Search results for "Raf"
showing 10 items of 11050 documents
Preclinical models in oncological pharmacology: limits and advantages
2021
A wide range of experimental tumor models, each with distinct advantages and disadvantages, is nowadays available. Due to the inherent differences in their complexity and functionality, the choice of the model is usually dependent on the application. Thus, to advance specific knowledge, one has to choose and use appropriate models, which complexity is largely dependent on the hypotheses to test, that is on the objectives. Whatever the model chosen, the complexity of cancer is such that none of them will be able to fully represent it. In vitro tumor models have provided important tools for cancer research and still serve as low-cost screening platforms for drugs. The improved understanding o…
3D numerical modeling of an anthropogenic sinkhole in the Marsala area of western Sicily
2013
Sistemi informativi 3D per i BB.CC. e l'archeologia: il Castello di Maredolce a Palermo
2014
Il mondo della ricerca nel campo dei BB.CC. sta guardando con sempre maggior interesse all’uso di tecnologie informatiche integrate, che consentano di fornire e condividere in rete dati quantitativi e qualitativi, geometrici, posizionali, alfanumerici, relativi ai BB.CC., sfruttando l’interazione tra banche dati e modelli 3D. Tali modelli, dunque, oltre a fornire una ricostruzione virtuale del monumento con la possibilità di navigare ed analizzare l’oggetto in dettaglio, costituiscono lo strumento per accedere ad informazioni eterogenee (testi, immagini, sequenze video, ecc.) sui manufatti, raccolte ed organizzate in database relazionali interrogabili, al fine di una piena comprensione e co…
Towards Digital Twinning on the Web: Heterogeneous 3D Data Fusion Based on Open-Source Structure
2023
Recent advances in Computer Science and the spread of internet connection have allowed specialists to virtualize complex environments on the web and offer further information with realistic exploration experiences. At the same time, the fruition of complex geospatial datasets (point clouds, Building Information Modelling (BIM) models, 2D and 3D models) on the web is still a challenge, because usually it involves the usage of different proprietary software solutions, and the input data need further simplification for computational effort reduction. Moreover, integrating geospatial datasets acquired in different ways with various sensors remains a challenge. An interesting question, in that r…
Smiltsērkšķu marafivīrusa kodēto proteīnu klonēšana, ekspresija un raksturošana
2022
Smiltsērķšu marafivīruss (SBuMV) ir iepriekš neraksturots, smiltsērkšķus inficējošs vīruss. Tam ir divas atklātās translācijas fāzes (ORF), kur ORF1 kodē poliproteīnu, kas satur četrus proteīnu domēnus, bet ORF2 kodē apvalka proteīnu (CP). Šajā darbā tika izveidotas ekspresijas plazmīdas SBuMV kodētajiem proteīniem, taču E. coli sistēmā izdevās ekspresēt un attīrīt tikai abas CP formas un proteāzes (PRO) domēnu. Tika pārbaudīta PRO aktivitāte, PRO šķelšanas saits un verificēta PRO deubikvitināzes (DUB) aktivitāte. SBuMV mažorais CP E. coli spēj pašsavākties vīrusam līdzīgajās daļinās (VLP), bet minorais CP veido agregātus. Koekspresijas rezultātā, ja abas CP formas ekspresē no vienas plazmī…
MOBILE MAPPING FOR CULTURAL HERITAGE: THE SURVEY OF THE COMPLEX OF ST. JOHN OF THE HERMITS IN PALERMO (ITALY)
2023
Abstract. During the 11th and 12th century, the Arab-Norman architectural style characterized the most beautiful and important Cultural Heritage buildings in Sicily, and especially in Palermo (Italy). The relevance of these monuments is highlighted by their inclusion in the UNESCO World Heritage Sites List in 2015. For many years, the University of Palermo has been studying and documenting several Arab-Norman cultural assets, and in particular, the complex of St. John of the Hermits in Palermo (Italy). A first detailed 3D survey of the main structures of this complex was carried out using a terrestrial laser scanner while the 3D survey of the entire complex was made using a Mobile Mapping S…
GEOMATIC TECHNIQUES FOR THE COLONNADE STRUCTURAL ANALYSIS OF THE HISTORICAL “ CHIARAMONTE STERI” BUILDING
2019
The monitoring of building structures has an increasingly important role in the engineering field, above all because they are concerned with the impact that such structures have in the area where they were built. Often, when walking through the old town centres, we realize just how obsolete and dangerous some buildings (even historic-cultural ones) are. The interest of some local governments in this problem has led, in the last few years, to the study and the trying out of measuring and monitoring methods which, quickly and at low cost, allow to define the extent of the deformation and the degrade in an accurate and reliable way. The Courtyard of “Palazzo Steri - Chiaramonte” is composed of…
TECNOLOGIE DI RILIEVO 3D PER LA DOCUMENTAZIONE, L’INTERPRETAZIONE E LA VALORIZZAZIONE DEL PATRIMONIO ARCHEOLOGICO: IL CASO STUDIO DEL PARCO ARCHEOLOG…
2020
In recent decades, the application of geomatics technologies and methodologies to archaeological studies has led to a substantial change in onsite survey techniques and allowed an interdisciplinary approach between archaeology and digital technologies. The employment of these techniques aims to reduce the time of research and documentation, to acquire large amounts of data and to manage, in a more efficiently and quickly way, different datasets. Moreover, these new approaches provide non-invasive, flexible, low-cost methodologies to improve archaeological documentation from a quantitative and qualitative point of view. Nowadays, archaeologists can take advantage of various recording techniq…
Impiego di 3D Web-service e software open-source nel rilievo di reperti archeologici: valutazioni metriche
2013
The Structure From Motion (SFM) algorithms derived from Computer Vision community make image-based techniquesa competitive and user friendly approach to obtain 3D information of real objects. These algorithms have been implemented in many 3D web-service and open source softwareto develop free instruments for the reconstruction of very detailed 3D digital models. Their useare becoming very common above all in archaeological studies but their potentiality for metric application have not been tested at all.The aim of the work is to investigate the quality and the accuracy of 3D models obtained through 3D web-service and SFM open source software.Different tests have been performed using some 3D…
Näkymänhallintatekniikat 3D-grafiikkamoottoreissa
2011
Tässä tutkielmassa käsittelen näkymänhallintatekniikoita 3D-grafiikkamoottoreissa. Näkymä muodostetaan monikulmiomalleista. Näkymänhallinta kuvaa algoritmit ja menetelmät, joiden tarkoituksena on valita kyseisen maailman kaikista monikulmioista ne, jotka pitää piirtää katsojan lokaation ja orientaation perusteella. Renderöitäessä satojatuhansia polygoneja käyttäen lukuisia efektejä käytettävä näkymänhallintatekniikka on tärkeässä asemassa. Tutkielmassa on tarkoitus esittää eri näkymänhallintatekniikoiden toteutuksia, osoittaa millaisille näkymille mikäkin menetelmä on paras ja verrata menetelmien suorituskykyä.