Search results for "ROLE"

showing 10 items of 1994 documents

Editorial Comment from Dr Michel to Expression and functional role of β3-adrenoceptors in the human ureter

2013

Functional roleUretermedicine.anatomical_structureExpression (architecture)business.industryUrologyMedicineβ3 adrenoceptorbusinessBioinformaticsInternational Journal of Urology
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Seabird influence on ecological processes in coastal marine ecosystems: An overlooked role? A critical review

2021

Abstract Seabirds are vital, but overlooked, components of coastal marine ecosystems and may connect the marine and terrestrial environment at a global scale, significantly contributing to inter-habitat connectivity and the provision of multiple ecosystem services. Although the ecological and functional role of birds in terrestrial areas, islands in particular, has been deeply studied since the last century, the same does not hold true for coastal marine areas. Given the importance of coastal areas for seabirds worldwide and, at the same time, the high vulnerability of both, looking into the role of seabirds in influencing the ecosystem functioning in coastal areas is needed nowadays. Here,…

Functional rolebiologyEcologyWadersVulnerabilityAquatic ScienceOceanographyAllochthonous inputEcosystem servicesGeographybiology.animalEcological functionsWaterbirdsEcosystem servicesTerrestrial ecosystemMarine ecosystemEcosystemSeabirdAquatic birdsTrophic levelEstuarine, Coastal and Shelf Science
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Phase matters: responding to and learning about peripheral stimuli depends on hippocampal θ phase at stimulus onset.

2015

Hippocampal θ (3–12 Hz) oscillations are implicated in learning and memory, but their functional role remains unclear. We studied the effect of the phase of local θ oscillation on hippocampal responses to a neutral conditioned stimulus (CS) and subsequent learning of classical trace eyeblink conditioning in adult rabbits. High-amplitude, regular hippocampal θ-band responses (that predict good learning) were elicited by the CS when it was timed to commence at the fissure θ trough (Trough group). Regardless, learning in this group was not enhanced compared with a yoked control group, possibly due to a ceiling effect. However, when the CS was consistently presented to the peak of θ (Peak group…

Functional roleoppiminenCognitive NeuroscienceHippocampal formationStimulus (physiology)ta3112HippocampusmemoryhippocampalCellular and Molecular NeuroscienceAnimalsTheta Rhythmta515learningResearchEye movementClassical conditioningConditioning EyelidPeripheralNeuropsychology and Physiological PsychologyEyeblink conditioningConditioningFemaleRabbitsPsychologyNeuroscienceLearningmemory (Cold Spring Harbor, N.Y.)
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Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogu…

2015

Two new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and indole units were both substituted by 7-azaindole moieties or one indole unit was replaced by a 6-azaindole portion, were efficiently synthesized. Compounds belonging to both series inhibited the growth of HCT-116 colorectal cancer cells at low micromolar concentrations, whereas they did not affect the viability of normal-like intestinal cells. A compound of the former series induced apoptosis, evident as externalization of plasma membrane phosphatidylserine (PS), and changes of mitochondrial trans-membrane potential, while blocking the cell cycle in G2/M phase. In contr…

G2 Phaseantiproliferative activitybis-indolyl alkaloidsStereochemistryPyridinesPharmaceutical ScienceNortopsentin analoguesthiazolyl-bis-pyrrolo [23-b]pyridinesVacuoleArticlechemistry.chemical_compoundDrug DiscoveryImidazoleHumansPyrrolesautophagic deathThiazolelcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Cell ProliferationIndole testMembrane Potential MitochondrialnortopsentinsDose-Response Relationship DrugMolecular Structureindolyl-thiazolyl-pyrrolo[23-c]pyridinesthiazolyl-bis-pyrrolo[23-b]pyridinesapoptosisPhosphatidylserineCell cycleHCT116 CellsSettore CHIM/08 - Chimica Farmaceuticaindolyl-thiazolyl-pyrrolo[23-<i>c</i>]pyridinesThiazoleslcsh:Biology (General)chemistryCytoplasmApoptosismarine alkaloidsthiazolyl-bis-pyrrolo [23-<i>b</i>]pyridinesMarine drugs
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Fault role in geological processes. Repeated changing of activity mode and magnitude from basin formation to mountain belt staking: the case of the S…

2010

GEOLOGICAL PROCESSES FAULT ROLE SICILIAN CHAIN
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Water chemistry and abiogenic methane content of a hyperalkaline spring related to serpentinization in the Argolida ophiolite (Ermioni, Greece)

2018

Abstract Hyperalkaline mineral springs related to active continental serpentinization are a theme of growing interest since they may contain significant amounts of abiotic gas and have important implications for energy resource exploration, subsurface microbiology and astrobiology. We report the discovery of a new hyperalkaline (pH∼12) spring issuing in the Agioi Anargyroi monastery at Ermioni (Greece), connected to serpentinization of peridotites of the Argolis ophiolite. Two water samples have been collected from separated springs and analysed for the chemical composition of major, minor and trace elements, and isotopic composition (2H and 18O) of water by IC, ICP-OES, ICP-MS and IRMS, an…

Gas geochemistry010504 meteorology & atmospheric sciencesStratigraphyEarth scienceGeochemistryAquifer010502 geochemistry & geophysicsOceanographyOphiolite01 natural sciencesMethanechemistry.chemical_compoundSpring (hydrology)HydrogeochemistryGeophysicChemical composition0105 earth and related environmental sciencesgeographyBiologic methane oxidationgeography.geographical_feature_categoryMineralSerpentinizationGeologyStable isotopeAbiogenic petroleum originGeophysicschemistryAbiogenic methaneAnaerobic oxidation of methaneEconomic GeologyGeologyMarine and Petroleum Geology
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The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion.

2019

1. Preamble : Hypercholesterolemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD) [1]. Increased levels of low density lipoprotein cholesterol (LDL-C) are associated with an increased risk of coronary heart disease (CHD) and many clinical trials have shown that reducing LDL-C levels significantly reduced the CHD and CVD risk [[2], [3], [4], [5]]. Thus LDL-C-lowering is the main approach for the management of cardiovascular disease. Current guidelines suggest LDL-C levels targets based on the individual CV risk; such targets can be achieved by several means, which include both lifestyle changes and pharmacological approaches [6], with statins being the cornerstone …

Gastrointestinal Diseases[SDV]Life Sciences [q-bio]Hypercholesterolemia/Self Medication030204 cardiovascular system & hematologyPharmacology03 medical and health sciencesFood-Drug Interactions0302 clinical medicinePlasma cholesterolBiotransformationDouble-Blind MethodChinese traditionalInternal MedicineRed yeast riceMedicineCytochrome P-450 CYP3AHumansMulticenter Studies as TopicProdrugs030212 general & internal medicineLovastatinMusculoskeletal DiseasesMedicine Chinese TraditionalExpert TestimonyComputingMilieux_MISCELLANEOUSBiotransformationRandomized Controlled Trials as TopicBiological ProductsClinical Trials as TopicMolecular StructureRyanodine receptorbusiness.industryGeneral Medicine3. Good healthCholesterol blood[SDV] Life Sciences [q-bio]CholesterolCardiovascular DiseasesExpert opinionDietary Supplementslipids (amino acids peptides and proteins)Hydroxymethylglutaryl-CoA Reductase InhibitorsCardiology and Cardiovascular Medicinebusiness
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Attitudes toward gay men and lesbians and their relationship with gender role beliefs in a sample of chilean university students

2012

ABSTRACT. This paper analyzes the relation between gender role beliefs and prejudice toward gay men and lesbians in Chile. Participants were Chilean university students (N = 283). Results indicate that men are more prejudiced than women and religious people are more prejudiced than non-religious people. On the other hand, gender role beliefs mediate sex differences in prejudice. The participants' more traditional gender role beliefs hold more negative attitudes toward gay men and lesbians. Men are more prejudiced than women, particularly in their attitudes toward gay men. In addition, sex differences in attitudes toward lesbians and gay men are mediated by gender role beliefs.

Gender StudiesReproductive MedicineSocial Psychologymedia_common.quotation_subjectPublic Health Environmental and Occupational HealthSample (statistics)DermatologyGender rolePrejudicePsychologySocial psychologymedia_common
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The spouse of the female manager: role and influence on the woman's career

2009

PurposeThis paper aims to examine the role of the spouse, specifically the husband, for the woman manager's career by focusing on the gender role construction between spouses, and the relationship of these roles to the woman's career.Design/methodology/approachThe topic was investigated within a Finnish context by analyzing the narratives of 29 female managers. A common feature among the women was their managerial position and extensive work experience. All the women had or had had one or more spouses in the course of their careers, and all but one were mothers, mostly of teenage or adult children.FindingsA typology distinguishing five types of spouses was constructed: determining, supporti…

Gender StudiesTypologySpouseBusiness Management and Accounting (miscellaneous)NarrativeContext (language use)Gender rolePsychologySocial psychologyWork experienceGender in Management: An International Journal
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Agents of change: Women in top management and corporate environmental performance

2020

International audience; We analyze the influence of gender diversity in top management on the environmental performance of French firms. Consistent with gender socialization theory, which posits that women are raised from childhood to be more nurturing and compassionate for others, we find that firms with more women in top management exhibit higher environmental performance. This result extends those already reported in the literature regarding the effect of gender diversity at board level. We also show that women in top management are associated with several key indicators such as development of eco‐friendly products and commitment to resource reduction. Furthermore, we find that the influ…

Gender diversityPerformanceStrategy and ManagementManagement Monitoring Policy and LawDevelopment0603 philosophy ethics and religionResource (project management)5. Gender equalitySustainable development11. Sustainability0502 economics and businessTop managementCSRGender diversitySustainable development05 social sciencesSocialization06 humanities and the artsRole theory[SHS.ECO]Humanities and Social Sciences/Economics and Finance13. Climate actionCorporate social responsibility[SHS.GESTION]Humanities and Social Sciences/Business administrationDemographic economicsTop management060301 applied ethicsBusiness050203 business & management
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