Search results for "Real"

showing 10 items of 4449 documents

Effects of anti-miR-182 on TSP-1 expression in human colon cancer cells: there is a sense in antisense?

2013

Abstract: Objective: miRNAs are attractive molecules for cancer treatment, including colon rectal cancer (CRC). We investigate on the molecular mechanism by which miR-182 could regulate thrombospondin-1 (TSP-1) expression, a protein down-regulated in CRC and inversely correlated with tumor vascularity and metastasis. Background: MicroRNAs are small non-coding RNAs that regulate the expression of different genes, involved in cancer progression, angiogenesis and metastasis. miR-182, over-expressed in colorectal cancer (CRC), has like predictive target thrombospondin-1 (TSP-1), a protein inversely correlated with tumor vascularity and metastasis that results downregulated in different types of…

endocrine systemPathologymedicine.medical_specialtyColorectal cancerAngiogenesisSettore MED/06 - Oncologia MedicaClinical BiochemistryEnzyme-Linked Immunosorbent AssayBiologyReal-Time Polymerase Chain ReactionMetastasisThrombospondin 1immune system diseasesCell Line TumorDrug DiscoverymicroRNAThrombospondin 1Sense (molecular biology)medicineHumansPromoter Regions GeneticDNA PrimersPharmacologyBase SequencePharmacology. Therapyvirus diseasesCancerTransfectionOligonucleotides Antisensemedicine.diseaseMicroRNAsCancer researchanti-miR-182 colon cancer Egr-1 Sp-1 thrombospondin-1Molecular MedicineColorectal Neoplasms
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Recovery of Historically Contaminated Watercourse Polluted by the Chemical Wood Industry: EROD Activity in Fish as Biomarker

2013

Despite outstanding process alterations over decades, pulp- and paper-mill-contaminated sediments and continuing exposure by the effluents may still have effects on biota. In this study, ecotoxicological impacts in the boreal watercourse were analyzed by measuring ethoxyresorufin-O-deethylase (EROD) induction from wild fish populations and from experimentally exposed fish. In order to assess the role of sediment-borne chemicals, juvenile rainbow trout (Oncorhynchus mykiss) were exposed in the laboratory to the surface sediments of Lake Vatianjarvi and Southern Lake Saimaa, both watercourses impacted by the chemical wood industry for approximately a century. Hepatic EROD activity was also me…

endocrine systemPerchanimal structuresbiologyurogenital systemanimal diseasesHealth Toxicology and MutagenesisSoil ScienceSedimentBiotabiology.organism_classificationPollutionFisheryBorealEnvironmental ChemistryEnvironmental scienceJuvenileRainbow troutRutilusEffluentSoil and Sediment Contamination: An International Journal
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Vulvar involvement in pediatric Crohn’s disease: a systematic review

2018

Purpose: The aim of the study is to report a systematic review (from 2000 to 2017) of all pediatric cases of vulvar Crohn’s disease (VCD) and to highlight the key-points for a correct diagnosis and management of this rare condition. Methods: An electronic search using the Pubmed/Medline, Scopus, EMBASE, Cochrane database and Google Scholar database was performed according to PRISMA guidelines. Results: Twenty pediatric studies and 22 cases of VCD were included for analysis. All the articles reported a single case, except two articles where two cases, respectively, are described. Clinical vulvar examination showed the following main manifestations: vulvar erythema (9/22 cases, 40.9%), vulv…

endocrine systemmedicine.medical_specialtyPediatric Crohn's diseaseVulvar edemaAdministration TopicalAdministration OralDiseasePerineumGastroenterologyVulvaPediatric Crohn’s disease030207 dermatology & venereal diseases03 medical and health sciencesPediatric Crohn’s disease0302 clinical medicineCrohn DiseaseObstetrics and gynaecologyMetronidazoleInternal medicineEdemaHumansMedicineVulvar diseaseChildbusiness.industryObstetrics and GynecologyGeneral MedicineDermatologyExtra-intestinal Crohn’s disease030220 oncology & carcinogenesisVulvar edemaFemaleVulvar DiseasesExtra-intestinal Crohn’s diseasebusinessExtra-intestinal Crohn’s disease; Pediatric Crohn’s disease; Vulvar disease; Vulvar edema; Obstetrics and Gynecology
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Acute selective ablation of rat insulin promoter-expressing (RIP HER ) neurons defines their orexigenic nature

2012

Rat insulin promoter (RIP)-expressing neurons in the hypothalamus control body weight and energy homeostasis. However, genetic approaches to study the role of these neurons have been limited by the fact that RIP expression is predominantly found in pancreatic β-cells, which impedes selective targeting of neurons. To define the function of hypothalamic RIP-expressing neurons, we set out to acutely and selectively eliminate them via diphtheria toxin-mediated ablation. Therefore, the diphtheria toxin receptor transgene was specifically expressed upon RIP-specific Cre recombination using a RIP-Cre line first described by Herrera (RIP HER -Cre) [Herrera PL (2000) Development 127:2317–2322]. Usi…

endocrine systemmedicine.medical_specialtyPituitary glandBiologyReal-Time Polymerase Chain ReactionEnergy homeostasisMiceArcuate nucleusOrexigenicInternal medicineWeight LossmedicineAnimalsInsulinPromoter Regions GeneticDorsomedial hypothalamic nucleusNeuronsDiphtheria toxinMultidisciplinarydigestive oral and skin physiologyArcuate Nucleus of HypothalamusFeeding BehaviorBiological SciencesGlucose Tolerance TestRatsEndocrinologymedicine.anatomical_structurenervous systemHypothalamusNucleushormones hormone substitutes and hormone antagonistsParaventricular Hypothalamic Nucleusmedicine.drugProceedings of the National Academy of Sciences
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Ilmasto muuttuu - energiakentän rakenne ei : tutkimus maatilojen energiaresurssien käyttöönoton ja maatilamittakaavaisen energiantuotannon rakenteell…

2005

energiavaratdemiregulariteettimaatilatkriittinen realismimikro-CHPkausaliteettibiopolttoaineet
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Impianti di produzione di energie rinnovabili: rivisitazione di categorie civilistiche

2013

energie rinnovabilitipicità dei diritti realiSettore IUS/01 - Diritto Privatoservitù
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Speed detection of battery-free nodes based on RF Wireless Power Transfer

2020

In the Internet of Things (IoT) era, Wireless Sensor Networks (WSNs) are rapidly increasing in terms of relevance and pervasiveness thanks to their notable real-time monitoring performance across several fields, including industrial, domestic, military, biomedical, commercial, environmental, and other sectors. A highly attractive implementation of WSNs is asset tracking with accurate data regarding the location and transportation conditions of goods, equipment, and the like. One highly promising application of WSNs along these lines is the remote speed monitoring of goods, ideally with battery-free sensor nodes that do not require any maintenance. This, however, represents a major challenge…

energy harvestingwsnsAsset trackingComputer scienceNode (networking)System of measurementReal-time computingwireless power transferSettore ING-IND/32 - Convertitori Macchine E Azionamenti Elettriciradio frequencySettore ING-INF/01 - Elettronicainternet of thingsPower (physics)WSNs Radio Frequency Energy Harvesting Wireless Battery Charger Lithium Ion Battery Wireless Sensor Networks Internet of ThingsbatteryWireless power transferRadio frequencylithium ionwireless sensor networksEnergy harvestingWireless sensor networkwireless battery charger
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Generalization Capacity Analysis of Non- Intrusive Load Monitoring using Deep Learning

2020

Appliance Load Monitoring is a technique used to monitor devices existing in homes, industry or naval vessels. Acquisition of device-level data can provide great benefits in many areas such as energy management, demand response, and load forecasting. However, the monitoring process is often provided with a costly installation, as it requires a large number of sensors and a data center. Non-Intrusive Load Monitoring (NILM) is an alternative and cost-efficient load monitoring solution. Simply put, NILM is the process of obtaining device-level data by analyzing the aggregated data read from the main meter that measures the electricity consumption of the whole house. Before NILM analysis is per…

energy managementComputer scienceEnergy managementbusiness.industryDeep learningReal-time computingenergy disaggregationProcess (computing)deep learningload monitoringDemand responsedemand responseMetreData centerMicrogridElectricityArtificial intelligencebusiness
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Percepción del alumnado de Educación Secundaria sobre la mediación escolar en Castellón y Valencia

2016

La realidad social, en constante proceso de cambio, exige al sistema educativo un esfuerzo por actualizar las respuestas educativas frente a la mejora de la convivencia. Es en este contexto en el que la mediación ha dejado ver sus potencialidades educativas, ya que influye sobre la mejora del individuo, de las relaciones interpersonales y del clima escolar. No obstante, son escasas las investigaciones orientadas a conocer el impacto de la misma. En este artículo presentamos un estudio dirigido a conocer la valoración de la mediación atendiendo a las opiniones del alumnado de cinco centros educativos de secundaria de Valencia y cuatro de Castellón. Asimismo, se pretende detectar si existen d…

enseñanza secundariaSchool climateSocial realitymedia_common.quotation_subjectrelaciones interpersonalesDemocratic citizenshipValència (Espanya)050109 social psychologyContext (language use)EducationInterpersonal relationshipConvivència escolarPerceptionPedagogy0501 psychology and cognitive sciencessolución de conflictosmedia_common05 social sciences050301 educationEducació SecundàriaMediació escolarevaluaciónorientaciónMediationPsychology0503 educationCastelló (Espanya)Educational systems
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A Diffractive Reading

2023

AbstractTowards the end of the editing process, we started to see the book as something more than a collection of chapters around a theme: as an assemblage, which included, of course, the community of authors. When we put out the first call for contributions in May 2018, most authors volunteered a contribution rather quickly, others joined a bit later, and some dropped out for different reasons, underlining the dynamic nature of our assemblage. In pre-pandemic times, we met on and off campus, introduced some of our ideas at conferences, and had a workshop day to brainstorm, plan chapters, and reflect on the process and the purpose of the book. We were connected by common meals, jokes, writi…

entangled ethicsagential realismyhteisöllisyyskokoomateoksetdiffractiontoimitustyöontologia (filosofia)yhteistyödiffraktiorelationalitysosiomateriaalisuusuusmaterialismitutkimusontological variationetiikkakirjoittaminen
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