Search results for "Relations"

showing 10 items of 6949 documents

Implications of Managerial Framing of Stakeholders in Environmental Reports

2014

Corporate environmental reports are increasingly viewed as products of the managerial framing of responsibility and stakeholders. This notion encouraged us to conduct a multiple case study on how stakeholders are framed in environmental reports. We show how interaction between companies and stakeholders is described in the environmental reports of three firms operating in different business sectors – financial, aviation and energy – over a period of five years. We use an inductively oriented content analysis to identify five categories of relationships being constructed in the data: demanding, promoting, committing, donating and preventing. We then show how commitment and promotion dominate…

Aviationbusiness.industryStakeholderCorporate environmentalismPublic relationsyrityksetFraming (social sciences)Content analysisAccountingAccountabilityBusiness sectorMultiple caseMarketingbusinessympäristöraportointita512
researchProduct

A combined experimental and theoretical study of the thermal cycloaddition of aryl azides with activated alkenes.

2011

International audience; Reactions were performed from aryl azides on the one hand, and activated alkenes coming from β-dicarbonyl compounds or malonodinitrile on the other hand, either with recourse to conventional heating or to microwave activation, to afford 1-aryl-1H-1,2,3-triazoles. The mechanism and the regioselectivity of the reactions involving β-dicarbonyl compounds have been theoretically studied using DFT methods at the B3LYP/6-31G* level: they are domino processes comprising a tautomeric equilibrium of the β-dicarbonyl compounds with their enol forms, a 1,3-dipolar cycloaddition of the enol forms with the aryl azides (high activation energy), and a dehydration process (lower acti…

AzidesAntifungal AgentsAntineoplastic AgentsMicrobial Sensitivity TestsActivation energyAlkenes010402 general chemistryPhotochemistry01 natural sciencesBiochemistryStructure-Activity Relationshipchemistry.chemical_compoundCell Line TumorThermalHumansPhysical and Theoretical ChemistryMicrowavesMolecular Structure010405 organic chemistry[CHIM.ORGA]Chemical Sciences/Organic chemistryArylOrganic ChemistryTemperatureRegioselectivityStereoisomerismTriazolesEnolCombinatorial chemistryTautomerCycloadditionAnti-Bacterial Agents0104 chemical sciences[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistrychemistryCyclizationQuantum TheoryDegradation (geology)Drug Screening Assays Antitumor
researchProduct

A new method of anomeric protection and activation based on the conversion of glycosyl azides into glycosyl fluorides

1993

Glycosyl azides provide reliable anomeric protection stable to conditions for hydrolytic removal of ester groups, for reductive opening or release of acetalic diol protection, for the introduction of ether-type protection, and for glycosylation processes. The utility of this anomeric protection is further enhanced as glycosyl azides may be converted into glycosyl fluorides, which can be activated for glycosylation reactions. To this end, glycosyl azides have been subjected to 1,3-dipolar cycloaddition with di-tert-butyl acetylenedicarboxylate. On treatment with hydrogen fluoride-pyridine complex the N-glycosyl triazole derivatives directly give glycosyl fluorides.

AzidesMagnetic Resonance Spectroscopyanimal structuresAnomerGlycosylationOptical RotationMolecular Sequence DataCarbohydrate synthesismacromolecular substancesBiochemistryKoenigs–Knorr reactionAnalytical ChemistryFluoridesStructure-Activity Relationshipchemistry.chemical_compoundCarbohydrate ConformationOrganic chemistryGlycosylGlycosidesGlycosyl donorMolecular StructureOrganic ChemistryChemical glycosylationGlycosyl acceptorGeneral Medicinecarbohydrates (lipids)Carbohydrate Sequencechemistrylipids (amino acids peptides and proteins)Carbohydrate Research
researchProduct

How to increase company loyalty: using relational variables and sustainable practices to segment the maritime transport sector

2022

Intense competition in goods transportation has highlighted theimportance of understanding customers’interests in order to designsuccessful relationship strategies. This study proposes, through asegmentation approach, to identify customer groups based on theirperceptions of sustainable practices and relational variables abouttheir main transport supplier. From a sample of 122 companies, amultiple correspondence analysis was carried out. The results showthat there are three groups of customer companies, which corres-pond to a high, low, and medium relational and sustainabilityapproach. The identified segments are also significantly different interms of time of operation in the maritime secto…

B2B relationshipEconomics and Econometricslogistics valuelong-termorientationsegmentationUNESCO::CIENCIAS ECONÓMICASsustainable practicesEconomic Research-Ekonomska Istraživanja
researchProduct

Communication structure and collective actions in social media

2010

In this paper I present results a study of different types of social media communication and networking channels that allow for collective action (CA): Twitter, Jaiku / Qaiku, Ning and Facebook. My preliminary findings indicate, that the visual outlining and the structure of communication create different kinds of collectivity and collective actions. A status stream is effective for simple and fast repetitive mass actions and for individual mass broadcasting, while channels and threads are needed as a backchannel for more complicated, coordinated and iterative tasks and support a sense of community. When planning collective action on the Internet, ranging from citizen participation to marke…

Backchannelbusiness.industryPolitical scienceReal-time webSense of communityCollective intelligenceThe InternetSocial mediaPublic relationsbusinessCollective actionCrowdsourcingProceedings of the 14th International Academic MindTrek Conference: Envisioning Future Media Environments
researchProduct

The Southern African Development Community (SADC): An Analytical Overview of Its History, Policies and Institutional Framework

2017

This chapter gives fundamental background information about the history and development of regionalism in Southern Africa and about the current state of the SADC as a modern regional integration organisation. In terms of an analytical overview, Muntschick reflects briefly on the formation, character and objectives of the region’s old regionalisms such as the Southern African Customs Union (SACU), the Frontline States (FLS) and particularly the Southern African Development Co-ordination Conference (SADCC) as predecessors of the SADC. Also, this chapter turns to the new regionalism and provides detailed information on the SADC as an organisation, its member states, key agenda and central poli…

Background informationCustoms unionState (polity)Environmental protectionmedia_common.quotation_subjectMember statesPolitical scienceRegional integrationRegionalism (international relations)Regional sciencemedia_common
researchProduct

Electrophysiological evidence for heptameric stoichiometry of ion channels formed by Staphylococcus aureus alpha-toxin in planar lipid bilayers.

2000

Staphylococcal alpha-toxin forms homo-oligomeric channels in lipid bilayers and cell membranes. Here, we report that electrophysiological monitoring of single-channel function using a derivatized cysteine substitution mutant allows accurate determination of the subunit stoichiometry of the oligomer in situ. The electrophysiological phenotype of channels formed in planar lipid bilayers with the cysteine replacement mutant I7C is equal to that of the wild type. When pores were formed with I7C, alterations of several channel properties were observed upon modification with SH reagents. Decreases in conductance then occurred that were seen only as negative voltage was applied. At the level of si…

Bacterial ToxinsLipid BilayersWild typeConductanceBiologyMicrobiologyOligomerIon ChannelsElectrophysiologychemistry.chemical_compoundHemolysin ProteinsStructure-Activity RelationshipMembranechemistryBiochemistryMutationBiophysicsCysteineLipid bilayerMolecular BiologyIon channelStaphylococcus aureus alpha toxinCysteineMolecular microbiology
researchProduct

Delineation of the catalytic domain of Clostridium difficile toxin B-10463 to an enzymatically active N-terminal 467 amino acid fragment.

2006

Abstract In an attempt to directly approach the postulated toxic domain of Clostridium difficile 's TcdB-10463, eight subclones of different size and locations in the N-terminal third of the toxin were generated. Expression of these toxin fragments was checked in Western blots and the enzymatic activity of the expressed proteins was analyzed by glucosylating Ras related small GTP-binding proteins. Two polypeptides of 875 aa (TcdBc1–3) and 557 aa (TcdBc1-H) glucosylated their targets Rho, Rac and Cdc42 with the same activity and specificity as the holotoxin. In comparison 516 aa (TcdBc1-N) and 467 aa (TcdBc1-A) protein fragments exhibited highly reduced activity, while Tcdc1 and TcdB2–3 (aa …

Bacterial ToxinsMolecular Sequence DataClostridium difficile toxin Bmedicine.disease_causeMicrobiologyStructure-Activity RelationshipGTP-binding protein regulatorsClostridiumBacterial ProteinsGeneticsmedicineMolecular Biologychemistry.chemical_classificationBinding SitesbiologyBase SequenceToxinbiology.organism_classificationMolecular biologyPeptide FragmentsRecombinant ProteinsAmino acidEnzymechemistryCdc42 GTP-Binding ProteinBiochemistryGlucosyltransferasesbiology.proteinGlucosyltransferaseFEMS microbiology letters
researchProduct

La construcción de los límites a la libertad de expresión en las redes sociales

2016

La generalización de las comunicaciones electrónicas, junto a otras muchas transformaciones, ha facilitado enormemente tanto la comunicación interpersonal como la participación en el debate público a cualquier ciudadano. Como resultado, el pluralismo se ha visto indudablemente enriquecido, así como las posibilidades de recibir información y ser miembro activo de la comunidad política. Otras consecuencias de esta transformación, sin embargo, presentan algunas aristas. Así, esta ampliación del espacio público ha limitado también los espacios de estricta privacidad, incluyendo aquellos ámbitos donde históricamente la expresión de todo tipo de ideas y opiniones quedaban en la intimidad, que cad…

Balance (metaphysics)InternetSociology and Political ScienceLlibertat d'expressiómedia_common.quotation_subjectPublic debateInterpersonal communicationHatredXarxes socialsPublic spaceExtension (metaphysics)Expression (architecture)Political sciencePolitical Science and International RelationsDiversity (politics)media_commonLaw and economics
researchProduct

The European Courts and the Security Council: Between "Dédoublement Fonctionnel" and Balancing of Values

2009

The recent case law of various international tribunals facing questions related to UN Security Council resolutions shows the clear tendency to grant primacy to the UN legal order. This trend, far from being well founded on formal arguments, appears to be a tribute to a legal order perceived as superior, and, at the same time, is revealing of the ‘value oriented’ approach followed by the courts. Such an approach can be categorized from a theoretical perspective in the light of Scelle's theory of relations between legal orders, whereby the courts implement in their respective legal orders values stemming from the UN legal order. Various critical remarks can be advanced in relation to this att…

Balance (metaphysics)Security interestValue (ethics)Human rightsmedia_common.quotation_subjectCommon lawAppealrelations between legal orders primacy of UN legal order balancing of values human rights security interestDédoublement fonctionnelBalancing of ValuesOrder (exchange)LawPolitical Science and International Relationsprimacy of the UN legal order European Court of human Rights European Court of Justice Kadi case Behrami and Saramati case balancing of interests security interest v. human rightsEuropean Court of JusticeSociologyRelation (history of concept)European Court of Human RightsLawSettore IUS/14 - DIRITTO DELL'UNIONE EUROPEAUN Security Councilmedia_commonSettore IUS/13 - DIRITTO INTERNAZIONALE
researchProduct