty tissue samples from normal placentas of different gestational age and 68 pathological term placentas with defective villous maturation (GDM, idiopathic IUFD, preeclamsia, HELLP syndrome) comprised the comparative immunohistochemical study (CD15, CD45 and CD34). Positive immunohistochemical re…

AdultHELLP SyndromePathologymedicine.medical_specialtyStromal cellEndotheliumHELLP syndromePlacentaCD34Lewis X AntigenAntigens CD34Gestational AgePre-EclampsiaPregnancymedicineHumansPathologicalPregnancyFetusFetal Growth Retardationbusiness.industryEndothelial CellsObstetrics and GynecologyFucosyltransferasesmedicine.diseaseImmunohistochemistryPlacentationDiabetes Gestationalmedicine.anatomical_structureReproductive MedicineCase-Control Studiesembryonic structuresLeukocyte Common AntigensImmunohistochemistryFemalebusinessEuropean Journal of Obstetrics & Gynecology and Reproductive Biology
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Awareness of HPV infection and attitudes toward HPV vaccination among Latvian adolescents

2016

Objective\ud To evaluate awareness of HPV and its vaccine among Latvian adolescents.\ud \ud Methods\ud A cross‐sectional survey was conducted in a 2‐week period in September 2015 among 270 adolescents attending a secondary school in Riga, Latvia. All students present during sexual‐health classes (grades 10–12 [aged 16–21 years]) were included. A self‐administered paper‐based survey assessed sociodemographic factors, sexual behaviours, smear history and knowledge of sexually transmitted infections, HPV and HPV vaccine knowledge, and sources of information.\ud \ud Results\ud Overall, 121 surveys were completed (62 by male students and 59 by female students). Latvian adolescents lacked awarene…

AdultHealth Knowledge Attitudes PracticeAdolescentPopulationUterine Cervical Neoplasms03 medical and health sciencesSexually active0302 clinical medicineRA0421Surveys and QuestionnairesPrevalenceHumansMedicinePapillomavirus Vaccines030212 general & internal medicineeducationFemale studentseducation.field_of_studyHigh prevalencebusiness.industryPapillomavirus InfectionsHPV infectionObstetrics and GynecologyLatvianHpv vaccinationGeneral MedicinePatient Acceptance of Health Caremedicine.diseaseLatviaR1female genital diseases and pregnancy complicationslanguage.human_languageVaccinationAdolescent Behavior030220 oncology & carcinogenesisImmunologylanguageWomen's HealthFemalebusinessDemographyInternational Journal of Gynecology & Obstetrics
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Reproductive health problems in rural South African young women: risk behaviour and risk factors

2018

Background South African young women continue to be vulnerable, with high prevalence of teenage pregnancy, HIV, sexually transmitted infections (STIs) and female genital schistosomiasis (FGS). This study seeks to examine the underlying factors that may be associated with these four adverse reproductive health outcomes. Methods In a cross-sectional study of 1413 sexually active of young women, we explored these four adverse reproductive health outcomes by considering socio-demographic factors, socio-economic factors, sexual risk behaviour, substance abuse and knowledge about reproductive health by using a questionnaire. Consenting participants were asked about previous pregnancies and were t…

AdultHealth Knowledge Attitudes Practicemedicine.medical_specialtyAdolescentSexual Behavior030231 tropical medicinePopulationSexually Transmitted DiseasesReproductive medicineHIV InfectionsHealth literacylcsh:Gynecology and obstetricsSouth Africa03 medical and health sciencesRisk-Taking0302 clinical medicine5. Gender equalityPregnancyRisk FactorsEnvironmental healthHealth carePrevalencemedicineHumans030212 general & internal medicineChildeducationlcsh:RG1-991Reproductive healthTeenage pregnancyeducation.field_of_studybusiness.industryResearchPublic healthInfant NewbornObstetrics and Gynecology3. Good healthCross-Sectional StudiesReproductive HealthReproductive MedicinePregnancy in AdolescenceFemaleRural areabusiness
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Risk factors for unwanted pregnancy and subsequent abortion among women aged 16 to 25 years in Latvia

2015

Objective To investigate the risk factors associated with unwanted pregnancy in 16- to 25-year-old women in Latvia. Methods Case-control study of 16- to 25-year-old, sexually active women who did not want to get pregnant: the cases were 144 women who underwent their fi rst abortion whereas 278 nulliparous women served as controls. Data concerning them were obtained by using a semi-structured anonymous questionnaire that included questions about education, sexual life habits, contraceptive practice and a multiple-choice test to assess knowledge about contraception. Results Women who underwent an abortion had had more lifetime sexual partners, had more often not used any contraception, and we…

AdultHealth Knowledge Attitudes Practicemedicine.medical_specialtyAdolescentSexual Behaviormedia_common.quotation_subjectPopulationDeveloping countryFertilityAbortionHealth Services AccessibilityYoung AdultPregnancyRisk FactorsHumansMedicinePharmacology (medical)Young adulteducationContraception BehaviorReproductive healthmedia_commonGynecologyeducation.field_of_studybusiness.industryCase-control studyObstetrics and GynecologyAbortion InducedLatviaPregnancy UnwantedContraceptionSexual PartnersReproductive MedicineFamily planningFemalebusinessDemographyThe European Journal of Contraception & Reproductive Health Care
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