Search results for "R_GAMMA"
showing 2 items of 2 documents
"Table 7" of "Measurement of dielectron production in central Pb-Pb collisions at $\sqrt{{\textit{s}}_{\mathrm{NN}}}$ = 2.76 TeV"
2018
Direct photon ratio $R_{\gamma^{(*)}}=1+\gamma^{(*)}_{\mathrm{dir}}/\gamma^{(*)}_{\mathrm{decay}}$ measured using virtual photons in the centrality range 0$-$10$\%$. The statistical and systematic uncertainties of the data are represented by vertical bars and boxes.
A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability
2017
AbstractProteomics based approaches are emerging as useful tools to identify the targets of bioactive compounds and elucidate their molecular mechanisms of action. Here, we applied a chemical proteomic strategy to identify the peroxisome proliferator-activated receptor γ (PPARγ) as a molecular target of the pro-apoptotic agent 15-ketoatractyligenin methyl ester (compound 1). We demonstrated that compound 1 interacts with PPARγ, forms a covalent bond with the thiol group of C285 and occupies the sub-pocket between helix H3 and the β-sheet of the ligand-binding domain (LBD) of the receptor by Surface Plasmon Resonance (SPR), mass spectrometry-based studies and docking experiments. 1 displayed…