Search results for "Rating"
showing 10 items of 2021 documents
The Stroke Riskometer (TM) App: Validation of a data collection tool and stroke risk predictor
2014
Background The greatest potential to reduce the burden of stroke is by primary prevention of first-ever stroke, which constitutes three quarters of all stroke. In addition to population-wide prevention strategies (the ‘mass’ approach), the ‘high risk’ approach aims to identify individuals at risk of stroke and to modify their risk factors, and risk, accordingly. Current methods of assessing and modifying stroke risk are difficult to access and implement by the general population, amongst whom most future strokes will arise. To help reduce the burden of stroke on individuals and the population a new app, the Stroke Riskometer™, has been developed. We aim to explore the validity of the app fo…
Vasoactive peptide urotensin II in plasma is associated with cerebral vasospasm after aneurysmal subarachnoid hemorrhage and constitutes a potential …
2019
National audience; OBJECTIVECerebral vasospasm (VS) is a severe complication of aneurysmal subarachnoid hemorrhage (SAH). Urotensin II (UII) is a potent vasoactive peptide activating the urotensin (UT) receptor, potentially involved in brain vascular pathologies. The authors hypothesized that UII/UT system antagonism with the UT receptor antagonist/biased ligand urantide may be associated with post-SAH VS. The objectives of this study were 2-fold: 1) to leverage an experimental mouse model of SAH with VS in order to study the effect of urotensinergic system antagonism on neurological outcome, and 2) to investigate the association between plasma UII level and symptomatic VS after SAH in huma…
Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance
2022
Background & Aims Serum microRNA (miRNA) levels are known to change in non-alcoholic fatty liver disease (NAFLD) and may serve as useful biomarkers. This study aimed to profile miRNAs comprehensively at all NAFLD stages. Methods We profiled 2,083 serum miRNAs in a discovery cohort (183 cases with NAFLD representing the complete NAFLD spectrum and 10 population controls). miRNA libraries generated by HTG EdgeSeq were sequenced by Illumina NextSeq. Selected serum miRNAs were profiled in 372 additional cases with NAFLD and 15 population controls by quantitative reverse transcriptase PCR. Results Levels of 275 miRNAs differed between cases and population controls. Fewer differences were seen wi…
Optimization of surface plasmons launching from subwavelength hole arrays: modelling and experiments
2009
International audience; The launching of surface plasmons by micro-gratings of subwavelength apertures milled in a thick metal film is important for the development of surface plasmon based circuits. By comparing the near-field optical images of such surface plasmon sources with the results of a Huygens-Fresnel principle based scattering model, we show that the properties of the locally launched SP beams such as divergence or uniformity can be tuned by adjusting the shape of the micro-gratings. This allows us to propose an optimized source array well adapted for providing a narrow, collimated and uniform beam. (c) 2007 Optical Society of America.
In vitro perception of low-contrast features in digital, film, and digitized dental radiographs: A receiver operating characteristic analysis
2005
Objective To compare experimentally the image quality of charged-coupled device (CCD)-based digital, flatbed scanner digitized, and dental film radiographs. Study design High-contrast standardized radiographs of an aluminum step wedge containing boreholes were obtained on dental radiographic film (F) and a CCD receptor (D). Digitization (S) was done with a flatbed scanner. Each radiograph was separated into 23 single images, 18 of which showed a dark spot. Thirty observers indicated their confidence on the visibility of the spots for a receiver operating characteristic (ROC) analysis. Results Mean Az values (area beneath the ROC curves) differed significantly (P < .05), being highest for D …
On Obtaining Classification Confidence, Ranked Predictions and AUC with Tsetlin Machines
2020
Tsetlin machines (TMs) are a promising approach to machine learning that uses Tsetlin Automata to produce patterns in propositional logic, leading to binary (hard) classifications. In many applications, however, one needs to know the confidence of classifications, e.g. to facilitate risk management. In this paper, we propose a novel scheme for measuring TM confidence based on the logistic function, calculated from the propositional logic patterns that match the input. We then use this scheme to trade off precision against recall, producing area under receiver operating characteristic curves (AUC) for TMs. Empirically, using four real-world datasets, we show that AUC is a more sensitive meas…
The Impact of Inattention, Hyperactivity/Impulsivity Symptoms, and Executive Functions on Learning Behaviors of Children with ADHD
2017
Children diagnosed with attention deficit/hyperactivity disorder (ADHD) are at risk of experiencing lower academic achievement compared to their peers without ADHD. However, we have a limited understanding of the mechanisms underlying this association. Both the symptoms of the disorder and the executive functions can negatively influence learning behaviors, including motivation, attitude toward learning, or persistence, key aspects of the learning process. The first objective of this study was to compare different components of learning behaviors in children diagnosed with ADHD and typically developing (TD) children. The second objective was to analyze the relationships among learning behav…
Geochemical and Petrographic Characterization of Marine-Continental Transitional Facies Shale (Qilian Basin, China): Origin of Organic Matter Input, …
2021
This study, for the first time, investigates the source, keroger pattern, evolution degree, sedimentary environment, and evaluates the hydrocarbon generating ability of marine-continental transitional facies shale from the Ebao area of the Qilian Basin in western China. The organic-rich shales of the marine-continental transitional facies were subjected to total organic carbon (TOC), rock pyrolysis, the biomarkers and kerogen microscopy analyses. The kerogen microscopy analyses indicated that the sample from ZK001 well and ZK2002 well had a mass of vitrinite and small number of exinite, so kerogen type was mainly humic. According to vitrinite reflectance, the organic matter was in the stage…
Moment Generating Functions and Central Moments
2018
This section deals with the moment generating functions (m.g.f.) up to sixth order of some discretely defined operators. We mention the m.g.f. and express them in expanded form to obtain moments, which are important in the theory of approximation relevant to problems of convergence.
Mapping Economic Activity in the European Union: Do Ownership, Industry and Location Matter?
2020
The paper proposes a new method for analysing the structure and dynamics of economic activity undertaken by locally owned and foreign-owned companies within the European Union. We employ an unsupervised learning algorithm that generates a neural network depicted on Kohonen maps and offering a clustering of companies with a different ownership (local and foreign) from various industries and countries of the European Union during 2009–2016. The research methodology, based on a self-organizing map (SOM) algorithm, belongs to a class of neural networks trained to organize data so that unknown patterns may be discovered, thus leading to results that cannot be attained by more traditional cluster…