Search results for "Repo"
showing 10 items of 2753 documents
Prevalence and Correlates of Physical activity in a sample of UK adults observing social distancing during the COVID-19 pandemic
2020
ObjectiveTo investigate the levels and correlates of physical activity during COVID-19 social distancing in a sample of the UK public.MethodsThis paper presents analyses of data from a cross-sectional study. Levels of physical activity during COVID-19 social distancing were self-reported. Participants also reported on sociodemographic and clinical data. The association between several factors and physical activity was studied using regression models.ResultsNine hundred and eleven adults were included (64.0% were women and 50.4% of the participants were aged 35–64 years). 75.0% of the participants met the physical activity guidelines during social distancing. Meeting these guidelines during …
Integrated CGH/WES Analyses Advance Understanding of Aggressive Neuroblastoma Evolution: A Case Study
2021
Neuroblastoma (NB) is the most common extra-cranial malignancy in preschool children. To portray the genetic landscape of an overly aggressive NB leading to a rapid clinical progression of the disease, tumor DNA collected pre- and post-treatment has been analyzed. Array comparative genomic hybridization (aCGH), whole-exome sequencing (WES), and pharmacogenetics approaches, respectively, have identified relevant copy number alterations (CNAs), single nucleotide variants (SNVs), and polymorphisms (SNPs) that were then combined into an integrated analysis. Spontaneously formed 3D tumoroids obtained from the recurrent mass have also been characterized. The results prove the power of combining C…
Präpositionale Wortgruppen im Altspanischen: 13.-15. Jahrhundert
2013
Der Untersuchungsgegenstand dieser Dissertation sind präpositionale Wortgruppen (PWG) (locuciones prepositivas) in kastilischen Texten aus dem Mittelalter. Ziel dieser Arbeit ist eine kontrastive Analyse von PWG an Hand von zwei Diskurstraditionen, einer juristischen und einer historischen, während des 13., 14. und 15.Jahrhunderts. Das Hauptkorpus beinhaltet zu jedem Jahrhundert einen juristischen und einen chronistischen Text. Um der Gefahr der einseitigen Konzentration auf juristische und chronistische Texte zu entgehen, werden für jedes Jahrhundert ein zusätzlicher Text aus der Gattung der Literatur ausgewertet (Calila e Dimna, El Conde Lucanor und La Celestina). Ausgangspunkt dieser Arb…
Israel. Política económica en Israel
2018
This document presents the forecast of macroeconomic developments compiled from different sources as World Bank, International Monetary Fund, Bank of Israel, OECD, etc., in December 2018 regarding the main macroeconomic variables—GDP, inflation, unemployment, foreign trade and the real growth rate. According to international institutions staff forecast, gross domestic product (GDP) and other main macroeconomic indicators are projected till 2018 final results. We analyse the main economic data for a five years period in order to study the yearly results of the economy of Israel. Este documento presenta el pronóstico del desarrollo macroeconómico general de Israel, a parti…
Crystal structure of 12-benzylsulfanyl-2,9-dibromo-6H-dibenzo[b,g][1,8]naphthyridin-11-one
2015
The hetero-tetra-cene skeleton of the title mol-ecule, C23H14Br2N2OS, is defined by linear annulation of four six-membered rings, including two N heteroatoms. This moiety is nearly planar (r.m.s. deviation = 0.055 Å), with a slight twist of 4.1 (2)° between the two halves of the aromatic system. The dihedral angle between the least-squares plane of the skeleton and the benzyl group is 24.5 (3)°; the C-S-C angle involving the benzyl-sulfanyl group is 99.2 (4)°. In the crystal, mol-ecules are π-stacked in an anti-parallel fashion along [110], with a distance between the aromatic planes of 3.47 (2) Å. Inter-molecular N-H⋯O hydrogen bonds form chains extending parallel to [001] and bridge the a…
Treatment of a stage III rima glottidis patient with the oncolytic virus Rigvir: A retrospective case report: Erratum.
2019
Abstract Rationale: Of all the parts of the larynx, the glottis has the highest frequency of cancer. With disease progression, the vocal cord movement is affected and for advanced stages its anatomical and functional preservation is rarely achievable, if at all. Patient concerns: Here we describe a 72-year-old patient who presented with hoarseness for a year and was only able to whisper. Diagnosis: A computed tomography (CT) scan of the vocal cords (without contrast) showed higher density tissue. Histological examination disclosed a well-differentiated verrucous squamous cell carcinoma of the glottis. Interventions: The patient was treated with the oncolytic ECHO-7 virus Rigvir without any …
Use of a Perioperative Web-Based Exercise Program for a Patient with Barrett’s Carcinoma Scheduled for Esophagectomy
2019
A poor preoperative functional capacity increases the perioperative risk. Therefore, a web-based exercise approach has been initiated for a careful supervision and individual support of patients during their perioperative cancer therapy. Here, we present the data of a 57-year-old patient, scheduled for esophagectomy. Beside a five-week neoadjuvant chemoradiotherapy (CRT), the patient performed 10 weeks of a web-based prehabilitation exercise training (preconditioning) and continued the exercise program for 14 weeks after surgery. The patient performed 42 of 44 recommended training sessions in the preconditioning period in his home environment. This corresponds to a mean of 131 (±38) min of …
Hacia la ley europea del clima: las evaluaciones científicas y el futuro papel de las respuestas jurídicas de los estados miembros
2021
Los problemas climáticos son temas persistentes y omnipresentes dentro de las políticas y legislaciones contemporáneas, que exigen un enfoque interdisciplinario para promover soluciones jurídicas adecuadas para la complejidad del tema. Paradójicamente, las propagandas negacionistas, lejos de bloquear las acciones climáticas, las han propiciado, lo que ha llevado al establecimiento de un organismo científico super partes que reconociese las cuestiones climáticas a través de informes científicos avanzados: el Grupo Intergubernamental de Expertos sobre el Cambio Climático de la ONU (IPCC). Desde entonces, muchos países han usado los hallazgos del IPCC como base científica para desarrollar polí…
Declaration of will of persons with disabilities in the general theory of legal act and the new perspective based on supports. A study of peruvian law
2021
Indexado en Redib La Convención sobre los Derechos de las Personas con Discapacidad ha supuesto, en términos generales, un replanteamiento de la idea de autonomía de la voluntad al reconocer plena capacidad jurídica en todo sujeto con independencia de su discapacidad. Esta nueva realidad viene a modificar el modo de conceptuar e interpretar la declaración de voluntad en la teoría general del acto jurídico, y muy en especial, cuando la capacidad natural de conocer y querer puede venir naturalmente limitada por una discapacidad psíquica o por un estado de coma. La formación interna de la voluntad y su manifestación se vuelve un asunto complejo, sobre todo cuando los apoyos podrían no ser gara…
Corporate social responsibility reporting and institutional theory
2016
Objeto: La investigación sobre divulgación de información de sostenibilidad se ha centrado en el ámbito de la empresa, siendo escasos los trabajos que analizan las diferencias entre países. El objetivo es identificar los factores que explican las diferencias en el suministro de información de sostenibilidad a nivel macroeconómico. Diseño/metodología/enfoque: La muestra incluye 9,570 memorias elaboradas en el marco de la Global Reporting Initiative en 53 países en el periodo 2007-2012. La información para cada país se ha estandarizado por millón de habitantes en cada año. Se han utilizado modelos de regresión múltiple para estudiar la incidencia de la gobernabilidad, la cultura y la globaliz…