Search results for "Rain"

Mechanizm neuroplastyczności i jego znaczenie dla psychoterapii oraz oceny jej skuteczności

2016

The paper introduces the mechanism of neuroplasticity, specifically the ability of the brain to develop new neurons (neurogenesis) and new connections between nerve cells (synaptogenesis) and to develop glial cells. The author presents the evidence proving the existence of neuroplasticity by giving examples of people with serious brain damage who function normally and, above all, of people living with almost no brain or with one hemisphere, or with post-stroke defects. However, the main purpose of this paper is to present the current state of knowledge of the importance of the brain plasticity for the course of psychotherapy, as well as for assessing its effectiveness. The author gives many…

Työyhteisössä toteutetun kevyen liikuntaharjoittelun vaikutus työntekijöiden kokemaan psyykkiseen hyvinvointiin ja elämän laatuun

2001

Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics

2012

In this paper we propose a firing statistics based neuronal network burst detection algorithm for neuronal networks exhibiting highly variable action potential dynamics. Electrical activity of neuronal networks is generally analyzed by the occurrences of spikes and bursts both in time and space. Commonly accepted analysis tools employ burst detection algorithms based on predefined criteria. However, maturing neuronal networks, such as those originating from human embryonic stem cells (hESCs), exhibit highly variable network structure and time-varying dynamics. To explore the developing burst/spike activities of such networks, we propose a burst detection algorithm which utilizes the firing …

Pankin pääomarakenne ja varainhankinta nykyisessä ja tulevassa pankkisääntelyssä

2017

Tämä tutkielma kokoaa yhteen pankkeja nykyisin velvoittavat pääomien määrään ja maksuvalmiuteen sekä rahoitukseen liittyvät sääntelyt. Tutkielman tavoitteena on saada vastaus kysymykseen: Miten pankin tulee huomioida pankkisääntely pääoman ja varainhankinnan rakenteessaan? Tutkielman alussa esitellään pankkitoimintaa yleisesti ja siihen liittyviä optimointiongelmia. Pankkien kannalta optimaalinen pääomarakenne poikkeaa sosiaalisesti optimaalisesta ja tätä varten pankkisääntelyä tarvitaan. Optimaalisimman tason määrittely on haastavaa, mutta sen on arvioitu olevan 15-20 % tasolla. Pääomarakenteella on vaikutusta pankin tuottavuuteen ja menestymisen mahdollisuuksiin. Pankkeja voidaan säännell…

The state-of-the-art of collaborative technologies for initial vocational education : a systematic literature review

2018


 
 
 Future workplaces require collaboration skills in which members of different work communities use technologies to solve complex problems. Vocational education and training (VET) programs need to meet the challenge to prepare students to be part of a competent workforce. Particularly initial vocational education is under pressure to develop learners’ collaboration skills and abilities. To date, however, no attempt has been made to perform a comprehensive review of the use of computer-supported collaborative learning (CSCL) technologies across different vocational education settings to account for contextual factors of VET. In this systematic review, 26 published studies …

Spatial variation in the evolutionary potential and constraints of basal metabolic rate and body mass in a wild bird

2023

An organism's energy budget is strongly related to resource consumption, performance, and fitness. Hence, understanding the evolution of key energetic traits, such as basal metabolic rate (BMR), in natural populations is central for understanding life-history evolution and ecological processes. Here we used quantitative genetic analyses to study evolutionary potential of BMR in two insular populations of the house sparrow (Passer domesticus). We obtained measurements of BMR and body mass (Mb) from 911 house sparrows on the islands of Leka and Vega along the coast of Norway. These two populations were the source populations for translocations to create an additional third, admixed ‘common ga…

Water Dynamics in Biological Systems investigated using Neutron Scattering Techniques

Living systems can not survive in absence of the water environments which play a fundamental role in living functions. Thus in the scienti?c community many studies were and are addressed to characterize water and its dynamics properties in biological systems. However, a clear description of water in such systems has been not reached yet. In fact, the investigations performed with di?erent techniques - those based on Nuclear Magnetic Resonance or those based on Neutron Scattering - look at di?erent di?usive motions and interactions water-biomolecules, leading controversial results and hence generating many debates between scientists. In this thesis we support the idea that two water populati…

Problem solving e metacognizione. L’uso didattico del prompt per sviluppare strategie di problem solving nei futuri maestri

2015

Si presentano i risultati di una ricerca che ha coinvolto in totale 235 studenti del corso di Laurea in Scienze della Formazione Primaria dell’Università di Palermo. Con la ricerca si è inteso individuare le metodologie di sostegno atte a promuovere nei futuri maestri da una parte la capacità di identificare e affrontare situazioni scolastiche problematiche in modo adeguato; dall’altra la capacità di riflettere metacognitivamente sul processo di risoluzione del problema. La ricerca costituisce un esempio di come si possa sviluppare nei futuri insegnanti in formazione quell’insieme di abilità cognitive e metacognitive che confluiscono nella capacità di identificare e risolvere situazioni edu…

Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis.

2005

Objective— Sedentary lifestyle is associated with increased cardiovascular events. The underlying molecular mechanisms are incompletely understood. Reactive oxygen species (ROS) contribute to endothelial dysfunction and atherosclerosis. An important source of vascular ROS is the NADPH oxidase. Methods and Results— C57BL6 mice were subjected to regular housing (physical inactivity) or voluntary training on running wheels (6 weeks). Inactivity increased vascular lipid peroxidation to 148±9% and upregulated superoxide release to 176±17% (L-012 chemiluminescence) and 188±29% (cytochrome C reduction assay), respectively. ROS production was predominantly increased in the endothelium and the medi…

Molecular Mechanisms of the Blockage of Glioblastoma Motility

2021

Glioblastoma (GBM) is the most common and lethal brain tumor. GBM has a remarkable degree of motility and is able to infiltrate the healthy brain. In order to perform a rationale-based drug-repositioning study, we have used known inhibitors of two small Rho GTPases, Rac1 and Cdc42, which are upregulated in GBM and are involved in the signaling processes underlying the orchestration of the cytoskeleton and cellular motility. The selected inhibitors (R-ketorolac and ML141 for Cdc42 and R-ketorolac and EHT 1864 for Rac1) have been successfully employed to reduce the infiltration propensity of GBM in live cell imaging studies. Complementarily, all-atom simulations have elucidated the molecular …