Search results for "RNAs"

The emerging role of miRNA-132/212 cluster in neurologic and cardiovascular diseases: Neuroprotective role in cells with prolonged longevity

2021

Abstract miRNA-132/212 are small regulators of gene expression with a function that fulfills a vital function in diverse biological processes including neuroprotection of cells with prolonged longevity in neurons and the cardiovascular system. In neurons, miRNA-132 appears to be essential for controlling differentiation, development, and neural functioning. Indeed, it also universally promotes axon evolution, nervous migration, plasticity as well, it is suggested to be neuroprotective against neurodegenerative diseases. Moreover, miRNA-132/212 disorder leads to neural developmental perturbation, and the development of degenerative disorders covering Alzheimer’s, Parkinson’s, and epilepsy’s …

El frau de l’alquimista en l’infern dantesc de Joan Pasqual i en la tradició medieval

2015

This article presents and analyses chapter XLVI from the Tractat de les penes particulars d’infern by Catalan franciscan friar Joan Pasqual, written soon after 1436. This chapter, “Del cercle de l’alquimia”, includes an exemplum which is doubly significant: on the one hand, it documents the alchemic legend in the Plantagenets’ court during the 14th and 15th centuries; on the other hand, and most importantly, it is a new testimony of two narrative motifs of Eastern origin: the fake alchemist and the king (Thompson, K.111.4; Tubach, 89), and the account-book of mistakes or fools (Thompson,J.1371). After introducing the medieval witnesses of these motifs, the alchemic legend of Ramon Llull and…

Regulation of microRNAs and their role in liver development, regeneration and disease

2013

Abstract Since their discovery more than a decade ago microRNAs have been demonstrated to have profound effects on almost every aspect of biology. Numerous studies in recent years have shown that microRNAs have important roles in development and in the etiology and progression of disease. This review is focused on microRNAs and the roles they play in liver development, regeneration and liver disease; particularly chronic liver diseases such as alcoholic liver disease, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, viral hepatitis and primary liver cancer. The key microRNAs identified in liver development and chronic liver disease will be discussed together with, where pos…

Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function

2014

Pathogen reduction (PR) systems for platelets, based on chemically induced cross-linking and inactivation of nucleic acids, potentially prevent transfusion transmission of infectious agents, but can increase clinically significant bleeding in some clinical studies. Here, we documented the effects of PR systems on microRNA and mRNA levels of platelets stored in the blood bank, and assessed their impact on platelet activation and function. Unlike platelets subjected to gamma irradiation or stored in additive solution, platelets treated with Intercept (amotosalen + ultraviolet-A [UVA] light) exhibited significantly reduced levels of 6 of the 11 microRNAs, and 2 of the 3 anti-apoptotic mRNAs (B…

Poetiche della musica nell'antichità e nel rinascimento

2008

Tramite Aristosseno, Dionigi d'Alicarnasso e Pietro Bembo la poestica dell'antica musica ellenica del V secolo a.C. viene trasmessa ai compositori del madrigale polifonico italiano del Rinascimento.

Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells.

2010

International audience; Resveratrol (trans-3,4',5-trihydroxystilbene) is a natural antioxidant with cardiovascular and cancer preventive properties that is currently at the stage of pre-clinical studies for human cancer prevention. Beside its known effects on protein coding genes, one possible mechanism for resveratrol protective activities is by modulating the levels of non-coding RNAs. Here, we analyzed the effects of resveratrol on microRNA populations in human SW480 colon cancer cells. We establish that resveratrol treatment decreases the levels of several oncogenic microRNAs targeting genes encoding Dicer1, a cytoplasmic RNase III producing mature microRNAs from their immediate precurs…

Apendektomijas epidemioloģija pēc Bērnu klīniskās universitātes slimnīcas datiem 2005. - 2015. gadā

2017

Pētījumā tika apskatīta tēma "Apendektomijas epidemioloģija pēc Bērnu klīniskās universitātes slimnīcas datiem 2005. - 2015. gadā”, analizēta bērnu akūta apendicīta saslimstība un to histoloģisku apakštipu izplatība. Pielietota retrospektīva analītiskā pētniecības metode. Teorētiskā daļa balstās uz 44 literatūras avotiem. Pētījumā izmantoti dati no 2279 nosūtījumiem uz patoloģisku izmeklēšanu no slimnīcas arhīva; papildus tiek analizētas materiāla histoloģiskās un imūnhistoķīmiskās pārmaiņas. Izveidota datubāze, veikta datu statistiskā apstrāde. Analīze pierādīja, ka bērnu saslimstība ar apendicītu ir samēra stabila un atkarīga no vecuma un dzimuma (prevalē zēni skolnieki); pārsvarā tiek iz…

Golden eagle, Águila real (VER0000161)

Altres noms vulgars: Golden eagle (Anglès), Aigle royal (Francès), Steinadler (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 4-2 Juvenil

Àguila reial, Águila real (VER0000222)

1871

Golden eagle (Anglès), Aigle royal (Francès), Steinadler (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 1-1 Villalonga 04/12/1871 Macho Adulto

Àguila reial, Águila real (VER0000223)

Golden eagle (Anglès), Aigle royal (Francès), Steinadler (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 6-1 Valencia Macho Adulto