Search results for "Real Option"

Real Options Analysis (ROA)opens innovation: the biopharmaceutical case

2012

An user friendly Real Options based Model to Optimize Pharmaceutical R&D Portfolio

2013

Pharmaceutical industry pays great attention to its R&D process because it is a long, dynamic, very expensive, and uncertain process. On the other hand this process can be modelled as a step-wise process and each stage allows to achieve better information and generally lower uncertainty. In order to build up the best portfolio a tool able to capture the intrinsic flexible nature of the process should be selected: real options analysis has this characteristic but as widely demonstrated in literature, is narrowed to very limited cases because its perceived complexity. Basing on OptFolio, a model available in literature, this paper proposes an user friendly programming model based on Real Opti…

Open innovation: A real option to restore value to the biopharmaceutical R&D

2014

The pharmaceutical landscape has changed, and new business models, based on alliances, are increasingly being adopted in this industry. Biotechnology advances have pushed this development, and pooling complementary resources coming from incumbents and newcomers is a key skill to succeed: these are the premises for a quick spread of the open innovation (OI) paradigm in this industry. R&D portfolio selection needs R&D project evaluation, and Real Options Analysis (ROA) is acknowledged as a powerful tool to evaluate uncertain projects that have an intrinsic flexibility. The present research aims to foster the use of ROA in the OI field in order to encourage firms to undertake this innovation mode…

A real options based model to select a balanced R&D portfolio

2011

The R&D process in the pharmaceutical industry has a long and dynamic life then it is an ideal field of application for ROA. Actually, ROA implementation, as widely demonstrated in literature, is narrowed to very limited cases because its perceived complexity. This research wants to suggest a simplified method, respect the ones available in literature, that could foster the use of ROA: we built up an integer linear programming model, based on a model available in literature, useful for selecting a balanced R&D portfolio from a set of candidate drugs. The model has been tested through a case study.

An affordable way to implement real options to select optimal R&D portfolio

2011

Real option Analysis (ROA) is acknowledged as a powerful tool to evaluate uncertain projects whose uncertainty depends heavily on alternatives available along the project life. The R&D process in the pharmaceutical industry has a long and dynamic life then it is an ideal field of application for ROA. Actually, ROA implementation, as widely demonstrated in literature, is narrowed to very limited cases because its perceived complexity. This research wants to suggest a simplified method, respect the ones available in literature, that could foster the use of ROA: we built up an integer linear programming model, based on a model available in literature, useful for selecting the optimal R&D produ…

A real options based support system to open innovation

2012

Pharmaceutical R&D process (PR&DP) has been deeply investigated by different streams of literature; the interest is due to the strategic implication of the related decisions undertaken. The PR&DP has been revolutionised by the biotech advent and as a consequence R&D managers cannot avoid to consider Open Innovation paradigm during this decision process. Starting from a Real Option optimization model available in literature, the paper aims at proposing a decision support system (DSS) able to suggest the candidate products to be included in the best R&D portfolio varying input parameters (resilient products), to provide a products Pareto analysis that aims at individuating the products for wh…

EVALUATING R&D ALLIANCES UNDER UNCERTAINTY: A REAL OPTIONS APPROACH

BIOPHARMACEUTICAL ALLIANCES AND COMPETITION: A REAL OPTIONS GAMES APPROACH

2013

The competitive landscape where pharmaceutical and biotechnology companies operate has changed radically due to a scientific/technological progress that has revolutionised the process by which drugs are developed. In fact, pharmaceutical industry more and more relies on advances in biochemistry and molecular biology. As a consequence, the number of partnerships between pharmaceutical and biotech firms has grown significantly. Research contributions addressing the biopharmaceutical alliances design have also focused on the optimal timing to sign a partnership. In this paper, we introduce and analyse the effect of competition in biotechnology industry by modelling the decisions of whether and…

R&D ALLIANCE TIMING IN THE BIOPHARMACEUTICAL INDUSTRY: A REAL OPTIONS GAME APPROACH.

Real options analysis as a tool for start-up company investment valuation

2015

Pro Gradu -tutkielman tavoitteena oli tutkia Real Option Analysis -metodin sopivuutta start-up yhtiön investoinnin arvonmääritykseen. Jotta tutkimuskysymykseen saatiin vastaus, tuli myös case-yhtiön liiketoimintasuunnitelma selvittää ja edelleen mitkä ovat liiketoiminnan potentiaaliset rahavirrat, joihin arvonmääritys perustuu. Tutkimusmenetelmä oli kvantitatiivinen case-tutkimus ja tutkimusmetodi oli konstruktiivinen ja deskriptiivinen. Tutkimuksessa konstruoitiin työkalu ja arvonmääritys case-yrityksen suunnitellulle investoinnille. Toisaalta tutkimuksessa kuvailtiin arvonmääritystä yleisesti sekä Real Options Analysis -metodia. Tutkimuksen pohjaksi tutustuttiin start-up yhtiöihin, arvonm…