Search results for "Randomised"

showing 4 items of 44 documents

A Group Intervention to Promote Resilience in Nursing Professionals: A Randomised Controlled Trial

2022

In this study, a new group intervention program to foster resilience in nursing professionals was tested for efficacy. In total, 72 nurses were recruited and randomised to either an intervention condition or to a wait list control condition. The study had a pre-test, post-test, follow-up design. The eight-week program targeted six resilience factors: cognitive flexibility, coping, self-efficacy, self-esteem, self-care, and mindfulness. Compared to the control group, the intervention group reported a significant improvement in the primary outcome mental health (measured with the General Health Questionnaire) from pre-test (M = 20.79; SD = 9.85) to post-test (M = 15.81; SD = 7.13) with an est…

mental health; resilience; nursing; occupational stress; psychotherapy; coping; randomised controlled trialHealth Toxicology and MutagenesisRPublic Health Environmental and Occupational HealthResilience Psychologicalresilience ; mental health ; nursing ; occupational stress ; coping ; randomised controlled trial ; psychotherapySelf EfficacyArticlepsychotherapycopingMental HealthnursingMedicineHumansMindfulnessresiliencerandomised controlled trialoccupational stressRetrospective StudiesInternational Journal of Environmental Research and Public Health
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Real-world experience with obeticholic acid in patients with primary biliary cholangitis

2021

Background & aims Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety of OCA under real-world conditions. Methods Patients were recruited into the Italian PBC Registry, a multicentre, observational cohort study that monitors patients with PBC at national level. The primary endpoint was the biochemical response according to Poise criteria; the secondary endpoint was the biochemical response according to normal range criteria, defined as normal levels of bilirubin, alkaline phosphatase (ALP), and alanine aminotransfer…

upper limit of normalCirrhosisALTAMAAutoimmunityantinuclear antibodiesULNPBCGastroenterologyUDCASettore MED/12ULN upper limit of normalobeticholic acidaRR adjusted risk ratio.CRFs case record formAST aspartate transferaseClinical endpointGGT gamma-glutamyl transferaseQCprimary biliary cholangitisGastroenterologyUrsodeoxycholic acidANATCCCirrhosisCholestasiTIPSTreatment Completer CohortANA antinuclear antibodiemedicine.medical_specialtyRRUDCA ursodeoxycholic acidTIPS transjugular intrahepatic portosystemic shuntOCACirrhosiALP alkaline phosphataseautoimmune hepatitismedicine.diseasedigestive system diseasesDiscontinuationKeywords: AIH autoimmune hepatitiQC quality controlchemistrygamma-glutamyl transferaserandomised controlled trialelectronic data captureantimitochondrial antibodiesaspartate transferaseAutoimmune hepatitischemistry.chemical_compoundAIHCRFsImmunology and Allergyadjusted risk ratioANA antinuclear antibodiesRR risk ratioOverall cohortALT alanine transferaseAMA antimitochondrial antibodieCholestasisCRFs case record formsObeticholic acidOverlap PBC-AIHursodeoxycholic acidOCA obeticholic acidTolerabilityalkaline phosphataseRCTResearch Articlemedicine.drugcase record formsContext (language use)AMA antimitochondrial antibodiesInternal medicineEDC electronic data capturetransjugular intrahepatic portosystemic shuntInternal MedicinemedicineRCT randomised controlled trialaRR adjusted risk ratioOClcsh:RC799-869quality controlalanine transferaseASTaRRHepatologybusiness.industryAutoimmunity; Cholestasis; Cirrhosis; Overlap PBC-AIHAIH autoimmune hepatitisTCC Treatment Completer CohortPBC primary biliary cholangitiGGTrisk ratioOC Overall cohortALPlcsh:Diseases of the digestive system. GastroenterologyPBC primary biliary cholangitisbusinessEDC
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Effectiveness of a kindergarten-based intervention to increase vegetable intake and reduce food neophobia amongst 1-year-old children: a cluster rand…

2021

Background: Children’s first years of life are crucial to their future health. Studies show that a varied diet with a high intake of vegetables is positive in several domains of health. The present low vegetable intake amongst children is, therefore, a concern. Food neophobia is a common barrier to vegetable intake in children. As most Norwegian children attend kindergarten from an early age, kindergartens could contribute to the prevention of food neophobia and the promotion of vegetable intake. Objective: The aim of this study was to assess the effect of a cluster randomised trial amongst 1-year-old children in kindergarten to reduce food neophobia and promote healthy eating. Methods: Kin…

vegetablesHealthy eatingIntervention groupNorwegianDisease clustersensory educationVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 811childrenEnvironmental healthIntervention (counseling)medicineweb-based online resourceskindergartenTX341-641Cluster randomised controlled trialsapereMealNutrition and DieteticsNutrition. Foods and food supplybusiness.industryNeophobiaPublic Health Environmental and Occupational Healthfood neophobiamedicine.diseaselanguage.human_languagelanguageOriginal ArticlebusinessFood ScienceFood & Nutrition Research
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Effects of progressive aquatic resistance training on symptoms and quality of life in women with knee osteoarthritis: A secondary analysis.

2020

Abstract Objective: To conduct a secondary analysis to study the effects, those 4 months of aquatic resistance training have on self‐assessed symptoms and quality of life in post‐menopausal women with mild knee osteoarthritis (OA), after the intervention and after a 12‐month follow‐up period. Methods: A total of 87 post‐menopausal volunteer women, aged 60‐68 years, with mild knee OA were recruited in a randomized, controlled, 4‐month aquatic training trial (RCT) and randomly assigned to an intervention (n = 43) and a control (n = 44) group. The intervention group participated in 48 supervised aquatic resistance training sessions over 4 months while the control group maintained their usual l…

vesiliikuntaOsteoarthritis030204 cardiovascular system & hematologyGUIDELINESlaw.invention0302 clinical medicineSwimming PoolsRandomized controlled trialQuality of lifelawSecondary analysisSurveys and QuestionnairesMedicineOrthopedics and Sports Medicine315 Sport and fitness sciences4-MONTHVolunteerPain MeasurementOUTCOMESaquatic resistance trainingfollow‐up studyfollow-up studyRANDOMIZED CONTROLLED-TRIALMiddle AgedOsteoarthritis KneePostmenopauseWOMACFemaleseurantatutkimusLANDnivelrikkomedicine.medical_specialtyWOMACEXERCISEPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciencesCARTILAGEIntervention (counseling)HumansAgedbusiness.industryResistance trainingResistance Training030229 sport sciencesEFFICACYmedicine.diseaseosteoarthritisrandomized controlled trialPhysical therapyQuality of Lifebusinessrandomised controlled trialScandinavian journal of medicinescience in sportsREFERENCES
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