Search results for "RIP"
showing 10 items of 9780 documents
Transcultural Adaptation and Theoretical Models of Validation of the Spanish Version of the Self-Care of Heart Failure Index Version 6.2 (SCHFI v.6.2)
2021
Background: Heart failure (HF) is a major and growing public health problem worldwide. Across the world, heart failure is associated with high mortality, high hospitalization rates, and poor quality of life. Self-care is defined as a naturalistic decision-making process involving the choice of behaviors that maintain physiologic stability, the response to symptoms when they occur, and the ability to follow the treatment regimen and control symptoms. One instrument used to measure self-care is the Self Care of Heart Failure Index. Aim: The purpose of this study was to test the psychometric properties of the Spanish version of the Self Care of Heart Failure Index v.6.2 (SCHFI v.6.2). Methodol…
"Kansamme kykyyn itse arvostella ei voi luottaa!" : taidelautakunnat valtiollisina asiantuntijaeliminä ennen toista maailmansotaa
2012
Governance of cultural heritage: towards participatory approaches
2021
This article analyzes participatory governance in relation to heritage. Based on previous studies on the implementation of participation and theoretical discussions considering the participatory governance of cultural heritage, we found four types of cultural heritage governance, with differing weights with regard to public authorities, civil society, markets, and citizens. Governmental, corporatist, service-led, and co-creative cultural heritage governance types were identified, which reflect the shifts in participatory approaches to governance from state-centered activities to the proliferation of civil society, and from professionally dominated to more citizen-based activities. According…
Tra punizione e riparazione: una ibridazione di paradigmi?
2016
Halogen Bonds in 2,5-Dihalopyridine-Copper(I) Halide Coordination Polymers
2019
Two series of 2,5-dihalopyridine-Cu(I)A (A = I, Br) complexes based on 2-X-5-iodopyridine and 2-X-5-bromopyridine (X = F, Cl, Br and I) are characterized by using single-crystal X-ray diffraction analysis to examine the nature of C2&minus
Python moduļa izstrāde un integrācija tīmekļa operētājsistēmā webAppOS drošības funkcionalitātes nodrošināšanai
2022
Tīmekļa operētājsistēma webAppOS ir infrastruktūra, kas ietver sevī vairākus tīmekļa procesorus jeb moduļus, kas ļauj vienā tīmekļa lietotnē izsaukt klašu metodes, kas ir realizētas dažādas programmēšanas valodās. Šī darba mērķis ir izveidot Python moduli un ieintegrēt to webAppOS vidē. Modulis dos izstrādātājiem iespēju veidot klašu metodes Python programmēšanas valodā. Moduli ir paredzēts lietot drošības funkcionalitātes nodrošināšanai, tas ir, automātiskai HTTPS komunikācijas protokola sertifikātu ģenerēšanai un sistēmas mapju šifrēšanai. Šiem nolūkiem tiks izmantoti, attiecīgi, RSA un AES algoritmi, kas ļauj sasniegt augstu drošības līmeni, netērējot daudz resursu.
Rac1 and PAK1 are upstream of IKK-ε and TBK-1 in the viral activation of interferon regulatory factor-3
2004
The anti-viral type I interferon (IFN) response is initiated by the immediate induction of IFN beta, which is mainly controlled by the IFN-regulatory factor-3 (IRF-3). The signaling pathways mediating viral IRF-3 activation are only poorly defined. We show that the Rho GTPase Rac1 is activated upon virus infection and controls IRF-3 phosphorylation and activity. Inhibition of Rac1 leads to reduced IFN beta promoter activity and to enhanced virus production. As a downstream mediator of Rac signaling towards IRF-3, we have identified the kinase p21-activated kinase (PAK1). Furthermore, both Rac1 and PAK1 regulate the recently described IRF-3 activators, I kappa B kinase- and TANK-binding kina…
Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters
2002
In the present study, we addressed the question of a putative relevance of Rho proteins in tumour progression by analysing their expression on protein and mRNA level in breast tumours. We show that the level of RhoA, RhoB, Rac1 and Cdc42 protein is largely enhanced in all tumour samples analysed (n=15) as compared to normal tissues originating from the same individual. The same is true for 32P-ADP-ribosylation of Rho proteins which is catalysed by Clostridium botulinum exoenzyme C3. Also the amount of Rho-GDI and ERK2 as well as the level of overall 32P-GTP binding acvitity was tumour-specific elevated, yet to a lower extent than Rho proteins. Although the amount of Rho proteins was enhance…
An Endemic Plant of the Mediterranean Area: Phytochemical Characterization of Strawberry Tree (Arbutus unedo L.) Fruits Extracts at Different Ripenin…
2022
This work focused on the extraction, quantification, and characterization of bioactive compounds of Arbutus unedo L. fruits, comparing the results obtained from the different ripening states. Extractions were performed by different methods (such as maceration extraction and ultrasonic extraction) and food grade solvents (aqueous and hydroalcoholic solvents) in each of the all ripening states (four states considered, associated with four different colors, i.e., green, yellow, orange, and red). The presence of (poly)phenols was quantified and characterized, and scavenging activity was determined by the Folin–Ciocâlteu reagent and the DPPH method, respectively. The content of bioactive compoun…
Kulttuuritoiminta ja alueellinen erilaistuminen : kulttuuritoiminnan rahoitus Suomen kunnissa 2010-luvulla
2020
In Finland, cultural services have traditionally been developed as the services of the welfare state that are provided in every municipality. In the past few decades, new forms of governance, changing population structure and economic decline have affected municipalities’ operational environment. Simultaneously, the aims of cultural policy have increasingly broadened. This article examines how the municipal cultural services are financed in municipalities with different structural qualities and financial resources in Finland in the 2010s. peerReviewed