Search results for "Reaction"

showing 10 items of 6134 documents

Do children with overweight respond faster to food-related words?

2020

Abstract Overweight in childhood is a risk factor in developing obesity as an adult, thus having severe consequences on the individuals’ physical health and psychological well-being. Therefore, studying the cognitive and emotional processes that sustain overweight is essential not only at a theoretical level but also to develop effective interventions. In the present experiment, we examined whether children with overweight respond faster to food-related than non-food-related words in a word recognition task: lexical decision. The participants were 24 children diagnosed with exogenous overweight and 24 children with a healthy weight. The stimulus list included positively valenced food-relate…

Adult0301 basic medicinePediatric ObesityEmotionsWord processing030209 endocrinology & metabolismOverweightStimulus (physiology)Developmental psychology03 medical and health sciences0302 clinical medicineChildren Food Lexical decision Overweight Word recognitionReaction TimemedicineLexical decision taskHumansRisk factorChildGeneral Psychology030109 nutrition & dieteticsNutrition and Dieteticsdigestive oral and skin physiologyCognitionOverweightmedicine.diseaseObesityWord recognitionmedicine.symptomPsychologyAppetite
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Antibodies to hepatitis B core antigen in blood donors screened for alanine aminotransferase level and hepatitis non-A, non-B in recipients.

1988

Four-hundred and seventeen patients undergoing open-heart surgery were followed for more than 9 months after transfusion. All 2270 blood units transfused had alanine aminotransferase levels less than or equal to 30 U/l. Blood units positive for antibodies to hepatitis B core antigen (anti-HBc) were more frequently associated with recipient hepatitis non-A, non-B (HNANB) (13.7%) than anti-HBc-negative units (4.2%) (p less than 0.001). The frequency of HNANB among recipients of at least 1 anti-HBc-positive blood unit (8/79, 10.1%) was fivefold greater than among recipients of exclusively anti-HBc-negative blood units (7/338, 2.1%) (p less than 0.01). In this study the exclusion of donors posi…

AdultAdolescentHepatitis Viral HumanImmunologyBlood DonorsAntigenImmunology and AllergyMedicineHumansAlanine aminotransferaseHepatitis B AntibodiesAgedHepatitisbiologybusiness.industryIncidence (epidemiology)virus diseasesTransfusion ReactionAlanine TransaminaseHematologyMiddle Agedmedicine.diseaseHepatitis B Core AntigensHepatitis Cdigestive system diseasesImmunologybiology.proteinBlood unitsAntibodybusinessDonor screeningHepatitis b coreTransfusion
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Exploring the reciprocal modulation of time and space in dancers and non-dancers.

2014

We explored whether time and space representations modulate each other in subjects that are trained to integrate time and space dimensions, i.e., professional dancers. A group of dancers, and one of non-dancers, underwent two different tasks employing identical stimuli. A first static central line could last one of three possible durations and could have one of three possible lengths. A second growing line appeared from the left or right of the screen and grew up toward the opposite direction at constant velocity. In the Spatial task, subjects encoded the length of the static line and stopped the growing line when it had reached half the length of the static one, regardless of time travel. …

AdultAdolescentMovementStimulus (physiology)Time travelYoung AdultMultiple time dimensionsReaction TimeSPACEHumansDancingTime processingCommunicationDANCESpacetimeSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicabusiness.industryConstant velocityGeneral NeuroscienceSpace–time interactionHandTIMEMotor SkillsSpace PerceptionTime PerceptionFemaleTime processingbusinessPsychologySpace processingReciprocalCognitive psychologyExperimental brain research
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Diagnostic problems and postnatal follow-up in congenital toxoplasmosis

2007

Aim. In order to assess the consequences of different clinica] approaches in the prenata] management of congenital toxoplasmosis, we retrospectively reviewed 58 pregnant women with Toxoplasma seroconversion and prospec­ tively enrolled their 59 infants, referred to us from 1999 to 2004. Metbods. Data on clinica!, laboratocy and de­ mographic characteristics of the pregnant women were collected. Their children were entered intoa 48-month follow-up progcamme in which clinica , instrumental, ophthalmo­ logic and serologic evaluations were carried out at birth, at 1, 3, 6, 9, 15, 18, 24, 36 and at 48 months of life. Paediatric treatment with Spiramycin alone or alternated with Pyrime­ thamine-S…

AdultAdolescentSettore MED/17 - Malattie InfettiveAntiprotozoal AgentsSulfadiazinePolymerase Chain ReactionToxoplasmosis CongenitalAntimalarialsPregnancyAnimalsHumansProspective StudiesSicilyRetrospective StudiesInfantToxoplasmosis Diagnostic stepsInfectious Disease Transmission VerticalPyrimethamineTreatment OutcomeImmunoglobulin MImmunoglobulin GPregnancy Complications ParasiticAmniocentesisCoccidiostatsDrug Therapy CombinationFemalePregnancy TrimestersBiomarkersFollow-Up Studies
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Emotional interference and attentional processing in premenstrual syndrome

2017

Abstract Background and objectives Premenstrual syndrome (PMS) is characterized by menstrual cycle-related affective, behavioral, and/or somatic symptoms. By applying the emotional Stroop task (EST) the current study examined if changes in processing emotional information, which have been demonstrated in affective disorders, are also present in PMS. Methods Via online screening, telephone interviews, and daily records over two months 55 women for the PMS group (on the basis of the specific inclusion criteria and a prospectively confirmed PMS) and 55 ‘non-PMS’ controls were recruited. All participants completed three emotional Stroop tasks (EST) with neutral and negative word, picture, and f…

AdultAdolescentmedia_common.quotation_subjectExperimental and Cognitive PsychologyLuteal phaseOnline Systems050105 experimental psychologyDevelopmental psychologyPremenstrual SyndromeYoung Adult03 medical and health sciences0302 clinical medicineArts and Humanities (miscellaneous)Reaction TimemedicineHumans0501 psychology and cognitive sciencesYoung adultMenstrual CycleMenstrual cyclemedia_commonAnalysis of VarianceMood Disorders05 social sciencesCognitionmedicine.diseaseMenstrual cycle phasePsychiatry and Mental healthClinical PsychologyMood disordersAttention Deficit Disorder with HyperactivityStroop TestFemaleAnalysis of variancePsychology030217 neurology & neurosurgeryClinical psychologyStroop effectJournal of Behavior Therapy and Experimental Psychiatry
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Comparison of ground reaction forces and antagonist muscle coactivation during stair walking with ageing

2006

Abstract Stair walking is a demanding task in old age. Ground reaction force (GRF) analysis, relative EMG activation, and muscular coactivation were performed during stair walking. The aim was to investigate the ageing effect on GRF distribution and muscle antagonist coactivation during stair walking, at varied speed. During ascending at maximal velocity old subjects demonstrated reduced GRF in all examined phases (range: 28–35%), whereas muscle coactivation only was elevated for the Entire stance phase (18.5%). GRF parameters during ascent and descent at freely chosen speed demonstrated differences between age groups (5–28%). Furthermore, muscle coactivation was elevated in old subjects (e…

AdultAgingmedicine.medical_specialtyAntagonist muscleStair walking Muscle coactivation Reserve capacity AgeingBiophysicsNeuroscience (miscellaneous)Stair walkingWalkingElectromyographyMuscle coactivationPhysical medicine and rehabilitationAge groupsmedicineHumansGround reaction forceMuscle SkeletalAgedmedicine.diagnostic_testElectromyographybusiness.industryCoactivationmedicine.anatomical_structureAgeingFemaleNeurology (clinical)businesshuman activitiesJournal of Electromyography and Kinesiology
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β-Adrenoceptor stimulation up-regulates phosphodiesterase 4 activity and reduces prostaglandin E 2 -inhibitory effects in human neutrophils

2000

Human neutrophils were treated for 4 h with a combination of salbutamol (1 µM), a β2-adrenoceptor agonist, and rolipram (30 µM), a selective phosphodiesterase 4 inhibitor, to investigate whether this treatment produces up-regulation of phosphodiesterase activity with functional consequences. Anion-exchange chromatography coupled with the use of selective activators and inhibitors demonstrated that a phosphodiesterase activity with characteristics of the isoenzyme type 4 was increased in drug-treated cells. Kinetic analysis showed a ~1.5-fold increase in V max without alteration of K m values. The augmented phosphodiesterase activity in drug-treated cells was abolished by actinomycin D. Cycl…

AdultAgonistmedicine.medical_specialtyNeutrophilsmedicine.drug_classStimulationIn Vitro TechniquesBiologyDinoprostoneNeutrophil Activationchemistry.chemical_compoundPDE4BDownregulation and upregulationSuperoxidesInternal medicineCyclic AMPmedicineHumansAlbuterolRNA MessengerEnzyme InhibitorsProstaglandin E2RolipramPharmacologyReverse Transcriptase Polymerase Chain ReactionSuperoxideZymosanZymosanGeneral MedicineAdrenergic AgonistsCyclic Nucleotide Phosphodiesterases Type 4Up-RegulationEndocrinologychemistry3'5'-Cyclic-AMP PhosphodiesterasesReceptors Adrenergic beta-2Roliprammedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Determination of four parabens and bisphenols A, F and S in human breast milk using QuEChERS and liquid chromatography coupled to mass spectrometry

2018

Abstract For the first time, a multiresidue, sensitive and high throughput method for determination of bisphenol A, F and S and 4 parabens (methyl paraben, ethyl paraben, propyl paraben and butyl paraben) in human breast milk was developed. The proposed method includes an extraction and clean-up procedure based on QuEChERS methodology followed by liquid chromatography coupled to triple quadrupole mass spectrometry determination. Negative atmospheric pressure chemical ionization in the selected reaction monitoring mode was used for mass detection. During the method validation the recoveries varied between 83 and 115% with a precision lower than 20% for all analytes using spiked levels from 0…

AdultAnalyteBisphenol AClinical BiochemistryParabensAtmospheric-pressure chemical ionizationMass spectrometryQuechers030226 pharmacology & pharmacy01 natural sciencesBiochemistryMass SpectrometryAnalytical Chemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePhenolsLimit of DetectionLiquid chromatography–mass spectrometryHumansSulfonesBenzhydryl CompoundsChromatographyMilk HumanChemistry010401 analytical chemistrySelected reaction monitoringReproducibility of ResultsCell BiologyGeneral Medicine0104 chemical sciencesParabenLinear ModelsFemaleChromatography LiquidJournal of Chromatography B
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Flexible switching of feedback control mechanisms allows for learning of different task dynamics.

2013

To produce skilled movements, the brain flexibly adapts to different task requirements and movement contexts. Two core abilities underlie this flexibility. First, depending on the task, the motor system must rapidly switch the way it produces motor commands and how it corrects movements online, i.e. it switches between different (feedback) control policies. Second, it must also adapt to environmental changes for different tasks separately. Here we show these two abilities are related. In a bimanual movement task, we show that participants can switch on a movement-by-movement basis between two feedback control policies, depending only on a static visual cue. When this cue indicates that the …

AdultAnatomy and PhysiologyCognitive NeuroscienceMovementFeedback controlNeurophysiologylcsh:MedicineMotor ActivitySocial and Behavioral SciencesNeurological SystemFeedbackMotor ReactionsYoung Adult03 medical and health sciencesLearning and Memory0302 clinical medicineHuman–computer interactionTask Performance and AnalysisMotor systemReaction TimePsychologyLearningHumansMotor activitylcsh:ScienceBiologySensory cue030304 developmental biologyMotor SystemsComputational NeurosciencePhysics0303 health sciencesMultidisciplinarybusiness.industrylcsh:RCognitive PsychologyMotor commandsRoboticsMental HealthArmMedicinelcsh:QArtificial intelligenceCuesbusiness030217 neurology & neurosurgeryHuman learningResearch ArticleNeurosciencePLoS ONE
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Erratum: By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy

2019

Basal-like breast cancer is an aggressive tumor subtype with a poor response to conventional therapies. Tumor formation and relapse are sustained by a cell subset of Breast Cancer Stem Cells (BrCSCs). Here we show that miR-100 inhibits maintenance and expansion of BrCSCs in basal-like cancer through Polo-like kinase1 (Plk1) down-regulation. Moreover, miR-100 favors BrCSC differentiation, converting a basal like phenotype into luminal. It induces the expression of a functional estrogen receptor (ER) and renders basal-like BrCSCs responsive to hormonal therapy. The key role played by miR-100 in breast cancer free-survival is confirmed by the analysis of a cohort of patients' tumors, which sho…

AdultAntineoplastic Agents HormonalTransplantation HeterologousBreast cancer basal-like differentiation miR-100Breast NeoplasmsCell Cycle ProteinsKaplan-Meier EstimateMice SCIDProtein Serine-Threonine KinasesMice Inbred NODCell Line TumorProto-Oncogene ProteinsAnimalsHumansAgedAged 80 and overReverse Transcriptase Polymerase Chain ReactionCorrectionCell DifferentiationMiddle AgedPrognosisImmunohistochemistryGene Expression Regulation NeoplasticMicroRNAsTamoxifenOncologyReceptors EstrogenMCF-7 CellsNeoplastic Stem CellsFemale
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