Search results for "Raphe"
showing 10 items of 839 documents
Perfluorocarbons–graphene oxide nanoplatforms as biocompatible oxygen reservoirs
2018
Abstract 3-Pentadecafluoroheptyl,5-perfluorophenyl-1,2,4-oxadiazole (FOX) molecules were attached onto a graphene oxide (GO) via a facile aromatic substitution in alkaline environment. This approach allows achieving high degree of functionalization under mild conditions. The covalent attachment of perfluoromoieties onto GO lamellae was confirmed by spectroscopic analyses. The performance of these nanoplatforms (GOF) as oxygen reservoirs was assessed at different concentrations and temperature. The results revealed that under physiologic conditions GO and FOX synergistically operate for increasing oxygen uptake and release, either from a thermodynamic and a kinetic point of view. Even at low…
Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice.
2007
The endocannabinoid system (ECS) possesses neuromodulatory functions by influencing the release of various neurotransmitters, including GABA, noradrenaline, dopamine, glutamate and acetylcholine. Even though there are studies indicating similar interactions between the ECS and the serotonergic system, there are no results showing clear evidence for type 1 cannabinoid receptor (CB1) location on serotonergic neurons. In this study, we show by in situ hybridization that a low but significant fraction of serotonergic neurons in the raphe nuclei of mice contains CB1 mRNA as illustrated by the coexpression with the serotonergic marker gene tryptophane hydroxylase 2, the rate limiting enzyme for t…
Bridging landscape graphs and genetic graphs for analysing habitat ecological connectivity
2021
Several key ecological processes for maintaining biodiversity rely upon the ecological connectivity of habitat. Accordingly, connectivity modelling methods have been developed for understanding precisely the influence of connectivity and deriving sound biodiversity conservation measures. Among them, landscape graphs represent habitat networks as sets of habitat patches (nodes) connected by potential dispersal paths (links). Yet, the ecological relevance of these tools required validation from biological data reflecting closely the influence of habitat connectivity. Genetic data allow for such validation as population genetic structure partly depends on dispersal-driven gene flow between hab…
Understanding the role of graphene oxide in the capture and eradication of circulating tumor cells
2016
The capture of circulating cancer cells on functional biomaterials is expected to control metastatic spread of a tumor, which is related to good probability containing the progression of disease burden. (1) The physicochemical characteristics of a biomaterial surface highly affect cell recruitment and adhesion, which is of great importance in such applications. Here, we designed a poly(caprolactone)-based nanocompsite scaffold, henceforth PCLMF-GO, to simultaneously recruit and kill circulating cancer cells by tuning physicochemical features of the scaffold surface through nitrogen plasma activation and hetero-phase graphene oxide (GO) covalent functionalization. Nitrogen plasma activation …
Application of graphene quantum dots in heavy metals and pesticides detection
2020
Graphene Quantum Dots (GQDs) were produced using electrochemical oxidation of graphite rods. Obtained GQDs were gamma-irradiated in the presence of the N atoms source, ethylenediamine. Both structural and morphological changes were investigated using UV-Vis, X-ray photoelectron and photoluminescence (PL) spectroscopy as well as atomic force microscopy. The ability of both types of dots to change PL intensity in the presence of pesticides such as malathion and glyphosate, as well as copper (II) ions was detected. These preliminary results indicated a high potential of produced GQDs to be applied as non-enzymatic PL sensors for the detection of selected pesticides and metal ions. 26th Interna…
Fabrication of Graphene Field Effect Transistors (GFET) possessing a photoelectrical response
2014
Graphene oxide surface functionalization of polymeric scaffolds for the recruitment and thermal ablation of tumor cells
2017
Electrical and optical properties of Graphene Field-Effect Transistors (GFETs) fabricated on sapphire
Fabrication and characterization of graphene field effect transistors (GFET)
2015
Graphene is a flat monolayer of carbon atoms tightly packed into a two-dimensional (2D) honeycomb lattice. This peculiarity is responsible of extraordinary physical properties. Graphene exhibits a strong ambipolar field effect and thanks to its huge charge carrier mobility, graphene is a suitable material for high frequency Electronics. Graphene field effect transistors (GFET) for high frequency applications have recently received much attention and significant progress has been achieved in this area. GFETs have been already made by using pre-patterned metal or graphene nanoribbon (GNR) back-gates and hexagonal boron nitride as a dielectric spacer. Among the most employed techniques for the…
Fabrication and analysis of the layout impact in Graphene Field Effect Transistors (GFETs)
2016
In this work we focused on the analysis of Graphene Field Effect Transistor (GFET) microwave parameters dependence on geometries. In particular, a statistical, experimental investigation of the cut-off frequency (ft) dependency on both the gate-drain/source distance (Δ) and the gate length (Lg) was carried out. 24 GFET families on the same chip were fabricated, each one made of 10 identical (same geometry) devices. The analysis of the measured data shows that ft is both Δ and Lg dependent, and that there exists an optimal region in Δ and Lg design space.