Search results for "Replacement"

showing 10 items of 561 documents

Plausible Role of Estrogens in Pathogenesis, Progression and Therapy of Lung Cancer

2021

Malignant neoplasms are among the most common diseases and are responsible for the majority of deaths in the developed world. In contrast to men, available data show a clear upward trend in the incidence of lung cancer in women, making it almost as prevalent as breast cancer. Women might be more susceptible to the carcinogenic effect of tobacco smoke than men. Furthermore, available data indicate a much more frequent mutation of the tumor suppressor gene-p53 in non-small cell lung cancer (NSCLC) female patients compared to males. Another important factor, however, might lie in the female sex hormones, whose mitogenic or carcinogenic effect is well known. Epidemiologic data show a correlatio…

p53MaleLung NeoplasmsHealth Toxicology and Mutagenesismedicine.medical_treatmentlcsh:MedicineEstrogen receptorReviewNSCLCsex hormonessex hormone03 medical and health sciences0302 clinical medicineBreast cancerA549Carcinoma Non-Small-Cell LungmedicineCarcinomaestrogenNeoplasmEstrogen Receptor betaHumansLung cancerCarcinogennon-small cell lung cancer030304 developmental biology0303 health sciencesLungbusiness.industrylcsh:RPublic Health Environmental and Occupational Health17β-estradiolEstrogen Receptor alphaHormone replacement therapy (menopause)Estrogensmedicine.diseaselung adenocarcinomarespiratory tract diseaseslung cancermedicine.anatomical_structure17- estradiolReceptors Estrogen030220 oncology & carcinogenesisCancer researchFemalebusinessestrogen receptorInternational Journal of Environmental Research and Public Health
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Current status and prospects conservative stem prostheses in hip-replacement surgery

2011

prostheses conservative stemhip replacement surgery proxima stem implantSettore MED/33 - Malattie Apparato Locomotore
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RED BLOOD CELL DISTRIBUTION WIDTH PREDICTS MORBIDITY AND MORTALITY AFTER AORTIC VALVE REPLACEMENT

2014

Objective: Red blood cell distribution width (RDW), is a measurement of the size variation as well as an erythrocyte heterogeneity index (i.e., anysocytosis). used in combination with the mean corpuscular volume for anemia diagnosis. However, it is emerging as an useful predictor biomarker of mortality and morbidity of cardiovascular diseases. However, until now no literature data there are about the RDW role in predicting mortality after aortic valve replacement (AVR). Thus, in this pilot study biological significance of elevated RDW values in early outcome following AVR was evaluated Methods: We enrolled 75 patients (mean age 73.5 ±7.9 years) subjected to AVR and/ or not co temporally to …

red distribution width aortic valve replacement mortality and morbiditySettore MED/05 - Patologia ClinicaSettore MED/23 - Chirurgia Cardiaca
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Definition of Water Meter Substitution Plans based on a Composite Indicator

2014

This paper presents a water meter substitution plan based on a composite "Replacement indicator" which was defined and compared with common substitution strategies based on meter age and on run-to-fail approaches. The methodology was applied to one of the 17 sub-networks in which the Palermo city water distribution network (Italy) is divided. The analysis was carried out considering a substitution budget limitation and the results showed that the use of "Replacement indicator" outperform the classical substitution strategies based on meter age because it takes into account some other variables that may affect meter precision and wearing. (C) 2013 The Authors. Published by Elsevier Ltd.

replacement strategyEngineeringDistribution networksbusiness.industrySubstitution (logic)General MedicinePlan (drawing)Composite indicatorCivil engineeringwater metersForensic engineeringApparent losseswater distribution systemsMetreApparent lossebusinesswater distribution systemEngineering(all)metering errorProcedia Engineering
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Shoulder replacement in the treatment of pluri-fragmentary and displaced fractures of the proximal humerus: our experience

2011

shoulder replacement proximal humerusSettore MED/33 - Malattie Apparato Locomotore
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bbFISH-ing in the sonication fluid

2019

Abstract By 2030, the annual number of combined total hip and knee arthroplasty is estimated to reach 3.5 to 4 million in the US alone. In the context of a constant increase of the number of primary and revision total hip and knee arthroplasty, an increased risk of complication is expected. Prosthetic joint infections (PJIs) represent major cause of healthcare expenditure and morbidity. PJI still remain the most common and feared arthroplasty complication. A rapid and correct diagnosis of infection is decisive for a correct therapeutical management. In this setting, the Academic Emergency Hospital Sibiu adopted and implemented, with the beginning of September 2016, a new strategy for the di…

sonicationMaleProsthetic joint infectionmedicine.medical_specialtyPJIProsthesis-Related InfectionsArthroplasty Replacement Hipmedicine.medical_treatmentSonication7100Observational StudydiagnosticContext (language use)biofilm03 medical and health sciences0302 clinical medicineStaphylococcus epidermidisRNA Ribosomal 16SInternal medicineSynovial FluidmedicineHumans030212 general & internal medicineArthroplasty Replacement KneeIn Situ Hybridization FluorescenceAgedAged 80 and overBacteriological Techniquesbiologybusiness.industryRalstonia pickettiimolecular diagnosticBacterial InfectionsGeneral MedicineGold standard (test)Middle Agedbiology.organism_classificationArthroplastyRNA BacterialConnective Tissue030220 oncology & carcinogenesisPositive culturebbFISHFemaleComplicationbusinessResearch ArticleMedicine
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Evaluation of asset replacement strategies considering economic cycles: lessons from the machinery rental business

2015

Contains fulltext : 144492.pdf (Publisher’s version ) (Open Access) In businesses with heavy capital investments, the effective management of assets is crucial, in particular in the fleet rental business where assets are the major source of revenues. One important question in this regard concerns the replacement of used assets and the purchase of new assets. Thus, the objective of this study is to evaluate performance effects of asset replacement strategies. In order to maximise net cash flow of a rental company for construction machinery, a range of scenarios investigating the timing and nature of policies for replacing the fleet are analysed. Simulation findings are then discussed to gene…

system dynamicFinancereplacement strategysimulation modeleconomic cycle.business.industryResponsible Organizationrental industryRentingCommerceSettore SECS-P/07 - Economia AziendaleCapital (economics)asset managementFixed assetRevenueCash flowAsset managementAsset (economics)businesspolicyUtilizationInternational Journal of Modelling in Operations Management
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Replacing Project Managers in Information Technology Projects

2015

According to anecdotal evidence, project managers working on information technology (IT) projects are occasionally replaced, although the literature on information systems (IS) and project management (PM) makes little mention of it. With a view to narrowing this knowledge gap the authors examined the reasons behind the practice. The authors took an interpretive approach to the data gathering and analysis, and collected descriptions about replacing project managers (RPM) from interviews and questionnaires (n=43). The concept of contradiction served as a lens through which to identify the underlying reasons. Contradiction refers to statements asserting or expressing the opposite of another st…

ta113EngineeringKnowledge managementData collectionbusiness.industryIT project managementmedia_common.quotation_subjectContradictionsReplacementProject managerInformation technologyContext (language use)Public relationsTurnoverManagement of Technology and InnovationPhenomenonComputer Science (miscellaneous)Information systemContradictionProject managementbusinessta512Anecdotal evidencemedia_commonInternational Journal of Human Capital and Information Technology Professionals
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Prognostic Factors in Staged Bilateral Total Knee Arthroplasty—A Retrospective Case Series Analysis

2023

Background: Bilateral osteoarthritis of the knee is an indication for a bilateral total knee replacement (TKR) procedure. The goal of our study was to assess the sizes of the implants used during the first and second stages of TKR procedures in order to compare their size and identify the prognostic factors for the second procedure. Methods: We evaluated 44 patients who underwent staged bilateral TKR procedures. We assess the following prognostic factors from the first and second surgery: duration of anesthesia, femoral component size, tibial component size, duration of hospital stay, tibial polyethylene insert size, and the number of complications. Results: All assessed prognostic factors …

total knee replacement; two-stage; prognostic factors; bilateral; predictive factorsGeneral MedicineJournal of Clinical Medicine; Volume 12; Issue 10; Pages: 3547
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Asymmetrical muscle strength deficit, mobility limitation and aquatic resistance training in persons with knee osteoarthritis

2013

vesiliikuntanivelrikkoaquatic resistance trainingpolvettekoniveletosteoarthritismobility limitationasymmetrical muscle deficitknee replacementasymmetriarajoituksetvoimaharjoitteluliikkuminenlihasvoima
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