Search results for "Registration"

showing 10 items of 146 documents

Disclosing progress in cancer survival with less delay

2019

Cancer registration plays a key role in monitoring the burden of cancer. However, cancer registry (CR) data are usually made available with substantial delay to ensure best possible completeness of case ascertainment. Here, we investigate empirically with routinely available data whether such a delay is mandatory for survival analyses or whether data can be used earlier to provide more up-to-date survival estimates. We compared distributions of prognostic factors and period relative survival estimates for three population-based CRs in Germany (Schleswig-Holstein (SH), Rhineland-Palatinate (RP), Saarland (SA)) computed on datasets extracted one (DY+1) to 5 years after the year of diagnosis (…

MaleOncologyCancer Researchmedicine.medical_specialtyTime FactorsPopulationCancer registrationEmpirical Research03 medical and health sciences0302 clinical medicineGermanyNeoplasmsInternal medicinemedicineHumansRegistrieseducationLung cancereducation.field_of_studyRelative survivalbusiness.industryCancer survivalmedicine.diseaseSurvival AnalysisCancer registryCase ascertainmentOncology030220 oncology & carcinogenesisFemalebusinessReference datasetInternational Journal of Cancer
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Repeatability of exhaled breath fingerprint collected by a modern sampling system in asthmatic and healthy children

2019

E-noses provide potential non-invasive metabolic biomarkers for diagnosing and monitoring pulmonary diseases. The primary aim of the present study was to assess the within-day and between-day repeatability of a modern breath sampling system (Pneumopipe® plus an array of e-nose sensors) in asthmatic and healthy children. The secondary aim was to compare the repeatability of the breath sampling system, spirometry and exhaled nitric oxide (eNO). Fifteen children (age 6-11 years) with asthma and thirty healthy children matched by age and gender (1:2 allocation) were recruited; of them, three healthy children did not complete the study. All measurements were collected twice during the baseline v…

MalePulmonary and Respiratory MedicineSpirometrymedicine.medical_specialtyspirometryRegistration systemNitric Oxide01 natural sciences03 medical and health sciences0302 clinical medicinechildrenInternal medicineStatistical significanceasthma children e-nose exhaled nitric oxide repeatability spirometrymedicineHumanse-noserepeatabilityChildAsthmamedicine.diagnostic_testbusiness.industry010401 analytical chemistryReproducibility of ResultsRepeatabilityasthmamedicine.disease0104 chemical sciencesSampling systemAsthmatic childrenBreath Tests030228 respiratory systemExhalationCase-Control StudiesExhaled nitric oxideexhaled nitric oxideFemaleFactor Analysis StatisticalbusinessJournal of Breath Research
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Determinants of CAT (COPD Assessment Test) scores in a population of patients with COPD in central and Eastern Europe: The POPE study

2019

Abstract Background The COPD Assessment Test (CAT) has been proposed to help guide therapy in chronic obstructive pulmonary disease (COPD). It is important to understand the distribution of scores in different COPD populations and their determinants. Methods The POPE study is an international, observational cross-sectional study of COPD subjects in 11 Central and Eastern European countries aimed at characterizing COPD phenotypes. Here we report the analysis of CAT scores with the objective of identifying their determinants, evaluating symptom load and investigating the distribution of scores among the participating countries. Additionally, we investigated the discrepancies between the CAT a…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyPopulationWalk TestComorbiditySeverity of Illness IndexPulmonary Disease Chronic Obstructive03 medical and health sciences0302 clinical medicineForced Expiratory VolumeInternal medicinePrevalencemedicineHumansEurope Eastern030212 general & internal medicineBulgariaTrial registrationeducationDepression (differential diagnoses)AgedHungaryeducation.field_of_studyCOPDDepressionbusiness.industryMiddle AgedExercise capacitymedicine.diseaseRespiratory Function Tests3. Good healthEastern europeanCross-Sectional Studies030228 respiratory systemPhysical EnduranceCopd assessment testFemaleObservational studySymptom AssessmentbusinessRespiratory Medicine
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A co-registration investigation of inter-word spacing and parafoveal preview: Eye movements and fixation-related potentials

2019

Participants’ eye movements (EMs) and EEG signal were simultaneously recorded to examine foveal and parafoveal processing during sentence reading. All the words in the sentence were manipulated for inter-word spacing (intact spaces vs. spaces replaced by a random letter) and parafoveal preview (identical preview vs. random letter string preview). We observed disruption for unspaced text and invalid preview conditions in both EMs and fixation-related potentials (FRPs). Unspaced and invalid preview conditions received longer reading times than spaced and valid preview conditions. In addition, the FRP data showed that unspaced previews disrupted reading in earlier time windows of analysis, com…

MaleTime FactorsEye MovementsPhysiologyVisual SystemVisionComputer scienceSpeech recognitionSensory PhysiologyVisual PhysiologySocial ScienceslukeminensilmänliikkeetOcular physiology0302 clinical medicineFovealMedicine and Health SciencesPsychologyAttentionMacula LuteaEEGNeurolinguisticsClinical NeurophysiologyBrain MappingMultidisciplinaryQ05 social sciencesRElectroencephalographyHealthy VolunteersSensory SystemsSemanticsElectrophysiologyBioassays and Physiological AnalysisPattern Recognition VisualBrain ElectrophysiologyPhysical SciencestekstinymmärtäminenMedicineFemaleSensory PerceptionAnatomyResearch ArticleAdultAdolescentImaging TechniquesPermutationScienceNeurophysiologyCo registrationNeuroimagingFixation OcularResearch and Analysis Methods050105 experimental psychologyYoung Adult03 medical and health sciencesHumans0501 psychology and cognitive sciencesScalpDiscrete MathematicsElectrophysiological TechniquesCognitive PsychologyBiology and Life SciencesEye movementLinguisticsReadingSentence ProcessingCombinatoricsFixation (visual)katseenseurantaCognitive ScienceClinical MedicineHeadMathematics030217 neurology & neurosurgeryNeurosciencePLOS ONE
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Extended-release guanfacine hydrochloride in 6-17-year olds with ADHD: a randomised-withdrawal maintenance of efficacy study.

2015

Background Extended-release guanfacine hydrochloride (GXR), a selective α2A-adrenergic agonist, is a nonstimulant medication for attention-deficit/hyperactivity disorder (ADHD). This phase 3, double-blind, placebo-controlled, randomised-withdrawal study evaluated the long-term maintenance of GXR efficacy in children/adolescents with ADHD. Methods Children/adolescents (6–17 years) with ADHD received open-label GXR (1–7 mg/day). After 13 weeks, responders were randomised to GXR or placebo in the 26-week, double-blind, randomised-withdrawal phase (RWP). The primary endpoint was the percentage of treatment failure (≥50% increase in ADHD Rating Scale version IV total score and ≥2-point increase …

Malemedicine.medical_specialtyAdolescentPlacebo03 medical and health sciences0302 clinical medicineDouble-Blind MethodRating scaleInternal medicineOutcome Assessment Health CareDevelopmental and Educational PsychologymedicineClinical endpointAdrenergic alpha-2 Receptor AgonistsHumansTreatment FailureGuanfacine HydrochloridePsychiatryTrial registrationChildTime to treatment failure030227 psychiatryGuanfacinePsychiatry and Mental healthAttention Deficit Disorder with HyperactivityDelayed-Action PreparationsPediatrics Perinatology and Child HealthFemaleExtended releasePsychology030217 neurology & neurosurgeryEfficacy StudyJournal of child psychology and psychiatry, and allied disciplines
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Is faster better? A randomised crossover study comparing algorithms for closed-loop automatic oxygen control

2019

ObjectiveClosed-loop automatic control (CLAC) of the fractional inspired oxygen (FiO2) improved oxygen administration to preterm infants on respiratory support. We investigated whether a revised CLAC algorithm (CLACfast, ≤2 FiO2 adjustments/min), compared with routine manual control (RMConly), increased the proportion of time with arterial haemoglobin oxygen saturation measured by pulse oximetry within prespecified target ranges (Target%) while not being inferior to the original algorithm (CLACslow: ≤0.3 FiO2 adjustments/min).DesignUnblinded randomised controlled crossover study comparing three modes of FiO2 control in random order for 8 hours each: RMC supported by CLACfast was compared wi…

Malemedicine.medical_specialtyAutomationIntensive caremedicineHumansOximetryNeonatologyTrial registrationCross-Over Studiesmedicine.diagnostic_testbusiness.industryInfant NewbornOxygen Inhalation TherapyOutcome measuresObstetrics and GynecologyGestational ageGeneral MedicineCrossover studyOxygenPulse oximetryPediatrics Perinatology and Child HealthFemalebusinessClosed loopAlgorithmAlgorithmsInfant PrematureArchives of Disease in Childhood - Fetal and Neonatal Edition
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GRASP & evolutionary path relinking for medical image registration based on point matching

2010

Image registration is a very active research area in computer vision. Image registration methods, aim to find a transformation between two images taken under different conditions. Point matching is an image registration approach based on searching for the right pairing of points between the two images. From this matching, the registration transformation can be inferred by means of numerical methods. In this paper, we tackle the medical image registration problem adapting a new advanced hybrid metaheuristic composed by the GRASP and the evolutionary path relinking algorithms, called G&EvPR. The experiments conducted in this work have shown the good performance of G&EvPR compared to similar a…

Matching (statistics)business.industryGRASPComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONImage registrationPoint set registrationEvolutionary computationElectronic mailComputer visionArtificial intelligencebusinessMetaheuristicGreedy randomized adaptive search procedureMathematicsIEEE Congress on Evolutionary Computation
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Accurate registration of random radiographic projections based on three spherical references for the purpose of few-view 3D reconstruction

2008

Precise registration of radiographic projection images acquired in almost arbitrary geometries for the purpose of three-dimensional (3D) reconstruction is beset with difficulties. We modify and enhance a registration method [R. Schulze, D. D. Bruellmann, F. Roeder, and B. d'Hoedt, Med. Phys. 31, 2849-2854 (2004)] based on coupling a minimum amount of three reference spheres in arbitrary positions to a rigid object under study for precise a posteriori pose estimation. Two consecutive optimization procedures (a, initial guess; b, iterative coordinate refinement) are applied to completely exploit the reference's shadow information for precise registration of the projections. The modification h…

Mathematical optimizationProjection (mathematics)Iterative method3D reconstructionImage registrationA priori and a posterioriImage processingGeneral MedicineIterative reconstructionAlgorithmPoseMathematicsMedical Physics
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Seawater carbonate chemistry and nest guarding behaviour of a temperate wrasse

2021

Organisms may respond to changing environmental conditions by adjusting their behaviour (i.e., behavioural plasticity). Ocean acidification (OA), resulting from anthropogenic emissions of carbon dioxide (CO2), is predicted to impair sensory function and behaviour of fish. However, reproductive behaviours, and parental care in particular, and their role in mediating responses to OA are presently overlooked. Here, we assessed whether the nesting male ocellated wrasse Symphodus ocellatus from sites with different CO2 concentrations showed different behaviours during their breeding season. We also investigated potential re-allocation of the time-budget towards different behavioural activities b…

Ocean Acidification International Coordination Centre (OA-ICC)IdentificationPotentiometric titrationRegistration number of speciesSalinityTemperateCalcite saturation statePotentiometricinorganicwaterAlkalinitySiteTemperature waterCarbon inorganic dissolvedUniform resource locator/link to referenceCalculated using seacarb after Nisumaa et al 2010Mediterranean SeaOcean Acidification International Coordination Centre OA ICCAnimaliaAragonite saturation stateBehaviourBicarbonate ionTime in secondsTypeNektonAlkalinity totalChordataCalculated using seacarb after Nisumaa et al. (2010)totalCO2 ventSpeciespHPelagosSymphodus ocellatusTemperatureCarbonate system computation flagdissolvedFugacity of carbon dioxide (water) at sea surface temperature (wet air)Carbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)CarbonPartial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideSingle speciesEarth System ResearchFugacity of carbon dioxide water at sea surface temperature wet airCoast and continental shelfField observationUniform resource locator link to reference
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Seawater carbonate chemistry and shell mineralogy, microstructure, and mechanical strength of four Mediterranean gastropod species near a CO2 seep

2017

Marine CO2 seeps allow the study of the long-term effects of elevated pCO2 (ocean acidification) on marine invertebrate biomineralization. We investigated the effects of ocean acidification on shell composition and structure in four ecologically important species of Mediterranean gastropods (two limpets, a top-shell snail, and a whelk). Individuals were sampled from three sites near a volcanic CO2 seep off Vulcano Island, Italy. The three sites represented ambient (8.15 pH), moderate (8.03 pH) and low (7.73 pH) seawater mean pH. Shell mineralogy, microstructure, and mechanical strength were examined in all four species. We found that the calcite/aragonite ratio could vary and increased sign…

Ocean Acidification International Coordination Centre (OA-ICC)IdentificationRegistration number of speciesSalinityTemperateinorganicAlkalinityExperimentTemperature waterCarbon inorganic dissolvedCalculated using seacarb after Nisumaa et al 2010Aragonite saturation stateAlkalinity totalSalinity standard errorPatella caeruleatotalCO2 ventpHCalciteTemperaturePartial pressure of carbon dioxide (water) at sea surface temperature (wet air) standard errordissolvedCarbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)standard errorEarth System ResearchField observationUniform resource locator link to referencePotentiometric titrationCalcite saturation stateLengthLocationPotentiometricwaterGrowth MorphologyHexaplex trunculusAlkalinity total standard errorBenthosUniform resource locator/link to referenceOsilinus turbinatusOther studied parameter or processMediterranean SeaOcean Acidification International Coordination Centre OA ICCAnimaliaBicarbonate ionTypeTemperature water standard errorCalculated using seacarb after Nisumaa et al. (2010)ForceSpeciespH standard errorCalculated using CO2SYSCarbonate system computation flagFugacity of carbon dioxide (water) at sea surface temperature (wet air)CarbonElasticityTreatmentAragonite saturation state standard errorPartial pressure of carbon dioxide water at sea surface temperature wet airAragoniteCarbon dioxideMolluscaGrowth/MorphologySingle speciesBenthic animalsFugacity of carbon dioxide water at sea surface temperature wet airPatella rusticaToughnessCoast and continental shelf
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