Search results for "ROH"

showing 10 items of 730 documents

Regioselective Synthesis of Mono- and Dispiropyrazoline Derivatives via 1,3-dipolar Cycloaddition with Nitrilimines

2016

The 1,3-dipolar cycloaddition reaction of (E,E)-1,3-bis(arylidene)indan-2-one with diarylnitrilimines, generated in situ via dehydrohalogenation of the corresponding hydrazonoyl chlorides , affords predominantly monospiropyrazolines and as a mixture of diastereoisomers. Also dispiropyrazolines are formed in moderate yields. The structure and stereochemistry of cycloadducts were confirmed by 1H and 13C-NMR spectroscopy, elemental analyses data, and single-crystal X-ray diffraction studies of and .

010405 organic chemistryChemistryOrganic ChemistryDiastereomerRegioselectivity010402 general chemistry01 natural sciencesMedicinal chemistryCycloaddition0104 chemical sciences13-Dipolar cycloadditionDehydrohalogenationOrganic chemistrySpectroscopyJournal of Heterocyclic Chemistry
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Identification and expression analysis of theSpodoptera exiguaneuropeptidome under different physiological conditions

2018

Neuropeptides are small signalling molecules acting as neurohormones, neurotransmitters and neuromodulators. Being part of the chemical communication system between cells within an organism, they are involved in the regulation of different aspects of animal physiology and behaviour such as feeding, reproduction, development and locomotion. Transcriptomic data from larval and adult tissues have been obtained and mined to generate a comprehensive neuropeptidome for the polyphagous insect pest Spodoptera exigua. Sixty-three neuropeptides have been identified and described based on their tissue specificity and their regulation in response to different abiotic perturbations. Expression analyses …

0106 biological sciences0301 basic medicineAbiotic componentbiologymedia_common.quotation_subjectfungiMidgutInsectSpodopterabiology.organism_classification01 natural sciencesCell biologyTranscriptome010602 entomology03 medical and health sciences030104 developmental biologyInsect ScienceExiguaGeneticsNeurohormonesMolecular BiologyOrganismmedia_commonInsect Molecular Biology
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Transcriptome approach to understand the potential mechanisms inhibiting or triggering blossom-end rot development in tomato fruit in response to pla…

2017

The objectives of this study were to analyze changes in gene expression and identify candidate genes and gene networks potentially inhibiting or triggering blossom-end rot (BER) in tomatoes treated with plant growth regulators. ?Ace 55 (Vf)? tomato plants were grown in a greenhouse and sprayed with Apogee (300 mg L?1), abscisic acid (ABA) (500 mg L?1), water (control), or gibberellins 4?+?7 (GA4?+?7) (300 mg L?1) weekly after pollination. The BER incidence rate was zero in Apogee- and ABA-, medium in water-, and high in GA4?+?7-treated plants from 26 to 40 days after pollination (DAP). At 26 DAP, healthy blossom-end fruit tissue still not showing visible BER symptoms was used for transcript…

0106 biological sciences0301 basic medicineCandidate geneEstimulante de Crescimento VegetalPlant growth regulatorsPlant ScienceBiologymedicine.disease_cause01 natural sciencesGeneGiberelinaTranscriptome03 medical and health scienceschemistry.chemical_compoundAbscisic acidTomateSettore AGR/07 - Genetica AgrariaBotanyGene expressionmedicineDisorderGibberellinÁcido giberélicoHormônio VegetalAbscisic acidchemistry.chemical_classificationReactive oxygen speciesBERRegulador de crescimentofood and beveragesPlant physiologyHorticulture030104 developmental biologychemistryGibberellinProhexadione calciumAgronomy and Crop ScienceOxidative stress010606 plant biology & botanyProhexadione-calcium
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Lack of specialist nidicoles as a characteristic of mite assemblages inhabiting nests of the ground-nesting wood warbler, Phylloscopus sibilatrix (Av…

2021

AbstractBird and mammal nests provide microhabitats that support a range of other species, including invertebrates. However, the variation between communities of nest-dwelling invertebrates in different nests is poorly understood. The major aim of this study was to analyze the assemblage structure of mites from the suborder Uropodina (Acari: Mesostigmata) and from superfamily Crotonioidea (Acari: Oribatida) inhabiting nests of the wood warbler, Phylloscopus sibilatrix (Aves: Passeriformes), located on a forest floor in Białowieża Forest, in eastern Poland. We also assessed the correlation between the nest material used by the birds with the assemblage structure of Uropodina mites, and compa…

0106 biological sciencesZoology010603 evolutionary biology01 natural sciencesArticleEcology and EnvironmentUropodinaSongbirdsNestUnstable microhabitats · UropodinaMiteWood warblerAnimalsAcariPasseriformesOribatidaMitesEcologybiologyGeneral MedicineUnstable microhabitatsbiology.organism_classification010602 entomologyNest of birdsPlant BreedingAssemblage structureAnimal ecologyInsect ScienceCrotonioideaTalpaMesostigmataPoland
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Are there so many congeneric species of chironomid larvae in a small stream?

2018

The co-occurrence of larvae of congeneric chironomid species is common in natural stream assemblages, and raises the problem of finding mechanisms to explain the co-existence of species with similar ecological requirements. In this contribution, we explored the co-occurrence of chironomid larvae belonging to congeneric species within four genera of chironomids: Cricotopus, Eukiefferiella, Orthocladius and Rheocricotopus (with 2, 7, 2 and 4 species, respectively) in the headwaters of a small Mediterranean calcareous stream. Due to the intrinsic, natural spatial and temporal variability in these habitats, we studied three different sites at two different seasons within the annual hydrological…

0106 biological scienceshydraulicsZoology010501 environmental sciencesAquatic ScienceBiology01 natural sciencesMediterrània (Regió)ChironomidsRiversco-occurrencelcsh:Physical geographylcsh:Environmental sciencesCursos d'aigua0105 earth and related environmental sciencesWater Science and Technologylcsh:GE1-350Ecologymicrohabitat.Mediterranean RegionDiptera010604 marine biology & hydrobiologylcsh:Geography. Anthropology. Recreationnichelcsh:GDípterscongeneric specieslcsh:GB3-5030Chironomid larvaeJournal of Limnology
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Effects of local forest continuity on the diversity of fungi on standing dead pines

2018

Human-induced fragmentation affects forest continuity, i.e. availability of a suitable habitat for the target species over a time period. The dependence of wood-inhabiting fungi on landscape level continuity has been well demonstrated, but the importance of local continuity has remained controversial. In this study, we explored the effects of local forest continuity (microhabitat and stand level) on the diversity of wood-inhabiting fungi on standing dead trunks of Scots pine (Pinus sylvestris L.). We studied species richness and community composition of decomposers and Micarea lichens on 70 trunks in 14 forests in central Finland that differed in their state of continuity. We used dendrochr…

0106 biological sciencesmäntykelopuutPinus sylvestris L.Management Monitoring Policy and Law010603 evolutionary biology01 natural sciencesDecomposerPinus sylvestrisL.MicareaBOREAL FORESTSdecomposerEPIPHYTIC LICHENSmicrohabitat continuityLichenNature and Landscape ConservationFragmentation (reproduction)4112 ForestryHabitat fragmentationbiologyjäkälätEcologyWOOD-INHABITING FUNGISPECIES RICHNESSdead wood continuityCONIFEROUS FORESTSSOUTHERN SWEDENta1183metsäekologiaTaigaScots pineForestry15. Life on landta4112biology.organism_classificationPICEA-ABIESlahottajasienetbiodiversiteettistand continuityGeographyHABITAT FRAGMENTATIONHabitatta1181ECOLOGICAL CONTINUITYSpecies richnesstyynyjäkälätDANISH BEECH-FORESTS010606 plant biology & botanyForest Ecology and Management
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Out in the open : behavior’s effect on predation risk and thermoregulation by aposematic caterpillars

2020

Abstract Warning coloration should be under strong stabilizing selection but often displays considerable intraspecific variation. Opposing selection on color by predators and temperature is one potential explanation for this seeming paradox. Despite the importance of behavior for both predator avoidance and thermoregulation, its role in mediating selection by predators and temperature on warning coloration has received little attention. Wood tiger moth caterpillars, Arctia plantaginis, have aposematic coloration, an orange patch on the black body. The size of the orange patch varies considerably: individuals with larger patches are safer from predators, but having a small patch is beneficia…

0106 biological sciencesvaroitusväriZoologyAposematismBiology010603 evolutionary biology01 natural scienceseläinten käyttäytyminenIntraspecific competitiontäpläsiilikäsPredation03 medical and health sciencesParus majoraposematismStabilizing selectionCaterpillarArctia plantaginisPredatorEcology Evolution Behavior and Systematicslämmönsäätely030304 developmental biologyParus0303 health sciencesthermoregulationAcademicSubjects/SCI01330Original Articlestalitiainen15. Life on landThermoregulationbiology.organism_classificationmicrohabitat preferencesaalistuscolorAnimal Science and Zoology
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A Novel Solution for the Elimination of Mode Switching in Pump-Controlled Single-Rod Cylinders

2020

This paper concerns the stability issue of pump-controlled single-rod cylinders, known as mode switching. First, a review of the topic is provided. Thereafter, the most recently proposed solution for the elimination of mode switching is investigated and shown to result in unstable behavior under certain operating conditions. A theoretical analysis is provided demonstrating the underlying mechanisms of this behavior. Based on the analysis, a novel control strategy is proposed and investigated numerically. Proper operation and stability are demonstrated for a wide range of operating conditions, including situations under which the most recently proposed solution results in unstable behavior a…

0209 industrial biotechnologyControl and OptimizationMaterials science020209 energy02 engineering and technologyelectrohydraulic valvesStability (probability)020901 industrial engineering & automationlinear actuatorsControl theorylcsh:TK1001-18410202 electrical engineering electronic engineering information engineeringlcsh:TA401-492large inertia loadsLinear actuatorstabilitylcsh:Production of electric energy or power. Powerplants. Central stationsRange (mathematics)VDP::Teknologi: 500single-pump circuitsmode switching instabilityControl and Systems EngineeringoscillationsMode switchinglcsh:Materials of engineering and construction. Mechanics of materialsActuatorpump-controlled systemsActuators
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Succinate receptor mediates intestinal inflammation and fibrosis.

2018

Succinate, an intermediate of the tricarboxylic acid cycle, is accumulated in inflamed areas and its signaling through succinate receptor (SUCNR1) regulates immune function. We analyze SUCNR1 expression in the intestine of Crohn's disease patients and its role in murine intestinal inflammation and fibrosis. We show that both serum and intestinal succinate levels and SUCNR1 expression in intestinal surgical resections were higher in CD patients than in controls. SUCNR1 co-localized with CD86, CD206, and alpha-SMA(+) cells in human intestine and we found a positive and significant correlation between SUCNR1 and alpha-SMA expression. In human isolated fibroblasts from CD patients SUCNR1 expres…

0301 basic medicineAdultMaleAdolescentImmunologyMacrophage polarizationSuccinic Acid610 Medicine & healthProinflammatory cytokineReceptors G-Protein-Coupled03 medical and health sciencesMiceYoung Adult0302 clinical medicineImmune systemCrohn DiseaseFibrosismedicineImmunology and AllergyAnimalsHumansIntestinal MucosaFibroblastReceptorCells CulturedCD86InflammationMice Knockout2403 Immunologybusiness.industryMacrophagesmedicine.diseaseColitisFibrosisCitric acid cycleMice Inbred C57BLDisease Models Animal10219 Clinic for Gastroenterology and Hepatology030104 developmental biologymedicine.anatomical_structure2723 Immunology and AllergyCancer researchFemalebusiness030215 immunologyMucosal immunology
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M1 Macrophages Activate Notch Signalling in Epithelial Cells: Relevance in Crohn's Disease

2016

Background: The Notch signalling pathway plays an essential role in mucosal regeneration, which constitutes a key goal of Crohn's disease (CD) treatment. Macrophages coordinate tissue repair and several phenotypes have been reported which differ in the expression of surface proteins, cytokines and hypoxia-inducible factors (HIFs). We analysed the role of HIFs in the expression of Notch ligands in macrophages and the relevance of this pathway in mucosal regeneration. Methods: Human monocytes and U937-derived macrophages were polarized towards the M1 and M2 phenotypes and the expression levels of HIF-1α, HIF-2α, Jagged 1 (Jag1) and delta-like 4 (Dll4) were evaluated. The effects of macrophage…

0301 basic medicineAdultMaleJAG1FarmacologiaAdolescentEnterocyteColonNotch signaling pathwayBiologymucosal healing03 medical and health sciencesYoung AdultIntestinal mucosaCrohn DiseasemedicineMacrophageHumansHES1Intestinal MucosaRecte MalaltiesReceptors NotchMacrophagesGastroenterologyEpithelial CellsGeneral MedicineMiddle AgedHypoxia-Inducible Factor 1 alpha SubunitCoculture TechniquesCell biologyCrohn's disease030104 developmental biologymedicine.anatomical_structureAparell digestiu MalaltiesCase-Control StudiesImmunologyLeukocytes MononuclearCytokinesNotch signallingEnterocyte differentiationFemaleOriginal ArticleSignal transductionCaco-2 CellsHT29 CellsBiomarkersSignal Transduction
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