Search results for "Reference value"

showing 10 items of 536 documents

Distribution and categorization of left ventricular measurements in the general population: results from the population-based Gutenberg Heart Study.

2010

Background— Echocardiography, the dominant imaging modality for quantification of left ventricular metrics, has undergone continuing development in the past few decades. However, given the lack of population-based data, current guidelines are still based on restricted and small data sets analyzed with methods including expert opinion. This work presents empirically derived reference values from a large-scale, epidemiologic study conducted with state-of-the-art imaging technology and methods. Methods and Results— The distribution of echocardiographic measurements of the left ventricle was analyzed in a population-based sample of 5000 mid-Europeans from the Gutenberg Heart Study in Germany. …

AdultMalemedicine.medical_specialtyHeart DiseasesHeart VentriclesPopulationSample (statistics)Severity of Illness IndexVentricular Function LeftAge DistributionSex FactorsPredictive Value of TestsReference ValuesGermanyMedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesSex DistributioneducationAgedUltrasonographyAged 80 and overeducation.field_of_studybusiness.industryAge FactorsNomogramMiddle AgedHealth SurveysQuantile regressionSurgeryData setNomogramsCategorizationPredictive value of testsImaging technologyFemaleCardiology and Cardiovascular MedicinebusinessCartographyCirculation. Cardiovascular imaging
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Alterations in androgen conjugate levels in women and men with alopecia.

1994

Objective To assess levels of androgen metabolites thought to reflect, at least in part, peripheral androgen activity in women with androgenic alopecia and men with premature balding in an effort to determine if a common abnormality exists. Design Prospective study in various groups of women and men. Setting Reproductive Endocrine Clinic at our university medical center. Patients Ten normal ovulatory female controls and 50 hyperandrogenic women divided on the basis of hirsutism and alopecia as follows: [1] 8 hirsute women with androgenic alopecia; [2] 12 nonhirsute women with androgenic alopecia; [3] 18 hirsute women without androgenic alopecia; and [4] 12 nonhirsute women without androgeni…

AdultMalemedicine.medical_specialtyHirsutismAndrosterone glucuronideAdolescentmedicine.drug_classReference ValuesInternal medicinemedicineEndocrine systemHumansAndrostenedioneProspective StudieshirsutismSex Characteristicsbusiness.industryHyperandrogenismObstetrics and GynecologyAlopeciamedicine.diseaseAndrogenAndrosterone SulfateEndocrinologyReproductive MedicineAndrogensFemaleGlucuronidebusinessHyperandrogenismFertility and sterility
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Hormonal Responses of Multiset Versus Single-Set Heavy-Resistance Exercise Protocols

1997

The purpose of this study was to compare serum growth hormone (GH), testosterone (T), cortisol (C) and whole blood lactate (L) responses to single set (1S) versus multiple set (3S) heavy-resistance exercise protocols. Eight recreationally weight-trained men completed two identical resistance exercise workouts (1S vs. 3S). Blood was obtained prexcerise (PRE), immediately postexercise (0P), and 5 min (5P), 15 min (15P), 30 min and 60 min (60P) postexercise and was analyzed for GH, T, C, and L levels. For 1S and 3S, GH, L, and T significantly increased from PRE to 0P and remained significantly elevated to 60P, except for 1S. For GH, T, and L, 3S showed significantly greater increases compared…

AdultMalemedicine.medical_specialtyHydrocortisonePhysiologymedicine.drug_classRadioimmunoassayPhysical exerciseBiologyReference ValuesInternal medicinemedicineHumansTestosteroneOrthopedics and Sports MedicineLactic AcidExercise physiologyExerciseTestosteroneWhole bloodHydrocortisoneCross-Over StudiesExercise ToleranceAndrogenEndocrinologyGrowth HormoneGlucocorticoidmedicine.drugHormoneCanadian Journal of Applied Physiology
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Technical note: a comparison of central and peripheral intraocular pressure using rebound tonometry

2007

Purpose: To compare central and peripheral intraocular pressure (IOP) readings obtained with rebound tonometry.Methods: Intraocular pressure was measured on the right eye of 153 patients (65 males, 88 females), aged from 21 to 85 years (mean +/- S.D., 55.5 +/- 15.2 years) with the ICare rebound tonometer at centre, and 2 mm from the limbus (in the nasal and temporal regions along the 0-180O corneal meridian).Results: Intraocular pressure values obtained with the ICare were 14.9 +/- 2.8; 14.1 +/- 2.5 and 14.5 +/- 2.7 mmHg at centre, nasal and temporal corneal locations, respectively. On average, nasal and temporal IOP readings were 0.75 and 0.37 mmHg lower than the central reading (p 0.05, r…

AdultMalemedicine.medical_specialtyIntraocular pressuregenetic structuresSensitivity and SpecificityICare((R))Cornea03 medical and health sciencesTonometry Ocular0302 clinical medicineReference ValuesOphthalmologyCorneamedicineHumansIntraocular PressureAgedAged 80 and overScience & Technologybusiness.industryReproducibility of ResultsTechnical noteREBOUND TONOMETRYMiddle AgedSensory Systemseye diseasesPeripheralOphthalmologymedicine.anatomical_structureMeridian (perimetry visual field)Temporal RegionsReference values030221 ophthalmology & optometryFemalerebound tonometrysense organsICare®corneal structureperipheral tonometrybusiness030217 neurology & neurosurgeryOptometryintraocular pressure
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Normal reference values of multilayer longitudinal strain according to age decades in a healthy population: A single-centre experience.

2017

Aims Recent advancements in echocardiographic technology allow to analyse myocardial strain in multiple layers. Little is known about the impact of age on layer-specific longitudinal strain in healthy subjects. The aim of this study was to analyse the influence of age on multilayer longitudinal strain and establish normal reference values of layer-specific strain according to age decades in a healthy population referring to our echo laboratory using 2D speckle-tracking echocardiography with layer-specific software. Methods and results Two-hundred sixty-six healthy, consecutive subjects (mean age = 39.2 ± 17.5 years, women/men = 137/129), free of cardiovascular risk factors, were enrolled. S…

AdultMalemedicine.medical_specialtyLongitudinal strain030204 cardiovascular system & hematologyVentricular Function LeftCohort Studies03 medical and health sciences0302 clinical medicineReference ValuesInternal medicineLinear regressionImage Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imaging030212 general & internal medicineProspective StudiesProspective cohort studyObserver VariationStrain (chemistry)business.industrysubendocardial strainConfoundingsubepicardial strainAge FactorsStroke VolumeGeneral MedicineMiddle AgedHealthy VolunteersageingAgeingEchocardiographyReference valuesCardiologyLinear ModelsFemaleCardiology and Cardiovascular Medicinebusinessglobal longitudinal strainglobal longitudinal strain subepicardial strain subendocardial strain echocardiography ageingCohort studyEuropean heart journal. Cardiovascular Imaging
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3D echocardiographic reference ranges for normal left ventricular volumes and strain: results from the EACVI NORRE study

2017

International audience; Aim: To obtain the normal ranges for 3D echocardiography (3DE) measurement of left ventricular (LV) volumes, function, and strain from a large group of healthy volunteers. Methods and results: A total of 440 (mean age: 45 ± 13 years) out of the 734 healthy subjects enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study had good-quality 3DE data sets that have been analysed with a vendor-independent software package allowing homogeneous measurements regardless of the echocardiographic machine used to acquire the data sets. Upper limits of LV end-diastolic and end-systolic volumes were larger in men (97 and 42 mL/m2)…

AdultMalemedicine.medical_specialtyLongitudinal strainadult echocardiographydeformation imagingHeart VentriclesCardiac VolumeDiastoleEchocardiography Three-Dimensional030204 cardiovascular system & hematologyVentricular Function LeftHeart VentricleReference values03 medical and health sciencesYoung Adultleft ventricular function0302 clinical medicineInternal medicineHealthy volunteersthree-dimensional echocardiographyMedicineCircumferential strainHumansRadiology Nuclear Medicine and imagingReference Value030212 general & internal medicineSystoleAgedEjection fractionStrain (chemistry)business.industryGeneral MedicineMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREMiddle AgedHealthy VolunteerHealthy Volunteers3. Good healthRadiology Nuclear Medicine and imagingReference valuesCardiologyFemale[SDV.IB]Life Sciences [q-bio]/BioengineeringbusinessCardiology and Cardiovascular MedicineHuman
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The effect of acupuncture on oral microcirculation in healthy volunteers: an exploratory study.

2009

Background Acupuncture is a therapeutic technique currently used in the treatment of many pathologies. The aim of this study is to evaluate the potential effect of acupuncture on “in vivo” variations in oral microcirculation in healthy subjects. Methods An exploratory study was conducted on 40 healthy subjects: 20 cases (mean 55.90, SD 16.04) and 20 controls (mean 51, SD 11.91). Videocapillaroscopy was used to detect variations in oral microcirculation. This method permits an accurate and non-invasive in vivo study of the capillaries of the oral mucous. The site selected for this pilot study is the lower lip since it is the simplest to investigate and is more readily accessible. Assessments…

AdultMalemedicine.medical_specialtyLower lipAcupuncture TherapyPilot ProjectsStatistics NonparametricMicrocirculationacupuncture oral microcirculation03 medical and health sciences0302 clinical medicineReference ValuesSettore MED/28 - Malattie OdontostomatologicheHealthy volunteersAcupuncturemedicineHumansTherapeutic Techniquebusiness.industryHealthy subjectsMouth MucosaGeneral MedicineSimilar timeMiddle AgedLip030205 complementary & alternative medicineCapillariesComplementary and alternative medicine030220 oncology & carcinogenesisAnesthesiaPhysical therapyAfferent loopFemaleNeurology (clinical)businessAcupuncture PointsBlood Flow Velocity
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Activity of the adenylyl cyclase in lymphocytes of male alcoholic patients is state dependent.

1998

A decreased basal and/or stimulated activity of the G-protein/adenylyl cyclase (AC) system in peripheral blood cells has been proposed to represent a trait marker for alcoholism. However, AC activity may underlie state-dependent changes, which may impair a proper interpretation of AC activity measurements. Our study examined systematically the AC activity in peripheral lymphocytes of 73 male alcohol-dependent patients (according to DSM-IV criteria) at three different time points of measurement during the clinical course of detoxification (day 0 = at admission, while still ethanol-affected; day 2 = at the presumed peak of withdrawal symptoms; day E = after detoxification). Basal and stimulat…

AdultMalemedicine.medical_specialtyLymphocyteGTPgammaSMedicine (miscellaneous)ToxicologyAdenylyl cyclaseAlcohol Withdrawal Deliriumchemistry.chemical_compoundBasal (phylogenetics)Reference ValuesInternal medicineDetoxificationmedicineHumansLymphocytesAgedForskolinbusiness.industryMiddle AgedPeripheralPsychiatry and Mental healthAlcoholismmedicine.anatomical_structureEndocrinologychemistryToxicitybusinessBiomarkersAdenylyl CyclasesAlcoholism, clinical and experimental research
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Assessment of various factors influencing esophageal pressure measurement. II. Significance of physiological factors in intraluminal manometry.

1980

In the second part of this study the effect of age, sex, body size, body weight and timing of the manometric examination (morning vs. noon) on esophageal pressure measurement was investigated in a total of 119 healthy subjects, using an electromagnetic microtransducer. Additionally intraindividual variation of pressures was studied over a period of 6 months. Of these parameters only age influenced upper esophageal sphincter (UES) pressure significantly: The mean UES pressure of younger subjects (20-49 years) was significantly higher (144.4 +/- 8.6 mmHg) compared to that of older subjects (50-80 years) where a mean pressure of 103.4 +/- 7.2 mmHg was recorded (p less than 0.0005). Intraindivi…

AdultMalemedicine.medical_specialtyManometryNormal valuesBody weightEsophagusSex FactorsReference ValuesInternal medicineDrug DiscoverymedicineHumansCircadian rhythmEsophagusGenetics (clinical)MorningPeristalsisAgedbusiness.industryBody WeightAge FactorsGeneral MedicineMiddle AgedCircadian Rhythmmedicine.anatomical_structureCardiologyEsophageal sphincterMolecular MedicineEsophageal pressureFemalePeristalsisbusinessKlinische Wochenschrift
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Circulating hematopoietic progenitor cells in runners

2002

Because endurance exercise causes release of mediators and growth factors active on the bone marrow, we asked whether it might affect circulating hematopoietic progenitor cells (HPCs) in amateur runners [ n = 16, age: 41.8 ± 13.5 (SD) yr, training: 93.8 ± 31.8 km/wk] compared with sedentary controls ( n = 9, age: 39.4 ± 10.2 yr). HPCs, plasma cortisol, interleukin (IL)-6, granulocyte colony-stimulating factor (G-CSF), and the growth factor fms-like tyrosine kinase-3 (flt3)-ligand were measured at rest and after a marathon (M; n = 8) or half-marathon (HM; n = 8). Circulating HPC counts (i.e., CD34+cells and their subpopulations) were three- to fourfold higher in runners than in controls at b…

AdultMalemedicine.medical_specialtyMarathonTime FactorsHydrocortisonePhysiologymedicine.medical_treatmentPhysical Therapy Sports Therapy and RehabilitationAntigens CD34Settore MED/10 - Malattie Dell'Apparato RespiratorioSettore BIO/09 - FisiologiaRunningEndocrinologyReference ValuesEndurance trainingPhysiology (medical)Internal medicineGranulocyte Colony-Stimulating FactormedicineHumansOrthopedics and Sports MedicineProgenitor cellCytokineBlood CellsPhysical Education and TrainingHematopoietic cellInterleukin-6business.industryGrowth factorMembrane ProteinsGrowth factorMiddle AgedHematopoietic Stem CellsEndurance trainingBlood Cell CountCytokinemedicine.anatomical_structureEndocrinologyembryonic structuresImmunologyPhysical EnduranceHematopoietic progenitor cellsBone marrowCytokines; Endurance training; Growth factors; Marathon; Physiology; Endocrinology; Orthopedics and Sports Medicine; Physical Therapy Sports Therapy and Rehabilitationbusinesshuman activities
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