Search results for "RULE"

showing 10 items of 1403 documents

Utilization of hemin and hemoglobin by Vibrio vulnificus biotype 2

1996

The eel pathogen Vibrio vulnificus biotype 2 is able to use hemoglobin (Hb) and hemin (Hm) to reverse iron limitation. In this stud, the adjuvant effect of both compounds on eel pathogenicity has been evaluated and confirmed. Further, we have studied the heme-iron acquisition mechanism displayed by this bacterium. Whole cells were capable of binding Hb and Hm, independently of (i) iron levels in growth medium and (ii) the presence of polysaccharide capsules on bacterial surface. The Hb- and Hm-binding capacity was retained by the outer membrane protein (OMP) fraction and was abolished after proteolytic digestion of OMP samples. Western blotting (immunoblotting) of denatured OMPs revealed th…

IronVibrio vulnificusApplied Microbiology and BiotechnologyMicrobiologyHemoglobinschemistry.chemical_compoundVibrionaceaeAnimalsHemeVibrioEelsVirulenceEcologybiologyProteolytic enzymesbacterial infections and mycosesbiology.organism_classificationVibriochemistryBiochemistryHeminbacteriaHemoglobinCarrier ProteinsBacterial outer membraneBacterial Outer Membrane ProteinsResearch ArticleFood ScienceBiotechnologyHeminApplied and Environmental Microbiology
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Role of iron in the pathogenicity of Vibrio damsela for fish and mammals.

1994

The ability to obtain iron of 14 isolates of Vibrio damsela with different degrees of virulence for mice and turbot (Scophthalmus maximus) has been evaluated in artificial and natural iron-restricted environments. All strains were capable of utilizing haemoglobin (Hb) and ferric ammonium citrate (FAC) as the sole iron sources in vitro. However, only virulent V. damsela strains were able to resist the bacteriostatic and bactericidal effects of human and turbot sera, their growth being enhanced by the addition of Hb and FAC. The inhibitory effect of these sera on the growth of the non-pathogenic strain (ATCC 35083), however, was reversed by heat treatment (56 degrees C for 60 min). The role o…

IronVirulenceMicrobiologyFerric CompoundsMicrobiologyHeatingHemoglobinsMiceVibrionaceaeGeneticsmedicineAnimalsHumansMolecular BiologyCells CulturedVibrioMice Inbred BALB CbiologyStrain (chemistry)Virulencebiology.organism_classificationIn vitroScophthalmusTurbotQuaternary Ammonium CompoundsVibrio InfectionsFlatfishesFerricBacteriamedicine.drugFEMS microbiology letters
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<p>Isolation and Functions of Extracellular Vesicles Derived from Parasites: The Promise of a New Era in Immunotherapy, Vaccination, and Diagno…

2020

Experimental and epidemiological evidence shows that parasites, particularly helminths, play a central role in balancing the host immunity. It was demonstrated that parasites can modulate immune responses via their excretory/secretory (ES) and some specific proteins. Extracellular vesicles (EVs) are nano-scale particles that are released from eukaryotic and prokaryotic cells. EVs in parasitological studies have been mostly employed for immunotherapy of autoimmune diseases, vaccination, and diagnosis. EVs can carry virulence factors and play a central role in the development of parasites in host cells. These molecules can manipulate the immune responses through transcriptional changes. Moreo…

Isolation (health care)medicine.medical_treatmentBiophysicsPharmaceutical ScienceVirulenceBioengineering02 engineering and technologyBiology010402 general chemistry01 natural sciencesExtracellular vesiclesBiomaterialsImmune systemImmunityDrug DiscoverymedicineOrganic ChemistryGeneral MedicineImmunotherapy021001 nanoscience & nanotechnologybiology.organism_classification0104 chemical sciencesVaccinationImmunologyProtozoa0210 nano-technologyInternational Journal of Nanomedicine
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DYNAMIC SEMANTIC USER PROFILING FROM IMPLICIT WEB NAVIGATION DATA

2014

International audience; On the Web, pages are often dynamically generated and allow publishers to individually adapt contents to each viewer. Underlying systems must correctly understand the user's context - crucial especially in the case of online advertisement placement. The article at hand describes our proposition of a novel profiling system, adapted to the special needs of digital advertising. Based on Semantic Web Technologies, the MindMinings system relies on an ontology to enable thorough understanding of each user's context and needs. The underlying ontology structure also provides enhanced interoperability with semantically annotated knowledge resources, notably vocabularies from …

JEL classification: M37 Advertising; L86 Information and Internet Services Computer Software; D80 General (Information Knowledge Uncertainty)Web Analysis[INFO.INFO-CL] Computer Science [cs]/Computation and Language [cs.CL]Rule-based reasoningOntologiesUser Profiling[ INFO.INFO-CL ] Computer Science [cs]/Computation and Language [cs.CL][INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL]Semantic Web
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Simple Facts Concerning Nambu Algebras

1998

A class of substitution equations arising in the extension of Jacobi identity for $n$-gebras is studied and solved. Graded bracket and cohomology adapted to the study of formal deformations are presented. New identities in the case of Nambu-Lie algebras are proved. The triviality in the Gerstenhaber sense of certain deformed n-skew-symmetric brackets, satisfying the Leibniz rule with respect to a star-product, is shown for n≥ 3.

Jacobi identityClass (set theory)CommutatorSubstitution (algebra)Statistical and Nonlinear PhysicsTrivialityCohomologyAlgebrasymbols.namesakeLeibniz integral ruleSimple (abstract algebra)symbolsMathematical PhysicsMathematicsCommunications in Mathematical Physics
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Jueces y «control de calidad» de los sistemas políticos

2007

Maria.J.Anon@uv.es Este artículo trata de analizar la tesis normativa que atribuye a los jueces la función de garantía de la estabilidad de los sistemas políticos, examen que se lleva a cabo en dos planos. En primer lugar, realizo una valoración de la contribución de la regla de reconocimiento a la identidad y a la legitimidad de los sistemas jurídicos. Planteo, después, la idea de que el rasgo distintivo de la función judicial desde un punto de vista institucional y normativo no es tanto el mantenimiento de la estabilidad del orden político cuanto la garantía de los derechos, subrayando las limitaciones de la tesis analizada en este artículo en contextos de transformación del orden jurídic…

Judicial functionmedia_common.quotation_subjectIdentity (social science)SafeguardingGarzón Valdés ErnestoErnesto Garzón ValdésPoliticsPolitical science:CIENCIAS JURÍDICAS Y DERECHO::Teoría y métodos generales::Filosofía del derecho [UNESCO]SustenanceJurisprudence. Philosophy and theory of lawEstabilidad políticaFunction (engineering)Legitimacymedia_commonFilosofía del DerechoPolitical stabilityUNESCO::CIENCIAS JURÍDICAS Y DERECHO::Teoría y métodos generales::Filosofía del derechoK201-487K1-7720PhilosophyLaw in general. Comparative and uniform law. JurisprudenceFunción judicialErnesto Garzón Valdés ; Función judicial ; Estabilidad política ; LegitimidadLawRule of recognitionNormativeLegitimidadLawLegitimacy
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Alcune riflessioni sull’indipendenza giudiziaria nel contesto europeo

2023

This article aims to provide some reflections on the links between judiciary independence, the rule of law, and the role of judges both national and European. First of all, it focuses on the evolution of the role of the judge in the constitutional and European systems. Then, it shows how the European Court of Justice and the European Court of Human Rights have developed criteria to ensure the independence of judges, analysing them. Moreover, it examines the criteria that have been developed by the European courts and by the opinions of the Consultative Council of European Judges about the independence of the Judiciary Councils.

Judiciary Independence European Court of Justice European Court of Human Rights Rule of law Judicial Council.Settore IUS/21 - Diritto Pubblico Comparato
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L'ordinamento giudiziario. Ciclo di seminari (Palermo, marzo-maggio, 2018)

2019

The collected contributions constitute the backbone of a series of seminars on the “Judiciary rules”, which took place in the spring of 2018 in the context of the master's degree course in Law of the University of Palermo. The volume aims to offer the trainee lawyer a closer look at a profile not always investigated of the jurisdictional activity: that of the constitution and functioning of the offices of the ordinary judiciary. Even in their unity, the issues addressed can ideally be divided into two thematic areas: the first aims to provide a general view of the system; the second is dedicated to the analysis of specialized sections and the honorary judiciary. In the appendix, the feature…

Judiciary ruleconstitution and functioning of the offices of the ordinary judiciarySettore IUS/08 - Diritto CostituzionaleJudicial Council
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Jurisprudencia valorativa y jurisprudencia creativa

2023

After analyzing pros and cons of the legal syllogism, the chapter contextualizes the opposition between evaluative and creative jurisprudence in the current evolution of law, finding in the respect of the rule of law the key for the correct reading of the judicial decision-making. The latter is a contribution to the building of the legal system in which it is possible a form of participation of the parties

JurisprudenceSettore IUS/20 - Filosofia Del DirittojudgeRule of lawinterpretationlegal thought.
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Human kininogens interact with M protein, a bacterial surface protein and virulence determinant.

1995

Streptococcus pyogenes, the most significant streptococcal species in clinical medicine, expresses surface proteins with affinity for several human plasma proteins. Here we report that kininogens, the precursors to the vasoactive kinins, bind to the surface of S. pyogenes. M protein, a surface molecule and a major virulence factor-in these bacteria, occurs in > 80 different serotypes. Among 49 strains of S. pyogenes, all of different M serotypes, 41 bound radiolabelled kininogens, whereas 6 M protein-negative mutant strains showed no affinity. M protein of most serotypes bind fibrinogen, and among the 55 strains tested, binding of kininogens was closely correlated to fibrinogen bindi…

Kininogen bindingMyeloma proteinStreptococcus pyogenesM1 proteinMolecular Sequence DataEnzyme-Linked Immunosorbent Assaymedicine.disease_causeBiochemistryPeptide MappingAntibodiesBacterial ProteinsmedicineHumansAmino Acid SequenceBinding siteMolecular BiologyKininogenAntigens BacterialBinding SitesbiologyVirulenceKininogensFibrinogen bindingFibrinogenCell BiologyLow-molecular-weight kininogenMolecular biologyStreptococcus pyogenesbiology.proteinCarrier Proteinscirculatory and respiratory physiologyResearch ArticleBacterial Outer Membrane ProteinsProtein Binding
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