Search results for "Regulatory"
showing 10 items of 740 documents
LA DIR. 2020/1828/UE SULLE AZIONI RAPPRESENTATIVE E IL “SISTEMA DELLE PROVE”. LA PROMOZIONE DELL’INTERESSE PUBBLICO ATTRAVERSO LA TUTELA DEGLI INTERE…
2022
The EU Directive 2020/1828 is the arrival point of a troubled harmo-nization process on collective techniques for consumers’ protection, no longer limited to injunctive measures but also extended to redress ones. The essay focuses on the two provisions dedicated, respec-tively, to the binding effects of jurisdictional/ administrative decisions as well as to the exhibition orders. The Author stresses how, through those legislative measures and despite the uncertainties still related to the ongoing implementation process, a European Regulatory Pri-vate Law enforcement is being shaped more and more oriented to the consistency between its “private” and “public”dimension.
cis-Regulation and chromatin dynamics of the hbox12 gene during the embryogenesis of Paracentrotus lividus.
2014
The GRN specifying the dorsal-ventral (D-V) axis of the sea urchin embryo is currently under investigation. An early input for D-V polarity is given by a redox gradient probably generated by an asymmetrical distribution of maternal mitochondria (1). Only on the future ventral side, the oxidizing environment induces the expression of the nodal gene, an essential regulator of D-V polarization (2). By contrast, on the future dorsal side, a reducing environment activates the hypoxia inducible factor (HIF-1α) (3). The hbox12 transcription repressor is an early marker of the dorsal side of the embryo, in which it negatively regulates the expression of nodal (4, 5). Interestingly, by in silico ana…
Zakorzenienie gospodarstw rolnych w lokalnych (regionalnych) systemach biobiznesu – uwarunkowania instytucjonalne w województwie opolskim
2016
Celem opracowania jest wskazanie na rolę instytucji w kreowaniu lokalnych (regionalnych) biobiznesów. Lokalne biobiznesy opierają się na unikatowym wykorzystaniu zarówno standardowych, jak i specyficznych zasobów terytoriów, w których są zakładane. Analizę przeprowadzono z wykorzystaniem trzech wymiarów transformacji europejskiego modelu rolnictwa: regulacji środowiskowych, dyfuzji wiedzy i informacji oraz powiązań międzyorganizacyjnych i społecznych. Na podstawie przeprowadzonych badań ankietowych zidentyfikowano stopień zakorzenienia instytucji zarządzających powstaniem biogospodarki w sieciach społecznych użytkowników towarowych gospodarstw rolnych w województwie opolskim. Praca ma chara…
Maturation of Epidermal Langerhans Cells In Vitro Is Accompanied by Downregulation of 4F2 (CD98) as Determined by Differential Display
1998
Following short-term culture, Langerhans cells mature morphologically and functionally into potent immunostimulatory cells. As regulation of gene expression accompanies this maturation process, it is likely that differentially expressed genes are involved in the maturation events. Using the recently described method of differential display, we generated cDNA expression patterns starting with mRNA of murine epidermal Langerhans cells isolated either directly (fLC) or following 3 d cultivation (cLC). Five hundred putative differentially expressed cDNA fragments were recovered from the gel. For a part of the fragments differential expression was confirmed by dot blot and Southern hybridization…
Reflexions on the introduction of the vocabulary of regulation in the field of law during the XVIIIth century and on its contemporary use
2017
According to a recurring lesson, the vocabulary of regulation would be of late introduction in the law language. Indeed, law professors substantiate this theory, conveyed by the sociologists : this word family would have first been introduced by the social sciences at the end of the XIXth century, before any use by the world of law. The present study tends, on the contrary, to demonstrate the existence and the continuity of the idea of regulation in law since the introduction, in the XVIIIth century, of the polysemous figure of the regulator ; a two-headed figure, applied as well to a power as to a judicial institution and to law, which separates and sometimes involves the regulation of a m…
El impacto del cambio climático en la movilidad humana : las migraciones climáticas en el contexto internacional y europeo
2021
For decades, the migration phenomenon has been one of the thorniest regulatory issues in the European Union (EU) policy. In addition, today, the fight against climate change in all regions of the world makes the situation worse for the new ?climate refugees? or ?environmental displaced people?, whose legal status is not yet covered by the ancient 1951 Refugee Convention.
Self-regulatory efficacy and sources of efficacy in elementary school pupils: Self-regulatory experiences in a population sample and pupils with atte…
2019
In this study, we examined self-regulatory efficacy and sources of self-efficacy (mastery experiences, vicarious experiences, social persuasion and physiological/emotional states) and the relationships between self-efficacy and its sources among elementary school pupils. Two groups were compared: a population sample (PS, N = 1284) and pupils with difficulties in attention and executive functions (AED, N = 61). Data gathered from self-report questionnaires indicated that pupils in the PS group had more positive efficacy beliefs and mastery experiences and fewer negative physiological/emotional states than the AED group. Analyses showed strong connections between sources and self-regulatory e…
Interferon α interferes with immunological tolerance.
2013
The ability of regulatory T cells (Tregs) to promote immunological tolerance represents an important obstacle in cancer immunotherapy. We have recently discovered that the clinically established immunotherapeutic agent interferon α (IFNα) inactivates the suppressive functions of human Tregs. Here, we outline the mechanisms whereby IFNα mediates this important function and discuss its therapeutic implications for cancer immunotherapy.
The Developmental Transcriptome for Lytechinus variegatus Exhibits Temporally Punctuated Gene Expression Changes
2019
AbstractEmbryonic development is arguably the most complex process an organism undergoes during its lifetime, and understanding this complexity is best approached with a systems-level perspective. The sea urchin has become a highly valuable model organism for understanding developmental specification, morphogenesis, and evolution. As a non-chordate deuterostome, the sea urchin occupies an important evolutionary niche between protostomes and vertebrates.Lytechinus variegatus(Lv) is an Atlantic species that has been well studied, and which has provided important insights into signal transduction, patterning, and morphogenetic changes during embryonic and larval development. The Pacific specie…