Search results for "Rectal"

A Shape-based Statistical Method to Retrieve 2D TRUS-MR Slice Correspondence for Prostate Biopsy

2012

International audience; This paper presents a method based on shape-context and statistical measures to match interventional 2D Trans Rectal Ultrasound (TRUS) slice during prostate biopsy to a 2D Magnetic Resonance (MR) slice of a pre-acquired prostate volume. Accurate biopsy tissue sampling requires translation of the MR slice information on the TRUS guided biopsy slice. However, this translation or fusion requires the knowledge of the spatial position of the TRUS slice and this is only possible with the use of an electro-magnetic (EM) tracker attached to the TRUS probe. Since, the use of EM tracker is not common in clinical practice and 3D TRUS is not used during biopsy, we propose to per…

Effects of ectopic expression of NGAL on doxorubicin sensitivity.

2012

Neutrophil gelatinase-associated lipocalin (NGAL, a.k.a Lnc2) is a member of the lipocalin family which has diverse roles including stabilizing matrix metalloproteinase-9 from auto-degradation and as siderocalins which are important in the transport of iron. NGAL also has important biological functions involved in immunity and inflammation as well as responses to kidney damage. NGAL expression has also been associated with certain neoplasia and is important in the metastasis of breast cancer. Many advanced cancer patients have elevated levels of NGAL in their urine and it has been proposed that NGAL may be a prognostic indicator for certain cancers (e.g. breast, brain, and others). NGAL exp…

Relación del margen de resección con la supervivencia global y supervivencia libre de enfermedad de los pacientes afectos de metástasis hepáticas de …

2015

Actualmente, la resección hepática junto con la quimioterapia representa el único tratamiento curativo para las metástasis hepáticas de carcinoma colorrectal (MHCCR), con unas tasas de supervivencia a 5 años de hasta el 58%.1 Los últimos avances en supervivencia se deben a múltiples factores.2 Por una parte, a las nuevas estrategias quirúrgicas (embolización portal preoperatoria, hepatectomía en dos tiempos, etc); así como a la mejor selección de pacientes candidatos a cirugía en base a las nuevas definiciones de resecabilidad.3-5 Y por supuesto, al desarrollo de una quimioterapia más efectiva y de nuevos agentes biológicos para el tratamiento de los pacientes con MHCCR.6-10 El papel del ma…

Advanced Management Protocol of Transanal Irrigation in Order to Improve the Outcome of Pediatric Patients with Fecal Incontinence

2021

Background: Transanal irrigation (TAI) is employed for children with fecal incontinence, but it can present several problems which require a study of their outcomes among different pathologies and without a tailored work up. The aim of our study was to evaluate the effectiveness of an advanced protocol in order to tailor TAI, prevent complications, and evaluate outcomes. Methods: We included 70 patients (14 anorectal malformation, 12 Hirschsprung’s disease, 24 neurological impairment, 20 functional incontinence) submitted to a comprehensive protocol with Peristeen®: fecal score, volumetric enema, rectal ultrasound, anorectal 3D manometry, and diary for testing and parameter adjustment. Resu…

Tumor-derived exosomes as factors that promote metastatic niche formation: evaluation of the effects induced by colon cancer derived exosomes on func…

2023

Urīnizvadceļu agrīno komplikāciju raksturojums pacientiem pēc taisnās zarnas vēža rezekcijas

2018

Mūsdienu klīniskajā medicīnā taisnās zarnas vēzis ir viena no nopietnām problēmām. Taisnās zarnas vēža ārstēšana balstās, galvenokārt, uz ķirurģiskās operācijas, kas, neskatoties uz visu mūsdienas medicīnas attīstību, var novest pie vairākām komplikācijām. Starp visiem pēcoperācijas traucējumiem vienu no vietām aizņem urīna izvadceļu komplikācijas. Zinātniskajos avotos ir aprakstīts, ka pētāmā problēma ir sastopamā 5-88% gadījumos, vīdēji 27% gadījumos, kas ir ļoti būtiski. Minētā tēma ir pētīta no pagājušā gadsimta, bet neskatoties uz lielu un aktīvo zinātnisko interesi, arī šodien pastāv dažādi un dažreiz pretrunīgi viedokļi un atšķirīgi dati par faktoriem, kas ietekmē pēcoperācijas urīna…

Factores de riesgo de infección de la herida quirúrgica en cirugía electiva de cáncer de sigma y recto. Implantación de un programa de vigilancia

2014

Objetivos: Conocer la tasa de infección de la herida quirúrgica (SSI), laparotómica y perineal, en cirugía oncológica electiva colorrectal y determinar sus respectivos factores de riesgo independientes. Expresar el riesgo o probabilidad de sufrir dicha infección, a través de la incidencia acumulada (IA) y la densidad de incidencia (DI). Evaluar las diferencias entre la cirugía preservadora de esfínteres (CPE) y la amputación abdominoperineal (AAP) en cuanto a la infección de la laparotomía en el cáncer de recto. Conocer la morbilidad no infecciosa de la herida perineal tras AAP y sus factores de riesgo. Valorar el efecto de medidas correctoras aplicadas en el tiempo para disminuir la SSI y …

Predominance of Type 1 Innate Lymphoid Cells in the Rectal Mucosa of Patients With Non-Celiac Wheat Sensitivity: Reversal After a Wheat-Free Diet.

2016

OBJECTIVES: Non-celiac wheat sensitivity (NCWS) is defined as a reaction to ingested wheat after exclusion of celiac disease and wheat allergy. As its pathogenesis is incompletely understood, we evaluated the inflammatory response in the rectal mucosa of patients with well-defined NCWS. METHODS: The prospective study included 22 patients with irritable bowel syndrome (IBS)-like clinical presentation, diagnosed with NCWS by double-blind placebo-controlled challenge. Eight IBS patients not improving on wheat-free diet were used as controls. Two weeks after oral challenge was performed with 80 grams of wheat daily, cells were isolated from rectal biopsies and thoroughly characterized by fluore…