Search results for "RIG"
showing 10 items of 9548 documents
PROBLEMATYKA ZNAMION PRZESTĘPSTWA Z ART. 191A USTAWY KARNEJ ORAZ JEGO UMIEJSCOWIENIE W SYSTEMATYCE KODEKSOWEJ
2018
Artykuł poddaje analizie zasadność penalizacji z art.191a ustawy karnej, a także jego umiejscowienie w systematyce kodeksowej, konfrontując stanowiska doktryny prawa karnego przy uwzględnieniu trudności interpretacyjnych podczas jego praktycznego stosowania. Ponadto zostały omówione znamiona przedmiotowego przepisu, które w konsekwencji doprowadziły do konkluzji, iż istnieje potrzeba znowelizowania art. 191a, dodając do niego typ kwalifikowany przestępstwa, skutkującego targnięciem się poszkodowanego na swoje życie.
sub artt. 46 e 47 d.lgs. n. 150/2009
2011
Maternal identity and double belongings: the experience of motherhood in a foreign country
2009
Le rôle du marché des dirigeants dans le système de gouvernance des entreprises : une revue de la littérature
2005
National audience; L'objectif de cet article est, en s'appuyant sur la littérature existante, d'appréhender et de comprendre le rôle d'un mécanisme particulier:le marché des dirigeants, à l'intérieur du système de gouvernance des entreprises. La grille de lecture utilisée est synthétique, permettant d'étudier les voies d'intervention potentielles du marché managérial aussi bien sous la dimension disciplinaire que cognitive. L'apport principal de cet article est d'aboutir à une vision globale et complète du rôle de ce mécanisme, venant remettre en cause la perception généralement négative du marché des dirigeants, considéré inefficient, de type clanique, notamment en France. Cette revue cons…
Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea
2019
Background: Thyroid cancer has become the most common cancer in Korea. Generally, thyroid cancer patients have a good prognosis; however, 15–20% of patients experience recurrence or distant metastasis or are refractory to standard treatment. We assessed the safety of sorafenib and lenvatinib in patients with advanced or metastatic radioactive iodine-refractory differentiated thyroid cancers (DTC) consecutively treated at a tertiary center in South Korea.Methods: We retrospectively reviewed the charts of all consecutive patients with DTC treated during ≥6 months with lenvatinib (February 2016–April 2018) and sorafenib (January 2014–April 2018) at Gangnam Severance Hospital. Patients were tre…
Safety and immunogenicity of the PRAME cancer immunotherapeutic in metastatic melanoma: results of a phase I dose escalation study
2016
Purpose The PRAME tumour antigen is expressed in several tumour types but in few normal adult tissues. A dose-escalation phase I/II study (NCT01149343) assessed the safety, immunogenicity and clinical activity of the PRAME immunotherapeutic (recombinant PRAME protein (recPRAME) with the AS15 immunostimulant) in patients with advanced melanoma. Here, we report the phase I dose-escalation study segment. Patients and methods Patients with stage IV PRAME-positive melanoma were enrolled to 3 consecutive cohorts to receive up to 24 intramuscular injections of the PRAME immunotherapeutic. The RecPRAME dose was 20, 100 or 500 µg in cohorts 1, 2 and 3, respectively, with a fixed dose of AS15. Advers…
Polyphenols and Pharmacological Screening of a Monarda fistulosa L. dry Extract Based on a Hydrodistilled Residue By-Product
2021
This study aimed to determine the composition and content of polyphenols in the dry extract obtained from the hydrodistilled residue by-product of the wild bergamot (Monarda fistulosa L., Lamiaceae Martinov family) herb (MFDE) and to evaluate its safety and pharmacological properties. The total phenolic content (TPC) in the MFDE was 120.64 mg GAE/g. The high-performance liquid chromatography (HPLC) analysis showed the presence of a plethora of phenolic compounds, including hydroxycinnamic acids and flavone derivatives in the MFDE, with rosmarinic acid and luteolin-7-O-glucoside being the main components. With an IC50 value of 0.285 mg/mL, it was found to be a strong DPPH radical scavenger. …
Comparable efficacy and safety of dimethyl fumarate and teriflunomide treatment in Relapsing-Remitting Multiple Sclerosis: an Italian real-word multi…
2018
BACKGROUND: The aim of the study was to evaluate the achievement of 'no evidence of disease activity' (NEDA) over a 12-month period in a large multicenter population with relapsing remitting multiple sclerosis (RRMS) treated with delayed-release dimethyl fumarate (DMF) and teriflunomide (TRF) using a propensity-score adjustment. METHODS: A time-to-event method was used to determine the percentages of patients with RRMS (pwRRMS) in both groups achieving NEDA 3 (no relapses, no 12-week confirmed disability progression, and no new T2/gadolinium-enhancing brain lesions). We described the safety profile of the investigated drugs. RESULTS: Of the 587 pwRRMS treated with DMF and the 316 pwRRMS tre…
Safety and Tolerance Evaluation of Milk Fat Globule Membrane-Enriched Infant Formulas: A Randomized Controlled Multicenter Non-Inferiority Trial in H…
2014
ObjectiveThis multicenter non-inferiority study evaluated the safety of infant formulas enriched with bovine milk fat globule membrane (MFGM) fractions.MethodsHealthy, full-term infants ( n = 119) age ≤14 days were randomized to standard infant formula (control), standard formula enriched with a lipid-rich MFGM fraction (MFGM-L), or standard formula enriched with a protein-rich MFGM fraction (MFGM-P). Primary outcome was mean weight gain per day from enrollment to age 4 months (non-inferiority margin: –3.0 g/day). Secondary (length, head circumference, tolerability, morbidity, adverse events) and exploratory (phospholipids, metabolic markers, immune markers) outcomes were also evaluated.Res…
“Impressioni sulla Sagra del Mandorlo in Fiore”: storia di un premio di pittura dimenticato.
2010
1.“Impressioni sulla Sagra del Mandorlo in Fiore”: storia di un premio di pittura dimenticato, pp. 11-22, in Dal folklore all'arte. “Impressioni sulla Sagra del Mandorlo in Fiore” nella pittura del Novecento, catalogo della mostra (Agrigento, Scala Reale del Palazzo della Provincia, 18 febbraio- 4 marzo 2010) a cura di G. COSTANTINO, G. CIPOLLA, R. FERLISI, Edizioni Lussografica, Caltanissetta 2010 (ISBN: 978-88-8243-232-4)