Search results for "Rays"

showing 10 items of 1136 documents

A NANOPARTICULATE DRUG-DELIVERY SYSTEM FOR RIVASTIGMINE: PHYSICO-CHEMICAL AND IN VITRO BIOLOGICAL CHARACTERIZATION

2007

The preparation and characterization of surface-PE Gylated polymeric nanoparticles are described. These systems were obtained by UV irradiation of PHM and PHM-PEG(2000) as an inverse microemulsion, using an aqueous solution of the PHM/PHM-PEG(2000) copolymer mixture as the internal phase and triacetin saturated with water as the external phase, and characterized by dimensional analysis, zeta-potential measurements and XPS. in vitro biological tests demonstrated their cell compatibility and their ability to escape from phagocytosis. Rivastigmine was encapsulated into the nanoparticle structure and drug-release profiles from loaded samples were investigated in PBS at pH = 7.4 and human plasma.

Molecular StructureCell SurvivalUltraviolet RaysPhenylcarbamatesRivastigmineHemolysisPolyethylene GlycolsPOLYMERIC NANOPARTICLES RIVASTIGMINE DRUG DELIVERYDrug Delivery SystemsPolymethacrylic AcidsSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoCell Line TumorDelayed-Action PreparationsHumansNanoparticlesPeptidesTriacetin
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Synthesis and evaluation of diverse thio avarol derivatives as potential UVB photoprotective candidates.

2007

Semisynthesis of 13 new thio avarol derivatives (4-16) and in vitro evaluation on the photodamage response induced by UVB irradiation are described. Their ability to inhibit NF-kappaB activation and TNF-alpha generation in HaCaT cells as well as their antioxidant capacity in human neutrophils has also been studied. Among them we have identified two monophenyl thio avarol derivatives (4-5) lacking cytotoxicity which can be considered promising UVB photoprotective agents through the potent inhibition of NF-kappaB activation with a mild antioxidant pharmacological profile.

AntioxidantMagnetic Resonance SpectroscopyNeutrophilsPhotochemistryUltraviolet Raysmedicine.medical_treatmentChemistry PharmaceuticalClinical BiochemistryMolecular ConformationPharmaceutical ScienceThio-BiochemistryChemical synthesisAntioxidantsCell Line TumorDrug DiscoverymedicineHumansCytotoxicityMolecular Biologyintegumentary systemChemistryTumor Necrosis Factor-alphaOrganic ChemistryNF-kappa BSemisynthesisIn vitroHaCaTmedicine.anatomical_structureBiochemistryModels ChemicalDrug DesignMolecular MedicineKeratinocyteReactive Oxygen SpeciesSesquiterpenesBioorganicmedicinal chemistry letters
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Live demonstration: multiplexing AER asynchronous channels over LVDS Links with Flow-Control and Clock-Correction for Scalable Neuromorphic Systems

2017

Paper presented at the 2017 IEEE International Symposium on Circuits and Systems (ISCAS), held in Baltimore, MD, USA, on 28-31 May 2017.

Computer scienceSerial communicationGabor filters02 engineering and technologyMultiplexingMultiplexing0202 electrical engineering electronic engineering information engineeringComputerSystemsOrganization_SPECIAL-PURPOSEANDAPPLICATION-BASEDSYSTEMSField-programmable gate arrayComputer Science::Operating SystemsMassively parallelNeuromorphicsReal-time systemsSpiking neural networkQuantitative Biology::Neurons and CognitionArtificial neural networkbusiness.industry020208 electrical & electronic engineeringField programmable gate arraysNeuromorphic engineeringAsynchronous communicationEmbedded systemVoltage controlbusinessComputer hardwareNeural networksHardware_LOGICDESIGN
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Spin up and phase fluctuations in the timing of the accreting millisecond pulsar XTE J1807-294

2007

We performed a timing analysis of the 2003 outburst of the accreting X-ray millisecond pulsar XTE J1807-294 observed by RXTE. Using recently refined orbital parameters we report for the first time a precise estimate of the spin frequency and of the spin frequency derivative. The phase delays of the pulse profile show a strong erratic behavior superposed to what appears as a global spin-up trend. The erratic behavior of the pulse phases is strongly related to rapid variations of the light curve, making it very difficult to fit these phase delays with a simple law. As in previous cases, we have therefore analyzed separately the phase delays of the first harmonic and of the second harmonic of …

Orbital elementsPhysicsAstrophysics::High Energy Astrophysical PhenomenaAstrophysics (astro-ph)Phase (waves)Static timing analysisFOS: Physical sciencesAstronomy and AstrophysicsAstrophysicsLight curveAstrophysicsPulsars: General Stars: Pulsars: Individual: Alphanumeric: XTE J1807-294 Stars: Magnetic Fields Stars: Neutron X-Rays: Binaries [Stars]Pulse (physics)Settore FIS/05 - Astronomia E AstrofisicaSpace and Planetary ScienceMillisecond pulsarHarmonicStars: Pulsars: General Stars: Pulsars: Individual: Alphanumeric: XTE J1807-294 Stars: Magnetic Fields Stars: Neutron X-Rays: BinariesSpin-½
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New Pre-Main Sequence Candidates in the Taurus-Auriga Star Forming Region

2007

Aims. We have studied the X-ray source population of the Taurus Molecular Cloud (TMC) to search for new members of the Taurus-Auriga star forming region. Methods. Candidate members have been selected among the X-ray sources detected in 24 fields of the XMM-Newton Extended Survey of the Taurus Molecular Cloud, having an IR counterpart in the 2MASS catalog, based on color-magnitude and color-color diagrams. Their X-ray spectral properties have been compared with those of known members and other X-ray sources in the same fields but without a NIR counterpart. A search for flare-like variability in the time series of all new candidates and the analysis of the X-ray spectra of the brightest candi…

010504 meteorology & atmospheric sciencesStellar massAstrophysics::High Energy Astrophysical PhenomenaAstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsGalaxy : open clusters and associations : individual : Taurus Molecular Cloud01 natural sciences[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO]stars : activitystars : pre-main-sequence0103 physical sciencesstars : luminosity function mass functionAstrophysics::Solar and Stellar Astrophysics010303 astronomy & astrophysicsLuminosity functionAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesPhysicsAURIGAMolecular cloudAstronomyAstronomy and AstrophysicsLight curveStarsStar clusterSpace and Planetary Science[PHYS.ASTR.CO] Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO]X-rays : starAstrophysics::Earth and Planetary Astrophysicsstars : coronaeOpen cluster
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Multi Parametric Advanced Research tool for meteo satellite data interfacing with space observation of Ultra High Energy Cosmic Rays.

2006

To approach the study of the cosmic rays in the energy range E > 10 20 eV, the upper end of the spectrum observed to date, with a large statistical significance (103 events/year), and hence address the solution of several astrophysical and cosmological problems related to their existence and behaviour, a new generation of experiments will probably have to be conceived and realised. They will be based on the observation and measurements of cosmic rays from space. The extremely low rate of these events (∼ 1 event/(century × km2 × sr)) imposes a very large effective area to be monitored, of the order of 105km2, as an observational requirement to meet the target statistics. The Extreme Universe…

cosmic raysrays UHECRsenergy
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Long-term monitoring of mrk 501 for its very high energy γ emission and a flare in 2011 october

2012

"As one of the brightest active blazars in both X-ray and very high energy γ -ray bands, Mrk 501, is very useful for" "physics associated with jets from active galactic nuclei. The ARGO-YBJ experiment has monitored Mrk 501 for γ - rays above 0.3 TeV since 2007 November. The largest flare since 2005 was observed from 2011 October and lasted until about 2012 April. In this paper, a detailed analysis of this event is reported. During the brightest γ -ray flaring episodes from 2011 October 17 to November 22, an excess of the event rate over 6σ is detected by ARGO-YBJ in the direction of Mrk 501, corresponding to an increase of the γ -ray flux above 1 TeV by a factor of 6.6 ± 2.2 from its steady…

Active galactic nucleusactive" ["galaxies]Astrophysics::High Energy Astrophysical PhenomenaFluxAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics7. Clean energy01 natural sciencesSpectral linelaw.inventionlaw0103 physical sciencesBlazar010303 astronomy & astrophysicsPhysicsindividual (Markarian 501) – galaxies: active – gamma rays: general – radiation mechanisms: non-thermal [BL Lacertae objects]" "general" ["gamma rays]010308 nuclear & particles physicsBL Lacertae objects: individual (Markarian 501) – galaxies: active – gamma rays: general – radiation mechanisms: non-thermalSettore FIS/01 - Fisica SperimentaleAstronomy and AstrophysicsQuasarGalaxyindividual (Markarian 501)" ["BL Lacertae objects]13. Climate actionSpace and Planetary ScienceSpectral energy distributionFlare
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Bio-metal-organic frameworks for molecular recognition and sorbent extraction of hydrophilic vitamins followed by their determination using HPLC-UV

2020

A bio-metal-organic framework (bio-MOF) derived from the amino acid L-serine has been prepared in bulk form and evaluated as sorbent for the molecular recognition and extraction of B-vitamins. The functional pores of bio-MOF exhibit high amounts of hydroxyl groups jointly directing other supramolecular host-guest interactions thus providing the recognition of B-vitamins in fruit juices and energy drinks. Single-crystal X-ray diffraction studies reveal the specific B-vitamin binding sites and the existence of multiple hydrogen bonds between these target molecules and the framework. It offered unique snapshots to accomplish an efficient capture of these solutes in complex aqueous matrices. Fo…

Detection limitVitaminesSorbentChromatographySurface PropertiesUltraviolet RaysElutionChemistryHydrophilic interaction chromatography010401 analytical chemistryExtraction (chemistry)Supramolecular chemistryQuímica analítica010402 general chemistry01 natural sciences0104 chemical sciencesAnalytical ChemistryBegudesMolecular recognitionVitamin B ComplexAdsorptionSolid phase extractionParticle SizeHydrophobic and Hydrophilic InteractionsMetal-Organic FrameworksMicrochimica Acta
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The X-ray emission mechanism in the protostellar jet HH 154

2004

We study the mechanism causing the X-ray emission recently detected in protostellar jets, by performing a detailed modeling of the interaction between a supersonic jet originating from a young stellar object and the ambient medium, for various values of density contrast, ν, between the ambient density and the jet, and of Mach number, M; radiative losses and thermal conduction have been taken into account. Here we report a representative case which reproduces, without any ad hoc assumption, the characteristics of the X-ray emission recently observed in the protostellar jet HH 154. We find that the X-ray emission originates from a localized blob, consistent with observations, which moves with…

PhysicsJet (fluid)Proper motionAstrophysics::High Energy Astrophysical PhenomenaYoung stellar objectAstronomy and AstrophysicsAstrophysicsThermal conductionISM: Herbig-Haro objects ISM: individual objects: HH 154 ISM: jets and outflows X-rays: ISMSpace and Planetary ScienceRadiative transferSupersonic speedHerbig–Haro objectDensity contrastAstrophysics::Galaxy Astrophysics
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Characterization of the ESR response of alanine dosimeters to low-energy (1-40 keV) X-rays

2016

The aminoacid L-a-alanine has attracted considerable interest for use in radiation ESR dosimetry and has been formally accepted as a secondary standard for high-dose (kGy) and transfer dosimetry . The accuracy of the method is quite high, largely due to the low dependence of the alanine response on various irradiation parameters (photon energies above 100 keV, dose rate, temperature, etc.). Furthermore, this system presents alinear response to dose, fairly high sensitivity, tissue equivalence, absence of fading, small dimensions, ruggedn ess, and non-destructive readout. In this work, we examined the energy dependence of alanine ESR dosimeters in the low energy X-photon energy range between…

Settore ING-IND/20 - Misure E Strumentazione NucleariESR EPR Alanine Low-energy X-rays LAXSettore FIS/01 - Fisica SperimentaleSettore FIS/03 - Fisica Della MateriaSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)
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