Search results for "RILL"

showing 10 items of 1272 documents

Cell type heterogeneity of intermediate filament expression in epithelia of the human pituitary gland.

1989

In the present study we have localized immunohistochemically the intermediate filament proteins of the human pituitary gland (adenohypophysis, pars intermedia and pars tuberalis) by an indirect immunoperoxidase technique or by double immunofluorescence methods and analysed the individual cytokeratin polypeptides using two-dimensional gel electrophoresis. We found that the expression of cytokeratins in different epithelial cells of the human anterior pituitary gland was heterogeneous. Whereas the endocrine cells only expressed cytokeratins 8 and 18, the folliculo-stellate cells exhibited a reactivity for cytokeratins 7, 8, 18 and 19 as well as for GFAP and vimentin. The squamous epithelial c…

Malemedicine.medical_specialtyPituitary glandHistologyVimentinmacromolecular substancesEpitheliumDesminCytokeratinIntermediate Filament ProteinsInternal medicineGlial Fibrillary Acidic ProteinmedicineIntermediate Filament ProteinHumansVimentinIntermediate filamentMolecular BiologybiologyPars intermediaEpithelial CellsCell BiologyGeneral MedicineMolecular biologyImmunohistochemistryMedical Laboratory Technologymedicine.anatomical_structureEndocrinologyPituitary Glandbiology.proteinKeratinsFemalePars tuberalisAnatomyGeneral Agricultural and Biological SciencesEndocrine glandHistochemistry
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Incidence and prognostic significance of silent atrial fibrillation in acute myocardial infarction

2014

article Background: Silent atrial fibrillation (AF) has been suggested to be frequent after acute myocardial infarction (MI). Continuous ECG monitoring (CEM) has been shown to improve AF screening in patients at risk of stroke. Objectives: We aimed to assess the incidence and prognosis of silent AF in patients with acute MI. Methods:All the consecutive patients with acute MI were prospectively analyzed by CEM ≥ 48 h after admission. Silent AF was defined as asymptomatic episodes lasting at least 30 s. The population was divided into three groups: no-AF, silent AF and symptomatic AF. Results:Among the 849 patients, 135(16%) developedsilentAF and45(5%)symptomatic AF.Comparedwith the no-AF gro…

Malemedicine.medical_specialtyPopulationMyocardial InfarctionAsymptomatic[SHS]Humanities and Social SciencesInternal medicineAtrial FibrillationmedicineHumansProspective StudiesMyocardial infarctioneducationProspective cohort studyStrokeComputingMilieux_MISCELLANEOUSAgedAged 80 and overeducation.field_of_studyEjection fractionbusiness.industryIncidenceAge FactorsStroke VolumeAtrial fibrillationMiddle AgedPrognosismedicine.diseaseHeart failureCardiologyFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessInternational Journal of Cardiology
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Efficacy of a web-based intervention for improving psychosocial well-being in patients with implantable cardioverter-defibrillators: the randomized c…

2019

Abstract Aims Anxiety, depression, and reduced quality of life (QoL) are common in patients with implantable cardioverter-defibrillators (ICDs). Treatment options are limited and insufficiently defined. We evaluated the efficacy of a web-based intervention (WBI) vs. usual care (UC) for improving psychosocial well-being in ICD patients with elevated psychosocial distress. Methods and results This multicentre, randomized controlled trial (RCT) enrolled 118 ICD patients with increased anxiety or depression [≥6 points on either subscale of the Hospital Anxiety and Depression Scale (HADS)] or reduced QoL [≤16 points on the Satisfaction with Life Scale (SWLS)] from seven German sites (mean age 58…

Malemedicine.medical_specialtyPsychological interventionMixed anxiety-depressive disorderAnxiety030204 cardiovascular system & hematologyHospital Anxiety and Depression Scalelaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialQuality of lifelawmedicineHumansAgedCognitive Behavioral TherapyDepressionbusiness.industry030229 sport sciencesMiddle Agedmedicine.diseaseDefibrillators ImplantableDistressQuality of LifePhysical therapyAnxietyFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessPsychosocialInternet-Based InterventionEuropean Heart Journal
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Use of direct oral anticoagulants in very elderly patients: a case report of apixaban in an ultracentenary patient.

2019

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Malemedicine.medical_specialtyPyridonesFrail ElderlyTreatment outcomeMEDLINEAdministration Oralanticoagulants elderlyAtrial FibrillationmedicineHumansFrail elderlyIntensive care medicineGeriatric AssessmentAged 80 and overbusiness.industryGeriatric assessmentGeneral MedicineSettore MED/11 - Malattie Dell'Apparato CardiovascolareChronic diseaseTreatment OutcomeChronic DiseasePyrazolesApixabanCardiology and Cardiovascular Medicinebusinessmedicine.drugFactor Xa InhibitorsJournal of cardiovascular medicine (Hagerstown, Md.)
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Prognosis, disease progression, and treatment of atrial fibrillation patients during 1 year: follow-up of the Euro Heart Survey on Atrial Fibrillation

2008

Aims: To gain insight in the prognosis and treatment of atrial fibrillation (AF) patients during 1-year follow-up in the Euro Heart Survey (EHS) on AF. Methods and results: The EHS enrolled 5333 AF patients in 2003-2004. One-year follow-up data were available for 80%. Of first detected AF patients, 46% did not have a recurrence during 1 year, paroxysmal AF largely remained paroxysmal AF (80%), and 30% of persistent AF progressed to permanent AF. Many treatment changes occurred since baseline. Oral anticoagulation was started in 19% and discontinued in 16% of all patients. Of patients initially on rhythm control 27% did not receive rhythm control during follow-up, whereas 15% of patients ini…

Malemedicine.medical_specialtyRate controlHeart DiseasesHeart diseasePrognosiHemorrhageRisk AssessmentAnticoagulationElectrocardiographyInternal medicineAtrial FibrillationHumansMedicineSinus rhythmProspective StudiesMortalityProspective cohort studyStrokeSurvival rateAgedProgressionmedicine.diagnostic_testbusiness.industryAnticoagulantAnticoagulantsAtrial fibrillationPrognosismedicine.diseaseManagementStrokeSurvival RateProspective StudieHeart DiseaseTreatment OutcomeHeart failureDisease ProgressionCardiologyRhythm controlFemaleCardiology and Cardiovascular MedicinebusinessElectrocardiographyHumanEuropean Heart Journal
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Resting heart rate and cardiovascular outcomes in diabetic and non-diabetic individuals at high cardiovascular risk analysis from the ONTARGET/TRANSC…

2018

Abstract Aims Resting heart rate (RHR) has been shown to be associated with cardiovascular outcomes in various conditions. It is unknown whether different levels of RHR and different associations with cardiovascular outcomes occur in patients with or without diabetes, because the impact of autonomic neuropathy on vascular vulnerability might be stronger in diabetes. Methods and results We examined 30 937 patients aged 55 years or older with a history of or at high risk for cardiovascular disease and after myocardial infarction, stroke, or with proven peripheral vascular disease from the ONTARGET and TRANSCEND trials investigating ramipril, telmisartan, and their combination followed for a m…

Malemedicine.medical_specialtyRestHeart failure030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineHeart RateRisk FactorsInternal medicineDiabetes mellitusmedicineDiabetes MellitusHumansMyocardial infarctionProspective StudiesONTARGETStrokeProportional hazards modelbusiness.industryHazard ratioDiabetesAtrial fibrillation030229 sport sciencesMiddle Agedmedicine.diseaseCardiovascular riskMyocardial infarctionBlood pressureCardiovascular DiseasesHeart Disease Risk FactorsHeart failureCardiologyBlood pressureFemaleCardiology and Cardiovascular MedicinebusinessTRANSCENDEuropean heart journal
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Active compression-decompression resuscitation: a prospective, randomized study in a two-tiered EMS system with physicians in the field.

1996

Improved cardiopulmonary circulation with active compression-decompression cardiopulmonary resuscitation (ACD-CPR) has been demonstrated in studies using different animal models and a small number of humans in cardiac arrest (CA). However, prehospital studies have shown both positive and no extra benefit of ACD-CPR on return of spontaneous circulation (ROSC), hospital admission and discharge rates. The aim of our prospective study was to compare standard manual CPR (S-CPR) with ACD-CPR as the initial technique of resuscitating patients with out-of-hospital CA, with respect to survival rates and neurological outcome. Patients with out-of-hospital CA treated by emergency medical services (EMS…

Malemedicine.medical_specialtyResuscitationEmergency Medical ServicesDefibrillationmedicine.medical_treatmenteducationEmergency NursingReturn of spontaneous circulationlaw.inventionRandomized controlled triallawhealth services administrationmedicineEmergency medical servicesHumanscardiovascular diseasesCardiopulmonary resuscitationProspective StudiesProspective cohort studyhealth care economics and organizationsbusiness.industryIntensive care unitSurvival AnalysisCardiopulmonary ResuscitationSurgeryTreatment OutcomeAnesthesiaEmergency MedicineFemaleCardiology and Cardiovascular MedicinebusinesstherapeuticsResuscitation
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Should subcutaneous implantable cardioverter-defibrillators be implanted in patients who are candidates for continuous flow left ventricular assist d…

2017

Malemedicine.medical_specialtyResuscitationPacing resynchronization/biventricular/all modalitiesmedicine.medical_treatmentResuscitation030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineArrhythmia therapyCirculatory support devicesMinimally invasive surgeryInternal medicineInternal MedicinemedicineHumansMinimally Invasive Surgical ProceduresIn patient030212 general & internal medicineAgedHeart FailureContinuous flowbusiness.industryMiddle Agedmedicine.diseaseDefibrillators ImplantableVentricular assist deviceHeart failureCardiologyFemaleHeart-Assist Devicesbusiness
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Helicobacter pylori and atrial fibrillation: absence of correlations

2009

Malemedicine.medical_specialtyRisk AssessmentGastroenterologyHelicobacter InfectionsRisk FactorsInternal medicineAtrial FibrillationmedicineHumansProspective StudiesProspective cohort studyHelicobacter pyloribiologybusiness.industryCase-control studyAtrial fibrillationGeneral MedicineMiddle AgedHelicobacter pylorimedicine.diseaseHelicobacter Infectionsbiology.organism_classificationInflammatory mediatorHelicobacter pylori atrial fibrillationCase-Control StudiesFemaleInflammation MediatorsCardiology and Cardiovascular MedicineRisk assessmentbusinessBiomarkersJournal of Cardiovascular Medicine
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Factors affecting adherence to guidelines for antithrombotic therapy in elderly patients with atrial fibrillation admitted to internal medicine wards

2010

Abstract Introduction Current guidelines for ischemic stroke prevention in atrial fibrillation or flutter (AFF) recommend Vitamin K antagonists (VKAs) for patients at high-intermediate risk and aspirin for those at intermediate-low risk. The cost-effectiveness of these treatments was demonstrated also in elderly patients. However, there are several reports that emphasize the underuse of pharmacological prophylaxis of cardio-embolism in patients with AFF in different health care settings. Aims To evaluate the adherence to current guidelines on cardio-embolic prophylaxis in elderly (> 65 years old) patients admitted with an established diagnosis of AFF to the Italian internal medicine wards p…

Malemedicine.medical_specialtySettore MED/09 - Medicina InternaVitamin Kantithrombotic therapyNOAntithrombotic prophylaxis Atrial fibrillation Platelet agents Vitamin K antagonistsFibrinolytic AgentsRisk FactorsInternal medicineAntithromboticInternal MedicinemedicineHumansatrial fibrillationRegistriesMedical prescriptionStrokeAgedRetrospective StudiesAged 80 and overAntithrombotic prophylaxis; Atrial fibrillation; Platelet agents; Vitamin K antagonists;guidelines; antithrombotic therapy; atrial fibrillation.AspirinAspirinbusiness.industryantithrombotic prophylaxis; atrial fibrillation; platelet agents; vitamin k antagonistsAtrial fibrillationRetrospective cohort studyplatelet agentsmedicine.diseaseStrokevitamin k antagonistsIntracranial EmbolismItalyPlatelet aggregation inhibitorFemaleGuideline Adherenceantithrombotic prophylaxisbusinessguidelinePlatelet Aggregation InhibitorsFibrinolytic agentatrial fibrillation.medicine.drug
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