Search results for "Raffinose"

showing 2 items of 22 documents

Pancreatic islets from non-heart beating donor pig: Two-layer preservation method in an in vitro porcine model

2011

Purpose Pancreata from non-heart beating donors could represent an unlimited source of islets if their cell viability can be efficiently preserved during the time necessary to process the organs by the use of a better solution of preservation compared to the classic University of Wisconsin solution. The aim of this study was to determine whether it is possible to obtain functioning “alive islets” from non-heart-beating donors by comparing, on a porcine model, the classic “UW ice-store” method with a two-layer cold storage method (TLM) using oxygenated Perfluorocarbons (PFC) and UW. Methods Whole pancreata were harvested from 20 NHBDs female pigs with similar characteristics and preserved fo…

medicine.medical_specialtyAdenosineTime FactorsCell SurvivalSwineTwo-layer method UW solution non-heart beating donor pig pancreas preservationAllopurinolOrgan Preservation SolutionsBiomedical EngineeringIslets of Langerhans TransplantationMedicine (miscellaneous)Cold storageBioengineeringBiologyCold Ischemia TimeCryopreservationBiomaterialsTissue Culture TechniquesIslets of LangerhansRaffinoseSettore BIO/13 - Biologia ApplicataInternal medicinemedicineAnimalsInsulinViaspanViability assayCryopreservationgeographyFluorocarbonsgeography.geographical_feature_categoryPancreatic isletsCold IschemiaGeneral MedicineIsletGlutathioneIn vitroOxygenSettore MED/18 - Chirurgia GeneraleEndocrinologymedicine.anatomical_structureFemaleTissue Preservation
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Ischemic type biliary lesions in histidine-tryptophan-ketoglutarate (HTK) preserved liver grafts.

2006

Ischemic type biliary lesions lead to considerable morbidity following orthotopic liver transplantation. The exact pathogenesis is unknown. One major hypothesis is that insufficient perfusion of the arterial vessels of the biliary tree, especially under perfusion with the high viscous University of Wisconsin solution, might be responsible for ischemic type biliary lesions. Due to low viscosity, HTK solution is reported to have a lower incidence of biliary complications. However, there is no data concerning ischemic type biliary lesions in HTK preserved livers. In this paper we report our results after orthotopic liver transplantation with special regard to ischemic type biliary lesions in …

medicine.medical_specialtyAdenosinemedicine.medical_treatmentAllopurinolOrgan Preservation Solutions030232 urology & nephrologyBiomedical EngineeringMedicine (miscellaneous)Bioengineering030204 cardiovascular system & hematologyLiver transplantationHTK solutionGastroenterologyPotassium ChlorideBiomaterialsPathogenesisHistidine-tryptophan-ketoglutarate03 medical and health sciences0302 clinical medicineRaffinoseIschemiaInternal medicinemedicineHumansInsulinViaspanMannitolProspective Studiesbusiness.industryImmunosuppressionGeneral MedicineOrgan PreservationMiddle AgedGlutathioneLiver TransplantationTransplantationGlucoseBile DuctsbusinessPerfusionProcaineThe International journal of artificial organs
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