Search results for "RSV"

showing 10 items of 25 documents

Temporal association between the influenza virus and respiratory syncytial virus (RSV): RSV as a predictor of seasonal influenza.

2016

SUMMARYEpidemiologists agree that there is a prevailing seasonality in the presentation of epidemic waves of respiratory syncytial virus (RSV) infections and influenza. The aim of this study is to quantify the potential relationship between the activity of RSV, with respect to the influenza virus, in order to use the RSV seasonal curve as a predictor of the evolution of an influenza virus epidemic wave. Two statistical tools, logistic regression and time series, are used for predicting the evolution of influenza. Both logistic models and time series of influenza consider RSV information from previous weeks. Data consist of influenza and confirmed RSV cases reported in Comunitat Valenciana (…

0301 basic medicineAdultMaleTime FactorsMultinomial logistic modelAdolescentEpidemiologyBinomial regression030106 microbiologyRespiratory Syncytial Virus InfectionsBiologyLogistic regressionmedicine.disease_causeVirusSeasonal influenza03 medical and health sciencesYoung AdultInfluenza HumanmedicineHumansChildEpidemicsAgedAged 80 and overInfant Newbornvirus diseasesInfantMiddle AgedOrthomyxoviridaeVirologyOriginal PapersInfectious DiseasesRespiratory syncytial virus (RSV)Logistic ModelsSpainChild PreschoolRespiratory Syncytial Virus HumanFemaleSeasonsEpidemiology and infection
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Jaunu alkilaizvietotu 4-fenil-2-pirolidonu sintēze un ķīmisko īpašību izpēte

2016

Jaunu alkilaizvietotu 4-fenil-2-pirolidonu sintēze un ķīmisko īpašību izpēte. Baškevičs V., darba vadītāji: Dr.chem. Maksims Vorona, asoc. prof. Anda Prikšāne. Bakalaura darbs. 32 lappuses, 18 attēli, 18 literatūras avoti. Latviešu valodā. Izstrādātas jaunas 5-alkilaizvietoto 4-fenil-2-pirolidonus iegūšanas metodes, izmantojot malonātu vai 2-fluormalonāta esteru Mihaela pievienošanu -alkil--nitrostirolam, kā arī nitroalkānu pievienošanu kanēļskābes metilesterim. Iegūtie starpprodukti tika hidrogenēti paaugstinātā spiedienā Reneja niķeļa katalizatora klātbūtnē, veidojot 5-alkil-4-fenil-3-karboksi-2-pirolidonu un 5-metil-4-fenil-3-fluoro-3-karboksi-2-pirolidona esterus, vai 5-alkil-4-fenil-…

5-ALKIL-4-FENIL-2-OKSOPIROLIDONS4-METIL-4-AMINO-3-FENIL-2-FLUORSVIESTSKĀBE4-ALKIL-4-AMINO-3-FENILSVIESTSKĀBE5-ALKIL-4-FENIL-3-FLUORO-2-OKSOPIROLIDONSMIHAEĻA REAKCIJAĶīmija
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N-acetyl-L-cysteine (NAC) inhibit mucin synthesis and pro-inflammatory mediators in alveolar type II epithelial cells infected with influenza virus A…

2011

64% of chronic obstructive pulmonary disease (COPD) exacerbations are caused by respiratory infections including influenza (strains A and B) and respiratory syncytial virus (RSV). They affect the airway epithelium increasing inflammatory and apoptosis events through mechanisms involving ROS generation, and induce the release of mucins from epithelial cells that are involved in the deterioration of the patient's health during the course of the disease. The antioxidant NAC has proved useful in the management of COPD reducing symptoms, exacerbations and accelerated lung function decline. It has been shown to inhibit influenza virus replication and to diminish the release of inflammatory and ap…

BiologyMucin 5ACmedicine.disease_causeVirus ReplicationBiochemistryp38 Mitogen-Activated Protein KinasesVirusCell LinePulmonary Disease Chronic ObstructivemedicineHumansInterleukin 8PhosphorylationPharmacologyA549 cellMucinNF-kappa BAcetylcysteineRespiratory Syncytial VirusesPulmonary AlveoliInfluenza B virusRespiratory syncytial virus (RSV)Viral replicationApoptosisInfluenza A virusImmunologyRespiratory epitheliumInflammation MediatorsBiochemical pharmacology
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Cost analysis of a vaccination strategy for respiratory syncytial virus (RSV) in a network model

2010

[EN] In this paper an age-structured mathematical model for respiratory syncytial virus (RSV) is proposed where children younger than one year old, who are the most affected by this illness, are specially considered. Real data of hospitalized children in the Spanish region of Valencia are used in order to determine some seasonal parameters of the model. Once the parameters are determined, we propose a complete stochastic network model to study the seasonal evolution of the respiratory syncytial virus (RSV) epidemics. In this model every susceptible individual can acquire the disease after a random encounter with any infected individual in the social network. The edges of a complete graph co…

Cost estimationbusiness.industryStochastic modellingDiseaseBiologyRespiratory syncytial virusmedicine.disease_causeVaccination strategyComputer Science ApplicationsVaccinationRespiratory syncytial virus (RSV)Network mathematical modelSusceptible individualModeling and SimulationModelling and SimulationStatisticsmedicineCost analysisProbability distributionArtificial intelligencebusinessMATEMATICA APLICADANetwork modelMathematical and Computer Modelling
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Evaluation of a multiplex reverse transcriptase PCR ELISA for the detection of nine respiratory tract pathogens.

2003

A multiplex reverse transcription (RT) polymerase chain reaction combined with a microwell hybridization assay (m-RT-PCR-ELISA) was previously developed to detect nine different microorganisms: enterovirus (EV), influenza virus type A (IVA) and type B (IVB), respiratory syncytial virus (RSV), parainfluenzavirus type 1 (PIV1) and type 3 (PIV3), adenovirus (AV), Mycoplasma pneumoniae (Mpn), Chlamydia pneumoniae (Cpn) in a single test. These organisms do not usually colonize the respiratory tract of humans, but, if present, it may be assumed they are involved in respiratory disease.The m-RT-PCR-ELISA was tested on (i) culture supernatants of unknown contents, (ii) by determining the analytical…

Enzyme-Linked Immunosorbent AssayBiologymedicine.disease_causeSensitivity and SpecificityRespirovirusMicrobiologyAdenoviridaeVirologyMultiplex polymerase chain reactionmedicineHumansMultiplexRespiratory Tract InfectionsEnterovirusObserver VariationRespiratory tract infectionsReverse Transcriptase Polymerase Chain ReactionReproducibility of ResultsVirologyReverse transcriptaseRespiratory Syncytial VirusesReverse transcription polymerase chain reactionInfluenza B virusInfectious Diseasesmedicine.anatomical_structureRespiratory syncytial virus (RSV)Influenza A virusDNA ViralEnterovirusRespiratory tractJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology
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Latvijas evaņģēliskā kristiešu draudze “Kristus Pasaulei”

2020

Bakalaura darbs ir veltīts Latvijas evaņģēliskās kristiešu draudzes “Kristus Pasaulei” izpētei. Būtībā darbs ir lauka pētījums, kura mērķis bija pierādīt, ka Draudze ir attiecināma uz “Trešā viņa” pentakostāļiem. Pētījuma gaitā iegūtie dati ir apkopoti divās darba daļās. Pirmajā daļā “Trīs viļņi” ir apskatīti trīs pentakostāļu atzari, to vēsture, teoloģija un pamatiezīmes. Otrā daļa ir veltīta evaņģēlisko kristiešu draudzes “Kristus Pasaulei” vēstures, teoloģijas un prakses izklāstam un analīzei. Bakalaura darba nobeigumā ir apkopota iegūtā informācija un veikti secinājumi, kas apstiprina tēzi.

Kristus Pasauleitrešā viļņa pentakostāļiNeo-harizmātiTeoloģija un reliģiju zinātneVasarsvētku draudzes
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SARS CoV2 infection _The longevity study perspectives

2021

Graphical abstract

MaleAgingssRNA single-stranded RNARFLP restriction fragment length polymorphismHSPs heat shock proteinsReviewPTMs post-translational modificationsSevere Acute Respiratory SyndromeBiochemistryHIV-1 human immunodeficiency virus-1TNF-α tumor necrosis factor-αEC endothelial cells0302 clinical medicineFluAV influenza A virusI insertionMedicineIFN-γ interferon-γDIC disseminated intravascular coagulationPCR Polymerase Chain Reactionmedia_commonAged 80 and overLongevityRBD receptor-binding domainNeurologyLongevity modelMI myocardial infarctionNK natural killerhPIV2 human parainfluenza virus type 2media_common.quotation_subjectResearching genetic basis of resistance and potential pharmacological targetsLongevityDBP diastolic blood pressureNF-Kb nuclear transcription factor kBRANTES regulated upon activation normal T cell expressed and secretedMphi human macrophages03 medical and health sciencesCox 2 cyclooxygenase 2ORF open reading framePT prothrombin timeSettore MED/05 - Patologia ClinicaHumansMolecular BiologyInflammatory genesARDS acute respiratory distress syndromeNO nitric oxideD deletionCpGIs CpG islandsT2DM type 2 diabetes mellitusmedicine.diseaseFDP fibrin degradation products030104 developmental biologySARS CoV2 severe acute respiratory syndrome Coronavirus 2 virusImmunologyBMI body max indexItalian nonagenarians/centenariansRSV respiratory syncytial virusComplication030217 neurology & neurosurgeryMAPK mitogen-activated protein kinaseIP-10 IFN-γ -Inducible Protein 1040301 basic medicineAT1R activity of angiotensin 1 receptorsDCs dentritic cellsSSCP single strand conformation polymorphismACE/DD polymorphism of the angiotensin converting enzymeFGF21 fibroblast growth factor 21TLR4 toll-like receptor 4NAD nicotinamide adenine dinucleotideACE angiotensin-I converting enzymeAT2R activity of angiotensin 2 receptorsCOVID-19 Coronavirus disease 2019Respiratory distressACE2 angiotensin converting enzyme 2MKP-1 mitogen-activated protein kinase phosphatase-1 ()PD protease domainSNP single nucleotide polymorphismEH essential hypertensionTNFR tumor necrosis factor receptorINR international normalized ratio of the prothrombin timePAI-1 plasminogen activator inhibitor-1Ang angiotensinLPS lipopolysaccharideMCP1 monocyte chemoattractant protein-1medicine.symptomaPTT partial thromboplastin timeBiotechnologyDUSP1 dual specificity phosphatase 1Coronavirus disease 2019 (COVID-19)PC prostate cancerRAS renin-angiotensin aldosterone systemCCR5Δ32 genetic variant of chemokine receptorCOVID-19 Researching genetic basis of resistance and potential pharmacological targets Italian nonagenarians/centenarians Longevity modelAsymptomaticSARS-1 severe acute respiratory syndrome virus 1SIRT-1 Sirtuin 1Th1 t-helper lymphocyte type 1Immune systemROS reactive oxygen speciesTGF-β transforming growth factor betaET-1 endothelin-1ComputingMethodologies_COMPUTERGRAPHICSADAM-17 metallopeptidase domain 17business.industrySARS-CoV-2SBP systolic blood pressureCOVID-19HDACs histone deacetylasesComorbidityImmune Systembusiness5-LO lipoxygenase 5Ageing Research Reviews
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Respiratory syncytial virus infection in a Sicilian pediatric population: Risk factors, epidemiology, and severity

2008

Respiratory syncytial virus (RSV) is the leading cause of hospitalization for lower respiratory tract infections (LRTIs) in young children worldwide. This study evaluated the epidemiological and clinical patterns of RSV infection in infants hospitalized for LRTIs in Sicily. Over a 7-month period (October 1, 2005 to April 30, 2006), all children 6 months old, with a gestational age (GA) of >36 weeks, with a birth weight of >2.50 g, with previous hospitalizations due to LRTI, with smokers in the household, and with a history of breast-feeding (p < 0.05 for each). RSV infection was associated with a higher likelihood to be admitted to neonatal intensive care units and to longer hospitalization…

MalePulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtySettore MED/17 - Malattie InfettiveBirth weightRespiratory Syncytial Virus InfectionsTobacco smokeVirusSettore MED/38 - Pediatria Generale E SpecialisticaRisk FactorsIntensive careEpidemiologymedicineHumansBreast-feeding Hospitalization Infants Risk factors RSV infection Severity Trend seasonalImmunology and AllergyRespiratory systemSicilyRespiratory tract infectionsbusiness.industryInfant NewbornInfantGestational ageGeneral MedicineLogistic ModelsRespiratory Syncytial Virus HumanFemalebusinessAllergy and Asthma Proceedings
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Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

2011

Mitochondrial dysfunction and oxidative stress occur in Parkinson’s disease (PD), but little is known about the molecular mechanisms controlling these events. Peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α) is a transcriptional coactivator that is a master regulator of oxidative stress and mitochondrial metabolism. We show here that transgenic mice overexpressing PGC-1α in dopaminergic neurons are resistant against cell degeneration induced by the neurotoxin MPTP. The increase in neuronal viability was accompanied by elevated levels of mitochondrial antioxidants SOD2 and Trx2 in the substantia nigra of transgenic mice. PGC-1α overexpression also protected against MP…

MaleSOD2Mice TransgenicSubstantia nigraMitochondrionBiologyNeuroprotectionCell LineMiceCellular and Molecular Neurosciencechemistry.chemical_compoundDopaminemedicineAnimalsNeurotoxinParkinson Disease SecondaryMolecular BiologyPGC-1α RSV SIRT1 MPTP Dopaminergic neurons Parkinson’s diseasePharmacologyMPTPDopaminergicBrainParkinson DiseaseCell BiologyPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaMitochondriaCell biologyDisease Models AnimalOxidative Stressnervous systemBiochemistrychemistry1-Methyl-4-phenyl-1236-tetrahydropyridineTrans-ActivatorsMolecular MedicineFemaleTranscription Factorsmedicine.drugCellular and Molecular Life Sciences
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Involvement of estrogen receptors in the resveratrol-mediated increase in dopamine transporter in human dopaminergic neurons and in striatum of femal…

2011

Treatment with resveratrol (RSV) has been shown to protect vulnerable neurons after various brain injuries and in neurodegenerative diseases. The mechanisms for the effects of RSV in brain are not fully understood, but RSV may affect the expression of various gene products. RSV is structurally related to the synthetic estrogen, diethylstilbestrol so the effects of RSV may be gender-specific. Here we studied the role of RSV in the regulation of dopamine transporter (DAT) in the striatum using male and female mice. The basic levels of DAT in the striatum showed no sex difference, but the levels increased significantly by RSV (20 mg/kg i.p.) in female but not in male mice. Pretreatment of mice…

Malemedicine.medical_specialtyvirusesEstrogen receptorStriatumResveratrolCell Line03 medical and health sciencesCellular and Molecular Neurosciencechemistry.chemical_compoundMice0302 clinical medicineSex FactorsInternal medicineDopaminergic CellStilbenesmedicineAnimalsHumansReceptorFulvestrantCells Cultured030304 developmental biologyDopamine transporterPharmacology0303 health sciencesDopamine Plasma Membrane Transport ProteinsbiologyEstradiolDopaminergic NeuronsDopaminergicEstrogen Antagonistsvirus diseasesrespiratory systemAntiestrogenCorpus StriatumEndocrinologynervous systemchemistryReceptors EstrogenResveratrolbiology.proteinFemaleRSV Striatum Dopaminergic neuronsDAT Antiestrogen Gene expression030217 neurology & neurosurgeryNeuropharmacology
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