Search results for "Rating"

Monoclonal TCR mRNA transcripts are preferentially detected in the TCR variable alpha chain in CD8(+) T-lymphocytes: implications for immunomonitorin…

1999

Clinical trials have started to implement tumor-associated antigens in the form of antigenic peptides in order to augment CD8(+) T-cell responses directed against autologous cancer cells. One of the surrogate markers for successful immunization is the characterization of T-lymphocytes reacting to the immunizing peptide as determined by CDR3-length and DNA-sequence analysis. Most of the recent studies examining ex vivo T-cell responses in patients with cancer have focussed on expression and prevalence of the TCR Beta variable region, predominantly in non-sorted T-cell populations. Here, we show that clonal T-cell receptors (TCRs), as defined by DNA-fragment analysis and DNA-sequencing, appea…

How credit ratings affect sovereign credit risk: cross-border evidence in Latin American emerging markets

2017

This article builds upon previous literature by providing a better understanding of how contagion changes in bordering sovereign CDS emerging markets resulting from credit rating events. To that end, we follow the novel GVAR methodology using data from six Latin American emerging countries during an extensive sample period from 2004 to 2014. Our findings show evidence for the existence of significant and asymmetric cross-border effects. In particular, a competition effect is observed before the event occurs, indicating that non-event countries suffer (benefit) from upgrades (downgrades) in Brazil, Mexico and Chile (in Argentina and Brazil). In contrast, an imitation effect is observed after…

Do sovereign ratings cause instability in cross-border emerging CDS markets?

2020

We analyse the cross-border transmission effect of credit ratings on sovereign CDSs covering a broad sample of emerging countries during the period 2004 to 2015. This study differentiates between the spillover and competition effects between and within geographical areas of emerging countries. We find substantial evidence of cross-border effects with asymmetric responses to upgrades and downgrades. The market reaction differs across regions, reflecting how the international and local impact of rating events are due to different types of effects. At the international portfolio level, the competitive effect is dominant over the spillover effect. Negative events in Asia benefit Africa (which i…

Predictability, chaos and coordination in bird vigilant behaviour

1999

Revisiting Bicausative Matrices: The Swiss Cheese of Chaos

2009

This paper returns to de Mesnard's paper of 2000, which has exposed the so-called method of bicausative matrices. This method was created to analyze the structural change between two matrices, as an improvement of the causative method of Jackson and al. (1990). In its 2000 paper, de Mesnard has shown that chaos affects the bicausative method: two solutions are found with a brutal switching between both. This new paper demonstrates that the chaos can be largely circumvented, is essentially localized in a small interval and is only a transitory effect between two non-chaotic "regimes", is not always observed, is limited to relatively small matrices.

FILTERING CHAOS: A TECHNIQUE TO ESTIMATE DYNAMICAL AND OBSERVATIONAL NOISE IN NONLINEAR SYSTEMS

2005

Nonlinear dynamical models are frequently used to approximate and predict observed physical, biological and economic systems. Such models will be subject to errors both in the model dynamics, and the observations of the underlying system. In order to improve models, it is necessary to understand the causes of error growth. A complication with chaotic models is that small errors may be amplified by the model dynamics. This paper proposes a technique for estimating levels of both dynamical and observational noise, based on the model drift. The method is demonstrated for a number of models, for cases with both stochastic and nonstochastic dynamical errors. The effect of smoothing or treating …

Construction of pseudo-random sequences from chaos

2002

Extracorporeal shock waves increase markers of cellular proliferation in primary bronchial fibroblasts of COPD patients

2019

COPD is due to a remodeling of small airways and destruction of the lung parenchyma with loss of the alveolar attachment as a result of pulmonary emphysema. Treatment of connective tissue fibroblasts with extracorporeal shock waves (ESW) increases their cellular proliferation and differentiation. To date no studies are available on ESW treatment of human primary bronchial fibroblasts from COPD and control subjects. Primary bronchial fibroblasts were obtained from bronchial biopsies from three patients with mild/moderate COPD and 3 control smokers with normal lung function. After stabilization for 24h, 1 ml of cell suspension (106 cells) from COPD and controls was treated in 2 ml tubes with …

Reliability of numerical models for simulating galvanic corrosion processes

2012

International audience; Maturity of numerical simulation represents an important issue in the development of predictive models of galvanic corrosion. As widely used in electrochemical engineering, a coupled electrochemical-transport-reaction (CETR) model is recommended to simulate the current distribution above a galvanic corrosion cell made of the cut-edge of a galvanized steel sheet. Nevertheless, simulating current density distributions obtained experimentally by scanning vibrating electrode technique (SVET) above such a galvanic cell appears to be more accurate using an electrostatic model considering a homogeneous conductivity. In this case, the absence of concentration gradients next …

The Association of Body Image Self-Discrepancy With Female Gender, Calorie-Restricted Diet, and Psychological Symptoms Among Healthy Junior High Scho…

2021

Background: Body image self-discrepancy reflects a preference for weight loss regardless of normal body size and is a distorted cognition that may be a precursor to eating disorders. The aim of this study was to investigate factors associated with body image self-discrepancy among healthy junior high school students in Japan.Method: This cross-sectional study was conducted at one junior high school in Saitama, Japan, in December 2016. After excluding obese participants (defined as 20% above their ideal weight), 304 students (mean age, 13.9years; n=181 girls, 59.5%) who fell into underweight (n=22, 7.2%) and normal weight categories were selected. Body image self-discrepancy was measured usi…