Search results for "ROMA"

showing 10 items of 13919 documents

Santi soldati nelle campagne siciliane. La vicenda di S. Nicone

2007

È analizzata la vicenda del Martyrium di S. Nicone, in riferimento ai riflessi storici dell’epoca di composizione, ed al contesto sociale del versante orientale della Sicilia in cui si svolgono le vicende di questo santo-soldato.

Agiografia Sicilia Tarda AntichitàSettore L-ANT/03 - Storia RomanaS. Nicone
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Modulation by 5-HT3 and 5-HT4 receptors of the release of 5-hydroxytryptamine from the guinea-pig small intestine.

1993

The effects of agonists and antagonists of 5-hydroxytryptamine (5-HT) receptors on the release of endogenous 5-HT from enterochromaffin cells were studied in the vascularly perfused isolated guinea-pig small intestine. The experiments were done in the presence of tetrodotoxin in order to exclude a neuronally mediated influence on 5-HT release. The 5-HT3 receptor agonist 2-methyl-5-HT increased 5-HT release, and this effect was antagonized by 1 nmol/l tropisetron. Nanomolar concentrations of tropisetron, MDL 72,222 and granisetron decreased 5-HT release. Ondansetron (0.1 and 1 mumol/l) did not modify 5-HT release. 5-Methoxytryptamine, BIMU8 and cisapride concentration-dependently inhibited 5…

AgonistMalemedicine.medical_specialtySerotoninmedicine.drug_classGuinea PigsStimulationTetrodotoxinBiologychemistry.chemical_compoundInternal medicineIntestine SmallmedicineEnterochromaffin CellsAnimalsIntestinal MucosaReceptorPharmacologyGeneral Medicinemusculoskeletal systemSerotonin Receptor AgonistsPerfusionEndocrinologychemistryMetitepineReceptors SerotoninAutoreceptorEnterochromaffin cellTropisetronFemaleSerotoninSerotonin Antagonistsmedicine.drugNaunyn-Schmiedeberg's archives of pharmacology
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Biochemical evidence that the atypical antipsychotic drugs clozapine and risperidone block 5-HT(2C) receptors in vivo.

2002

Clozapine and risperidone are two atypical antipsychotic drugs which bind, among other receptors, to 5-HT(2C) receptor subtypes. They inhibit the basal inositol phosphate production in mammalian cells expressing rat or human 5-HT(2C) receptors. This biochemical effect is indicative of inverse agonist activity at these receptors. There is evidence that 5-HT(2C) receptors are involved in the control of the activity of central dopaminergic system. Therefore, the effects of clozapine (5 mg/kg ip), risperidone (0.08 mg/kg ip) and of the typical antipsychotic haloperidol (0.1 mg/kg ip) were studied on the extracellular concentration of dopamine (DA) in the nucleus accumbens of chloral hydrate-ane…

AgonistMalemedicine.medical_specialtymedicine.drug_classDopamineMicrodialysisClinical BiochemistryAtypical antipsychoticPharmacologyToxicologyBiochemistryNucleus AccumbensRats Sprague-DawleyBehavioral NeuroscienceInternal medicinemedicineHaloperidolElectrochemistryReceptor Serotonin 5-HT2CAnimalsReceptorClozapineBiological Psychiatry5-HT receptorClozapineChromatography High Pressure LiquidPharmacologyRisperidoneChemistryRisperidoneTypical antipsychoticRatsEndocrinologyReceptors SerotoninHaloperidolSerotonin AntagonistsExtracellular Spacemedicine.drugAntipsychotic AgentsPharmacology, biochemistry, and behavior
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Synthesis and pharmacological characterization of beta2-adrenergic agonist enantiomers: zilpaterol.

2009

The beta-adrenergic agonist 1 (zilpaterol) is used as production enhancer in cattle. Binding experiments of separated enantiomers on recombinant human beta(2)-adrenergic and mu-opioid receptors and functional studies showed that the (-)-1 enantiomer accounts for essentially all the beta(2)-adrenergic agonist activity and that it exhibits less affinity toward the mu-opioid receptor than (+)-1, which is a mu-opioid receptor antagonist. X-ray crystallography revealed the absolute configuration of (-)-1 to be 6R,7R.

AgonistTrimethylsilyl CompoundsStereochemistrymedicine.drug_classZilpaterolAbsolute configurationBiological activityStereoisomerismPharmacologyAdrenergic beta-AgonistsReceptor antagonistCrystallography X-RayRecombinant Proteinschemistry.chemical_compoundchemistryDrug DiscoverymedicineMolecular MedicineHumansEnantiomerReceptorBeta (finance)Adrenergic beta-2 Receptor AgonistsChromatography High Pressure LiquidJournal of medicinal chemistry
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Progesterone increases basal 3',5'-cyclic adenosine monophosphate formation and down-regulates the agonist-induced inositol phosphates generation in …

1992

Whether the placenta is a target tissue for estrogens and progesterone, and their putative mechanism of action, is still a controversial question in the literature. The effect of progesterone and estradiol on 3′,5′-cyclic adenosine monophosphate (cAMP) and inositol phosphates generation in human term placenta was investigated. Placental explants were incubated in vitro for up to 48 h in the absence and in the presence of estradiol, progesterone or both steroids (0.1 μmol/l final concentration in all cases), and were stimulated with terbutaline, a β-adrenergic agonist, (0.1 mmol/l) or angiotensin II(1 μmol/l), The cAMP content was measured by a competitive protein binding assay, and the gene…

Agonistmedicine.medical_specialtymedicine.drug_classEndocrinology Diabetes and MetabolismInositol PhosphatesPlacentaDown-RegulationBiologychemistry.chemical_compoundEndocrinologyPregnancyInternal medicinePlacentamedicineCyclic AMPTerbutalineHumansCyclic adenosine monophosphateInositolInositol phosphateProgesteronechemistry.chemical_classificationLabor ObstetricEstradiolAngiotensin IIGeneral MedicineTrypan BlueChromatography Ion ExchangeAngiotensin IIEndocrinologymedicine.anatomical_structurechemistryEstrogenSecond messenger systemLactatesFemaleActa endocrinologica
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Concordiae Agrigentinorum sacrum res publica Lilybitanorum. Nessi reali e presunti tra Agrigentum e Lilybaeum, a proposito di Iside. Parte I. Agrigen…

2019

The discovery of a temple at Agrigento in the neinties of the last Century and the recent detection of a sacred building at Lilibeo should contribute, according with their discoverers, to fill the lack of evidences concerning the Isis cult between the East and West part of Sicily. In order to re-consider the data that should confirm these two interpretations, the aim of this contribution is to take in exam the first of these two cases, Agrigento, suggesting, with the necessary prudence, a different lecture. Rather than an alternative hypothesis this lecture would offer a contribution to the debate. Some considerations on the sacred building and its location next to the Forum as well as on t…

Agrigento Imperial cult Roman temples Roman Sicily Roman sculptureSettore L-ANT/07 - Archeologia Classica
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Cultura artistica, paesaggio urbano e modelli identitari ad Agrigentum

2018

Si riesamina la cultura figurativa e il paesaggio urbano della città tardo ellenistica e protoimperiale, decrittando il palinsesto culturale e le sovrapposizioni e interrelazioni sia riguardo ai modelli di riferimento sia riguardo alle asserzioni identitarie

Agrigento cityscape identità romanizzazione cultura figurativaSettore L-ANT/07 - Archeologia Classica
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La Casa II A o Casa del mosaico a rombi

2019

Una breve descrizione della Casa II A del quartiere ellenistico-romano di Agrigento A short description of the House II A of the Hellenistic-Roman Quartier in Agrigento

Agrigento domestic architecture of the hellenistic-roman period Roman SicilySettore L-ANT/07 - Archeologia ClassicaAgrigento architettura domestica ellenistico-romana Sicilia romana
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Abitare ad Agrigentum: riletture in corso dell’isolato II del Quartiere ellenistico-romano

2020

Si illustrano brevemente le problematiche attuali dell'indagine sul cd. Quartiere ellenistico-romano di Agrigento, focalizzando l'attenzione sull'isolato II. The current problems of the investigation into the Hellenistic-Roman district of Agrigento are briefly illustrated, focusing attention on block II.

Agrigentum abitazioni quartiere ellenistico-romanoSettore L-ANT/07 - Archeologia ClassicaAgrigentum dwellings Hellenistic-Roman quarter
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Commercianti di frodo: nuovi scenari economici

2011

Questo saggio propone una riflessione sulla contraffazione dei prodotti alimentari, sulle frodi alimentari e sulle "agromafie" facendo riferimento, in alcuni casi, a reati di natura economica, in altri a settori del mercato controllati dalla criminalità organizzata anche attraverso la presenza di colletti bianchi. Nella prima parte del lavoro verranno individuate le modalità d'azione della criminalità economica all'interno del mercato della contraffazione e delle frodi alimentari. Nella seconda parte, saranno proposti alcuni esempi di contraffazione e di frodi alimentari.

Agromafie contraffazione criminalità economica frodi alimentarli
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