Search results for "Reduct"

showing 10 items of 2879 documents

Diode laser welding of ABS: Experiments and process modeling

2009

International audience; The laser beam weldability of acrylonitrile/butadiene/styrene (ABS) plates is determined by combining both experimental and theoretical aspects. In modeling the process, an optical model is used to determine how the laser beam is attenuated by the first material and to obtain the laser beam profile at the interface. Using this information as the input data to a thermal model, the evolution of the temperature field within the two components can be estimated. The thermal model is based on the first principles of heat transfer and utilizes the temperature variation laws of material properties. Corroborating the numerical results with the experimental results, some impor…

0209 industrial biotechnologyProcess modelingMaterials scienceWeldabilityMechanical engineeringFOS: Physical sciences02 engineering and technologySemiconductor laser theory020901 industrial engineering & automationOptics[ PHYS.MECA.THER ] Physics [physics]/Mechanics [physics]/Thermics [physics.class-ph]Semitransparent polymersElectrical and Electronic EngineeringDiodebusiness.industryACLLaser beam welding[CHIM.MATE]Chemical Sciences/Material chemistry021001 nanoscience & nanotechnology[ SPI.MECA.THER ] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Thermics [physics.class-ph]Atomic and Molecular Physics and OpticsExperimental designElectronic Optical and Magnetic Materials[ CHIM.MATE ] Chemical Sciences/Material chemistryHeat transfer[PHYS.MECA.THER]Physics [physics]/Mechanics [physics]/Thermics [physics.class-ph][SPI.MECA.THER]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Thermics [physics.class-ph]Laser welding0210 nano-technologyReduction (mathematics)Material propertiesbusinessPhysics - OpticsOptics (physics.optics)
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A note on best proximity point theory using proximal contractions

2018

In this paper, a reduction technique is used to show that some recent results on the existence of best proximity points for various classes of proximal contractions can be concluded from the corresponding results in fixed point theory.

021103 operations researchApplied MathematicsMathematical analysisBest proximity point0211 other engineering and technologiesproximal contractionfood and beveragesFixed-point theorem02 engineering and technologyFixed point01 natural sciencesPoint theory010101 applied mathematicsProximal contractionReduction (complexity)fixed pointModeling and SimulationGeometry and Topology0101 mathematicsMathematics
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Climate Change and Disasters

2017

Ideas and approaches proven successful within disaster risk reduction (DRR) literature and practice are either bypassed or inadequately considered by contemporary climate change work. This chapter explores the intersections between climate change and hazards, vulnerability, and risk, looking at climate change as both a hazard driver and a hazard inhibitor. The implications of the narrow interpretations of vulnerability employed in climate change work are examined, as well as the ways in which climate change has come to act as a scapegoat for issues, events, and processes caused by hazard-independent factors. The chapter formulates a case for climate change adaptation (CCA) to be seen as a s…

021110 strategic defence & security studies010504 meteorology & atmospheric sciencesDisaster risk reduction0211 other engineering and technologiesVulnerabilityClimate change02 engineering and technology01 natural sciencesHazardClimate change mitigationWork (electrical)Political scienceSustainabilityClimate change adaptationEnvironmental planning0105 earth and related environmental sciences
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The impact on disaster governance of the intersection of environmental hazards, border conflict and disaster responses in Ladakh, India

2018

Abstract The Indian border region of Ladakh, in Jammu and Kashmir State, has a sensitive Himalayan ecosystem and has experienced natural hazards and disasters of varying scales over the decades. Ladakh is also situated on a fault-line of multiple tensions, including ongoing border disagreements and intermittent conflict with China and Pakistan. The Indian army has thus become a permanent fixture in the region. This paper examines the implications of the intersection of these environmental and security factors for disaster governance in the region. Using Social Domains theory, the paper argues first, that a hazard-centred paradigm of ‘universal’ disaster science emerges from the colonial per…

021110 strategic defence & security studiesCivil societyeducation.field_of_studyNational security010504 meteorology & atmospheric sciencesDisaster risk reductionEmergency managementbusiness.industryCorporate governancePopulation0211 other engineering and technologiesPoison controlGeology02 engineering and technologyBuilding and ConstructionGeotechnical Engineering and Engineering Geology01 natural sciencesEconomyPolitical scienceNatural hazardbusinesseducationSafety Research0105 earth and related environmental sciencesInternational Journal of Disaster Risk Reduction
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Connecting theories of cascading disasters and disaster diplomacy

2018

Abstract Disaster diplomacy examines how and why disaster-related activities (disaster risk reduction and post-disaster actions) do and do not influence peace and conflict processes, especially whether or not a causal chain can be established between dealing with disaster risk or a disaster and outcomes in peace or conflict. Cascading disasters might provide a useful theoretical framing for mapping out causal pathways for disaster diplomacy. In conceptually exploring the intersection between disaster diplomacy and cascading disasters, this paper concludes that both disaster diplomacy and cascading disasters have limitations because they try to develop focused causal chains which, when exami…

021110 strategic defence & security studiesDisaster risk reductionmedia_common.quotation_subject05 social sciences0211 other engineering and technologiesGeology02 engineering and technologyGeotechnical Engineering and Engineering Geology0506 political scienceFraming (social sciences)Political economyPolitical science050602 political science & public administrationCausal chainSafety ResearchDiplomacyCausal pathwaysmedia_commonInternational Journal of Disaster Risk Reduction
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The role of social perception in disaster risk reduction: Beliefs, perception, and attitudes regarding flood disasters in communities along the Volta…

2017

Abstract People's perceptions of natural, spiritual, and social phenomena are socially constructed. Social perception is important because it helps people to make sense of the physical and social world and therein interact with it. Earlier research specializing in the study of human behaviour has emphasized a linkage between people's perceptions and their behaviour. In this article, the authors employ a similar theory with the intent of proposing a theoretical framework that examines the factors that influence people's perception and attitude (mitigation and response) towards the hazards they face. This discussion is done on the premise of “culture”, “experiences” and “disaster risk reducti…

021110 strategic defence & security studiesGovernment010504 meteorology & atmospheric sciencesEmergency managementDisaster risk reductionSocial perceptionbusiness.industrymedia_common.quotation_subject0211 other engineering and technologiesGeology02 engineering and technologyPublic relationsGeotechnical Engineering and Engineering GeologySocial constructionism01 natural sciencesAgency (sociology)InstitutionPsychologybusinessSafety ResearchSocial psychology0105 earth and related environmental sciencesmedia_commonQualitative researchInternational Journal of Disaster Risk Reduction
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Helices of disaster memory: How forgetting and remembering influence tropical cyclone response in Mauritius

2020

Abstract Tropical cyclones have had a considerable impact on Mauritius. Large cyclones are relatively rare, and in popular imagination are thought to hit Mauritius every 15 years. Yet it has been over 25 years since the last cyclone widely considered as ‘significant’. Critically, there is little known about the role of memory in responses to cyclones and details regarding responses to past cyclones in Mauritian history are scant. This article examines past experiences and impacts of cyclones in Mauritius, as well as contemporary perceptions of cyclone vulnerability and memories of historical cyclones. The analysis draws on both community interviews and archival research conducted in Mauriti…

021110 strategic defence & security studiesHistoryForgetting010504 meteorology & atmospheric sciencesDisaster risk reductionmedia_common.quotation_subject0211 other engineering and technologiesVulnerabilityGeology02 engineering and technologyBuilding and ConstructionGeotechnical Engineering and Engineering Geology01 natural sciencesArchival researchPerceptionCycloneEconomic geographyClimate change adaptationTropical cycloneSafety Research0105 earth and related environmental sciencesmedia_commonInternational Journal of Disaster Risk Reduction
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2,3-Dihydrobenzofuran privileged structures as new bioinspired lead compounds for the design of mPGES-1 inhibitors

2016

International audience; 2,3-Dihydrobenzofurans are proposed as privileged structures and used as chemical platform to design small compound libraries. By combining molecular docking calculations and experimental verification of biochemical interference, we selected some potential inhibitors of microsomal prostaglandin E2 synthase (mPGES)-1. Starting from low affinity natural product 1, by our combined approach we identified the compounds 19 and 20 with biological activity in the low micromolar range. Our data suggest that the 2,3-dihydrobenzofuran derivatives might be suitable bioinspired lead compounds for development of new generation mPGES-1 inhibitors with increased affinity.

0301 basic medicine300323-Dihydrobenzofuran privileged structure; Cancer; Inflammation; Molecular docking; mPGES-1 inhibitors; Biochemistry; Clinical Biochemistry; Molecular Biology; Molecular Medicine; Organic Chemistry; Drug Discovery3003 Pharmaceutical Science; 3003Amino Acid MotifsClinical BiochemistryGene ExpressionPharmaceutical Science01 natural sciencesClinical biochemistryBiochemistry[ CHIM ] Chemical SciencesProtein Structure Secondary[ SDV.CAN ] Life Sciences [q-bio]/Cancerchemistry.chemical_compoundLow affinityDrug DiscoveryEnzyme Inhibitors23-Dihydrobenzofuran privileged structure; Molecular docking; mPGES-1 inhibitors; Cancer; InflammationProstaglandin-E SynthasesCancerAnti-Inflammatory Agents Non-SteroidalBiological activityProto-Oncogene Proteins c-metIntramolecular OxidoreductasesMolecular Docking SimulationMolecular dockingMolecular Medicinelipids (amino acids peptides and proteins)Cell SurvivalStereochemistryMolecular Sequence Data2Antineoplastic Agents[SDV.CAN]Life Sciences [q-bio]/Cancer3-Dihydrobenzofuran privileged structureInhibitory Concentration 50Structure-Activity Relationship03 medical and health sciencesCell Line TumorMicrosomesHumans[CHIM]Chemical SciencesMolecular BiologyBenzofuransInflammationNatural product010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceOrganic ChemistryEpithelial CellsmPGES-1 inhibitorsCombinatorial chemistryCombined approach0104 chemical sciences030104 developmental biologychemistryDrug DesignDrug Screening Assays Antitumor
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Unity Makes Strength: A Review on Mutualistic Symbiosis in Representative Insect Clades

2019

Settled on the foundations laid by zoologists and embryologists more than a century ago, the study of symbiosis between prokaryotes and eukaryotes is an expanding field. In this review, we present several models of insect–bacteria symbioses that allow for the detangling of most known features of this distinctive way of living, using a combination of very diverse screening approaches, including molecular, microscopic, and genomic techniques. With the increasing the amount of endosymbiotic bacteria genomes available, it has been possible to develop evolutionary models explaining the changes undergone by these bacteria in their adaptation to the intracellular host environment. The establishmen…

0301 basic medicine<i>Buchnera</i>Sulcia030106 microbiologyPopulationminimal genomesSymbiotic replacementconsortium<i>Tremblaya</i>Reviewsymbiotic replacementPrimary endosymbiontGenomeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesMinimal genomesBuchneraSymbiosisgenome-reduction syndromelcsh:ScienceCladeeducationEcology Evolution Behavior and Systematicseducation.field_of_studyendosymbiosisEndosymbiosisEndosymbiosisbiologyHost (biology)secondary endosymbiontPaleontologyprimary endosymbiontTremblayaGenome-reduction syndromebiology.organism_classificationSecondary endosymbiont030104 developmental biology<i>Sulcia</i>Space and Planetary ScienceEvolutionary biologylcsh:QAdaptationBuchneraConsortiumLife
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New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease

2019

The Global Burden of Disease Study identified cardiovascular risk factors as leading causes of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism that is associated with most of these risk factors and stressors, and represents an early (subclinical) marker/predictor of atherosclerosis. Oxidative stress is a trigger of endothelial dysfunction and it is a hall-mark of cardiovascular diseases and of the risk factors/stressors that are responsible for their initiation. Endothelial function is largely based on endothelial nitric oxide synthase (eNOS) function and activity. Likewise, oxidative stress can lead to the loss of eNOS activity or even &ldquo;uncoupli…

0301 basic medicineAdipose tissueReview030204 cardiovascular system & hematologyPharmacologymedicine.disease_causeendothelial dysfunctionEpigenesis Geneticlcsh:Chemistry0302 clinical medicineEnoscardiovascular diseaseeNOS uncouplingoxidative stressEndothelial dysfunctionlcsh:QH301-705.5Spectroscopyenvironmental stressorsbiologyGeneral MedicineComputer Science Applicationsmedicine.anatomical_structureCardiovascular Diseasesmedicine.symptomOxidation-ReductionCell signalingEndotheliumNitric Oxide Synthase Type IIIInflammationModels BiologicalCatalysisInorganic Chemistry03 medical and health scienceslife style/behavioral health risk factorsmedicineAnimalsHumansPhysical and Theoretical ChemistryMolecular Biologybusiness.industryOrganic Chemistrymedicine.diseasebiology.organism_classification030104 developmental biologylcsh:Biology (General)lcsh:QD1-999Socioeconomic FactorsinflammationSoluble guanylyl cyclasebusinessOxidative stressInternational Journal of Molecular Sciences
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