Search results for "Reference"
showing 10 items of 2491 documents
L’acarien transporteur d’allergènes
2016
Resume Les acariens et les moisissures cohabitent dans les logements. Ils sont les principaux allergenes impliques dans l’asthme allergique. Dans les silos a grains et les archives, les acariens transportent des spores et contaminent leurs environnements. Les acariens, par leurs choix alimentaires, selectionnent certaines especes. Sous l’action de spores, la liberation de la guanine et d’acides gras favorisent l’accouplement des acariens. La competition intervient egalement entre les acariens pour la colonisation de leur habitat. Les acariens presentent des tailles et des capacites de deplacement variables et certaines especes peuvent donc s’imposer au detriment d’autres. Les conditions de …
Goût et plaisir alimentaire chez la personne âgée : des idées reçues à la réalité scientifique
2018
National audience
Xenohormones and oral homeostasis : impact on taste preferences and salivary glands
2012
Oral homeostasis strongly influences taste perceptions. It depends on a healthy oral epithelium and salivary gland secretions, which are both regulated by sex hormones. The aim of this thesis was to identify the effect of an oral exposure to Bisphenol A, a food packaging and dental sealer component, and of a soy-diet containing phytoestrogens on oral homeostasisTwo experiments were conducted in adult rats: a dose-response study of BPA (5μg 12.5 mg / kj / day), and a study about the impact of a soy-diet on the BPA disrupting effects. By using gustation choice tests, and histological and qPCR-TR molecular approach, we identify for the first time an action of BPA on dry mouth. We found that BP…
Les comportements préalables à la prise lactée chez le souriceau : caractérisation de sécrétions maternelles réactogènes et implication de l'expérien…
2012
Birth is one of the most delicate periods mammalian infants have to deal with. Newborns have then to adapt physiologically and behaviorally to the aerial environment, and one of their first challenges is to ingest colostrum and milk. It is paradoxical that the survival of pups is conditioned by the success of this first suckling, and that we have so little understanding of the stimuli that underlie and promote it. Thus, the present work aims to contribute to answer how immature and naïve newborns do manage to orient to a nipple, to grasp it, and to suckle efficiently? This general issue will be addressed in the mouse in focusing on: i) the nature of the chemical substrates that newborn mice…
The study of calcium signaling in lipid gustatory cells in mice
2012
The lipid-binding glycoprotein CD36, expressed by circumvallate papillae (CVP) of the mouse tongue, has been shown to be implicated in oro-gustatory perception of dietary lipids. We demonstrate that linoleic acid (LA) by activating sPLA2, cPLA2 and iPLA2 via CD36, produced arachidonic acid (AA) and lyso-phosphatidylcholine (Lyso-PC) which triggered Ca2+ influx in CD36-positive taste bud cells (TBC), purified from mouse CVP. LA induced the production of Ca2+ influx factor (CIF). CIF, AA and Lyso-PC exerted different actions on the opening of store-operated Ca2+ (SOC) channels, constituted of Orai proteins and regulated by STIM1, a sensor of Ca2+ depletion in the endoplasmic reticulum. We use…
Développement de méthodes de référence pour les biomarqueurs du bilan lipidique : application au contrôle qualité en biologie clinique
2013
Reliable measurements in medical biology are essential for early screening and appropriate follow-up of patients. Ensuring metrological traceability of clinical measurements to higher order reference methods or certified reference materials enables to obtain comparable results over time and between different laboratories that could use different methods to quantify the same biomarker.In this study, reference methods were developed and validated for lipid profile biomarkers (total cholesterol, triglycerides, HDL-C, and LDL-C). Their value added in proficiency testing schemes was demonstrated against consensus mean. They were also used to characterize a certified reference material (CRM) that…
Is the improvement of the nutritional quality compatible with the maintenance of the sensory quality? : the example of biscuits
2013
French biscuit producers are willing to improve the nutritional composition of their products. The. objective of this work was to determine whether it was possible while maintaining the sensory. quality of the reduced product. The first study dealt with the impact of fat and sugar reduction on liking and sensory perception of. 9 types of biscuits and cakes. Results show that children perceived almost no difference and liked. equally the standard and the fat- and/or sugar-reduced variants for most types of biscuits. For. products reduced without adding polyols, adults less like fat- or sugar-reduced variants than. standard ones mainly when they were perceived as less sweet, and to a lesser e…
Identification of sustainable cropping systems with high multi-sector performances
2014
International audience; Multicriteria assessment is needed to identify promising cropping systems with good performances on different components of sustainability. Some trade-offs between criteria may occur. A better knowledge about the relationship between criteria can help (i) to ide ntify cropping systems with high multi-sector performances (e.g. Castoldi et al., 2010; Firbank et al., 2013), and (ii) to guide policy makers’choices. In this paper, we present the early results from our multi-sector evaluation performed on data collected on cropping systems experiments.
Diversité et structuration génétique des populations de bleuets sauvages, horticoles et de jachères fleuries, à l’échelle nationale et régionale
2017
Master
S-Nitrosylation de la proteine L7A
2017
Master