Search results for "Ray"

showing 10 items of 8009 documents

Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex

2014

Highlights • We characterise Sas3p and Gcn5p active HAT complexes in WT and deleted TAP-strains. • We confirm that Pdp3p interacts with NuA3, histones and chromatin regulators. • Pdp3p MS-analysis reveals its phosphorylation, ubiquitination and methylation. • Sas3p can substitute Gcn5p in acetylation of histone H3K14 but not of H3K9. • Genome-wide profiling of Sas3p supports its involvement in transcriptional elongation.

nt nucleotidePTM post-translational modificationNuA3 histone acetyltransferase complexChIP-on-chip chromatin immunoprecipitation with genome-wide location arraysBiologyArticleGeneral Biochemistry Genetics and Molecular BiologyChromatin remodelingHistonesHistone H3NuA3 nucleosomal acetyltransferase of histone H3Histone H1Histone H2APdp3TAP–MS strategyHistone codelcsh:QH301-705.5TAP tandem affinity purificationGeneticsRNAPII RNA polymerase IIHistone acetyltransferaseWCE whole cell extractSAGA Spt-Ada-Gcn acetyltransferaseWT wild-typeChromatinYeastCell biologyChIP-on-chiplcsh:Biology (General)Histone methyltransferasebiology.proteinHAT histone acetyltransferaseTSS transcription start siteFEBS Open Bio
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Spectroscopic studies of 173Pt and 175Pt

2014

nuclear spectroscopycranked shell modelgamma-ray spectroscopyalpha decayneutron-deficient nucleirecoil-decay tagging
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Spectroscopy of [sub 199,201]At

2015

The excited states of 199At and 201At were studied using fusion evaporation reactions, a gas-filled recoil separator and various tagging methods. The level scheme of 201At was extended a lot including a cascade of magnetic dipole transitions, that is suggested to form a shears band. In addition, a 29/2+ [T1/2 = 3.39(9) s] isomeric state was observed. The 29/2+ state is suggested to originate from the p(h9/2) j200Po; 11􀀀i configuration, and it depopulates through 269-keV E2 and 339-keV E3 transitions. In both nuclei 199,201At we have observed also the isomeric 1/2+ [T1/2 = 273(9), 45(3) ms, respectively] intruder state, that is suggested to originate from the p(s1/2)􀀀1 configuration. The 1…

nuclear spectroscopyisotoopitastatiinishears bandnuclear structurespektroskopianeutron-deficient nucleiγ-ray spectroscopyrecoil-decay taggingydinfysiikka
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Tracer migration in crystalline rock : application to geological barriers of nuclear waste storage

2016

This work deals with transport of radionuclides in the geosphere. The subject is investigated through characterisation of water conducting fractures, determining of rock transport properties and development of new methods for characterising geological samples. Here, as is often the case, radionuclide transport is investigated indirectly by characterising the structures, where the transport takes place, and directly by measuring transport properties in the gas phase. First water conducting fractures of three different types and the rock matrix surrounding them were analysed through rock samples from Olkiluoto. The analysis was done using X-ray tomography, the 14C-PMMA autoradiography techniq…

nuclear wasteperuskalliocrystalline rockdiffusionEurajokiautoradiografiamerkkiaineetläpäisevyysloppusijoitusfracturesautoradiographykulkeutuminendeep geological repositoriesradioaktiiviset aineethuokoisuusydinjätteetmurtumattransport propertiestomografiakallioperäX-ray tomographykivi
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Single-Center-Single-Blinded Clinical Trial to Evaluate the Efficacy of a Nutraceutical Containing Boswellia Serrata, Bromelain, Zinc, Magnesium, Hon…

2022

Some nutraceuticals have been studied as supportive treatment for fighting upper respiratory tract infection and middle ear disease. Our study aims at evaluating the effect of a specific oral supplementation in the treatment of pediatric otits media. The subjects were randomly assigned by the physician (single-blinded study) to one of three groups: Control Group (CG), Treatment Group 1 (TG1), or Treatment Group 2 (TG2). Both TG were treated with Flogostop Duo (for 20 days—TG1 or 30 days—TG2) in combination with the standard treatment, while CG underwent standard treatment only. The standard treatment was nasal aerosol with Fluticasone and Mucolytic, and nasal washing with hypertonic solutio…

nutraceuticalsLeadership and ManagementHealth Policyauditory testbromelainclinical trialHealth Informaticsnasal spraynutraceuticals; clinical trial; Boswellia; bromelain; upper respiratory infection; Otitis Media; auditory test; nasal spray; quality of lifeOtitis Mediaquality of lifeHealth Information ManagementBoswelliaupper respiratory infectionHealthcare
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Anti-inflammatory properties of an aldehydes-enriched fraction of grapefruit essential oil

2023

Chronic inflammation is linked to the development of numerous diseases and is accompanied by increased cytokine secretion. Macrophages provide a first line of defense against pathogens that under inflammatory stimuli release pro-inflammatory cytokines. The essential oil (EO) fractions obtained from Citrus spp. rich in different compounds have gained the attention of both researchers and users during the last decades. In particular, grapefruit (Citrus paradisi) peel is rich in phenolics and flavonoids with several health benefits, including anti-inflammatory actions. Additionally, its EO consists of a large number of compounds such as monoterpenes, sesquiterpenes, alcohols, aldehydes, esters…

nutraceuticalsspray-dryinflammationSettore BIO/13 - Biologia Applicataaldehydescitralessential oilFood ScienceCitrus paradisi
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Fundamental movement skill proficiency and body composition measured by dual energy X-ray absorptiometry in eight-year-old children

2014

Objective: The main aim was to examine the association between fundamental movement skills (FMS) and objectively measured body composition using dual energy X-ray absorptiometry (DXA). Methods: Study of 304 eight-year-old children in Finland. FMS were assessed with the Test of Gross Motor Development, 2nd ed. (TGMD-2). Total body fat percentage (BF%), abdominal region fat percentage (AF%), and fat-free mass (FFM) were assessed by DXA. Waist circumference, height and weight were measured and International Obesity Task Force (IOTF) cut-off values for BMI were used for the definition of healthy weight and overweight/obesity. Results: Better FMS proficiency (object-control, locomotor, total FMS…

obesitymedicine.medical_specialtyWaistSocial PsychologyGross motor skillruumiinrakenne030209 endocrinology & metabolismOverweightPediatricsliikalihavuus03 medical and health sciences0302 clinical medicineClassification of obesityDevelopmental and Educational Psychologymedicineoverweightta315motoriset taidotfundamental movement skillsDual-energy X-ray absorptiometrykehonkoostumusDXAbody compositionmedicine.diagnostic_testmotor skillsylipaino030229 sport sciencesmedicine.diseaseCircumferenceObesityPhysical therapylihavuusmedicine.symptomPsychologyBody mass indexEarly Child Development and Care
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HAWC Gamma-Ray survey, AGNs at TeV photon energies

2022

The High Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory continuously detects TeV photons and particles within its large field of view, accumulating every day a deeper exposure of two-thirds of the sky. We analyzed 1523days of HAWC live data acquired over four and a half years, in a follow-up analysis of 138 nearby (z<0.3) active galactic nuclei from the Third Catalog of Hard Fermi-LAT sources culminating within 40{deg} of the zenith at Sierra Negra, the HAWC site. This search for persistent TeV emission used a maximum- likelihood analysis assuming intrinsic power-law spectra attenuated by pair production of gamma-ray photons with the extragalactic background light. HAWC clearly detec…

observational astronomyActive galactic nucleigalactic and extragalactic astronomyAstrophysics and AstronomyGamma-ray astronomyhigh energy astrophysicsPhysicsGamma ray astronomySurveysNatural Sciences
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Neutrinos from GRBs with ANTARES

2013

A search for muon neutrinos in coincidence with gamma-ray bursts with the ANTARES neutrino detector using data from the end of 2007 to 2011 is performed. Expected neutrino fluxes are calculated for each burst individually. The most recent numerical calculations of the spectra using the NeuCosmA code are employed, which include Monte Carlo simulations of the full underlying photohadronic interaction processes. The discovery probability for a selection of 296 gamma-ray bursts in the given period is optimised using an extended maximum-likelihood strategy. No significant excess over background is found in the data, and 90% confidence level upper limits are placed on the total expected flux acco…

observational astronomyAstronomical modelsAstrophysics and AstronomyGamma-ray astronomyPhysics::Instrumentation and DetectorsPhysicsAstrophysics::High Energy Astrophysical PhenomenaGamma ray astronomyAstrophysics::Instrumentation and Methods for AstrophysicsHigh Energy Physics::ExperimentNatural Sciences
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3rd HAWC cat. of VHE gamma-ray sources (3HWC)

2022

We present a new catalog of TeV gamma-ray sources using 1523 days of data from the High-Altitude Water Cherenkov (HAWC) Observatory. The catalog represents the most sensitive survey of the northern gamma-ray sky at energies above several TeV, with three times the exposure compared to the previous HAWC catalog, 2HWC. We report 65 sources detected at >=5{sigma} significance, along with the positions and spectral fits for each source. The catalog contains eight sources that have no counterpart in the 2HWC catalog, but are within 1{deg} of previously detected TeV emitters, and 20 sources that are more than 1{deg} away from any previously detected TeV source. Of these 20 new sources, 14 have a p…

observational astronomyAstrophysics and AstronomyGamma-ray astronomyPhysicsGamma ray astronomyNatural Sciences
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