Search results for "Reactants"
showing 3 items of 3 documents
Mechanistic insights into the phosphoryl transfer reaction in cyclin-dependent kinase 2: a QM/MM study
2019
AbstractCyclin-dependent kinase 2 (CDK2) is an important member of the CDK family exerting its most important function in the regulation of the cell cycle. It catalyzes the transfer of the gamma phosphate group from an ATP (adenosine triphosphate) molecule to a Serine/Threonine residue of a peptide substrate. Due to the importance of this enzyme, and protein kinases in general, a detailed understanding of the reaction mechanism is desired. Thus, in this work the phosphoryl transfer reaction catalyzed by CDK2 was revisited and studied by means of hybrid quantum mechanics/molecular mechanics (QM/MM) calculations. Our results show that the base-assisted mechanism is preferred over the substrat…
Magnetic Field Control of Combustion Dynamics
2016
Abstract Experimental studies and mathematical modelling of the effects of magnetic field on combustion dynamics at thermo-chemical conversion of biomass are carried out with the aim of providing control of the processes developing in the reaction zone of swirling flame. The joint research of the magnetic field effect on the combustion dynamics includes the estimation of this effect on the formation of the swirling flame dynamics, flame temperature and composition, providing analysis of the magnetic field effects on the flame characteristics. The results of experiments have shown that the magnetic field exerts the influence on the flow velocity components by enhancing a swirl motion in the …
Control of the Development of Swirling Airflow Dynamics and Its Impact on Biomass Combustion Characteristics
2017
Abstract The development of the swirling flame flow field and gasification/ combustion dynamics at thermo-chemical conversion of biomass pellets has experimentally been studied using a pilot device, which combines a biomass gasifier and combustor by varying the inlet conditions of the fuel-air mixture into the combustor. Experimental modelling of the formation of the cold nonreacting swirling airflow field above the inlet nozzle of the combustor and the upstream flow formation below the inlet nozzle has been carried out to assess the influence of the inlet nozzle diameter, as well primary and secondary air supply rates on the upstream flow formation and air swirl intensity, which is highly …