Search results for "RULE"
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Spatiotemporal and gender‐specific parasitism in two species of gobiid fish
2018
Abstract Parasitism is considered a major selective force in natural host populations. Infections can decrease host condition and vigour, and potentially influence, for example, host population dynamics and behavior such as mate choice. We studied parasite infections of two common marine fish species, the sand goby (Pomatoschistus minutus) and the common goby (Pomatoschistus microps), in the brackish water Northern Baltic Sea. We were particularly interested in the occurrence of parasite taxa located in central sensory organs, such as eyes, potentially affecting fish behavior and mate choice. We found that both fish species harbored parasite communities dominated by taxa transmitted to fish…
Atgremotāju un vides Listeria innocua izolātu ģenētiskais raksturojums un invāzijas izvērtējums in vitro.
2021
Silva Gradovska (2021): Atgremotāju klīniskā materiāla un vides Listeria innocua izolātu ģenētiskais raksturojums un invāzijas izvērtējums in vitro. Listeria ģints baktērijas ir vidē plaši sastopami mikroorganismi, no kuriem Listeria monocytogenes un L. ivanovii spēj ierosināt listeriozi. Patogenitātes ziņā mazāk pētītā L. innocua ir Gram-pozitīva vides baktērija, kas ir radniecīga L. monocytogenes. Darba mērķis bija novērtēt L. innocua izplatību vidē un raksturot to kā iespējamo patogēnu, analizējot L. innocua izolātus, kas iegūti no 27 saimniecības fermu vides un atgremotāju abortiem, genoma līmenī. Darbā visiem L. innocua izolātiem ir identificēta atsevišķu virulences gēnu klātbūtne un n…
Data from: Impact of host nutritional status on infection dynamics and parasite virulence in a bird-malaria system
2013
1. Host resources can drive the optimal parasite exploitation strategy by offering a good or a poor environment to pathogens. Hosts living in resource-rich habitats might offer a favourable environment to developing parasites because they provide a wealth of resources. However, hosts living in resource-rich habitats might afford a higher investment into costly immune defences providing an effective barrier against infection. Understanding how parasites can adapt to hosts living in habitats of different quality is a major challenge in the light of the current human-driven environmental changes. 2. We studied the role of nutritional resources as a source of phenotypic variation in host exploi…
Characterizing the bacterial fish pathogen Flavobacterium columnare, and some factors affecting its pathogenicity
2010
Flavobacterium columnare is a bacterial pathogen of fresh water fish causing lethal columnaris disease worldwide. At Finnish fish farms, columnaris disease has occurred since the early 1980s, and is a serious problem in salmonid farming in Finland. Currently, the only effective treatment is with antibiotics. Factors related to the pathogenicity of F. columnare, transmission of columnaris disease and the immunity of salmonids to columnaris infections are poorly known. F. columnare strains isolated from Finnish fish farms were characterized geno- and phenotypically, virulence and transmission experiments were conducted, and the efficacy of two immunostimulants against columnaris infections in…
Iron and virulence in the zoonotic pathogen Vibrio vulnificus
2014
Vibrio vulnificus es un patógeno humano emergente que es autóctono de ecosistemas acuáticos salobres de climas templados, tropicales y subtropicales. La especie se subdivide en 3 biotipos (Bt), de los cuales el Bt2 contiene un grupo de cepas que, además de poder infectar al hombre, pueden causar infecciones en peces. Este grupo es un complejo clonal serológicamente homogéneo que denominamos serovar E o serovar zoonótica (VvBt2SerE). Como patógeno humano, VvBt2SerE causa casos esporádicos de infecciones graves en heridas que pueden derivar en septicemia secundaria en pacientes inmunocomprometidos y como patógeno de peces, brotes o epizootias de una septicemia hemorrágica conocida como vibrio…
Vaginal infection of mice with HSV type 2 variant ER−: A new animal model for human primary genital HSV type 2 infections
1992
Abstract Studying the pathogenesis of vaginal infections in mice with two variants of Herpes simplex virus type 2 (HSV-2) strain ER we observed that both variants ER+ and ER− caused severe vaginitis but only ER+ invaded the CNS leading to lethal neurological disease. In contrast, mice infected with ER− cleared the virus from the vagina and recovered from infection. ER+ and ER− expressed equal levels of thymidine kinase (TK) indicating a TK-independent difference in neurovirulence. Using the non-neurovirulent variant ER−, we were able to investigate humoral immune responses late after infection. Vaginal infection with ER− suppressed serum antibody formation after a secondary systemic HSV-1 i…
Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations.
2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents the most severe global health crisis in modern human history. One of the major SARS-CoV-2 virulence factors is nonstructural protein 1 (Nsp1), which, outcompeting with the binding of host mRNA to the human ribosome, triggers a translation shutdown of the host immune system. Here, microsecond-long all-atom simulations of the C-terminal portion of the SARS-CoV-2/SARS-CoV Nsp1 in complex with the 40S ribosome disclose that SARS-CoV-2 Nsp1 has evolved from its SARS-CoV ortholog to more effectively hijack the ribosome by undergoing a critical switch of Q/E158 and E/Q159 residues that perfects Nsp1's interactions…
La progettazione di interventi per il benessere individuale e di comunità
2022
I progetti di intervento in ambito sociale e psicologico prevedono azioni volte a creare una rete non solo tra istituzioni e supporto informale, ma anche un'opportunità di cambiamento per i beneficiari. In tal senso, nel 2020, 6 giovani dei Servizi della Giustizia Minorile di Palermo hanno par-tecipato ad un progetto ottenendo un'opportunità di cambiamento attraverso la promozione del benessere, sia come individui sia come membri di una comunità. In generale, tali interventi consistono nel sostenere le categorie sociali e gli individui più vulnerabili. L'adozione dello sport acquatico è una metodologia valida, poiché si basa sulla condivisione di norme oltre che sulla responsabilità individ…
The role of the agreement as a tool for management of property relations in cases of cross border marriages and civil unions/partnerships registered …
2021
The essay examines the role of the agreement as a tool for managing property relationships in crossborder marriages and registered partnerships, in light of EU Regulations 1103 and 1104 of 2016, on the property regimes of international married or registered couples. The main prerogative of such acts is the recognition of the parties? freedom to choose the court and the applicable law. The law governing the matrimonial property regimes, or the property consequences of registered partnerships, has universal scope. This agreement in the form envisaged, which is backed by the need for legal certainty and predictability of the applicable rules, means that the spouses, in family problems which ha…
Zasada fair play a edukacja rodzinna
2017
Artykuł przedstawia relację pomiędzy sportową zasadą fair play a edukacją rodzinną. Podkreśla wartość sportowej normy pośród ogólnych zasad wychowania, wartość wychowawczą przykładów działania fair play oraz potrzebę budowania zdrowych relacji w rodzinie poprzez „czysty sport”. Rodzina jest środowiskiem właściwym dla kształtowania osoby ludzkiej. To w rodzinie wykuwa się najgłębsze postawy życiowe, uczy się odpowiedzialnego korzystania z wolności i tutaj zazwyczaj najlepiej rozwija się osobowość. Edukacja rodzinna korzysta z wypoczynku, rekreacji i sportu jako środków do realizacji celów i zadań wychowawczych. Proces dobrze rozumianej edukacji rodzinnej poprzez sport dokonuje się w przestrz…