Search results for "ROUGH"

showing 10 items of 1198 documents

SARS-CoV-2 vaccine response and rate of breakthrough infection in patients with hematological disorders

2022

Abstract Background The clinical efficacy of SARS-CoV-2 vaccines according to antibody response in immunosuppressed patients such as hematological patients has not yet been established. Patients and methods A prospective multicenter registry-based cohort study conducted from December 2020 to December 2021 by the Spanish transplant and cell therapy group was used to analyze the relationship of antibody response at 3–6 weeks after full vaccination (2 doses) with breakthrough SARS-CoV-2 infection in 1394 patients with hematological disorders. Results At a median follow-up of 165 days after complete immunization, 37 out of 1394 (2.6%) developed breakthrough SARS-CoV-2 infection at median of 77 …

*Pfizer-BioNTech BNT162b2Cancer ResearchCOVID-19 Vaccines*Hematological malignanciesAutologous stem cell transplantationAntibodies ViralBreakthrough SARS-CoV-2 infectionModerna mRNA-1273Cohort StudiesHematological malignancies*Moderna mRNA-1273Correlates of protection*VaccineHumansProspective StudiesVacunacióPfizer-BioNTech BNT162b2Molecular BiologyBNT162 Vaccine*Immunocompromised patients*Correlates of protectionSARS-CoV-2VaccinationHematologic diseasesCOVID-19Hematology*Breakthrough SARS-CoV-2 infectionHematologic DiseasesSARS-CoV-2 vaccinesAllogeneic stem cell transplantationVirusOncologyMalalties hematològiquesImmunocompromised patients*SARS-CoV-2 vaccines*Autologous stem cell transplantation*COVID-19Vaccine*Allogeneic stem cell transplantationJournal of Hematology & Oncology
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The influence of Cr and Ni doping on the microstructure of oxygen containing diamond-like carbon films

2021

Abstract Non-hydrogenated diamond-like carbon (DLC) films doped with metals and oxygen were deposited by direct current magnetron sputtering. The influence of chromium and nickel on the surface morphology, elemental composition, bonding structure, adhesion force, optical transmittance and nanohardness of the films was characterized by atomic force microscopy (AFM), energy dispersive X-ray spectroscopy (EDX), multi-wavelength Raman spectroscopy, UV–VIS–NIR spectrophotometry and nanoindenter. The surface roughness was reduced with the addition of Cr (7.4 at. %) or Ni (8.9 at. %) into DLC films. The EDX measurements indicated that the addition of Cr increased the oxygen content by ~37%, while …

010302 applied physicsMaterials scienceDiamond-like carbonDopingAnalytical chemistrychemistry.chemical_element02 engineering and technology021001 nanoscience & nanotechnologyCondensed Matter PhysicsMicrostructure01 natural sciencesSurfaces Coatings and FilmsChromiumNickelsymbols.namesakechemistry0103 physical sciencessymbolsSurface roughness0210 nano-technologyRaman spectroscopyInstrumentationCarbonVacuum
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Influence of surface topography on depth profiles obtained by Rutherford backscattering spectrometry

2000

A method for determining correct depth profiles from samples with rough surfaces is presented. The method combines Rutherford backscattering spectrometry with atomic force microscopy. The topographical information obtained by atomic force microscopy is used to calculate the effect of the surface roughness on the backscattering spectrum. As an example, annealed Au/ZnSe heterostructures are studied. Gold grains were observed on the surfaces of the annealed samples. The annealing also caused diffusion of gold into the ZnSe. Backscattering spectra of the samples were measured with a 2 MeV 4He+ ion beam. A scanning nuclear microprobe was used to verify the results by measuring backscattering fro…

010302 applied physicsMicroprobeMaterials scienceIon beamAnnealing (metallurgy)Analytical chemistryGeneral Physics and AstronomyHeterojunction02 engineering and technologyCondensed Matter::Mesoscopic Systems and Quantum Hall Effect021001 nanoscience & nanotechnologyRutherford backscattering spectrometry01 natural sciencesSpectral lineCondensed Matter::Materials Science0103 physical sciencesSurface roughness0210 nano-technologySpectroscopyJournal of Applied Physics
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Refractive index controlled by film morphology and free carrier density in undoped ZnO through sol-pH variation

2018

Abstract Zinc oxide thin films, prepared by the sol-gel process, were deposited on glass substrate using spin coating technique. The sol-pH effect on the optical parameters was studied for alkaline sol. The surface roughness was investigated by atomic force microscopy (AFM) and varied from 20 to 40 nm. The optical transmission measurements were carried out to evaluate the behavior of the extinction coefficient and the refractive index. An exponential decay of the refractive index ‘n’ as a function of wavelength was observed. The refractive index increases slightly when the pH increases to pH = 9.5 where it reaches its maximum. Beyond this value, it decreases sharply. This behavior has been …

010302 applied physicsSpin coatingMaterials scienceMorphology (linguistics)Analytical chemistry02 engineering and technologySubstrate (electronics)Molar absorptivity021001 nanoscience & nanotechnology01 natural sciencesAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsWavelength0103 physical sciencesSurface roughnessElectrical and Electronic EngineeringExponential decay0210 nano-technologyRefractive indexOptik
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Effect of surface disorder on the domain structure of PLZT ceramics

2017

ABSTRACTPb1-xLax(Zr0.65Ti0.35)1-x/4O3 (PLZT x/65/35) ceramics were studied by Piezoresponse Force Microscopy in order to understand the origin of domain structure as a function of La content. We show that the domain topology is mainly determined by the composition and grain size. The characteristic correlation length decreases with increasing La content, being sensitive also to the synthesis method. The behavior of the correlation length is linked to the macroscopic properties, showing a strong increase of disorder with La doping. The roughness exponent for the domain wall in PLZT 9/65/35 is close to 2/3 indicating 1D character of domain walls in relaxors.

010302 applied physicsSurface (mathematics)Materials scienceCondensed matter physicsDoping02 engineering and technology021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciencesGrain sizeElectronic Optical and Magnetic MaterialsDomain wall (magnetism)Piezoresponse force microscopyvisual_art0103 physical sciencesDomain (ring theory)Roughness exponentvisual_art.visual_art_mediumCeramic0210 nano-technologyFerroelectrics
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Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs)

2020

[Image: see text] Translational readthrough-inducing drugs (TRIDs) rescue the functional full-length protein expression in genetic diseases, such as cystic fibrosis, caused by premature termination codons (PTCs). Small molecules have been developed as TRIDs to trick the ribosomal machinery during recognition of the PTC. Herein we report a computational study to identify new TRID scaffolds. A pharmacophore approach was carried out on compounds that showed readthrough activity. The pharmacophore model applied to screen different libraries containing more than 87000 compounds identified four hit-compounds presenting scaffolds with diversity from the oxadiazole lead. These compounds have been s…

010405 organic chemistryChemistryOrganic ChemistryTranslational readthroughNonsense mutationHTVSnonsense mutationOxadiazoleBenzoxazoleRibosomal RNA01 natural sciencesBiochemistrySmall molecule0104 chemical sciencescystic fibrosis010404 medicinal & biomolecular chemistrychemistry.chemical_compoundBiochemistryDrug Discoverypremature termination codonsPharmacophoreDerivative (chemistry)Pharmacophore modeling
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The WISE 2000 and 2001 Field Experiments in Support of the SMOS Mission:Sea Surface L-Band Brightness Temperature Observations and Their Application …

2004

Camps, Adriano ... et al.-- 20 pages, 16 figures, 3 tables

010504 meteorology & atmospheric sciences0211 other engineering and technologiesWind02 engineering and technologySea stateAtmospheric sciences01 natural sciencesOceanographic techniquesWind waveSurface roughnessEmissivitySeawater14. Life underwaterElectrical and Electronic EngineeringRadiometry[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces environment021101 geological & geomatics engineering0105 earth and related environmental sciencesRemote sensingPhysics[SDU.OCEAN]Sciences of the Universe [physics]/Ocean AtmosphereRadiometerFoamsOcean wavesRemote sensingSea surface temperature13. Climate actionBrightness temperatureGeneral Earth and Planetary SciencesSMOS MissionSignificant wave height
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Evaluating roughness effects on C-band AMSR-E observations

2014

International audience; The usefulness of microwave remote sensing to retrieve near-surface soil moisture has already been demonstrated in many studies. However, obtaining high quality estimates of soil moisture is influenced by many effects from soil, vegetation and atmosphere; one of the key parameters is surface roughness. This research focusses on a semi-empirical method to evaluate the roughness effects from space borne observations. Global maps of roughness effects are evaluated at C-band from AMSR-E measurements.

010504 meteorology & atmospheric sciencesC band[SDE.MCG]Environmental Sciences/Global Changes0211 other engineering and technologiessoil surface roughnessAMSR-E02 engineering and technologySurface finish01 natural sciences13. Climate actionEnvironmental sciencesoil moisture[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing021101 geological & geomatics engineering0105 earth and related environmental sciencesRemote sensing2014 IEEE Geoscience and Remote Sensing Symposium
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Spatio-temporal patterns of thermal anomalies and drought over tropical forests driven by recent extreme climatic anomalies

2018

The recent 2015–2016 El Niño (EN) event was considered as strong as the EN in 1997–1998. Given such magnitude, it was expected to result in extreme warming and moisture anomalies in tropical areas. Here we characterize the spatial patterns of temperature anomalies and drought over tropical forests, including tropical South America (Amazonia), Africa and Asia/Indonesia during the 2015–2016 EN event. These spatial patterns of warming and drought are compared with those observed in previous strong EN events (1982–1983 and 1997–1998) and other moderate to strong EN events (e.g. 2004–2005 and 2009–2010). The link between the spatial patterns of drought and sea surface temperature anomalies in th…

010504 meteorology & atmospheric sciencesClimate ChangeEvent (relativity)0208 environmental biotechnologyMagnitude (mathematics)02 engineering and technologyForestsGlobal Warming01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyZona Tropical0105 earth and related environmental sciencesEl Nino-Southern OscillationTropical ClimateTemperatureArticlesBosque TropicalDroughts020801 environmental engineeringClimatologíaIndonesiaClimatologyAfricaEnvironmental scienceSeasonsENSOGeneral Agricultural and Biological SciencesBrazilPhilosophical Transactions of the Royal Society B: Biological Sciences
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Vegetation vulnerability to drought in Spain

2014

[EN] Frequency of climatic extremes like long duration droughts has increased in Spain over the last century.The use of remote sensing observations for monitoring and detecting drought is justified on the basis that vegetation vigor is closely related to moisture condition. We derive satellite estimates of bio-physical variables such as fractional vegetation cover (FVC) from MODIS/EOS and SEVIRI/MSG time series. The study evaluates the strength of temporal relationships between precipitation and vegetation condition at time-lag and cumulative rainfall intervals. From this analysis, it was observed that the climatic disturbances affected both the growing season and the total amount of vegeta…

010504 meteorology & atmospheric sciencesClimateGeography Planning and Development0211 other engineering and technologiesSPIGrowing seasonlcsh:G1-92202 engineering and technology01 natural sciencesSequíaVegetation coverTropical vegetationEarth and Planetary Sciences (miscellaneous)medicineTeledetecciónPrecipitation021101 geological & geomatics engineering0105 earth and related environmental sciencesSequíasMoistureDroughtÍndices meteorológicos de sequíaVegetaciónVegetation cover15. Life on landRemote sensingVegetation dynamicsAridGeography13. Climate actionClimatologyClimamedicine.symptomVegetation (pathology)lcsh:Geography (General)
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