Search results for "Regression"
showing 10 items of 2619 documents
Sparse relative risk regression models
2020
Summary Clinical studies where patients are routinely screened for many genomic features are becoming more routine. In principle, this holds the promise of being able to find genomic signatures for a particular disease. In particular, cancer survival is thought to be closely linked to the genomic constitution of the tumor. Discovering such signatures will be useful in the diagnosis of the patient, may be used for treatment decisions and, perhaps, even the development of new treatments. However, genomic data are typically noisy and high-dimensional, not rarely outstripping the number of patients included in the study. Regularized survival models have been proposed to deal with such scenarios…
A Comment on the Coefficient of Determination for Binary Responses
1992
Abstract Linear logistic or probit regression can be closely approximated by an unweighted least squares analysis of the regression linear in the conditional probabilities provided that these probabilities for success and failure are not too extreme. It is shown how this restriction on the probabilities translates into a restriction on the range of the coefficient of determination R 2 so that, as a consequence, R 2 is not suitable to judge the effectiveness of linear regressions with binary responses even if an important relation is present.
Bayesian subset selection for additive and linear loss function
1979
Given k independent samples of common size n from k populations πj,…,πk with distribution the problem is to select a non-empty subset form {πj,…,πk}, which is associated with "good" (large) θ-values. We consider this problem from a Bayesian approach. By choosing additive and especially linear loss functions we try to fill a gap lying in between the results of Deely and Gupta (1968) and more recent papers due to Goel and Rubin (1977), Gupta and Hsu (1978) and other authors. It is shown that under acertain "normal model" Seal's procedure turns out to be Bayes w.r.t. an unrealistic loss function where as Gupta's maximunl means procedure turns out to be ( for large n) asymptotically Bayes w.r. …
Parametric estimation of non-crossing quantile functions
2021
Quantile regression (QR) has gained popularity during the last decades, and is now considered a standard method by applied statisticians and practitioners in various fields. In this work, we applied QR to investigate climate change by analysing historical temperatures in the Arctic Circle. This approach proved very flexible and allowed to investigate the tails of the distribution, that correspond to extreme events. The presence of quantile crossing, however, prevented using the fitted model for prediction and extrapolation. In search of a possible solution, we first considered a different version of QR, in which the QR coefficients were described by parametric functions. This alleviated th…
Migration and students' performance: detecting geographical differences following a curves clustering approach
2020
Students’ migration mobility is the new form of migration: students migrate to improve their skills and become more valued for the job market. The data regard the migration of Italian Bachelors who enrolled at Master Degree level, moving typically from poor to rich areas. This paper investigates the migration and other possible determinants on the Master Degree students’ performance. The Clustering of Effects approach for Quantile Regression Coefficients Modelling has been used to cluster the effects of some variables on the students’ performance for three Italian macro-areas. Results show evidence of similarity between Southern and Centre students, with respect to the Northern ones.
Modeling temperature effects on mortality: multiple segmented relationships with common break points.
2008
We present a model for estimation of temperature effects on mortality that is able to capture jointly the typical features of every temperature-death relationship, that is, nonlinearity and delayed effect of cold and heat over a few days. Using a segmented approximation along with a doubly penalized spline-based distributed lag parameterization, estimates and relevant standard errors of the cold- and heat-related risks and the heat tolerance are provided. The model is applied to data from Milano, Italy.
Analyzing Temperature Effects on Mortality Within theREnvironment: The Constrained Segmented Distributed Lag Parameterization
2010
Here we present and discuss the R package modTempEff including a set of functions aimed at modelling temperature effects on mortality with time series data. The functions fit a particular log linear model which allows to capture the two main features of mortality- temperature relationships: nonlinearity and distributed lag effect. Penalized splines and segmented regression constitute the core of the modelling framework. We briefly review the model and illustrate the functions throughout a simulated dataset.
Delay in claim settlement and ruin probability approximations
1995
We introduce a general risk model for portfolios with delayed claims which is a natural extension of the classical Poisson model. We investigate ruin problems for different premium principles and provide approximations for the ruin probability. We conclude with some specific models, for example, for IBNR portfolios and portfolios where the pay-off process depends on the claim size.
A spatially filtered mixture of β-convergence regressions for EU regions, 1980–2002
2007
Assessing regional growth and convergence across Europe is a matter of primary relevance. Empirical models that do not account for structural heterogeneities and spatial effects may face serious misspecification problems. In this work, a mixture regression approach is applied to the beta-convergence model, in order to produce an endogenous selection of regional growth patterns. A priori choices, such as North-South or centre-periphery divisions, are avoided. In addition to this, we deal with the spatial dependence existing in the data, applying a local filter to the data. The results indicate that spatial effects matter, and either absolute, conditional, or club convergence, if extended to …
Bayesian hierarchical Poisson models with a hidden Markov structure for the detection of influenza epidemic outbreaks
2015
Considerable effort has been devoted to the development of statistical algorithms for the automated monitoring of influenza surveillance data. In this article, we introduce a framework of models for the early detection of the onset of an influenza epidemic which is applicable to different kinds of surveillance data. In particular, the process of the observed cases is modelled via a Bayesian Hierarchical Poisson model in which the intensity parameter is a function of the incidence rate. The key point is to consider this incidence rate as a normal distribution in which both parameters (mean and variance) are modelled differently, depending on whether the system is in an epidemic or non-epide…