Search results for "ROMA"

showing 10 items of 13919 documents

The effect of exposure to radiofrequency fields on cancer risk in the general and working population: A protocol for a systematic review of human obs…

2021

Highlights • RF-EMF was classified by IARC as possibly carcinogenic to humans (2B) in May 2011 • A systematic review of all subject-relevant epidemiological studies is now needed. • A detailed protocol ensures the review's transparency, utility and credibility. • Original study validity will be evaluated with a customized OHAT risk of bias tool. • Internal coherence and external plausibility will inform conclusions.

Adultmedicine.medical_specialtyEpidemiologyRadio WavesMEDLINEBase stationsCase-control studiesPituitary tumoursBrain cancerRadiofrequency electromagnetic fieldsArticleElectromagnetic FieldsMeta-Analysis as TopicNeoplasmsEpidemiologymedicineSalivary gland tumoursLeukaemiaHumansMedical physicsMobile phonesGE1-350Internal validityBroadcast transmittersChildMicrowavesGeneral Environmental Sciencebusiness.industryBrain NeoplasmsAcoustic neuromaCase-control studyChildhood leukaemiaEnvironmental exposureGliomaEnvironmental ExposureOccupational exposureEnvironmental sciencesSystematic review protocolCohortCordless phonesCohort studiesObservational studybusinessMeningiomaCell PhoneCohort studyEnvironment International
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Effects of contralateral white noise stimulation on transitory evoked otoacoustic emissions in patients with acoustic neuroma.

1995

Abstract Transitory evoked otoacoustic emissions are normal phenomena observed in most persons with hearing levels greater than 35 dB. Further, masking of the contralateral ear produces amplitude reductions in the transitory evoked otoacoustic emissions. We have undertaken a study of transitory evoked otoacoustic emissions in 20 patients with acoustic neuroma. All patients were assessed for transitory evoked otoacoustic emissions bilaterally, with and without contralateral masking with white band noise at 40, 50, and 60 dB. We found that transitory evoked otoacoustic emissions were present in 30% of ears with tumor and that the presence of transitory evoked otoacoustic emissions is associat…

Adultmedicine.medical_specialtyHearing Loss SensorineuralAcoustic neuromaStimulationAmplitude reductionAudiologyVestibular NerveNeurons EfferentHearingotorhinolaryngologic diseasesMedicineHumansIn patientProspective StudiesAgedTumor sizebusiness.industryHead neckAuditory ThresholdNeuroma AcousticMiddle Agedmedicine.diseaseCochleaHair Cells Auditory OuterWhite bandOtorhinolaryngologyAcoustic StimulationEvoked Potentials AuditoryContralateral earSurgerysense organsbusinessNoisePetrous BoneOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
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Chromosomal aberrations in patients with primary biliary cirrhosis.

1990

Chromosomal aberrations in untreated lymphocyte cultures, bleomycin (BLM)-induced aberrations and sister chromatid exchanges (SCE) in the peripheral blood lymphocytes of 11 patients suffering from primary biliary cirrhosis (PBC) and 14 matched control individuals were analysed. The lymphocytes of the PBC patients had on average a lower mitotic index (2.3) compared with controls (3.5) in the untreated cultures. The mean baseline rate of aberrations of the cultured lymphocytes of the patients was 5.3 aberrations per 100 metaphases (%); this was significantly different (P = 0.0291) from that of the controls with a mean of 2.3%. In lymphocytes of the patients and controls, most of the aberratio…

Adultmedicine.medical_specialtyMitotic indexLymphocyteBiliary cirrhosisBiologyBleomycinGastroenterologychemistry.chemical_compoundBleomycinPrimary biliary cirrhosisInternal medicineGeneticsmedicineMitotic IndexSister chromatidsHumansLymphocytesGenetics (clinical)Cells CulturedAgedChromosome AberrationsLiver Cirrhosis BiliaryKaryotypeMiddle Agedmedicine.diseaseMolecular medicinemedicine.anatomical_structurechemistryKaryotypingImmunologyFemaleSister Chromatid ExchangeHuman genetics
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Myogenic temporomandibular disorders: Clinical systemic comorbidities in a female population sample

2016

Background Myogenic temporomandibular disorders (MTMD) frequently coexist with other clinical conditions in the same individual. In the last decades, several authors have analyzed these comorbidities looking for the origin of this overlapping. Objetives The aim of this study was to perform a comparative anaylisis between a group of patients with MTMD and a control group of dental patients without dysfunctional pathology to assess whether there are significant differences in the presence of systemic medical comorbidities between the two groups. Material and Methods Restrospective epidemiological analysis, based on medical questionnaires in a group of 31 patients, women, aged from 24 to 58 (a…

Adultmedicine.medical_specialtyPainDysfunctional familyComorbidityYoung Adult03 medical and health sciences0302 clinical medicineFacial PainSurveys and QuestionnairesInternal medicineEpidemiologymedicineHumansYoung adultGeneral DentistryPathologicalbusiness.industryResearchHeadache030206 dentistryMiddle AgedTemporomandibular Joint Disorders:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseComorbidityOrofacial Pain-TMJDOtorhinolaryngologyJoint painUNESCO::CIENCIAS MÉDICASPhysical therapyFemaleSurgerymedicine.symptomHeadachesbusiness030217 neurology & neurosurgeryTinnitusMedicina Oral Patología Oral y Cirugia Bucal
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Activation-Induced Rigidity in Neurologically and Cognitively Healthy Individuals Aged 18-90 Years: A Cross-Sectional Study.

2021

Background: Rigidity is a key clinical feature of Parkinson’s disease (PD), but in a very early phase of the disease it may be absent and can be enhanced through active movements of the arm contralateral to the one being tested. Objective: To evaluate in a large cohort of neurologically and cognitively healthy (NCH) subjects aged 18–90 years if activation-induced rigidity (AR) is present in all age classes, and if there are biological differences between subjects showing AR (AR+) and not showing AR (AR-). Methods: 2,228 NCH subjects categorized as young adult (18–44 years), adult (45–64 years), elderly (65–74 years), and old/oldest-old (75–90 years) were included in the analysis, and underw…

Adultmedicine.medical_specialtyParkinson's diseaseAdolescentCross-sectional studyAudiologylacunesProdromal phaseYoung AdultCellular and Molecular NeuroscienceLateral ventriclesCognitionAtrophyHumansMedicinehealthy aging subjectscaudate atrophyYoung adultAgedglobal cerebral atrophyAged 80 and overActivation-induced rigiditybusiness.industryBrainParkinson DiseaseMiddle Agedwhite matter hyperintensitiesmedicine.diseaseMagnetic Resonance ImagingHyperintensityCross-Sectional StudiesHealthy individualsSettore MED/26 - NeurologiaNeurology (clinical)Atrophybusiness
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Psychological assessment of patients with temporomandibular disorders: confirmatory analysis of the dimensional structure of the Brief Symptoms Inven…

2006

Abstract Objective This article analyzes the psychometric and structural properties of the Brief Symptoms Inventory 18 in a sample of patients with temporomandibular disorders (TMDs), given the convenience of a brief evaluation of distress in these patients. Methods Confirmatory factor analysis was carried out in a sample of 114 patients with TMDs. Two models were tested: the theoretical model with the original structure proposed—which considers three dimensions—and the empirical model obtained through the exploratory factor analysis initially carried out by Leonard R. Derogatis—which consists of the four-factor structure. Results Both models reached satisfactory indexes in confirmatory fac…

Adultmedicine.medical_specialtyPsychometricsAdolescentPersonality InventoryAnxietyModels PsychologicalSurveys and QuestionnairesmedicineHumansPsychological testingPsychiatrySomatoform DisordersAgedDepressionReproducibility of ResultsMiddle AgedTemporomandibular Joint Disordersmedicine.diseaseExploratory factor analysisConfirmatory factor analysisPsychiatry and Mental healthClinical PsychologyDistressAnxietymedicine.symptomPersonality Assessment InventoryPsychologySomatizationClinical psychologyJournal of psychosomatic research
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Sympathetic activity at rest and motor brain areas: FDG-PET study.

2008

Although recent studies identified brain areas which are involved in short term activation of the sympathetic nervous system, little is known about brain mechanisms which generate the individual variability of basal autonomic activity. In this fluorodeoxyglucose positron emission tomography study (FDG-PET), we aimed to identify brain regions, which covary with function parameters of the autonomic nervous system at rest. Therefore, FDG-PET (Siemens, Germany) was performed twice in 14 healthy resting subjects (7 m, 7 f; mean age 29.5 years) while different parameters of autonomic function were assessed simultaneously: Blood pressure, heart rate, power spectra of heart rate variability (HF/LF …

Adultmedicine.medical_specialtySympathetic nervous systemSympathetic Nervous SystemRestBlood PressureCellular and Molecular NeuroscienceMuscle toneNorepinephrineFluorodeoxyglucose F18Heart RateInternal medicineHeart ratemedicineHeart rate variabilityHumansAttentionChromatography High Pressure LiquidEndocrine and Autonomic SystemsBrainAutonomic nervous systemmedicine.anatomical_structureEndocrinologyBlood pressureGlucosePositron-Emission TomographyNeurology (clinical)Primary motor cortexRadiopharmaceuticalsPsychologyMotor cortexAutonomic neuroscience : basicclinical
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Modulation of oestrogen excretion profiles by adjuvant chemotherapy in pre- and postmenopausal breast cancer.

1985

Modulation of steroid status by conventional chemotherapy was studied in 31 breast cancer patients receiving CMF and in 31 age-matched breast cancer patients without any therapy, taken as controls. This was achieved through the study of oestrogen excretion profiles using previously identified parameters and referring not only to classical but also to the “other”, namely catechol and unusual, oestrogen metabolites. After CMF treatment the premenopausal patients exhibit a modified excretion pattern, mainly concerning a marked and significant reduction of classical oestrogens, as shown by pattern indices. Because there is evidence that oestriol metabolism is not markedly affected by CMF treatm…

Adultmedicine.medical_specialtyTime FactorschlormethineAdjuvant chemotherapymedicine.medical_treatmentBreast NeoplasmsBiochemistryestriolGas Chromatography-Mass SpectrometrySteroidExcretionEndocrinologyBreast cancerInternal medicineestradiolAntineoplastic Combined Chemotherapy ProtocolsmedicineestrogenHumansStage (cooking)CyclophosphamideChromatography High Pressure LiquidAgedbusiness.industryEstrogensMetabolismMiddle Agedmedicine.diseaseestroneEstrogens CatecholEndocrinologyMethotrexateMetabolic rateAdrenal CortexFemaleFluorouracilMenopausebusinessAfter treatmentJournal of steroid biochemistry
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Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)

2011

The clitoris contributes to the normal female sexual response cycle. A significance of cyclic guanosine monophosphate (GMP) has been assumed in the control of clitoral vascular smooth muscle. As only a few investigations on the physiology of the vascular and non-vascular clitoral tissue have been carried out, knowledge on the mechanisms controlling this particular female genital organ is still vague. It has been suggested that human clitoral corpus cavernosum smooth muscle is regulated by nitric oxide (NO)/cyclic GMP and related key enzymes, such as NO synthases (NOSs) and the phosphodiesterase type 5 (PDE5). The present study evaluated in the human clitoris, by means of immunohistochemistr…

Adultmedicine.medical_specialtyVascular smooth muscleStromal cellAdolescentNitric Oxide Synthase Type IIIUrologyClitorisBiologyEndothelial NOSSecond Messenger SystemsClitorisNitric oxideYoung Adultchemistry.chemical_compoundInternal medicineCyclic GMP-Dependent Protein KinasesmedicineHumansVimentinProtein kinase ACyclic GMPCyclic guanosine monophosphateCyclic Nucleotide Phosphodiesterases Type 5Cyclic Nucleotide Phosphodiesterases Type 2Immunohistochemistrymedicine.anatomical_structureEndocrinologychemistrycGMP-specific phosphodiesterase type 5FemaleInternational Journal of Impotence Research
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Influence of nerve branch of origin and extracanalicular extension of the tumor on hearing after middle fossa removal of vestibular schwannoma

2007

Neither nerve branch of origin nor extracanalicular (up to 1 cm) extension of a vestibular schwannoma (VS) influence the postoperative hearing outcome in patients operated via a middle cranial fossa (MCF) approach.To test whether the nerve branch of tumor origin and an extracanalicular, up to 1 cm, tumor extension influences hearing outcome after MCF VS surgery.This was a retrospective case review of 50 patients with postoperative pure-tone audiogram (PTA) performed later than 90 days after surgery. Twenty patients had a superior vestibular nerve (SVN) tumor and 27 patients had an inferior vestibular nerve (IVN) tumor. In three patients the nerve branch of origin of the VS could not be uneq…

Adultmedicine.medical_specialtyVestibular NerveSchwannomaMiddle cranial fossaCase reviewHearingotorhinolaryngologic diseasesmedicineHumansIn patientAgedRetrospective StudiesVestibular systemCranial Fossa Middlebusiness.industryAuditory ThresholdNeuroma AcousticGeneral MedicineAudiogramMiddle AgedPrognosisVestibular nervemedicine.diseaseMagnetic Resonance ImagingMiddle fossaSurgerymedicine.anatomical_structureOtorhinolaryngologyAudiometry Pure-ToneVestibule LabyrinthOtologic Surgical ProceduresbusinessBone ConductionFollow-Up StudiesActa Oto-Laryngologica
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