Search results for "RUN"

showing 10 items of 2820 documents

Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment

2016

// Marta Jessica Llorca-Cardenosa 1, * , Tania Fleitas 1, * , Maider Ibarrola-Villava 1 , Maria Pena-Chilet 1 , Cristina Mongort 2 , Carolina Martinez-Ciarpaglini 2 , Lara Navarro 2 , Valentina Gambardella 1 , Josefa Castillo 1 , Susana Rosello 1 , Samuel Navarro 2 , Gloria Ribas 1 , Andres Cervantes 1 1 Medical Oncology, Biomedical Research Institute INCLIVA, University of Valencia, Valencia, Spain 2 Department of Pathology, Biomedical Research Institute INCLIVA, University of Valencia, Valencia, Spain * These authors contributed equally to this work Correspondence to: Gloria Ribas, email: gribas@incliva.es Andres Cervantes, email: andres.cervantes@uv.es Keywords: RUNX3, ARID1A, gastric ca…

Male0301 basic medicineRUNX3immune microenvironmentBiologyEpigenesis Genetic03 medical and health sciences0302 clinical medicineStomach NeoplasmsCDKN2ABiomarkers TumorTumor MicroenvironmentmedicineHumansEpigeneticsPromoter Regions GeneticAgedAged 80 and overTumor microenvironmentgastric cancerMicrosatellite instabilityCancerMethylationDNA MethylationMiddle AgedPrognosismedicine.diseaseARID1Adigestive system diseasesSurvival RateCore Binding Factor Alpha 3 Subunit030104 developmental biologyOncologyTumor progressionCase-Control Studies030220 oncology & carcinogenesisDNA methylationImmunologyCancer researchCpG IslandsFemaleMicrosatellite InstabilityFollow-Up StudiesResearch Papergene methylationOncotarget
researchProduct

Participation and performance trends in 100-km ultra-marathons worldwide

2014

The aims of the present study were to (1) investigate the participation trends for the origin of athletes competing in 100-km ultra-marathons and (2) determine the nationalities of athletes achieving the fastest 100-km race times worldwide. Race times and nationality from 112,283 athletes (15,204 women and 97,079 men) from 102 countries who completed a 100-km ultra-marathon worldwide between 1998 and 2011 were investigated using single- and multi-level regression analyses. The number of finishers increased exponentially, both for women and men. Most of the finishers (73.5%) were from Europe, in particular, France (30.4%). The number of finishers from Japan, Germany, Italy, Poland and the Un…

Male11035 Institute of General PracticeCanadaCompetitive BehaviorTime FactorsEthnic groupPhysical Therapy Sports Therapy and Rehabilitation610 Medicine & healthAthletic PerformanceRunningSex Factors2732 Orthopedics and Sports MedicineJapanSex factorsEthnicityHumansOrthopedics and Sports Medicine3612 Physical Therapy Sports Therapy and RehabilitationbiologyAthletesAge FactorsAfrica Easternbiology.organism_classificationUnited StatesEuropeGeographyAthletesCompetitive behaviorPhysical EnduranceNationalityFemaleDemography
researchProduct

European athletes dominate performances in Double Iron ultra-triathlons - A retrospective data analysis from 1985 to 2010

2014

International audience; We investigated the participation and performance trends of ultra-endurance triathletes from all nationalities competing in a Double Iron ultra-triathlon (7.6-km swim, 360-km cycle and 84.4-km run) from 1985 to 2010. A total of 1854 athletes participated in 92 Double Iron ultra-triathlons. The majority of the winners came from Europe with 72 victories, followed by North America with 17 victories. The race time for the European ultra-triathletes was 1340 (s=95.3) min, decreasing highly significantly (r(2)=0.28; P<0.0001) across the years. North American ultra-triathletes finished the races within 1556 (s=124.5) min; their race time showed no changes across the years (…

Male11035 Institute of General PracticeFuture studiesPhysical Therapy Sports Therapy and Rehabilitation610 Medicine & healthCHILDRENEXERCISEAthletic PerformanceRetrospective data2732 Orthopedics and Sports MedicineAGEADOLESCENTSHumansOrthopedics and Sports Medicine3612 Physical Therapy Sports Therapy and RehabilitationPREDICTORSUltra enduranceAnalysis of VariancebiologyENDURANCE RUNNERSAthletesLife styleRACE TIMEGeneral Medicinebiology.organism_classificationEuropeGeographyCYCLING PERFORMANCEDEMOGRAPHIC CHARACTERISTICSAthletesNorth AmericaLinear ModelsFemaleLIFE-STYLE[ SCCO ] Cognitive scienceSportsDemography
researchProduct

''Limits in endurance performance of octogenarian athletes''

2013

TO THE EDITOR: A recent study of Trappe et al. (3) showed that the aerobic power of octogenarian lifelong endurance athletes was approximately double that of untrained octogenarians (38 vs. 21 ml·kg 1 ·min 1 ). These remarkable aerobic capacities are the highest ever recorded in this age group. However, the impact of the identified physiological capacities on actual endurance performances has not been addressed, as no running performance indicators of the octogenarian athletes were provided in this study. We hereby suggest that, although trained octogenarian athletes can achieve levels of aerobic fitness well above their untrained counterpart, as a group they actually have not yet reached t…

Male11035 Institute of General PracticeGerontologymedicine.medical_specialtyPhysiology[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]Marathon running610 Medicine & health03 medical and health sciences2737 Physiology (medical)0302 clinical medicinePhysiology (medical)medicine[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]HumansAerobic exerciseExercise physiologyLetters to the EditorExerciseComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbiologybusiness.industryAthletes[ SDV.MHEP.PHY ] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO][SCCO.NEUR]Cognitive science/Neuroscience1314 Physiology030229 sport sciencesbiology.organism_classificationAthletes[ SCCO.NEUR ] Cognitive science/NeurosciencePhysical EndurancePhysical therapyMasters athletesbusiness
researchProduct

''Sex Differences In Ultra-triathlon Performance At Increasing Race Distance''

2013

Ruest, Christoph Alexander | Knechtle, Beat | Knechtle, Patrizia | Rosemann, Thomas | Lepers, Romuald; International audience; ''It has been argued that women should be able to outrun men in ultra-endurance distances. The present study investigated the sex difference in overall race times and split times between elite female and male Ironman triathletes competing in Ironman Hawaii (3.8 km swimming, 180 km cycling, and 42.195 km running) and Double Iron ultra-triathletes (7.6 km swimming, 360 km cycling, and 84.4 km running). Data from 20,638 athletes, including 5,163 women and 15,475 men competing in Ironman Hawaii and from 143 women and 1,252 men competing in Double Iron ultra-triathlon ra…

Male11035 Institute of General PracticeTOTAL-BODY WATERExperimental and Cognitive Psychology610 Medicine & healthSWIMMERSEXERCISE030204 cardiovascular system & hematologyAthletic PerformanceMuscle massRunningSWIMMERS''03 medical and health sciencesRace (biology)2809 Sensory Systems0302 clinical medicineSex FactorsPEAK PERFORMANCEHumansMUSCLE MASSSwimmingGENDER-DIFFERENCESbiologyAthletes3205 Experimental and Cognitive Psychology''TOTAL-BODY WATER[SCCO.NEUR]Cognitive science/NeuroscienceVO2 maxWOMEN030229 sport sciencesAnthropometrybiology.organism_classificationSkeletal muscle massSensory SystemsBicycling[ SCCO.NEUR ] Cognitive science/NeuroscienceRUNNERSPhysical EnduranceFemaleOUTRUN MENRUNNING PERFORMANCECyclingDemography
researchProduct

Acute Effects of Loaded Half-Squat Jumps on Sprint Running Speed in Track and Field Athletes and Soccer Players

2016

The purpose of the study was to determine the acute responses to a jump squat protocol designed to induce postactivation potentiation on sprint running performance in experienced track and field athletes and soccer players. Twenty-five regional level athletes (12 track and field: ∼17 years; ∼177 cm; ∼73 kg and 13 soccer: ∼18 years; ∼175 cm; ∼72 kg) performed 2 test sessions assessing 40-m sprint running performance in a balanced, crossover design. Dual-beam light timing gates measured 0-20 and 20-40 m sprint times before and after either 9 minutes of sitting (control) or 2 sets of 6 repetition half-squat jump with the load eliciting maximum power (experimental) conditions. Sprint performanc…

MaleAcute effectsmedicine.medical_specialtyAdolescentPhysical Therapy Sports Therapy and RehabilitationSquatcomplex trainingAthletic Performance030204 cardiovascular system & hematologySittingRunningpower03 medical and health sciences0302 clinical medicineSoccermedicineHumansOrthopedics and Sports MedicineMuscle StrengthTrack and field athleticsta315MathematicsbiologyAthletesTrack and Field030229 sport sciencesGeneral Medicinebiology.organism_classificationperformance enhancementPAPSprintAthletesPhysical therapyPost activation potentiationJumpcontrast trainingJournal of Strength and Conditioning Research
researchProduct

Physical Fitness and Hormonal Profile During an 11-Week Paratroop Training Period.

2015

Physical fitness and serum hormone concentrations have been shown to change during military training. The purpose was to examine these chronic changes in paratroopers (n = 52 male conscripts) during an 11-week training period, including acute changes induced by strenuous 5-day military field training. Hormonal profiles, body mass, maximal strength, muscle endurance, and 12-minute running test were assessed at several time points during paratrooper training. In the latter part of the training period, conscripts were involved in strenuous military field training (5 days). At week 7, during specialized military training period, aerobic performance decreased (3,146 ± 163 m) but recovered back t…

MaleAdolescentHydrocortisonemedicine.drug_classconscriptPhysical fitnessPhysical Therapy Sports Therapy and RehabilitationRunningYoung AdultAnimal scienceSex hormone-binding globulinSex Hormone-Binding GlobulinmedicineHumansOrthopedics and Sports MedicineTestosteroneMuscle Strengthta315Muscle SkeletalTestosteronemilitaryFinlandHydrocortisoneTraining periodExercise Tolerancebiologyhormonesbusiness.industryBody WeightVO2 maxGeneral MedicineAndrogenMilitary PersonnelLower ExtremityPhysical Fitnessbiology.proteinBody CompositionPhysical Endurancebusinessmedicine.drugHormonePhysical Conditioning HumanJournal of strength and conditioning research
researchProduct

Developmental associations of accelerometer measured moderate-to-vigorous physical activity and sedentary time with cardiorespiratory fitness in scho…

2022

Objectives This study examined the developmental associations of accelerometer-based moderate-to-vigorous physical activity (MVPA) and sedentary time (ST) with cardiorespiratory fitness (CRF) in schoolchildren. Design A three-year follow-up study. Methods Participants were 446 (girls 57 %) Finnish children (M = 11.26 ± 0.32 years) from 17 randomly selected public schools in Finland. Accelerometer-based MVPA and ST were assessed using waist-worn activity monitors and CRF using the 20 m shuttle run test at four measurement points from 2017 to 2020. The developmental associations were tested using the Random Intercept Cross-Lagged Panel Model (RI-CLPM) reflecting MVPA, CRF, and ST overall leve…

MaleAdolescentexercisekoululaisetPhysical Therapy Sports Therapy and Rehabilitationhealth20 m shuttle runliikuntastructural equation modelingfyysinen kuntoCardiorespiratory FitnessPhysical FitnessAccelerometryphysical fitnessHumansFemaleOrthopedics and Sports MedicineSedentary BehaviorChildrakenneyhtälömallintaminenExerciseterveysFollow-Up Studies
researchProduct

Does tinnitus distress depend on age of onset?

2011

Objectives: Tinnitus is the perception of a sound in the absence of any physical source of it. About 5–15% of the population report hearing such a tinnitus and about 1–2% suffer from their tinnitus leading to anxiety, sleep disorders or depression. It is currently not completely understood why some people feel distressed by their tinnitus, while others don’t. Several studiesindicate that the amount of tinnitus distress is associated with many factors including comorbid anxiety, comorbid depression, personality, the psychosocial situation, the amount of the related hearing loss and the loudness of the tinnitus.Furthermore, theoretical considerations suggest an impact of the age at tinnitus o…

MaleAgingAnatomy and PhysiologyDatabases Factuallcsh:Medicine10045 Clinic for OtorhinolaryngologyAudiologySocial and Behavioral SciencesTinnitusddc:150GermanySurveys and QuestionnairesPsychologyAge of Onsetlcsh:ScienceDepression (differential diagnoses)PsychiatryAged 80 and overeducation.field_of_studyMultidisciplinaryDDC 150 / PsychologyTinnitus auriumAge FactorsAudiologyMiddle AgedSensory SystemsDistressMental HealthAuditory SystemAnxietyMedicineSensory PerceptionFemaleAltermedicine.symptomPsychosocialResearch ArticleAdultmedicine.medical_specialtyAdolescentHearing lossPopulationPsychological Stress610 Medicine & health1100 General Agricultural and Biological SciencesOhrgeräuschYoung Adult1300 General Biochemistry Genetics and Molecular Biologymedicineotorhinolaryngologic diseasesHumanseducationBiologyAgedComputational Neuroscience1000 MultidisciplinaryEvolutionary BiologyPopulation Biologybusiness.industryMood Disorderslcsh:RComputational BiologyHearing lossLogistic ModelsOtorhinolaryngologylcsh:QAge of onsetbusinessPhysiological ProcessesHörstörungOrganism DevelopmentTinnitusDevelopmental BiologyNeuroscience
researchProduct

Musculoskeletal fitness and balance in older individuals (65–85 years) and its association with steps per day: a cross sectional study

2015

Background There is limited normative, objective data combining musculoskeletal fitness (MSF), balance and physical activity (PA) among older adults. The aims were therefore to; 1) describe MSF and balance in older Norwegian adults focusing on age- and sex-related differences; 2) investigate the associations among MSF, balance and objectively-assessed PA levels. Methods This was part of a national multicenter study. Participants (65–85 years) were randomly selected from the national population registry. We used ActiGraph GT1M accelerometers to measure PA. Balance and MSF were assessed using: one leg standing (OLS), handgrip strength (HG), static back extension (SBE), sit and reach (SR), bac…

MaleAgingFitness scoremedicine.medical_specialtyCross-sectional studyPopulationPhysical fitnessRandom Allocation03 medical and health sciences0302 clinical medicineHand strengthAccelerometryPostural BalancemedicineHumans030212 general & internal medicineeducationGeriatric AssessmentPostural BalanceAgedBalance (ability)Aged 80 and overeducation.field_of_studyUnivariate analysisMuscle WeaknessHand StrengthNorwaybusiness.industryAge Factors030229 sport sciencesTrunkCross-Sectional StudiesPhysical FitnessPhysical EndurancePhysical therapyFemaleAccelerometer-determined physical activityOlder peopleGeriatrics and GerontologybusinessResearch ArticleBMC Geriatrics
researchProduct